Clinical Trials on Progressive Primary Aphasia in Netherlands

Total 1712 results

Vesper Biotechnologies ApS

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001 in Healthy Participants (SORT-IN-1)

Dementia, Frontotemporal

Netherlands
Wave Life Sciences Ltd.

Terminated

Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)

ALS | FTD

Netherlands, United Kingdom
Alector Inc.

Active, not recruiting

A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

Frontotemporal Dementia

Canada, United States, Germany, United Kingdom, Italy, Netherlands
AviadoBio Ltd

Recruiting

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN) (ASPIRE-FTD)

Frontotemporal Dementia | FTD | FTD-GRN | Dementia, Frontotemporal

Netherlands, Spain, Poland, United States
FORUM Pharmaceuticals Inc

Unknown

Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Granulin Mutation

Belgium, United States, France, Italy, Netherlands, United Kingdom
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Alector Inc.

Active, not recruiting

A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

Frontotemporal Dementia

Spain, United States, Portugal, United Kingdom, France, Germany, Netherlands, Belgium, Australia, Italy, Turkey, Switzerland, Argentina, Canada, Greece, Sweden
Wave Life Sciences Ltd.

Terminated

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD) (FOCUS-C9)

ALS | FTD

Canada, Belgium, New Zealand, Netherlands, Australia, Sweden, United Kingdom, Ireland
TauRx Therapeutics Ltd

Completed

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD)

Behavioral Variant Frontotemporal Dementia (bvFTD)

United States, Australia, Canada, Croatia, Poland, Netherlands, United Kingdom, Spain, Germany, Italy, Romania, Singapore
Amsterdam UMC, location VUmc

Recruiting

Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS). (DOT-MS)

Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Netherlands
Radboud University Medical Center
UCB Pharma; Verily Life Sciences LLC

Recruiting

Personalized Parkinson Project PSP Cohort (PPP-PSP)

Brain Diseases | Movement Disorders | Neurodegenerative Diseases | Progressive Supranuclear Palsy

Netherlands
Amsterdam UMC, location VUmc

Recruiting

Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease (VIADUCT)

Graft Failure | Coronary Artery Disease Progression | Recurrent Angina After Coronary Artery Bypass Graft

Netherlands
Teleon Surgical B.V.
MaganaMed GmbH

Enrolling by invitation

Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.

Cataract | Aphakia | Clear Lens Exchange | Refractive Lens Exchange

Netherlands
TauRx Therapeutics Ltd

Terminated

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

Alzheimer's Disease | Behavioral Variant Frontotemporal Dementia

Korea, Republic of, United States, Spain, Taiwan, Canada, Belgium, Malaysia, United Kingdom, Australia, Singapore, Croatia, Finland, France, Germany, Netherlands, Romania, Russian Federation
University Medical Center Groningen

Enrolling by invitation

NAtural Course and Prognosis of PFIC and Effect of Biliary Diversion (NAPPED)

Progressive Familial Intrahepatic Cholestasis

Netherlands
Radboud University Medical Center
Stichting Bevordering Tandheelkundige Kennis of the Nederlands Tijdschrift...

Completed

7 Year Follow up Analysis on the Speed of Progression of Tooth Wear Using 3D Subtraction

Reflux Acid | Bruxism | Tooth Wear

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Proteomics and Genomics Combined With CT to Predict CVD (PREDICT-CVD)

Coronary Artery Disease Progression

Netherlands
Radboud University Medical Center

Completed

Clinical Outcomes After Implementation of COntinuous Vital Sign Monitoring On the General Ward. (COCOMO)

Clinical Deterioration

Netherlands
Rijnstate Hospital
University of Twente; Philips Research Eindhoven

Recruiting

Continuous Monitoring of Patients in and After the Acute Admission Ward to Optimize Clinical Pathways

Acute Disease | Monitoring | Clinical Deterioration

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Plaque Reversal With Early, Aggressive Lipid Lowering Therapy (EAGLE)

Coronary Artery Disease Progression

Netherlands
European Organisation for Research and Treatment...

Recruiting

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study (LEGATO)

First Progression of Glioblastoma

Netherlands, Austria, Germany
Catharina Ziekenhuis Eindhoven
Eindhoven University of Technology

Recruiting

Image-based Remote Monitoring in Cardiac Surgery Patients (FORSEE-3)

Vital Signs | Clinical Deterioration

Netherlands
Radboud University Medical Center

Active, not recruiting

Cerebral Contributions to Symptom Progression in PD

Parkinson Disease

Netherlands
Rijnstate Hospital
Radboud University Medical Center

Recruiting

Progression Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound Flow Imaging (CAS-PRO)

Carotid Artery Stenosis

Netherlands
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Nivolumab for Pediatric and Adult Relapsing/Refractory ALK+, for Evaluation of Response in Patients With Progressive Disease (Cohort 1) or as Consolidative Immunotherapy in Patients in Complete Remission After Relapse (Cohort 2) (NIVO-ALCL)

Relapsing/Refractory ALK+ Anaplastic Large Cell Lymphoma

France, Denmark, Netherlands
IntraBio Inc

Active, not recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo (ARPEGGIO)

Primary Progressive Multiple Sclerosis

United States, Canada, Germany, Italy, Netherlands, Poland, Russian Federation, Spain, Ukraine, United Kingdom
Alcon Research

Completed

Post-Market Clinical Investigation of the Clareon® IOL

Cataract | Aphakia

Australia, France, Germany, Italy, Netherlands, Spain, United Kingdom
Gustave Roussy, Cancer Campus, Grand Paris
National Cancer Institute, France; European Network for the Study of Adrenal...

Completed

First International Randomized Study in Malignant Progressive Pheochromocytoma and Paraganglioma (FIRSTMAPPP)

Malignant Progressive Pheochromocytoma and Paraganglioma (PPGL)

Italy, France, Germany, Netherlands
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

MAD Trial: Myopia Atropine Dose (MAD)

Progressive Myopia

Netherlands
Eli Lilly and Company
BioMS Technology Corp.

Completed

A Study for Patients With Secondary Progressive Multiple Sclerosis (MAESTRO-01)

Secondary Progressive Multiple Sclerosis

Canada, Estonia, Denmark, Finland, Germany, Latvia, Netherlands, Spain, Sweden, United Kingdom
M. Engelen

Recruiting

Quantifying Disease Progression in LBSL (LBSL)

Leukoencephalopathies | LBSL

Netherlands
Erasmus Medical Center

Recruiting

The Heartflow Coronary Disease Progression Evaluation Study (THRONE)

Coronary Artery Disease

Netherlands
Novartis Pharmaceuticals

Terminated

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS. (INFORMS)

Primary Progressive Multiple Sclerosis

United States, Belgium, Poland, Germany, Hungary, Turkey, Spain, Australia, Canada, Czechia, Switzerland, United Kingdom, Netherlands, France, Italy, Denmark, Finland, Sweden
Eli Lilly and Company
BioMS Technology Corp.

Terminated

A Study for Patients With Multiple Sclerosis (MAESTRO-02)

Secondary Progressive Multiple Sclerosis

Canada, Estonia, Denmark, Finland, Latvia, Spain, Sweden, United Kingdom, Germany, Netherlands
Hoffmann-La Roche

Active, not recruiting

Non-interventional Study of Ocrelizumab in Participants With Relapsing or Primary Progressive Multiple Sclerosis (MuSicalE)

Multiple Sclerosis

Belgium, United Kingdom, Netherlands, Serbia, Poland, Slovakia, Bulgaria, Turkey, Brazil, Italy, Russian Federation, Spain, Austria, Colombia, Romania, Kuwait, Chile, Dominican Republic, Egypt, Montenegro, Panama, Paraguay, Portugal, ... and more
Hoffmann-La Roche

Completed

A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

Multiple Sclerosis, Primary Progressive

United States, Canada, Australia, Hungary, Brazil, Finland, Italy, Germany, Romania, Lithuania, France, Greece, Peru, Portugal, Spain, Switzerland, Bulgaria, Ukraine, Israel, Poland, Austria, New Zealand, Netherlands, Belgium, Mexico, United... and more
Rheumazentrum Ruhrgebiet
PPD; Centocor BV; Trial Coordination Center, 9713 GZ Groningen

Unknown

Examination of Radiographic Progression, Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis

Belgium, Germany, Finland, France, Netherlands, United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...
Janssen-Cilag International NV

Completed

Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia Among Patients With Chronic Kidney Failure (PRIMS)

Chronic Kidney Failure | Pure Red-Cell Aplasia

Poland, United Kingdom, Belgium, Germany, Spain, Portugal, Australia, Switzerland, Finland, Greece, Sweden, Netherlands, Norway, Ireland, Denmark
Sanofi

Recruiting

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS) (PERSEUS)

Primary Progressive Multiple Sclerosis

Spain, Italy, Turkey, India, Israel, Bulgaria, Mexico, Greece, Portugal, United States, Argentina, Australia, Austria, Belarus, Belgium, Canada, Chile, China, Colombia, Croatia, Czechia, Denmark, Estonia, France, Georgia, Germany, Hungary, Japan and more
Amsterdam UMC, location VUmc
AstraZeneca; Brigham and Women's Hospital; University of Oxford; Klinikum Garmisch-Patenkirchen and other collaborators

Recruiting

Saracatinib Trial TO Prevent FOP (STOPFOP)

Fibrodysplasia Ossificans Progressiva

Germany, Netherlands, United Kingdom
Incyte Corporation

Recruiting

To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva (Progress)

Fibrodysplasia Ossificans Progressiva (FOP)

United States, France, Korea, Republic of, Spain, Italy, United Kingdom, Russian Federation, China, Australia, Brazil, Mexico, New Zealand, Argentina, Canada, Netherlands, Turkey, Chile, Germany, South Africa, Portugal
Maastricht University Medical Center
Funding: Stichting Internationaal Parkinson Fonds, The Netherlands

Completed

Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes

Parkinson's Disease | Supranuclear Palsy, Progressive | Multiple System Atrophy | Essential Tremor | Vascular Parkinsonism | Parkinsonian Syndrome | Drug Induced Parkinsonism

Netherlands
Regeneron Pharmaceuticals

Completed

A Study to Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva (LUMINA-1)

Fibrodysplasia Ossificans Progressiva

United States, Spain, Canada, France, Poland, Italy, Netherlands, United Kingdom
Biogen

Terminated

BG00012 and Delay of Disability Progression in Secondary Progressive Multiple Sclerosis (INSPIRE)

Multiple Sclerosis, Secondary Progressive

United States, Poland, Belgium, Slovakia, Czech Republic, Netherlands
Millennium Pharmaceuticals, Inc.

Completed

A Study of PS-341 Given to Patients With Multiple Myeloma Who Experienced Progressive Disease After Receiving Dexamethasone in M34101-039

Multiple Myeloma

United States, United Kingdom, Canada, Israel, France, Austria, Belgium, Germany, Ireland, Italy, Netherlands, Spain, Sweden
University Medical Center Groningen

Completed

Natural Disease Progress of Dupuytren Disease (DD)

Disease Progression | Dupuytren Contracture

Netherlands
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis (CONSONANCE)

Progressive Multiple Sclerosis (PMS)

United States, Canada, Brazil, France, Netherlands, Ireland, Germany, Italy, Poland, Russian Federation, Spain, Colombia, Morocco, Hungary, Denmark, Lebanon, Mexico, Costa Rica, Bosnia and Herzegovina, Czechia, Egypt, Guatemala, Panama and more
Erasmus Medical Center

Recruiting

Exhaled Breath Analysis Using eNose Technology as a Biomarker for Diagnosis and Disease Progression in Fibrotic ILD (ILDnose)

Pulmonary Fibrosis

United Kingdom, Germany, Netherlands, France
Dicerna Pharmaceuticals, Inc.

Terminated

A Study of DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Primary Hyperoxaluria Type 1

Netherlands, Germany

Clinical Trials on Progressive Primary Aphasia in Netherlands

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