Clinical Trials on Normal and Abnormal Tissue in Singapore

Total 439 results

National University Hospital, Singapore
Centre for Health Services and Policy Research

Completed

Multidisciplinary Team Care in Rheumatoid Arthritis

Rheumatoid Arthritis | Multidisciplinary Communication

Singapore
Sidney Kimmel Comprehensive Cancer Center at Johns...
Singapore Cancer Society

Terminated

Protein Biomarker in Hepatocellular Carcinoma

Liver Cirrhosis | Hepatitis | Hepatocellular Carcinoma | Normal Volunteers

Singapore
National University Hospital, Singapore
GlaxoSmithKline

Recruiting

Sequential Belimumab and T-cell Based Therapy in SLE

Systemic Lupus Erythematosus

Singapore
National University Hospital, Singapore

Unknown

Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomas (NKEXPSARC)

Ewing Sarcoma | Rhabdomyosarcoma

Singapore
National University Hospital, Singapore

Completed

A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore

Gastrointestinal Stromal Tumors

Singapore
National University Hospital, Singapore

Unknown

Chemotherapy on Methylation Patterns in Breast Tumor Tissue Correlating With Clinical Response and Outcomes

Breast Tumor Tissue

Singapore
National University Hospital, Singapore
National University, Singapore

Completed

A Soft Robotics Approach Towards Finger Joint Deformities in Rheumatic Diseases

Osteoarthritis

Singapore
Pfizer

Completed

A Study To Compare The Amount Of CP-690,550 That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of Two Different Strength Tablets Of CP-690,550

Arthritis, Rheumatoid

Singapore
Singapore General Hospital

Completed

A Musculoskeletal Ultrasound Program to Improve Disease Modifying Anti-Rheumatic Drugs Adherence in Rheumatoid Arthritis

Rheumatoid Arthritis

Singapore
Singapore General Hospital

Terminated

Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study

Rheumatoid Arthritis

Singapore
National University Hospital, Singapore

Recruiting

A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)

Breast Cancer

Singapore
National University Hospital, Singapore

Unknown

The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging

Photoaging

Singapore
Pfizer

Completed

A Study To Compare The Amount Of Tasocitinib (CP-690,550) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of Three Different Tablet Versions Of Tasocitinib (CP-690,550)

Rheumatoid Arthritis

Singapore
Pfizer

Completed

A Study To Evaluate The Effect Of Food On How Tasocitinib (CP-690,550) Is Absorbed And Moves Through The Body Following Oral Administration Of Tasocitinib (CP-690,550) Tablets To Healthy Subjects

Rheumatoid Arthritis

Singapore
National University Hospital, Singapore

Unknown

Effects of Probiotics in Preventing Oral Mucositis

Head-and-neck Cancer

Singapore
KK Women's and Children's Hospital

Active, not recruiting

Use of Axillary Ultrasound to Guide Breast Cancer Management in the Genomic Assay Era

Axillary Ultrasound

Singapore
Duke University

Completed

Family History in a Singapore Oncology Population

Breast Cancer

Singapore
National University Hospital, Singapore

Unknown

A Retrospective Study of C-kit Mutation Status in Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib.

Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib

Singapore
National Cancer Centre, Singapore

Recruiting

Using QPOP to Predict Treatment for Sarcomas and Melanomas

Melanoma | Sarcoma

Singapore
Eli Lilly and Company
Incyte Corporation

Completed

A Relative Bioavailability and Food Effect Study of New Formulations

Arthritis, Rheumatoid | Chronic Inflammatory Disorder

Singapore
Singapore General Hospital

Unknown

Clinical Trial of Probiotics in Systemic Sclerosis Associated Gastrointestinal Disease

Systemic Sclerosis

Singapore
Singapore General Hospital
National University Hospital, Singapore; Tan Tock Seng Hospital; Nanyang Technological... and other collaborators

Recruiting

Evaluating Gut Imaging and Stool Biomarkers in Patients With Scleroderma-associated Gastrointestinal Disease (Pre Med SSc GI)

Systemic Sclerosis | Scleroderma

Singapore
Duke-NUS Graduate Medical School

Recruiting

Marital Satisfaction and Sexual Health of Female Cancer Patients in Singapore (RISE)

Breast Cancer | Gynecologic Cancer

Singapore
Paracrine Therapeutics Dermatology Pte. Ltd.
National University Hospital, Singapore

Completed

Safety and Tolerability Study of MSC Exosome Ointment

Psoriasis

Singapore
Tan Tock Seng Hospital

Terminated

Evaluation of Skin Cleansers and Skin Protectants in Management of Incontinence-associated Dermatitis

Incontinence-associated Dermatitis

Singapore
Singapore General Hospital

Unknown

Knee Articular Cartilage Repair: Cartilage Autograft Implantation System Versus Conventional Microfracture (CAIS)

Osteochondritis Dissecans | Other Articular Cartilage Disorders

Singapore
National University Hospital, Singapore

Unknown

Comparative Genomic and Genetic Analysis of Paired Primary Breast - Metastatic Tumor Specimens Using High-throughput Platforms

