Clinical Trials on Oesophageal Carcinoma

Total 26906 results

City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Pilot Trial of CRLX101 in Treatment of Patients With Advanced or Metastatic Stomach, Gastroesophageal, or Esophageal Cancer That Cannot be Removed by Surgery

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Squamous Cell Carcinoma of the Esophagus | Adenocarcinoma of the Esophagus | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma... and other conditions

United States
University of Oxford
Merck KGaA, Darmstadt, Germany

Completed

M6620 Plus Standard Treatment in Oesophageal and Other Cancer (CHARIOT)

Solid Tumor | Oesophageal Adenocarcinoma | Squamous Cell Carcinoma

United Kingdom
Hospital Authority, Hong Kong
The University of Hong Kong

Unknown

A Study of the Use of High-dose Proton Pump Inhibitor for the Treatment of Gastro-oesophageal Reflux Related Non-cardiac Chest Pain - a Randomized Double-blind Placebo-controlled Study

Chest Pain

China
Taipei Veterans General Hospital, Taiwan

Recruiting

Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices (P-HCC)

Hepatocellular Carcinoma | Bleeding Esophageal Varices

Taiwan
Novartis Pharmaceuticals

Completed

A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer

Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer | HER2 + Gastric Cancer

Taiwan, Spain, Canada, Korea, Republic of, United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer (TRAP-2)

Esophageal Cancer | Esophageal Adenocarcinoma

Netherlands
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study of Docetaxel for Injection (Albumin-bound) and SG001 in Combination With Cisplatin and Simultaneous Radiotherapy for Locally Advanced Unresectable Esophageal Squamous Carcinoma.

Locally Advanced Unresectable Esophageal Squamous Carcinoma

China
Henan Cancer Hospital

Completed

Neoadjuvant Chemotherapy Compared With Surgery for Esophageal Carcinoma

Esophagus Cancer

China
Hunan Province Tumor Hospital
Sun Yat-sen University; Cancer Institute and Hospital, Chinese Academy of Medical...

Unknown

Diffusion-weighted Magnetic Resonance Imaging (DW-MRI )for Early Response Assessment in Patients With Esophageal Cancer

Esophageal Carcinoma

China
Stanford University

Terminated

Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer

Adenocarcinoma | Carcinoma, Squamous Cell | Esophageal Cancer | Esophageal Neoplasms

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal Cancer Receiving Combination Chemotherapy

Stage IIIA Esophageal Adenocarcinoma | Stage IIIB Esophageal Adenocarcinoma | Stage IIIC Esophageal Adenocarcinoma | Stage IIB Esophageal Adenocarcinoma | Stage IB Esophageal Adenocarcinoma | Stage IIA Esophageal Adenocarcinoma

United States
Fudan University

Completed

S1 Combined With Cisplatin in Treatment of Recurrence/Metastasis of ESCC Open-label Single Center Phase II Clinical Study

Esophageal Squamous Cell Carcinoma

China
Qingdong Cao

Unknown

Radical Resection of Single-hole Inflatable Mediastinal Mirror Synchronization With Laparoscopic Esophageal Carcinoma

Esophagus Cancer

China
Imperial College London
Barking, Havering and Redbridge University Hospitals NHS Trust; Imperial College... and other collaborators

Recruiting

Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors (MAPLES)

Quality of Life | Oesophageal Cancer | Bacterial Overgrowth

United Kingdom
Lisette Nixon

Completed

ROCS (Radiotherapy After Oesophageal Cancer Stenting) Study (ROCS)

Oesophageal Cancer

United Kingdom
CDx Diagnostics

Completed

Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-Dimensional Tissue Analysis (WATS3D) For the Detection of High Grade Esophageal Dysplasia and Adenocarcinoma

Barrett Esophagus | Esophageal Adenocarcinoma | Esophageal Dysplasia

Belgium
National Cancer Institute (NCI)

Terminated

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Lung Cancer | Carcinoma, Esophageal | Malignant Pleural Mesotheliomas

United States
Peking University Cancer Hospital & Institute

Unknown

Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions

Esophageal Squamous Cell Carcinoma | Mild Dysplasia of Esophagus | Moderate Dysplasia of Esophagus | Severe Dysplasia of Esophagus | Carcinoma in Situ of Esophagus

China
First Affiliated Hospital of Chengdu Medical College

Unknown

A Clinical Research of CAR T Cells Targeting EpCAM Positive Cancer (CARTEPC)

Gastric Cancer | Pancreatic Cancer | Prostate Cancer | Colon Cancer | Esophageal Carcinoma | Hepatic Carcinoma

China
Birmingham Women's and Children's NHS Foundation...

Not yet recruiting

Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula (iTOF)

Tracheo-Esophageal Fistula With Atresia of Esophagus

United Kingdom
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease | Metaplasia | Barrett Esophagus | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Dysplasia

United States
Henan Cancer Hospital
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP)

Esophageal Carcinoma | Lung Cancer, Nonsmall Cell

China
Hospital Universitari de Bellvitge
University of Barcelona

Recruiting

Robot-assisted Thoracic Approach Versus Open Transthoracic Esophagectomy . (CIR·ROB)

Postoperative Complications | Esophageal Cancer | Esophageal Carcinoma

Spain
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Unknown

Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus (ROCOCO)

Carcinoma of the Oesophagus

United Kingdom
P.O. Witteveen
Merck KGaA, Darmstadt, Germany

Terminated

Study of Combination of Cetuximab and Radiotherapy Added to the Standard Treatment for Oesophageal Adenocarcinoma (TRACC)

Resectable Esophageal Cancer

Netherlands
University of Göttingen

Suspended

Dental Erosion in Patients With Gastro-oesophageal Reflux

Dental Erosion
Guangdong Provincial People's Hospital
Haplox

Not yet recruiting

Efficacy Evaluation and Recurrence Monitoring of Therapy for Esophageal Squamous Cell Carcinoma Based on ctDNA-MRD.

Esophageal Squamous Cell Carcinoma | Minimal Residual Disease

China
Tianjin Medical University Cancer Institute and...

Not yet recruiting

An Exploratory Clinical Study of SHR6390 and SHR1020 in the Treatment of Esophageal Squamous Cell Carcinoma After Progression on PD-1 Antibody

Esophageal Squamous Cell Carcinoma | Progression to PD-1 Antibody

China
Shanghai Zhongshan Hospital

Completed

Machine Learning to Predict Lymph Node Metastasis in T1 Esophageal Squamous Cell Carcinoma

Lymph Node Metastasis

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC

Chemotherapy Effect | Esophageal Squamous Cell Carcinoma | Side Effect of Drug

China
Shanghai Chest Hospital

Unknown

Apatinib in the Treatment of Recurrence or Metastasis of Esophageal Cancer

Recurrence | Metastasis | Esophageal Squamous Cell Carcinoma | Apatinib

China
Hamamatsu University

Completed

Low-Dose Nedaplatin (CDGP:Cis-Diammine-Glycolatoplatinum)/5-FU Combined With Radiation for Esophageal Cancer

Esophageal Cancer | Squamous Cell Carcinoma

Japan
Sichuan Cancer Hospital and Research Institute

Recruiting

Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest.

Non-small Cell Lung Cancer | Esophageal Squamous Cell Carcinoma

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Yoga Program for Improving the Quality of Life in Couples Coping With Cancer

Malignant Solid Neoplasm | Lung Carcinoma | Esophageal Carcinoma | Malignant Head and Neck Neoplasm

United States
Novartis Pharmaceuticals

Terminated

Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies

Colorectal Cancer | Gastrointestinal Stromal Tumors | Non-small Cell Lung Carcinoma | Head and Neck Squamous Cell Carcinoma | Esophageal SCC

United States, Germany, Spain, Singapore, Australia, Hong Kong, Belgium, Japan, China
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

EsophaCap for the Detection of Early Esophageal Carcinoma

Gastric Cancer | Esophageal Cancer | Barrett Esophagus

United States
Centre Hospitalier Universitaire de Besancon

Terminated

Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer (IPEC-GC)

Stomach Neoplasms | Oesophageal Junction Cancer | Lower Oesophagus Cancer

France
University Hospital, Bordeaux

Completed

Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal Reflux (PHARO)

Laryngopharyngeal Reflux | Oesophageal pH-impedance

France
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Esophageal Cytology With FISH in Detecting Esophageal Cancer

Esophagitis | Weight Loss | Gastroesophageal Reflux Disease | Dysphagia | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Dysplasia | High Grade Dysplasia in Barrett Esophagus

United States
Shanghai Henlius Biotech

Recruiting

A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC

ESCC or Esophageal Adenosquamous Carcinoma

China
Health Science Center of Xi'an Jiaotong University

Completed

Perioperative Vs. Preoperative Chemotherapy With Surgery in the Squamous Carcinoma of Esophagus

Squamous Carcinoma of Esophagus | Esophagus Disorders

China
Merck Sharp & Dohme LLC

Completed

First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590)

Esophageal Neoplasms

Taiwan, China, United States, Argentina, Australia, Brazil, Canada, Chile, Colombia, Costa Rica, Denmark, France, Germany, Guatemala, Hong Kong, Japan, Korea, Republic of, Malaysia, Peru, Romania, Russian Federation, South Africa, S... and more
Centre Georges Francois Leclerc
Federation Francophone de Cancerologie Digestive; National Cancer Institute... and other collaborators

Completed

Radiochemotherapy With and Without Dose Escalation in Patients Presenting Locally Advanced or Inoperable Carcinoma of the Oesophagus (CONCORDE)

Esophageal Cancer

France
University of Nottingham

Completed

The Accuracy and Acceptability of Magnet Assisted Capsule Endoscopy in the Diagnosis of Esophageal Pathology: a Pilot Study (MACE)

Oesophageal Varices | Barrett's Oesophagus

United Kingdom
Janssen-Cilag Pty Ltd

Completed

A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg

Gastro-oesophageal Reflux

Australia
Hoffmann-La Roche

Active, not recruiting

A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors

Metastatic Melanoma | Non-small Cell Lung Cancer (NSCLC) | Solid Tumors | Esophageal Squamous Cell Carcinoma (ESCC) | Small Cell Lung Cancer (SCLC)

United States, Korea, Republic of, Denmark, France, Spain, New Zealand
Merck Sharp & Dohme LLC

Withdrawn

First-line Esophageal Carcinoma Study With Chemo vs. Chemo Plus Pembrolizumab (MK-3475-590/KEYNOTE-590)-China Extension Study

Esophageal Neoplasms

China
National Cancer Institute (NCI)

Terminated

A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Squamous Cell Carcinoma of the Esophagus | Adenocarcinoma of the Esophagus | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma... and other conditions

United States
University of Nebraska
National Cancer Institute (NCI)

Terminated

Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer

Esophageal Adenocarcinoma | Adenocarcinoma of the Gastroesophageal Junction | Stage IIB Esophageal Cancer | Stage IIA Esophageal Cancer

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Terminated

Regorafenib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction Who Have Completed Chemoradiation Therapy and Surgery

Adenocarcinoma of the Gastroesophageal Junction | Stage IIIA Esophageal Adenocarcinoma | Stage IIIB Esophageal Adenocarcinoma | Stage IIIC Esophageal Adenocarcinoma | Stage IIB Esophageal Adenocarcinoma

United States

Clinical Trials on Oesophageal Carcinoma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in India

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations