Clinical Trials on Nonresectable Pancreatic Cancer

Total 55401 results

National Cancer Institute (NCI)

Completed

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Pancreas Cancer | Cancer of Pancreas | Cancer of the Pancreas

United States
Clinical Hospital Colentina
Iuliu Hatieganu University of Medicine and Pharmacy; University of Medicine... and other collaborators

Completed

EUS vs. MDCT in Pancreatic Malignancy (EUSPACT)

Resectable Pancreatic Cancer

Romania
Eli Lilly and Company
AstraZeneca

Completed

A Study of Galunisertib (LY2157299) and Durvalumab (MEDI4736) in Participants With Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

Spain, United States, Korea, Republic of, France, Italy
Fudan University

Recruiting

Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer (PTCA199-4)

Metastatic Pancreatic Cancer | Terminal Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Incyte Corporation

Withdrawn

Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancreatic Ductal Cancer

Colorectal Cancer Metastatic | Pancreatic Cancer Metastatic

United States
Emory University
National Cancer Institute (NCI)

Active, not recruiting

Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Advanced Pancreatic Adenocarcinoma

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Terminated

Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Targeting Pancreatic Cancer With Sodium Glucose Transporter 2 (SGLT2) Inhibition

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Washington University School of Medicine
Ipsen

Completed

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Malignant Gastrointestinal Neoplasm | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Gallbladder Carcinoma | Stage IV Gallbladder Cancer | Stage IV Gastric Cancer | Stage IIIA Gallbladder Cancer | Stage... and other conditions

United States
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Germline Mutations Associated With Hereditary Pancreatic Cancer in Unselected Patients With Pancreatic Cancer in Mexico

Pancreatic Cancer | Pancreatic Adenocarcinoma

Mexico
Icahn School of Medicine at Mount Sinai
Patient-Centered Outcomes Research Institute

Completed

Improving Goals of Care Discussion in Advanced Cancer Patients

Melanoma | Glioblastoma | Colorectal Cancer | Cancer of Pancreas | Cancer of Stomach | Head or Neck Cancer | Stage III | Esophageal | Stage IV | Lung Cancers | Pancreatic Cancers | Primary Stage IV Hepatobiliary

United States
Asan Medical Center

Recruiting

mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma (SABER)

Pancreatic Adenocarcinoma | Pancreatic Cancer Non-resectable

Korea, Republic of
Australasian Gastro-Intestinal Trials Group
University of Sydney

Active, not recruiting

The ASCEND Study: Gemcitabine and Nab-Paclitaxel With CEND-1/LSTA1 or Placebo in Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma (ASCEND)

Pancreatic Ductal Adenocarcinoma | Metastatic Pancreatic Cancer

Australia, New Zealand
Seoul National University Hospital
Seoul St. Mary's Hospital; Seoul National University Bundang Hospital; SMG-SNU... and other collaborators

Not yet recruiting

NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer)

Resectable Pancreatic Cancer | Effects of Chemotherapy | Neoadjuvant Chemotherapy

Korea, Republic of
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma

Familial Pancreatic Cancer

United States
Baki Topal
AstraZeneca

Active, not recruiting

Progression-free Survival After MWA Plus Durvalumab and Tremelimumab for Unresectable Locally Advanced Pancreatic Cancer (MIMIPAC)

Pancreatic Cancer Non-resectable

Belgium
Ashish Manne
Ohio State University; NovoCure GmbH

Recruiting

A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer

United States
Washington University School of Medicine

Completed

Epidural Analgesia Use in Pancreatic Resections (E-PRO I)

Pancreatic Cancer | Pancreas Cancer | Pancreas Neoplasms | Cancer of Pancreas | Cancer of the Pancreas

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients With Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
Case Comprehensive Cancer Center

Recruiting

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

Resectable Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer | Decitabine | Adebrelimab (SHR-1316)

China
State University of New York - Downstate Medical...

Recruiting

Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer (C3)

Pancreatic Cancer Metastatic

United States
Copenhagen University Hospital at Herlev
Odense University Hospital; Aarhus University Hospital; University of Copenhagen

Recruiting

Implementing ctDNA and Circular DNA in Patients With Localized Pancreatic Cancer (CIRCPAC)

Resectable Pancreatic Cancer

Denmark
German Cancer Research Center

Not yet recruiting

Perioperative Platelet Inhibition With Acetylsalicylic Acid in Patients With Resectable Tumors of the Pancreatic Head (ASAP)

Pancreatic Cancer Resectable
iOnctura

Recruiting

A Study to Assess an ATX Inhibitor (IOA-289) in Patients With Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

