Clinical Trials on Pneumonia, Viral in South Africa

Total 1189 results

Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia (EMPACTA)

COVID-19 Pneumonia

United States, Peru, Kenya, Mexico, Brazil, South Africa
National Institute of Health Research and Development...
Eijkman Institute for Molecular Biology; Indonesian Red Cross

Recruiting

Convalescent Plasma as Adjunct Therapy for COVID-19 (PlaSenTer)

COVID-19

Indonesia
Brown University
Rhode Island Hospital; University of Cape Town; Medical Research Council, South... and other collaborators

Active, not recruiting

Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa

Depression | Sexually Transmitted Diseases | Human Immunodeficiency Virus

South Africa
AstraZeneca

Completed

Phase II/III Study of AZD2816, for the Prevention of COVID-19 in Adults (AZD2816)

COVID-19 | SARS-CoV-2

United Kingdom, Brazil, South Africa, Poland
University of Sydney
Telethon Kids Institute; Bionet Co., Ltd; Technovalia; Institute for Clinical Pathology...

Completed

The Safety and Immunogenicity of a DNA-based Vaccine (COVIGEN) in Healthy Volunteers (COVALIA)

SARS-CoV2 COVID-19

Australia
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults (HVTN 097)

HIV Infection

South Africa
FHI 360
University of Cape Town; City University of New York, School of Public Health

Completed

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women

HIV

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
Australian National University
St Vincent's Hospital Melbourne; The George Institute; Royal North Shore Hospital and other collaborators

Withdrawn

Inhaled Heparin for Hospitalised Patients With Coronavirus Disease 2019 (COVID-19) (INHALE-HEP)

COVID-19

Australia
Sorrento Therapeutics, Inc.

Completed

Study to Assess the Safety, Tolerability and Pharmacokinetics of STI-1558 in Healthy Volunteers

COVID-19

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Females - A Sub-study of HPTN 084

HIV Infections

Zimbabwe, South Africa, Uganda
FHI 360
United States Agency for International Development (USAID); Makerere University and other collaborators

Completed

Interactions Between Antiretrovirals (ARVs) and Combined Oral Contraceptives (COCs)

HIV Infections | HIV/AIDS

South Africa, Uganda
Serum Institute of India Pvt. Ltd.
Bill and Melinda Gates Foundation

Not yet recruiting

Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 Years

Human Papillomavirus Infection

Kenya, Mozambique, South Africa
Larkin Community Hospital

Withdrawn

Phase 3 Open-Label Controlled Trial of Convalescent Plasma in Early COVID-19 Infection

Covid19

United States
Medical University of South Carolina

Completed

COVID Breath Test - Ancon

Covid19

United States
Larkin Community Hospital

Unknown

Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients

COVID-19

United States
DiaSorin Molecular LLC

Not yet recruiting

LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia

Coronavirus Disease 2019 | Influenza A | Respiratory Syncytial Virus (RSV) | Adenovirus | Influenza Type B | Enterovirus | Mycoplasma Pneumonia | Bordetella Parapertussis Infection | Chlamydia Pneumonia | Para Influenza | Bordetella Pertussis Infection, Respiratory

Australia
Public Health Service South Limburg
Maastricht University; National Institute for Public Health and the Environment... and other collaborators

Enrolling by invitation

Public Health Consequences of Covid-19

COVID-19

Netherlands
PTC Therapeutics

Terminated

A Study to Evaluate Efficacy and Safety of PTC299 (Emvododstat) in Hospitalized Participants With Coronavirus (COVID-19) (FITE19)

COVID-19 | Pneumonia | Coronavirus

Spain, United States, Australia, France, Brazil, Mexico, South Africa, Belgium, Colombia, Poland, Portugal
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
GlaxoSmithKline

Completed

Assess the Immune Response Following Primary Vaccination With GSK Biologicals' Tritanrix™-HepB/Hib-MenAC vs Tritanrix™-HepB/Hiberix™ Given at 6,10 & 14 Wks of Age to Infants Who Received Hepatitis B Vaccine at Birth

Diphtheria; Haemophilus Influenzae Type b; Hepatitis B; Tetanus; Whole Cell Pertussis

South Africa
Boehringer Ingelheim

Completed

A Study of Single Dose Nevirapine (NVP) Combined With Combivir® for the Prevention of Mother to Child Transmission (pMTCT) - Treatment Options Preservation Study (TOPS)

Acquired Immunodeficiency Syndrome

South Africa
Medical University of South Carolina
National Institutes of Health (NIH); National Institute of General Medical...

Completed

NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis

Covid19 | Coronavirus

United States
Brno University Hospital
European Society of Intensive Care Medicine; European Society of Anaesthesiology...

