Clinical Trials on Oropharyngeal

Total 494 results

Rigshospitalet, Denmark

Active, not recruiting

Allogeneic Mesenchymal Stem Cells for Radiation-induced Hyposalivation and Xerostomia/Dry Mouth (MESRIX-SAFETY)

Mesenchymal Stem Cells | Xerostomia | Salivary Gland Diseases | Oropharynx Cancer | Hyposalivation | Dry Mouth | Mesenchymal Stromal Cells | Xerostomia Due to Radiotherapy | Stem Cells

Denmark
Hospital de Mataró
Instituto de Salud Carlos III; Consorci Sanitari del Maresme

Recruiting

Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation (ICI20/00117)

Stroke | Oropharyngeal Dysphagia | Swallowing Disorder | Stroke, Complication

Spain
UNC Lineberger Comprehensive Cancer Center

Completed

Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx

Head and Neck Cancer | Oropharynx Cancer | Xerostomia Due to Radiotherapy

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Pancreatic Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Malignant Neoplasm | Recurrent Colorectal Carcinoma | Pancreatic Neuroendocrine Carcinoma | Malignant Head and Neck Neoplasm | Stage III Nasopharyngeal Carcinoma... and other conditions

United States
Radboud University Medical Center
University Medical Center Groningen; Maastricht University Medical Center; UMC... and other collaborators

Recruiting

Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study. (PRIMO)

Oropharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma

Netherlands
Nader Sadeghi
McGill University Health Centre/Research Institute of the McGill University...

Recruiting

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer. (NECTORS)

Oropharynx Cancer | Tonsil Cancer | Throat Cancer | Base of the Tongue Carcinoma

Canada
AHS Cancer Control Alberta
Cross Cancer Institute; Tom Baker Cancer Centre

Recruiting

p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT) (PROTEcT)

Squamous Cell Carcinoma of the Oropharynx

Canada
Universitat Internacional de Catalunya

Completed

Health Education to Caregivers to Reduce Aspiration Pneumonia (HECGPN)

Pneumonia | Malnutrition | Oropharyngeal Dysphagia

Spain
Hospital Geral de Fortaleza

Completed

Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke

Stroke, Ischemic | Dysphagia, Oropharyngeal

Brazil
Sunnybrook Health Sciences Centre

Not yet recruiting

Slow-Stream Expiratory Muscle Strength Training for Veterans With Dysphagia Living in Long-term Care

Cough | Dysphagia | Aging | Aspiration Pneumonia | Dysphagia, Oropharyngeal | Dysphagia, Progressive

Canada
M.D. Anderson Cancer Center
Sanofi

Withdrawn

Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell Carcinoma

Head and Neck Cancer | Oropharynx Cancer | Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Terminated

Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Metastatic Squamous Cell Carcinoma in... and other conditions

Canada
Pharmacyclics LLC.

Terminated

Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

Head and Neck Cancer | Oropharynx Cancer | Larynx Cancer | Hypopharynx Cancer

United States
Regenstrief Institute, Inc.
Merck Sharp & Dohme LLC; Indiana University

Completed

HPV Vaccination: Evaluation of Reminder Prompts for Doses 2 & 3

Cervical Cancer | Oropharyngeal Cancer | Genital Warts | Human Papilloma Virus Infection Type 11 | Human Papilloma Virus Infection Type 16 | Human Papilloma Virus Infection Type 18 | Human Papilloma Virus Infection Type 6

United States
Boston Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event (BRUE)

Oropharyngeal Dysphagia | Brief Resolved Unexplained Event | Apparent Life Threatening Event

United States
Lawson Health Research Institute

Active, not recruiting

A Phase II Randomized Trial for Early-stage Squamous Cell Carcinoma of the Oropharynx: Radiotherapy vs Trans-oral Robotic Surgery (ORATOR) (ORATOR)

Early-Stage Squamous Cell Carcinoma of the Oropharynx

Canada, Australia
University Medical Center Groningen

Recruiting

Immunological Function After Radiation With Either Proton or Photon Therapy (PRO-IMMUNO)

Head and Neck Cancer | Oropharynx Cancer | Larynx Cancer | HNSCC | Hypopharynx Cancer

Netherlands
University of Southern California
Sofregen Medical, Inc.

Completed

Silk Protein Microparticle-based Filler for Injection Augmentation

Dysphonia | Vocal Cord Paralysis Unilateral | Dysphagia, Oropharyngeal

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer

Subjects With p16 Positive/HPV Positive Squamous Cell Carcinomas of the Oropharynx

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III... and other conditions
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic... and other conditions

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma and other conditions

United States
HRYZ Biotech Co.

Recruiting

HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor

Cervical Cancer | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | Anal Carcinoma | Vagina Tumor | Carcinoma of Penis | Carcinoma of Vulva

China
National Cancer Institute (NCI)

Recruiting

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Cervical Cancer | Vulvar Cancer | Colon Cancer | Anal Cancer | Vaginal Cancer | Oropharyngeal Cancer | Penile Cancer | HPV | Human Papillomavirus | Neck Cancer

United States
University of Chicago
Novartis

Terminated

BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Human Papillomavirus Infection | Recurrent Oropharyngeal Squamous Cell Carcinoma | FGFR Gene Amplification | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | Recurrent Nasopharynx...

