Clinical Trials on Postpancreatectomy Hemorrhage in South Africa

Total 564 results

University of Pretoria

Completed

A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

Prevention of Post Partum Haemorrhage

South Africa
University of Birmingham
King's College London; University College, London; University of Nairobi; World... and other collaborators

Completed

A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth (E-MOTIVE)

Post-Partum Haemorrhage

South Africa, Kenya, Tanzania, Nigeria
The George Institute
National Health and Medical Research Council, Australia

Completed

Head Position in Stroke Trial (HeadPoST) (HeadPoST)

Ischemic Stroke | Intracerebral Haemorrhage

Australia
Neuroscience Trials Australia

Completed

STOP-AUST: The Spot Sign and Tranexamic Acid On Preventing ICH Growth - AUStralasia Trial (STOP-AUST)

Stroke | Intracerebral Haemorrhage

Australia, Finland
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Completed

STOP-MSU: Stopping Haemorrhage With Tranexamic Acid for Hyperacute Onset Presentation Including Mobile Stroke Units

Intracerebral Haemorrhage

Australia, Finland, Taiwan, New Zealand, Vietnam
Gynuity Health Projects
University of Witwatersrand, South Africa; Effective Care Research Unit; Family...

Completed

Misoprostol for Preventing Postpartum Hemorrhage

Postpartum Hemorrhage

Uganda, Nigeria, South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Investigating the Tolerability and Feasibility of Transcutaneous Vagus Nerve Stimulation Following Aneurysmal Subarachnoid Haemorrhage (tVNS in aSAH)

Subarachnoid Haemorrhage From Cerebral Aneurism Rupture

United Kingdom
University of Cape Town

Completed

VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax

Empyema | Haemothorax

South Africa
Sangart

Completed

Phase IIa Study of MP4OX in Traumatic Hemorrhagic Shock Patients

Shock, Hemorrhagic | Acidosis, Lactic | Shock, Traumatic

France, United Kingdom, South Africa, Germany
University of Stellenbosch

Unknown

The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases

Haemoptysis

South Africa
The George Institute
University of Sydney

Terminated

Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study (TRIDENT COG)

Hypertension | Cerebral Small Vessel Diseases | Dementia, Vascular | Stroke Hemorrhagic | Cognitive Decline | Intracerebral Hemorrhage

Australia, Netherlands
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa
Novo Nordisk A/S

Completed

Recombinant Factor VIIa in Acute Intracerebral Haemorrhage (FAST)

Acquired Bleeding Disorder | Intracerebral Haemorrhage

United States, Spain, Germany, Sweden, Netherlands, Austria, Belgium, Singapore, Taiwan, Israel, Italy, Denmark, Australia, Thailand, France, Norway, Croatia, Hong Kong, China, Canada, Switzerland, Brazil, Finland
The George Institute
The University of New South Wales

Recruiting

Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT)

Hypertension | Intracerebral Haemorrhage (ICH)

United Kingdom, Australia, Singapore, Georgia, Netherlands, Nigeria, Sri Lanka, Switzerland, Brazil, Malaysia, Taiwan, Vietnam
University of Melbourne

Recruiting

Ultra-Early, Minimally inVAsive intraCerebral Haemorrhage evacUATion Versus Standard trEatment (EVACUATE)

Stroke | Intra Cerebral Hemorrhage

Australia
Joseph Broderick, MD
Novo Nordisk A/S; National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial (FASTEST)

Intracerebral Hemorrhage

United States, Canada, Germany, Japan, Spain, United Kingdom
Viz.ai, Inc.

Enrolling by invitation

ADVANCE- Automated Detection and Volumetric Assessment of ICH

Intracerebral Hemorrhage

United States
The George Institute
National Health and Medical Research Council, Australia

Completed

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

Intracranial Hemorrhages | Cerebral Hemorrhage | CVA (Cerebrovascular Accident)

Australia, New Zealand, China
AegisCN LLC
Duke Clinical Research Institute; PharPoint Research, Inc.