Italy, United Kingdom
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Safety, Pharmacokinetics and Efficacy of CT-707, Toripalimab and Gemcitabine in Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

China
Beth Israel Deaconess Medical Center
Washington University School of Medicine; Rush University Medical Center; Wake... and other collaborators

Recruiting

Pancreatic Cancer Screening for At-risk Individuals (PancreasScan)

Pancreatic Cancer, Adult

United States
Fudan University

Unknown

Ntraperitoneal Thermal Perfusion Combined With Chemotherapy Versus Chemotherapy

Advanced Pancreatic Cancer

China
Asan Medical Center
Ulsan University Hospital; Bundang CHA Hospital

Completed

Retrospective Analysis of 2nd-line Nab-Paclitaxel + Gemcitabine After 1st-line FOLFIRINOX in Pancreatic Cancer

Pancreatic Cancer | Metastatic Pancreatic Cancer

Korea, Republic of
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Unknown

Efficacy and Safety of Pegylated Recombinant Human Granulocyte Stimulating Factor in Secondary Prevention of Albumin Paclitaxel Combined With S-1 in the First-line Treatment of Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

China
Yale University

Completed

Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer (FOLFIRINOX)

Pancreatic Cancer | Metastatic Pancreatic Cancer

United States
SCRI Development Innovations, LLC
Celgene Corporation

Completed

Lenalidomide With Gemcitabine in Treatment of Untreated Advanced Carcinoma of the Pancreas

Metastatic Pancreatic Cancer

United States
Arbeitsgemeinschaft medikamentoese Tumortherapie
Medical University of Graz; Bionorica SE; Unidata Geodesign

Active, not recruiting

Efficacy and Safety of Dronabinol in the Improvement of Chemotherapy-induced and Tumor-related Symptoms in Advanced Pancreatic Cancer

Chemotherapy-induced Nausea and Vomiting | Pancreatic Cancer Metastatic | Pancreatic Cancer Non-resectable

Austria, Germany
Amsterdam UMC, location VUmc
Maastricht University Medical Center; Erasmus Medical Center; St. Antonius Hospital

Not yet recruiting

Neoadjuvant Triple Treatment for Borderline Resectable Pancreatic Cancer (PREOPANC-5) (PREOPANC-5)

Borderline Resectable Pancreatic Cancer
Peking Union Medical College Hospital

Recruiting

Anlotinib Plus Anti-PD-1 Antibody AK105 for Advanced Pancreatic Cancer

Anlotinib | Anti-PD-1 Antibody | Advanced Pancreatic Cancer

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors

Metastatic Pancreatic Neuroendocrine Tumor | Unresectable Pancreatic Neuroendocrine Carcinoma

United States
MapKure, LLC

Recruiting

A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Colorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Australia, United States
Geistlich Pharma AG
Translational Drug Development

Recruiting

Trial to Evaluate Safety and Tolerability of GP-2250 in Combination With Gemcitabine

Pancreatic Cancer, Adult

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer

Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Extensive Stage Small Cell Lung Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage II Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage I Pancreatic Cancer | Stage II Non-small Cell Lung Cancer | Stage III Colon Cancer and other conditions

United States
National Cancer Institute (NCI)

Completed

Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
CNAO National Center of Oncological Hadrontherapy
Foundation IRCCS San Matteo Hospital

Recruiting

Carbon Ions Radiation Therapy for Resectable or Borderline Resectable Pancreas Adenocarcinoma (PIOPPO)

Pancreas Adenocarcinoma | Resectable Pancreatic Cancer | Cancer of Pancreas

Italy
Washington University School of Medicine
National Cancer Institute (NCI); Leidos; UNICO Foundation

Recruiting

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Washington University School of Medicine
National Cancer Institute (NCI); The Foundation for Barnes-Jewish Hospital; Celldex...

Terminated

Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
University of Nebraska
National Cancer Institute (NCI); Adherex Technologies, Inc.

Completed

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Pancreatic Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage IIIA Gallbladder Cancer | Stage IIIB Gallbladder Cancer | Stage IVA Gallbladder Cancer | Stage IVB Gallbladder Cancer | Gallbladder Adenocarcinoma and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
University of California, Davis
Bristol-Myers Squibb; National Cancer Institute (NCI); Dynavax Technologies Corporation

Completed

SD-101, Nivolumab, and Radiation Therapy in Treating Patients With Chemotherapy-Refractory Metastatic Pancreatic Cancer

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Refractory Pancreatic Adenocarcinoma

United States

Clinical Trials on Nonresectable Pancreatic Cancer

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