Breast Cancer

Singapore
Cosmetique Active International

Not yet recruiting

Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins

Hyperpigmentation

Singapore
KK Women's and Children's Hospital

Completed

Comparison of Epidural Oxycodone and Epidural Morphine

Pruritus

Singapore
Tan Tock Seng Hospital
Singapore General Hospital; University of Sydney; University of Southern Denmark and other collaborators

Active, not recruiting

Collaborative Model of Care Between Orthopaedics and Allied Healthcare Professionals Trial (CONnACT)

Osteoarthritis

Singapore
National Cancer Centre, Singapore

Completed

Clinical Study of Metronomic Oral Cyclophosphamide in Patients With Advanced Sarcomas

Sarcoma

Singapore
Institute of Bioengineering and Bioimaging (IBB)
National Skin Centre, Singapore

Recruiting

Non-invasive Photoacoustic Imaging of Skin Inflammatory Disorders With Machine Learning-assisted Scoring

Psoriasis | Eczema

Singapore
Pfizer

Completed

A Study To Estimate The Amount Of CP-690,550 (Study Drug) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of CP-690,550 In Tablet Form

Healthy

Singapore
Singapore Clinical Research Institute
Singapore General Hospital; Duke-NUS Graduate Medical School

Terminated

The Effect of 90-day Oral Testosterone Therapy in Chinese Males With Type 2 Diabetes (T2DM) (OTEST)

Assess the Effects of a the 90-day Oral TS Study Regimen on PSA, IPSS, Haemoglobin and Haematocrit, and to Assess Adverse and Serious Adverse Events.

Singapore
Tan Tock Seng Hospital
Khoo Teck Puat Hospital; National Healthcare Group, Singapore; Woodlands Health...

Not yet recruiting

CONNACT OA Knee Cohort (CONNACT)

Osteoarthritis, Knee

Singapore
National University Hospital, Singapore
Mundipharma Pte Ltd.

Unknown

The Efficacy and Safety of 3% Povidone-Iodine in Acne Therapy

Acne

Singapore
National Cancer Centre, Singapore
National University of Singapore

Terminated

Diffuse Optical Tomography (DOT) for Monitoring Response to Neoadjuvant (Preoperative) Chemotherapy in Breast Cancer (DOT)

Breast Neoplasms

Singapore
National Skin Centre

Recruiting

Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars

Wound Heal | Wound | Keloid

Singapore
Lynk Biotechnologies Pte Ltd
T&T Family Health Clinic and Surgery, Singapore; Temasek Polytechnic School...

Completed

Transdermal Delivery of Glucosamine to the Synovial Fluid of Male and Female With Knee Osteoarthritis

Osteoarthritis, Knee

Singapore
Tan Tock Seng Hospital
National Healthcare Group, Singapore; Singapore Chung Hwa Medical Institution

Not yet recruiting

Heat and Acupuncture Randomised Controlled Trial to Manage Osteoarthritis of the Knee (HARMOKnee)

Osteoarthritis, Knee

Singapore
National University Hospital, Singapore
National University of Singapore

Recruiting

Pulsed Electromagnetic Fields (PEMFs) - A Highly Selective Breast CAncer Treatment pLatform (PASCAL)

Breast Cancer

Singapore
Singapore General Hospital

Recruiting

A Comparison of Total Knee Replacement Patients Using the Zimmer-Biomet Persona Total Knee System With Different Inserts

Knee Osteoarthritis | Osteoarthritis, Knee

Singapore
Tan Tock Seng Hospital

Completed

Community Based Rehabilitation Model After Total Knee Replacement

Knee Osteoarthritis

Singapore
National University Hospital, Singapore
Eisai Co., Ltd.

Unknown

Neoadjuvant Lenvatinib Combined With Letrozole in Hormone Receptor Positive Breast Cancer

Breast Cancer

Singapore
Tan Tock Seng Hospital

Completed

Experience and Technology Acceptance of Older Adults Towards a Gamified Rehabilitative Device Prototype

Knee Osteoarthritis

Singapore
National Cancer Centre, Singapore

Completed

Study of Neoadjuvant Docetaxel and Cyclophosphamide in Locally Advanced or Node Positive Primary Breast Cancer With Companion Pharmacokinetic and Pharmacogenomic Analyses

Breast Cancer

Singapore
National University Hospital, Singapore

Unknown

Dose-confirmation Study of ASLAN001 Combined With Weekly Paclitaxel and Carboplatin in Advanced Solid Tumours, Followed by a Study in Patients With Stage I-III HER2 Positive Breast Cancer

Breast Cancer

Singapore
National University Hospital, Singapore

Unknown

Randomized Study of Doxorubicin and Cyclophosphamide With or Without Intermittent Sunitinib in the First-line Treatment of Locally Advanced or Metastatic Breast Cancer Patients With Measurable Primary Breast Tumor

Breast Cancer

Singapore
National University Hospital, Singapore

Unknown

Study of Circulating and Tumor Biomarkers in Breast Cancer Patients

Breast Cancer

Singapore
National University Hospital, Singapore

Unknown

Using National University Cancer Institute of Singapore (NCIS) Registry to Measure Time Trends in Quality of Care for Breast Cancer Patients in a National Cancer Centre

Breast Cancer

Singapore

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