Completed

A Proof of Concept Study to Evaluate CN-105 in ICH Patients (CATCH)

Intracerebral Hemorrhage

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Activated Recombinant Human Factor VII in Severely Injured Trauma Patients

Trauma | Acquired Bleeding Disorder

Germany, Austria, Israel, France, Canada, Singapore, South Africa, Australia, United Kingdom
Duke University
Daiichi Sankyo, Inc.; Medtronic; Chiesi Farmaceutici S.p.A.

Completed

IMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care

Intracranial Hemorrhages | Subarachnoid Hemorrhage | Acute Stroke

United States
Faculty of Medicine

Completed

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Uterine Hemorrhage | Adverse Effect of Oxytocic Drugs | Inappropriate Dose of Drug Administered

Uganda
Integra LifeSciences Corporation
Icahn School of Medicine at Mount Sinai; Oculus Imaging LLC

Recruiting

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation (MIRROR)

Supratentorial Hemorrhage

United States
Sangart

Withdrawn

Phase 2c Dose Comparison Study of MP4OX in Trauma

Trauma | Hemorrhagic Shock | Lactic Acidosis

New Zealand, United Kingdom, Israel, France, Switzerland, Australia, Belgium, Brazil, Germany, Norway, South Africa
Baylor College of Medicine
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Treatment of Subarachnoid Hemorrhage With Human Albumin

Subarachnoid Hemorrhage

United States, Canada
J. Mocco
University at Buffalo; MOUNT SINAI HOSPITAL

Completed

INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage

Intracranial Hemorrhage

United States
J. Mocco
University at Buffalo; MOUNT SINAI HOSPITAL

Completed

INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage

Intracranial Hemorrhage

United States
Cerebrotech Medical Systems, Inc.

Completed

Volumetric Integral Phase-shift Spectroscopy for Noninvasive Detection of Hemispheric Bioimpedance Asymmetry in Acute Brain Pathology (VITAL)

Stroke | Hemorrhage | Ischemic Stroke | Cerebral Infarction | Subarachnoid Hemorrhage | Cerebral Hemorrhage | Stroke, Acute | Intracerebral Hemorrhage | Cerebral Stroke | Clot (Blood); Brain | Intracerebral Injury

United States
Gold Coast Hospital and Health Service
Prince of Wales Hospital, Sydney; Sir Charles Gairdner Hospital; Liverpool Hospital...

Unknown

Safety and Clinical Effectiveness of Pipeline™ Shield Devices for Intracranial Aneurysms (SCOPE-AUS)

Subarachnoid Hemorrhage | Cerebral Hemorrhage | Neurologic Disorder | Stroke, Acute | Cerebral Aneurysm | Intracranial Aneurysm | Cerebral Stroke

Australia
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

SAHaRA: A Randomized Controlled Trial

Subarachnoid Hemorrhage, Aneurysmal

United States, Australia, Canada
University of Minnesota
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Antihypertensive Treatment in Acute Cerebral Hemorrhage (ATACH)

Stroke | Hypertension | Intracerebral Hemorrhage

United States
Seoul National University Hospital
Asan Medical Center; Johannes Gutenberg University Mainz; Gyeongsang National... and other collaborators

Active, not recruiting

CoHOrt of Cerebral CavernOus maLformATion: multicEnter Prospective Observational Study (CHOCOOATE)

Intracerebral Hemorrhage | Cerebral Cavernous Malformation

Korea, Republic of
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

The Spot Sign for Predicting and Treating ICH Growth Study (STOP-IT)

Intracerebral Hemorrhage

United States, Canada
Penumbra Inc.

