Clinical Trials on Primary Myelofibrosis in Czechia

Total 848 results

AbbVie

Active, not recruiting

Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis (TRANSFORM-2)

Myelofibrosis (MF)

United States, Australia, Austria, Belgium, Bulgaria, Canada, Croatia, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, New Zealand, Poland, Puerto Rico, Russian Federation, Serbia, South... and more
Karyopharm Therapeutics Inc

Recruiting

Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis (SENTRY)

Myelofibrosis

United States, Korea, Republic of, Belgium, Italy, Spain, France, United Kingdom, Israel, Czechia, Taiwan, Canada, Germany, Romania, Bulgaria, Poland, Denmark
Celgene

Recruiting

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions (INDEPENDENCE)

Primary Myelofibrosis | Myeloproliferative Disorders | Anemia | Myelofibrosis | Post-Polycythemia Vera Myelofibrosis

France, Belgium, Spain, Australia, Canada, United States, Korea, Republic of, Romania, Japan, Israel, Italy, Austria, China, Czechia, Germany, Greece, Ireland, Poland, United Kingdom, Hong Kong, Hungary, Lebanon, Argentina, Chile, Colombia and more
Stimvia s.r.o.

Completed

Open Label Study to Evaluate the Efficacy of the Home Based Electrical Transcutaneous URIS I in the Treatment of Overactive Bladder (OAB).

Overactive Bladder (OAB) | Failed Any OAB Pharmacotherapy

Czechia
Sierra Oncology, Inc.

Completed

Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis (Simplify 1)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, France, Germany, Spain, Israel, Bulgaria, Romania, Japan, Taiwan, Korea, Republic of, Australia, Belgium, Canada, Netherlands, Singapore, Poland, Hungary, Denmark, Sweden, United Kingdom, Czechia, Austria
Constellation Pharmaceuticals

Active, not recruiting

Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2) (MANIFEST-2)

Primary Myelofibrosis | Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

Korea, Republic of, Spain, United States, Canada, Taiwan, Czechia, United Kingdom, Australia, Italy, Belgium, Germany, France, Israel, Greece, Malaysia, Netherlands, Austria, Turkey, Poland, Thailand, Hong Kong, Hungary
CTI BioPharma

Terminated

Pacritinib Versus Best Available Therapy to Treat Myelofibrosis

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States, Australia, Belgium, Czechia, France, Germany, Hungary, Italy, Netherlands, New Zealand, Russian Federation, United Kingdom
Sierra Oncology LLC - a GSK company

Completed

A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

Korea, Republic of, Canada, Hungary, Israel, Spain, United States, Australia, Taiwan, Singapore, Germany, Italy, France, Belgium, New Zealand, Austria, United Kingdom, Denmark, Bulgaria, Poland, Czechia, Romania, Sweden
Charles University, Czech Republic

Completed

High Flow Nasal Cannula Is Appropriate Alternative for Stabilization of Very Premature Infants: A Prospective Observational Study (SIMPLSAFE)

High Flow Nasal Cannula for the Stabilization of Very Preterm Infants

Czechia
Masaryk Memorial Cancer Institute
Masaryk University

Recruiting

Prostate Cancer Screening With Abbreviated MRI Protocol (ProstaPilot)

Prostate Cancer

Czechia
University Hospital Ostrava

Recruiting

Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients

Arterial Hypertension

Czechia
CTI BioPharma
PSI CRO

Recruiting

A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis (PACIFICA)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

Korea, Republic of, Spain, Canada, Czechia, United States, Australia, France, Hungary, United Kingdom, Romania, Belarus, Bulgaria, Georgia, Germany, Israel, Italy, Poland, Russian Federation, Serbia, Ukraine, Bosnia and Herzegovina and more
Novartis Pharmaceuticals

Completed

INC424 for Patients With Primary Myelofibrosis, Post Polycythemia Myelofibrosis or Post-essential Thrombocythemia Myelofibrosis. (JUMP)

Myelofibrosis

Belgium, Colombia, Canada, Italy, Spain, Austria, Germany, Czechia, Thailand, Hungary, Greece, Argentina, Brazil, Israel, Russian Federation, Mexico, Portugal, South Africa, Tunisia, Slovakia, Saudi Arabia, Poland, Algeria, Ireland, Mor...
CTI BioPharma