United States
Regenstrief Institute, Inc.
Merck Sharp & Dohme LLC; Indiana University

Completed

HPV Vaccination: An Investigation of Physician Reminders and Recommendation Scripts

Cervical Cancer | Oropharyngeal Cancer | Genital Warts | Human Papilloma Virus Infection Type 11 | Human Papilloma Virus Infection Type 16 | Human Papilloma Virus Infection Type 18 | Human Papilloma Virus Infection Type 6
Boston Medical Center

Completed

Integrating a Health Information Technology System for Primary and Secondary Cervical Cancer Prevention

Cervical Cancer | Vulvar Cancer | Anal Cancer | Vaginal Cancer | Oropharyngeal Cancer | Penile Cancer | Human Papillomavirus Infection | Human Papilloma Virus

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors

Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | Hypopharynx Cancer

United States
National Cheng-Kung University Hospital

Recruiting

Investigating the Association Between Microbiota and Esophageal/Oropharyngeal Cancer

Esophageal Cancer | Microbial Colonization | Oropharyngeal Neoplasms | Synchronous Neoplasm

Taiwan
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of Unknown Primary | Advanced Hypopharyngeal Squamous Cell Carcinoma | Advanced Laryngeal Squamous Cell Carcinoma | Advanced Oropharyngeal Squamous Cell Carcinoma

United States, Canada
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pulmonary Health in Children With Down Syndrome

Down Syndrome | Dysphagia, Oropharyngeal

United States
Robert L. Ferris, MD, PhD
Bristol-Myers Squibb

Active, not recruiting

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Oropharynx Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck

United States
Cairo University

Completed

Feasibility Of Oral Sensorimotor Stimulation On Oropharyngeal Dysphagia In Children With Spastic Cerebral Palsy

Physical Therapy

Egypt
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Swallowing, Speech and Quality of Life of Patients With Carcinoma of the Oropharynx

Squamous Cell Carcinoma of the Oropharynx

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases

Asthma | Pulmonary Fibrosis | Lymphangioleiomyomatosis | Pulmonary Disease | Sarcoidosis | Oropharyngeal Disease

United States
Christian Hinrichs
National Cancer Institute (NCI)

Not yet recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical Cancer | HPV-Related Malignancy | Vulvar Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Associated Cervical Carcinoma | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
The First Affiliated Hospital of Zhengzhou University

Recruiting

Effect of Botulinum Toxin Injection Into Upper Esophageal Sphincter in Patients With Medullary Infarction

Brain Stem Infarctions | Dysphagia, Esophageal | Dysphagia, Oropharyngeal

China
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage III Hypopharyngeal... and other conditions

United States
Hospital de Mataró
Nutricia Research

Recruiting

Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia (OMI)

Malnutrition | Oropharyngeal Dysphagia | Oral Disease | Dehydration | Swallowing Disorder | Respiratory Infection

Spain
Hospital de Mataró
Centro Investigación Biomédica en Red de Enfermedades Hepáticas Digestivas

Completed

Oropharyngeal Dysphagia in Patients With COVID-19

COVID-19 | Oropharyngeal Dysphagia | Nutrition | Sars-CoV2

Spain
Centre Hospitalier Universitaire de Nīmes

Completed

Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers (APPROCHE ORL)

Carcinoma, Squamous Cell | Mouth Neoplasms | Oropharyngeal Neoplasms | Hypopharyngeal Neoplasms | Laryngeal Neoplasms

France
National Cancer Institute (NCI)

Completed

Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy (MAESTRO HN)

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States, China
Nanfang Hospital, Southern Medical University

Recruiting

A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis

Radiation-induced Oropharyngeal Mucositis | Swallowing-induced Breakthrough Pain

China
Nanfang Hospital, Southern Medical University

Recruiting

A Real-world Observational Study of a Mucosal Contouring Method for Radiation-induced Oropharyngeal Mucositis

Radiation-induced Oropharyngeal Mucositis | Swallowing-induced Breakthrough Pain

China
Rigshospitalet, Denmark
The Novo Nordic Foundation

Completed

Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer

Oropharynx Cancer | Tonsil Cancer | Tonsil Hypertrophy | Tonsil Neoplasm | Tonsil Lymphoma | Base of Tongue Carcinoma | Oropharynx Neoplasm | Base of Tongue Tumor

Denmark
Christian Hinrichs

Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical Cancer | HPV-Related Malignancy | Metastatic Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
University College, London
National Institute for Health Research, United Kingdom; Myotonic Dystrophy... and other collaborators

Recruiting

Profile of Dysphagia in Myotonic Dystrophy Type 1 (DM1) (SwallowDM1)

Myotonic Dystrophy 1 | Dysphagia, Oropharyngeal

United Kingdom
Rigshospitalet, Denmark
The Novo Nordic Foundation

Recruiting

Surgeon-performed Outpatient Transoral and Transcervical Ultrasound of the Oropharynx (SPOT-US)

Oropharynx Cancer | Tonsil Cancer | Tonsil Hypertrophy | Base of the Tongue Tumor | Tonsil Ulcer | Tonsil Neoplasm | Tonsil Lymphoma | Base of Tongue Carcinoma

Denmark
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Oropharyngeal Squamous... and other conditions

United States, Puerto Rico, South Africa
Hookipa Biotech GmbH

Terminated

A Study HB-201 in Patients With Newly Diagnosed HPV16+ Oropharynx or Locally Advanced Cervical Cancer

HPV 16+ Confirmed Oropharynx Cancer and Cervical Cancer

United States

Clinical Trials on Oropharyngeal

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