Active, not recruiting

MIND: Artemis in the Removal of Intracerebral Hemorrhage

Cerebral Hemorrhage | Intracerebral Hemorrhage | Brain Hemorrhage | Cerebral Parenchymal Hemorrhage

United States, Germany, Canada, Austria
University of Manchester
Northern Care Alliance NHS Foundation Trust; National Institute for Health... and other collaborators

Active, not recruiting

SC IL-1Ra in SAH - Phase III Trial (SCIL) (SCIL)

Subarachnoid Hemorrhage

United Kingdom
Johns Hopkins University
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,... and other collaborators

Completed

Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III (MISTIE-III)

Intracerebral Hemorrhage

United States, Australia, Germany, China, Spain, Canada, Israel, Hungary, United Kingdom
Edge Therapeutics Inc

Terminated

Study of EG-1962 Compared to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage (NEWTON2)

Subarachnoid Hemorrhage, Aneurysmal

United States, Canada, Australia, Hong Kong, Israel, New Zealand, Singapore, Finland, Czechia, Austria, Germany
Australian and New Zealand Intensive Care Research...
Australian and New Zealand Intensive Care Society Clinical Trials Group; Australasian... and other collaborators

Recruiting

Fibrinogen Early In Severe Trauma StudY II (FEISTY II)

Trauma | Coagulopathy | Haemorrhagic Shock

Australia
Johns Hopkins University
Genentech, Inc.; FDA Office of Orphan Products Development

Completed

Clinical Trial on Treatment of Intraventricular Hemorrhage (CLEAR IVH)

Intraventricular Hemorrhage

United States, Germany, Canada, United Kingdom
The Medicines Company

Completed

Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE) (ACCELERATE)

Hypertension | Hemorrhage

United States, Germany
Beth Israel Deaconess Medical Center
Medical University of South Carolina; Johns Hopkins University; Massachusetts... and other collaborators

Completed

Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial

Intracerebral Hemorrhage

United States, Canada
C. R. Bard
Boston University; Yale University

Terminated

Impact of Fever Prevention in Brain Injured Patients (INTREPID)

Ischemic Stroke | Fever | Subarachnoid Hemorrhage | Intracerebral Hemorrhage

Korea, Republic of, United States, Germany, Switzerland, Austria, Australia
Beth Israel Deaconess Medical Center
Medical University of South Carolina; Johns Hopkins University; Massachusetts... and other collaborators

Terminated

High-Dose Deferoxamine in Intracerebral Hemorrhage (HI-DEF)

Intracerebral Hemorrhage

United States, Canada
Daniel Hanley
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,... and other collaborators

Completed

Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation (MISTIE)

Intracerebral Hemorrhage

United States, Germany, United Kingdom, Canada
The George Institute
University of Sydney

Terminated

Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial Magnetic Resonance Imaging Sub-study (TRIDENT-MRI)

Stroke | Hypertension | Cerebral Small Vessel Diseases | Vascular Dementia | Intracerebral Hemorrhage

Australia
Bayer

Completed

MiCo - Mirena or Conventional Medical Treatment for Menorrhagia

Idiopathic Menorrhagia

Croatia, South Africa, Colombia, Czech Republic, Jordan, Lebanon, Macedonia, The Former Yugoslav Republic of, Moldova, Republic of, Romania, Ukraine, Venezuela, Bosnia and Herzegovina, Syrian Arab Republic, Albania
Sangart

Completed

Phase IIb Study of MP4OX in Traumatic Hemorrhagic Shock Patients

Shock, Hemorrhagic | Acidosis, Lactic | Shock, Traumatic

Norway, Singapore, Israel, France, United Kingdom, Germany, Switzerland, Australia, Brazil, South Africa, New Zealand, Colombia, Austria, Spain
Bayer

Completed

Study of FVIIa Variant BAY86-6150 (B0189) in Subjects With Moderate or Severe Hemophilia Types A or B With or Without Inhibitors (MATCHBOX)

Hemophilia A | Hemophilia B

South Africa, Poland, United Kingdom
Novo Nordisk A/S

Completed

Epidemiological Study on Haemophilia Care and Orthopaedic Status in Developing Countries (HAEMOcare)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

India, Morocco, South Africa, Oman
Baxalta now part of Shire

Terminated

Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A

Hemophilia A

United States, South Africa, United Kingdom

Clinical Trials on Postpancreatectomy Hemorrhage in South Africa

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