Completed

Corticosteroids in Severe COVID-19 (ASAP-ESICM/ESAIC Study) (ASAPESICMESAIC)

Severe COVID-19

Czechia
InflaRx GmbH

Completed

Randomized, Controlled Study of IFX-1 in Patients With Severe COVID-19 Pneumonia (PANAMO)

Severe COVID-19 Pneumonia

Belgium, Brazil, France, Germany, Mexico, Netherlands, Peru, Russian Federation, South Africa
Prisma Health-Upstate

Completed

COVID-19 on Placental Gene Expression and Pathology (PROSPER)

COVID-19 | SARS-CoV-2 Infection

United States
Massachusetts General Hospital
National Institute of Mental Health (NIMH); Match Research

Completed

Support for Perinatal Adherence and Depression (INSPireD)

Depression | Human Immunodeficiency Virus

United States, South Africa
Cynthia S Firnhaber
Merck Sharp & Dohme LLC

Completed

A Study to Examine the Human Papillomavirus Types Exposure in Women From Southern Africa and Brasil

HIV Infections | HIV

Botswana, Brazil, South Africa
Brno University Hospital
Masaryk University; Institute of Biostatistics and Analyses, Masaryk University... and other collaborators

Not yet recruiting

Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19 (OBAAMA-COV)

Obstetric Anesthesia Care

Czechia
Atea Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting

COVID-19

United States, Argentina, Belgium, Brazil, Egypt, Moldova, Republic of, Romania, South Africa, Spain, Ukraine
International Partnership for Microbicides, Inc.

Completed

A Safety and Tolerability Study of Dapivirine (TMC120) Vaginal Microbicide Gel

HIV Infections

Rwanda, South Africa, Tanzania
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

Evaluating the Safety and Immunogenicity of HIV-1 Vaccines Based on Chimpanzee Serotypes of Ad Expressing Clade C gp140 and a CH505TF gp120 Protein Boost in Healthy, HIV- Uninfected Adult Participants (HVTN139)

HIV Infections

South Africa
French National Agency for Research on AIDS and...
Gilead Sciences; European and Developing Countries Clinical Trials Partnership...

Completed

Tenofovir/Emtricitabine for PMTCT in Africa and Asia (ANRS 12109 TEmAA) (TEmAA)

HIV Infection | Pregnancy

Cambodia, South Africa, Côte D'Ivoire
Cadrock Pty. Ltd.
Centre for Digestive Diseases, Australia

Terminated

Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease (ACAC-CHD)

Coronary Heart Disease | Chlamydophila Pneumoniae Infections

Australia
Instituto de Atención Pediátrica
Pfizer; Ben-Gurion University of the Negev

Suspended

Costa Rica Epidemiological Study on S. Pneumoniae

Streptococcus Pneumoniae

Costa Rica
Public Health Foundation of India
University of Cape Town; Centre for Chronic Disease Control, India; World Heart...

Recruiting

WORLD HEART FEDERATION (WHF) COVID-19 and Cardiovascular Disease Survey (WHF)

Cardiovascular Diseases | COVID-19

Argentina, Bosnia and Herzegovina, Ghana, India, Iran, Islamic Republic of, Sudan, Colombia, Bangladesh, Japan, Kenya, Malaysia, Mexico, Nigeria, Pakistan, Portugal, South Africa, Zambia
Hasanuddin University
Chulalongkorn University

Completed

Post Coronavirus Disease (COVID-19) Syndrome Indonesian Population

Covid19

Indonesia
Dr Sze-Yuan Ooi
The University of New South Wales; The George Institute; South Eastern Sydney...

Unknown

Evaluation of a Remote Monitoring Smartphone Application and Care Model of COVID-19 Patients in the Community (ReCOVER) (ReCOVER)

COVID

Australia
University of California, San Francisco
Bill and Melinda Gates Foundation; Medical Research Council, South Africa; Ibis... and other collaborators

Withdrawn

Effectiveness of the Diaphragm for HIV Prevention

HIV Infection

South Africa, Zimbabwe
Sanford Health

Terminated

Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 Infection

COVID-19 | SARS-CoV 2

United States
Prisma Health-Upstate
Clemson University

Terminated

Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19

Covid19

United States
Clover Biopharmaceuticals AUS Pty Ltd
International Vaccine Institute; Coalition for Epidemic Preparedness Innovations

Completed

A Controlled Phase 2/3 Study of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Vaccine (SCB-2019) for the Prevention of COVID-19 (SCB-2019)

COVID-19

Colombia, Belgium, Brazil, Philippines, South Africa
TaiGen Biotechnology Co., Ltd.
Quintiles, Inc.

Completed

Safety and Efficacy Comparison of TG-873870(Nemonoxacin) to Levofloxacin in Community-Acquired Pneumonia

Community-Acquired Pneumonia

Taiwan, South Africa
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
Drugs for Neglected Diseases
University of Cape Town; Medecins Sans Frontieres, Netherlands; UBS Optimus Foundation and other collaborators

Completed

Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and TB

Acquired Immunodeficiency Syndrome | Tuberculosis

South Africa
ModernaTX, Inc.

Recruiting

A Study of an Investigational mRNA-1273.815 COVID-19 Vaccine in Previously Vaccinated Adults

SARS-CoV-2

Australia
Hoffmann-La Roche

Completed

A Study Evaluating Tocilizumab in Pediatric Patients Hospitalized With COVID-19

COVID-19

Spain, Germany, United States, Brazil, Italy, France, Greece, Croatia, Poland, South Africa, United Kingdom
Apogenix GmbH

Terminated

Asunercept for the Treatment of Patients With Moderate to Severe COVID-19 Disease (ASUCOV)

COVID-19

Spain, Germany, France, Italy, South Africa, India, Austria, Georgia, Poland
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute Ltd

Not yet recruiting

Covid-19 and Influenza Oral Vaccine Study

Influenza, Human | covid19 Infection

Australia
CONRAD
United States Agency for International Development (USAID); Bill and Melinda...

Terminated

Cellulose Sulfate and HIV Transmission Among Women

HIV Infection

India, South Africa, Benin, Uganda

Clinical Trials on Pneumonia, Viral in South Africa

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