Terminated

Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and Thrombocytopenia (PAC326)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States, Canada, France, United Kingdom, Australia, Belgium, Germany, New Zealand, Netherlands, Russian Federation, Hungary, Czechia
University Hospital Ostrava

Completed

Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

Septic Shock | Respiratory Insufficiency | Hypoxemia | Chronic Obstructive Pulmonary Disease Exacerbation | Lung Ventilator | Hyperhydration | Respiratory Distress Syndrome, Acute

Czechia
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Active, not recruiting

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM2)

Primary Myelofibrosis | Myelofibrosis | Post-Polycythemia Vera

Australia, Austria, Belgium, China, Czechia, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Ireland, United Kingdom
Kartos Therapeutics, Inc.

Recruiting

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment (BOREAS)

Primary Myelofibrosis (PMF) | Post-Polycythemia Vera MF (Post-PV-MF) | Post-Essential Thrombocythemia MF (Post-ET-MF)

United States, Korea, Republic of, Germany, Australia, Hungary, France, Spain, Italy, Taiwan, Thailand, Brazil, Poland, Turkey, Israel, Portugal, Romania, Argentina, Bulgaria, Canada, Croatia, Czechia, Lithuania, Mexico, Philippines, United... and more
Value Outcomes Ltd.
Matuzalem.com-cz, s.r.o.

Completed

Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment (MAT072017)

Vaginosis, Bacterial | Vaginal Flora Imbalance

Czechia
Thomayer University Hospital
Czech Academy of Sciences

Recruiting

Bacterial Metallophores in the Diagnosis of Acute Pyelonephritis

Acute Pyelonephritis | Complicated Urinary Tract Infection

Czechia
University Hospital, Motol

Completed

Primary Hemostasis Pathology in Patients on ECMO During Lung Transplantation

ECMO Primary Hemostasis Pathology

Czechia
Hamlet Pharma AB

Recruiting

A First-in-Human Study of alpha1H in Patients With Non-muscle Invasive Bladder Cancer

Non-muscle Invasive Bladder Cancer

Czechia
University Hospital Olomouc
Palacky University

Recruiting

Effect of Beta-alanine and Pelvic Floor Muscle Training on Urinary Incontinence After Radical Prostatectomy (BELA) (BELA)

Urinary Incontinence | Prostate Cancer | Radical Prostatectomy | Pelvic Floor Muscle Training | Beta-Alanine

Czechia
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Myopowers Medical Technologies France SAS

Completed

ARTUS MONO Artificial Urinary Sphincter

Urinary Incontinence,Stress

France, Czechia
Klaudia Michalcinova

Recruiting

The Effect of Physiotherapy on Treatment Success by Assisted Reproductive Technologies

Infertility

Czechia
Charles University, Czech Republic

Not yet recruiting

Endometrioma Treatment and Ovarian Function (EnTOF)

Endometrioma

Czechia
University Hospital, Motol

Terminated

Point-of-care Management of Coagulopathy in Lung Transplantation

Lung Transplantation

Czechia
LinkoCare Life Sciences AB

Active, not recruiting

Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for Correction of Presbyopia. (CorVision)

Presbyopia

Czechia
Aesculap AG

Recruiting

Ceramic Modular Dual Mobility in Primary Total Hip Arthroplasty (THA) (CeMoD-prime)

Coxarthrosis; Primary

Czechia
Fresenius Kabi
EastHORN Clinical Services in CEE; MLM Medical Labs GmbH; ALS Czech Republic,... and other collaborators

Completed

Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients (CKD)

Renal Insufficiency, Chronic

Czechia
Institute for Clinical and Experimental Medicine
Czech Academy of Sciences

Recruiting

Gluten-free Diet in PSC and IBD

Biliary Tract Diseases | Ulcerative Colitis | Primary Sclerosing Cholangitis | Intestinal Disease | Biliary Disease Tract

Czechia
University Hospital Ostrava

Completed

Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid Surgery

Primary Hyperparathyroidism | Parathyroid Diseases | Thyroid Disease | Parathyroid Adenoma

Czechia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Charles University, Czech Republic
University Hospital Pilsen

Completed

SLNM in Endometrial Cancer Combined With OSNA (SLNM/OSNA)

Endometrial Cancer

Czechia
Institute for the Care of Mother and Child, Prague...
University Hospital Ostrava

Recruiting

Laparoscopic Therapy of Endometrioma: Sclerotherapy vs Cystectomy in Patients With Unfinished Reproductive Plans

Endometriosis | Endometrioma

Czechia
SOTIO a.s.

Terminated

A Phase I/II, Safety Clinical Trial of DCVAC/PCa and ONCOS-102 in Men With Metastatic Castration-resistant Prostate Cancer

Castration-resistant Prostate Cancer

Czechia
Vensica Therapeutics Ltd.

Completed

Vibe First In Human Study for the Assessment of Safety and Initial Performance of the Vibe Delivery System in Subjects With Idiopathic Overactive Bladder

Overactive Bladder

Czechia, Portugal
Myopowers Medical Technologies France SAS
EVAMED; Affluent Medical

Not yet recruiting

Safety and Clinical Performance Study of the ARTUS® Artificial Urinary Sphincter (AUS) (DRY)

Stress Urinary Incontinence

Spain, Czechia
Kamil Novobílský

Completed

Verification of the Safety of Early Discharge in Patients After Acute ST-segment Myocardial Infarction

Coronary Artery Disease | Primary Percutaneous Coronary Intervention | Early Discharge | Acute Myocardial Infarction With ST-segment Elevation

Czechia
Institute for the Care of Mother and Child, Prague...

Completed

Cross-sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

Pelvic Floor Disorders

Czechia
Charles University, Czech Republic

Recruiting

Surgical Mesh in Radical Cystectomy to Prevent Parastomal Hernias

Hernia | Bladder Cancer | Ileal Conduit

Czechia
Institute for the Care of Mother and Child, Prague...
General University Hospital, Prague; Bulovka Hospital

Recruiting

Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester. (ADAB)

Asherman Syndrome | Abortion Late

Czechia
National Institute of Mental Health, Czech Republic

Recruiting

Remote Peer Support in Prevention of Postpartum Depression

Postpartum Depression

Czechia
University Hospital Olomouc
Palacky University

Completed

Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome

Cataract | Age-related Cataract | Intraoperative Floppy Iris Syndrome | Adrenergic Receptor Antagonist Adverse Reaction

Czechia
Institute for the Care of Mother and Child, Prague...
Department of Obstetrics and Gynecology, Faculty of Medicine, CUNI, Pilsen... and other collaborators

Active, not recruiting

Effect of Laser Therapy on Vaginal Tissue

Vaginal Atrophy | Pelvic Floor Disorders

Czechia
General University Hospital, Prague
Czech Academy of Sciences

Recruiting

The Effect of Gluten-free Diet on Parkinsonism (GFREEPARK)

Parkinson Disease | Multiple System Atrophy | Non-celiac Gluten Sensitivity

Czechia
General University Hospital, Prague
Charles University, Czech Republic; Institute of Hematology and Blood Transfusion...

Recruiting

Selected Immunological Indicators and Microbiota in Patients With Premature Birth and Preeclampsia (PRIME)

Preterm Birth | Preeclampsia

Czechia
Institute for Clinical and Experimental Medicine
Sahlgrenska University Hospital, Sweden; University Hospital, Motol

Recruiting

Uterus Transplantation From Live Donors and From Deceased Donors - Clinical Study (UTxLD/DBD)

Infertility, Female | Mayer Rokitansky Kuster Hauser Syndrome | Absolute Uterine Factor Infertility | Mullerian Aplasia | Uterus; Absence, Congenital | Uterus Absence, Acquired

Czechia
University of Regensburg
University Hospital Ostrava; Brno University Hospital; University Hospital, Aachen

Recruiting

rTMS Add on Value for Amelioration of Negative Symptoms of Schizophrenia (RADOVAN)

Schizophrenia | Negative Symptoms With Primary Psychotic Disorder

Czechia, Germany
Institute for Clinical and Experimental Medicine

Completed

Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors (MoliDon)

Kidney Transplantation | Acute Kidney Injury

Czechia

Clinical Trials on Primary Myelofibrosis in Czechia

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