Clinical Trials on Precancerous Conditions in South Africa

Total 20315 results

University of Witwatersrand, South Africa

Unknown

A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women

Cervical Dysplasia

South Africa
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
Antiva Biosciences

Recruiting

A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Australia, South Africa
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS

Cryptococcal Meningitis

South Africa
Bial - Portela C S.A.

Completed

An Open-label, Single-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Epilepsy

South Africa
University of Exeter
University College, London; Medical Research Council, South Africa

Completed

Stepping Stones and Creating Futures Plus Pilot

Intimate Partner Violence | Poverty

South Africa
FHI 360
United States Agency for International Development (USAID); University of Witwatersrand...

Completed

Assessing Preference for 3 Female Condoms: A Comparative Evaluation of the PATH Woman's Condom, FC2 and the Reddy 6

Contraception

South Africa
GlaxoSmithKline

Completed

Study to Determine the Bioequivalence of Two Fixed Dose Combination (FDC) Tablet Formulations of Amlodipine and Losartan FDC5/50 and FDC5/100 Under Fasting Conditions

Hypertension

South Africa
University of Witwatersrand, South Africa

Completed

Comparison Of Trabeculectomy Versus The Ex-PRESS Miniature Glaucoma Device In The Same Patient: A Prospective Randomized Study (XVT-USF)

Glaucoma

South Africa
Bial - Portela C S.A.

Completed

An Open-label, Multiple-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Epilepsy

South Africa
Massachusetts General Hospital
Boston University; University of Cape Town

Recruiting

South Africa Smoking Cessation and Engagement in HIV/TB Care Care

HIV Infections | Smoking Cessation | Tuberculosis

South Africa
Centers for Disease Control and Prevention
Johns Hopkins University; Sanofi; University of Stellenbosch; University of Cape... and other collaborators

Recruiting

Tuberculosis Clinical Trials Consortium Study 35

Latent Tuberculosis

South Africa
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Human Sciences... and other collaborators

Active, not recruiting

Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa

HIV/AIDS | Alcohol Abuse

South Africa
Penn State University
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Drug and HIV Prevention in South Africa

Substance-Related Disorders | Sexually Transmitted Diseases

South Africa
The Wistar Institute

Completed

Anti-HIV Treatment Interruptions in HIV Infected Adults in South Africa

HIV Infections

South Africa
Johns Hopkins Bloomberg School of Public Health
United States Agency for International Development (USAID); University of KwaZulu and other collaborators

Completed

Safety and Efficacy of Zinc Supplementation in HIV-1-Infected Children in South Africa

HIV Infections

South Africa
AstraZeneca

Completed

Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Undertreatment of Hypercholesterolaemia

South Africa
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa
Eunice Kennedy Shriver National Institute of Child...
Columbia University; University of Witwatersrand, South Africa

Unknown

Pediatric Nevirapine Resistance Study

HIV Infections | AIDS

South Africa
International Partnership for Microbicides, Inc.

Active, not recruiting

Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008

HIV Infections

South Africa
Population Council
Medical Research Council; Centers for Disease Control and Prevention

Completed

Safety and Acceptability of Carraguard® in HIV Positive Women and Men

HIV Infections

South Africa
Johns Hopkins University

Completed

Statin Adjunctive Therapy for TB (StAT-TB)

Tuberculosis

South Africa
Boston University
Clinton Health Access Initiative, Nigeria; Health Economics and Epidemiology...

Recruiting

DSD Models at South Africa Sentinel Sites (SENTINEL 2)

HIV

South Africa
Cryonove Pharma
Dermatech

Not yet recruiting

Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face (CS5_10)

Lentigo | Solar Lentigo | Post Inflammatory Hyperpigmentation

South Africa
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Recruiting

Support for Adolescents Living With HIV in South Africa (InTSHA VIP)

HIV | Human Immunodeficiency Virus

South Africa
Johns Hopkins Bloomberg School of Public Health
University of California, San Francisco; University of Toronto; National Institute... and other collaborators

Completed

HIV Treatment Retention Interventions for Women Living With HIV (Siyaphambili Study)

HIV-1 Virologic Response

South Africa
International AIDS Vaccine Initiative
Biofabri, S.L; South African Tuberculosis Vaccine Initiative; Universidad de...

