Clinical Trials on Portal Hypertension

Total 15094 results

Air Force Military Medical University, China

Completed

The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPS

Decompensated Cirrhosis | Portal Hypertension | Bleeding Varices | Refractory Ascites

China
First Affiliated Hospital Xi'an Jiaotong University

Completed

Anticoagulation Therapy After Splenectomy in Cirrhosis Patient (ATASICP)

Liver Cirrhosis | Thrombosis | Portal Hypertension | Anticoagulant-induced Bleeding

China
University of California, San Francisco

Recruiting

A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients (WATCH)

Portal Hypertension | Cirrhosis, Liver | Ascites Hepatic

United States
Yanjing Gao
Shandong Provincial Hospital; Jinan Military General Hospital

Completed

The Treatment of Hepatocirrhosis and Portal Hypertension

Portal Hypertension | Hepatic Cirrhosis

China
Postgraduate Institute of Medical Education and...

Recruiting

Global Coagulation Assessment in Portal Vein Thrombosis and Budd-Chiari Syndrome (Liv-Thrombus)

Portal Vein Thrombosis | Anticoagulants and Bleeding Disorders | Hepatic Vein Thromboses | Hepatic Venous Outflow Obstruction | Portal Hypertension, Noncirrhotic | Portal Vein Occlusion | Portal Vein Embolism | JAK2 Mutation | CALR Gene Mutation | Prothrombin G20210A

India
Assiut University

Unknown

Hypersplenism in Patients With Liver Cirrhosis and Portal Hypertension

Hypersplenism
Hepatopancreatobiliary Surgery Institute of Gansu...
LanZhou University; Beijing 302 Hospital; Beijing Shijitan Hospital, Capital... and other collaborators

Completed

Timing of Endoscopy for Acute Variceal Bleeding in Patients With Cirrhosis

Portal Hypertension | Cirrhosis, Liver | Varice Bleed

China
Centre hospitalier de l'Université de Montréal...

Completed

Portal Pressure Effects of Phlebotomy Combined to Vasopressin Use in Cirrhotic Patients Undergoing Liver Transplantation (PORTAL)

Liver Transplantation | Portal Hypertension | Blood Loss, Surgical | Blood Transfusion

Canada
Shanghai Zhongshan Hospital

Unknown

Oxaliplatin-induced Portal Hypertension

Colorectal Cancer | Gastroesophageal Varices Hemorrhage | Received Oxaliplatin-based Chemotherapy

China
Aga Khan University
Ferozsons Laboratories Ltd.

Completed

Short Course Terlipressin for Control of Acute Variceal Bleeding

Hemorrhage | Portal Hypertension | Esophageal Varices

Pakistan
Shanghai Zhongshan Hospital

Completed

Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices

Portal Hypertension | Gastric Varices

China
Karolinska Institutet

Recruiting

Ultrasound Guided Microwave Ablation of Splenomegaly in Children

Portal Hypertension | Splenomegaly; Congestive, Chronic | Panhematopenia; Splenic

Sweden
Sun Yat-sen University
Second Affiliated Hospital of Guangzhou Medical University

Not yet recruiting

TIPS Combined With Microwave Ablation in HCC Patients With Refractory Ascites

Liver Diseases | Hepatocellular Carcinoma | Ascites | Portal Hypertension | Cirrhosis, Liver
Thomas Jefferson University
Children's Hospital of Philadelphia; National Institute of Diabetes and Digestive...

Recruiting

SHAPE of Portal Hypertension in Children

Hypertension, Portal

United States
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Transfusion Requirements in Gastrointestinal (GI) Bleeding

Cirrhosis | Portal Hypertension | Upper Gastrointestinal Bleeding

Spain
Mayo Clinic

Completed

A Prospective Evaluation of Computerized Tomographic(CT) Scanning as a Screening Modality for Esophageal Varices

Portal Hypertension | Esophageal Varices | Gastric Varices
Nanfang Hospital of Southern Medical University
Beijing 302 Hospital; Beijing Shijitan Hospital, Capital Medical University

Completed

Virtual Hepatic Venous Pressure Gradient (vHVPG) With CT Angiography (CHESS1601) (vHVPG)

Hypertension, Portal

China
Nanfang Hospital of Southern Medical University
Beijing Ditan Hospital; Beijing 302 Hospital; First Affiliated Hospital, Sun... and other collaborators

Withdrawn

Virtual Imaging-based Early Portal Pressure Gradient (vePPG) (CHESS1702) (vePPG)

Hypertension, Portal

China
University of Nottingham
Nottingham University Hospitals NHS Trust; University Hospital Birmingham NHS... and other collaborators

Recruiting

Can MRI Evaluate Beta-blocker Response in Portal Hypertension? (B-SMaRT)

Liver Cirrhosis | Portal Hypertension | Varix, Esophageal

United Kingdom
Pomeranian Medical University Szczecin

Completed

Evaluation of Probiotics in the Treatment of Portal Hypertension

Liver Cirrhosis | Portal Hypertension | Encephalopathy

Poland
King Faisal Specialist Hospital & Research Center
Federico II University of Naples, Department of Clinical Medicine and Surgery... and other collaborators

Unknown

Somatostatin in Living Donor Liver Transplantation

Portal Hypertension | End Stage Liver DIsease
University Hospital, Bonn

Completed

Myocardial Fibrosis and Inflammation in Liver Cirrhosis

Cardiomyopathies | Portal Hypertension | Cirrhosis, Liver

Germany
General Hospital of Shenyang Military Region

Not yet recruiting

Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver Cirrhosis

Liver Cirrhosis | Bleeding | Esophageal and Gastric Varices | Portal Hypertension | Variceal Hemorrhage
Meridian Bioscience, Inc.

Completed

MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy

Bleeding | Cirrhosis | Portal Hypertension | Chronic Liver Disease | Esophageal Varices

Israel
University of Padova

Unknown

Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varices (ERASE)

Liver Cirrhosis | Portal Hypertension

Italy
Universidade Federal do Rio de Janeiro
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Simvastatin Effect on Portal Hypertension

Liver Cirrhosis | Portal Hypertension | Esophageal Varices

Brazil
Mayo Clinic

Completed

Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis

Cirrhosis | Portal Hypertension | Esophageal Varices
University of Alexandria

Completed

Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope

Portal Hypertension | Hematemesis

Egypt
Centre Hospitalier Universitaire de Nice

Recruiting

Portal Hypetension and Bariatric Surgery (BARIAPORTAL) (BARIAPORTAL)

Obesity, Morbid | Bariatric Surgery Candidate | Portal Hypertension

France
Tang-Du Hospital

Completed

Liver Resection for Patients With Hepatocellular Carcinoma and Clinically Significant Portal Hypertension

Hepatic Carcinoma

China
Zhongda Hospital

Recruiting

Impact of Clinical Evident Portal Hypertension on HCC With TACE (CHANCE-CHESS 2301)

Hepatocellular Carcinoma | Portal Hypertension

China
Zhongda Hospital

Recruiting

CT-based HVPG Assessment for Predicting the Prognosis of HCC With TACE (CHANCE-CHESS 2302)

Hepatocellular Carcinoma | Portal Hypertension

China
Histogen

Completed

Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension (ENCORE-PH)

Cirrhosis | Portal Hypertension | Non-alcoholic Steatohepatitis

United States, Germany, Spain
Institute of Liver and Biliary Sciences, India

Completed

To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices.

Cirrhosis With Esophageal Varices

India
National Institute of Diabetes and Digestive and...
Yale University

Completed

Prevention of Esophageal Varices by Beta-Adrenergic Blockers

Liver Cirrhosis | Esophageal and Gastric Varices | Portal Hypertension

United States, Spain, United Kingdom
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Completed

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14

Cirrhosis | Portal Hypertension | NASH - Nonalcoholic Steatohepatitis

France
Nanfang Hospital of Southern Medical University

Unknown

Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With Cirrhosis

Portal Hypertension | Gastroesophageal Varices

China
Nanfang Hospital, Southern Medical University

Recruiting

SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury

End Stage Liver Disease | Portal Hypertension | Jaundice | Liver Dysfunction

China
Beijing Friendship Hospital

Active, not recruiting

Carvedilol for Prevention of Esophageal Varices Progression (Carvedilol)

Portal Hypertension | Cirrhosis, Liver

China
ShuGuang Hospital
Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Public Health Clinical... and other collaborators

Unknown

Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir

Portal Hypertension

China
Aga Khan University

Completed

The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed

Cirrhosis | Portal Hypertension | Melena | Hematemesis

Pakistan
Institut d'Investigacions Biomèdiques August Pi...
Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital; Hospital Universitario... and other collaborators

Unknown

TIPS in Fundal Variceal Bleeding (the TFB Study) (TFB)

Bleeding Gastric Varices | Portal Hypertension

Spain
Fei Gao

Not yet recruiting

TIPS Plus Cadonilimab in Advanced HCC With Tumor Thrombosis-associated Portal Hypertension:a Prospective, Single-arm, Phase II Study

Hepatocellular Carcinoma

China
Federal University of Minas Gerais

Unknown

Evaluation of Gastroesophageal Varices by Transnasal Endoscopy.

Liver Cirrhosis | Esophageal Varices | Gastric Varices | Hypertension Portal
Debiovision

Completed

Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleeding

Portal Hypertension | Esophageal Varices | Gastric Varices | Esophageal Bleeding

United States
West China Hospital
Beijing YouAn Hospital; Guangzhou First People's Hospital; Renmin Hospital of... and other collaborators

Not yet recruiting

Preemptive TIPS for Gastric Variceal Bleeding in Patients With Cirrhosis

Portal Hypertension | Portosystemic Shunt | Gastric Varices Bleeding
Nanfang Hospital of Southern Medical University
Beijing Friendship Hospital; Beijing YouAn Hospital; Beijing 302 Hospital; Shandong... and other collaborators

Recruiting

Serum Biomarkers for Portal Hypertension in Cirrhosis (Pan-CHESS1802)

Hypertension, Portal

China
Nanfang Hospital of Southern Medical University
LanZhou University; Beijing 302 Hospital; Shandong Provincial Hospital; Zhongda... and other collaborators

Completed

MR-based Models for Clinically Significant Portal Hypertension in Cirrhosis (CHESS1802)

Hypertension, Portal

China, Turkey
Nanfang Hospital of Southern Medical University
Beijing YouAn Hospital; Beijing 302 Hospital; Beijing Shijitan Hospital, Capital... and other collaborators

Completed

Radiomics Signature of Hepatic Venous Pressure Gradient (rHVPG) With CT Angiography (CHESS1701) (rHVPG)

Hypertension, Portal

China
Boehringer Ingelheim

Active, not recruiting

A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Live

Hypertension, Portal

Spain, Denmark, United Kingdom, Singapore, Germany, Italy, Austria, Canada, Croatia, China, Taiwan, Netherlands, Belgium, United States, Korea, Republic of, Japan, Argentina, France, Switzerland, Portugal, Israel, Romania

Clinical Trials on Portal Hypertension

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CROs in Mongolia

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