Clinical Trials on Normal Renal Function in United Kingdom

Total 6705 results

Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Guy's and St Thomas' NHS Foundation Trust
Astellas Pharma Europe Ltd.

Unknown

RituxiMab INDuction in Renal Transplantation (ReMIND)

Function of Renal Transplant

United Kingdom
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
Martin Angst

Completed

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

Normal Immune Cell Function

United States
Englewood Hospital and Medical Center

Withdrawn

Neuropsychological Testing Using Mobile Devices

Inpatients With Normal Neurological Function

United States
University of Edinburgh
Kidney Cancer UK

Terminated

Heme Arginate in Transplantation Study (HOT2)

Renal Transplant Rejection | Renal Transplant Failure

United Kingdom
University Hospitals Coventry and Warwickshire...

Completed

The Heart Failure With Preserved Ejection Fraction (HFpEF) Pathophysiology Study. (IDENTIFY-HF)

Heart Failure With Normal Ejection Fraction

United Kingdom
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants With Normal Renal Function

Renal Impaired | Gilteritinib | Normal Renal Function | Pharmacokinetics of ASP2215

United States, Bulgaria
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
Vitae Pharmaceuticals, Inc.
Brigham and Women's Hospital

Completed

Direct Renin Inhibition and the Kidney

Renal Function

United States
VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
Geisinger Clinic

Completed

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

Abnormal Liver Function

United States
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
University of Louisville

Completed

Louisville Cooperative Tissue Biorepository (LCTB)

Normal and Abnormal Tissue

United States
Stanford University

Completed

Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant (RTphylline)

Function of Renal Transplant

United States
Imperial College London

Completed

Effects of Obesity Surgery on Renal Function

Impaired Renal Function

United Kingdom
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
Sanofi

Completed

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Germany
Principia Biopharma, a Sanofi Company

Completed

A Study to Evaluate the Effect of Mild and Moderate Hepatic Impairment on the Single-Dose Pharmacokinetics of Rilzabrutinib (PRN1008)

Healthy Volunteers | Hepatic Function Abnormal

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
University of California, San Diego

Completed

Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients

Hormone Replacement Therapy | Renal Function | Transgender

United States
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); American Society for Transplantation

Withdrawn

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

High Blood Pressure | Liver Transplant | Renal Function Abnormal

United States
University of Reading
Danisco

Completed

A Study of a Prebiotic, a Probiotic and a Synbiotic Upon the Gut Microbiota and Immune Response of Healthy Volunteers (XOS)

Gut Microbiota | Immune Function | Bowel Function | Plasma Lipids

United Kingdom
Schroppel, Bernd, M.D.
Alexion Pharmaceuticals

Terminated

A Study of the Activity of Eculizumab for Prevention of Delayed Graft Function In Deceased Donor Kidney Transplant

Delayed Function of Renal Transplant

United States
University Hospital Southampton NHS Foundation...
University of Southampton

Completed

Prebiotics and Immune Function in Middle Aged Humans

Immune Function

United Kingdom
University of Glasgow

Recruiting

Short-term Sleep Restriction on Taste Preference and Perception

Sleep Restriction | Normal Sleep

United Kingdom
Heidelberg Engineering GmbH

Recruiting

The Heidelberg Engineering ANTERION Software Comparison Precision and Agreement Study

Eyes With Normal Anterior Segment | Eyes With Abnormal Anterior Segment

United States
University of Bath

Completed

Does Exercise Snacking Improve Muscle Function in Older Adults?

Muscle Function

United Kingdom
University Hospital Southampton NHS Foundation...

Completed

Preconception Maternal Iodine Status and Offspring Cognitive Function:

Cognitive Function

United Kingdom
University College London Hospitals

Terminated

Conservative Versus Surgical Management of Idiopathic Normal Pressure Hydrocephalus (INPH)

Normal Pressure Hydrocephalus

United Kingdom
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function (MODERATE)

Obesity | Overweight | Blood Pressure | Renal Function | Endothelial Function

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.

Renal Function | Liver Transplant

United States, Germany, Spain, Belgium, France, Hungary, Australia, Sweden, Italy, Canada, United Kingdom, Denmark
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
NicOx

Completed

A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function (HCT3012-X-106)

Renal Failure

United States
Scarborough General Hospital

Unknown

SNE1725: Can Oral Glutamine Facilitate Early Return of Gut Function

Gut Function

United Kingdom
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Renal Function

Impaired Renal Function

United States
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
Shire

Completed

Study of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Function

Impaired Renal Function

United States
Eloxx Pharmaceuticals, Inc.
Syneos Health

Completed

A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02

Impaired Renal Function

United States
University of Reading
Wild Blueberry Association of North America (WBANA)

Recruiting

Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults

Executive Function | Mood | Affect

United Kingdom
Loughborough University
University Hospitals of Derby and Burton NHS Foundation Trust; University Hospitals...

Completed

The Influence of High Impact Exercise on Musculoskeletal Health in Older Men (Hiphop)

Bone Strength | Neuromuscular Function

United Kingdom
University of Exeter
Innovate UK; Mitocholine Ltd

Recruiting

The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function (MCh1)

Cognitive Function | Exercise Performance

United Kingdom
University of Reading
Danisco

Completed

The Effect of a Prebiotic, Probiotic and Synbiotic on the Gut Microbiota and Immune Response of Older Volunteers (GOS)

Gut Microbiota | Immune Function

United Kingdom
Northumbria University

Completed

Effects of Epigallocatechin Gallate (EGCG) in Healthy, Young Adults

Cognitive Function | Mood

United Kingdom

Clinical Trials on Normal Renal Function in United Kingdom

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