Completed

MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africa (A-050)

Tuberculosis

South Africa
Medical College of Wisconsin
National Institute of Mental Health (NIMH)

Completed

Experimental Analysis of HIV Risk Assessment Reactivity in South African Clinics

HIV Prevention and Assessment Reactivity

South Africa
Pfizer

Completed

Study Investigating the Safety and Tolerability of Multiple Doses of PF-02545920 in Subjects With Schizophrenia

Schizophrenia | Schizo-affective Disorder

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Tuberculosis Prevention for HIV Infected Adults

HIV Infections | Tuberculosis

South Africa
University of Witwatersrand, South Africa

Completed

Epidemiology of Congenital Cytomegalovirus in a High HIV Prevalence Setting, South Africa

Neurodevelopmental Disorders | Hearing Loss | Immunogenicity | Stillbirth | Neonatal Death | Cytomegalovirus Congenital

South Africa
MedImmune LLC
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Trial To Assess Safety And Efficacy Of Influenza Virus Vaccine, Trivalent, Types A & B, Live Cold-Adapted (CAIV-T) In Adults Aged 60 Years And Older

Influenza

South Africa
Alvotech Swiss AG

Active, not recruiting

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase Study Conducted in Healthy Volunteers

South Africa
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Completed

InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media (InTSHA)

HIV-1-infection | Adolescent Behavior

South Africa
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Recruiting

Gathering Records to Evaluate Antiretroviral Treatment-South Africa (GREAT)

HIV

South Africa
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
Aeras
Statens Serum Institut

Completed

Safety and Immunogenicity Study of AERAS-456 Vaccine for Tuberculosis

Latent Tuberculosis | Latent Tuberculosis Bacteriology and Histology Unknown

South Africa
RTI International
Setshaba Research Centre

Completed

The PrEPARE Project: Prevention, Empowering, and Protecting Young Women in South Africa

HIV Prevention

South Africa
GlaxoSmithKline

Completed

Feasibility Study for Identifying Anti Capsular Antibody Protection Against Invasive Group B Streptococcus (GBS) Disease in Newborns of 0-6 Days Age (Early Onset Disease [EOD]) as Well as Among Infants of 7-90 Days Age (Late Onset Disease [LOD])

Streptococcus Agalactiae

South Africa
Smith & Nephew, Inc.

Completed

Treatment of Wounds With a New Adhesive Foam Dressing

Wounds and Injuries | Burns

South Africa
Sanofi

Completed

Efficacy and Safety Study of New Ambroxol Hardboiled Lozenges in Acute Pharyngitis (DELICIOUS)

Pharyngitis

South Africa
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

COVID-19 Treatment in South Africa

COVID-19

South Africa
ImmunityBio, Inc.

Active, not recruiting

COVID-19 Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenoviral Platform in Healthy South African Adults

Covid19

South Africa
Gilead Sciences

Active, not recruiting

Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women

HIV-1-infection

South Africa
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

Effects of Cash Transfer for the Prevention of HIV in Young South African Women

HIV

South Africa
RTI International
United States Agency for International Development (USAID); FHI 360; Wits Reproductive...

Completed

CHARISMA Expansion Study (CHARISMA)

Relationship Dynamics | Pre-exposure Prophylaxis (PrEP) Adherence

South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between GSK3542503 Hydrochlorothiazide + Amiloride Hydrochloride 50 mg: 5 mg Tablets and Reference Product in Healthy Adult Participants Under Fasting Conditions

Hypertension

South Africa

Clinical Trials on Precancerous Conditions in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Venezuela

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations