Clinical Trials on Protozoan Infections

Total 56679 results

Pfizer
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS

HIV Infections | Toxoplasmosis, Cerebral

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients

HIV Infections | Toxoplasmosis, Cerebral

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of ABO809 in Healthy Participants

Cryptosporidium Infection, Cryptosporidiosis

United States
Douglas Postels, MD, MS
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

DON in Pediatric Cerebral Malaria

Malaria, Cerebral

Malawi
U.S. Army Medical Research and Development Command

Completed

Study of the Safety of Intravenous Artesunate

Malaria | Malaria, Cerebral

United States
U.S. Army Medical Research and Development Command
Walter Reed Army Institute of Research (WRAIR)

Completed

Study of the Safety of Intravenous Artesunate

Malaria | Malaria, Cerebral

United States
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Diagnosis of Toxoplasma Gondii Infection by Exploration of Cellular Immunity (TOXCELL) (TOXCELL)

Toxoplasmosis | Toxoplasmosis, Congenital | Toxoplasma Infections | Toxoplasmosis Recurrent

France
Makerere University

Unknown

Mannitol as Adjunct Therapy for Childhood Cerebral Malaria

Cerebral Malaria

Uganda
University of Texas, El Paso
National Institute of Allergy and Infectious Diseases (NIAID); Drugs for Neglected... and other collaborators

Active, not recruiting

New Therapies and Biomarkers for Chagas Infection (TESEO)

Chagas Disease | Trypanosoma Cruzi Infection

Bolivia
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection

HIV Infections | Toxoplasmosis, Cerebral

United States
Claude Bernard University

Unknown

Randomized Trial of Erythropoietin During Cerebral Malaria (EPOMAL)

Cerebral Malaria

Mali
Makerere University
Ministry of Health, Uganda; Sanofi-Synthelabo

Unknown

Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria

Cerebral Malaria

Uganda
National Institute of Allergy and Infectious Diseases...

Completed

A Systems Biology Approach to Malaria Immunity

Plasmodium Falciparum Infection

United States
Centers for Disease Control and Prevention
Columbia University; United States Agency for International Development (USAID) and other collaborators

Completed

Ethiopia Antimalarial in Vivo Efficacy Study 2012

Plasmodium Vivax Infection

Ethiopia
U.S. Army Medical Research and Development Command
United States Agency for International Development (USAID); University of Oxford and other collaborators

Completed

Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults

Malaria

United States
Abbott Rapid Dx
Bill and Melinda Gates Foundation

Completed

Performance Evaluation of Malaria Plus Rapid Diagnostic Tests (RDTs) for the Detection of Plasmodium Infections in Patients With Symptoms Suggestive of Malaria

Malaria

Ethiopia
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Sanaria Inc.

Completed

Susceptibility of Gambian Adults to PfSPZ-Challenge Infection in the Controlled Human Malaria Infection Model (CHMI-Gambia1)

Malaria

Gambia
Sanaria Inc.
Walter Reed Army Institute of Research (WRAIR); Naval Medical Research Center; Military Infectious Diseases Research Program (MIDRP)

Completed

A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses

Malaria

United States
Sanaria Inc.
Institute of Tropical Medicine, University of Tuebingen

Completed

Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults

Malaria

Germany
Sanaria Inc.
Radboud University Medical Center

Completed

Experimental Human Malaria Infection by PfSPZ

Malaria

Netherlands
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Research and Development...

Completed

Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Adults

Malaria

Tanzania
Universitas Padjadjaran

Recruiting

Dexamethasone for Cerebral Toxoplasmosis (De-Tox)

Toxoplasmosis, Cerebral

Indonesia
University of Oxford
Chittagong Medical College and Hospital

Completed

Severe and Cerebral Malaria Investigated Through Host Metabolomics

Severe Malaria

Bangladesh
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria (LVT1)

Epilepsy | Seizure | Cerebral Malaria

Malawi
Macfarlane Burnet Institute for Medical Research...
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; Health Poverty Action and other collaborators

Not yet recruiting

Reducing Malaria Transmission in Forest-going Mobile and Migrant Populations in Lao PDR and Cambodia

Plasmodium Infection
National Institute of Allergy and Infectious Diseases...

Completed

Malaria Vaccine for Children in Mali

Malaria | Malaria Infection

Mali
Michigan State University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Treating Brain Swelling in Pediatric Cerebral Malaria (TBS)

Malaria, Cerebral

Malawi
Epicentre
Harvard Medical School (HMS and HSDM); Massachusetts General Hospital; Mbarara... and other collaborators

Completed

Evaluation of the Efficacy and Safety of Inhaled Nitric Oxide as Adjunctive Treatment for Cerebral Malaria in Children

Malaria, Cerebral

Uganda
National Institute of Allergy and Infectious Diseases...

Completed

Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients

HIV Infections | Toxoplasmosis, Cerebral

United States
Sohag University

Recruiting

Genetic Diversity of Toxoplasma Gondii in Cancer Patients

Cancer | Toxoplasma Gondii Infection

Egypt
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis (TOXIC)

Toxoplasmosis

France
University Hospital, Limoges

Completed

Cerebral Toxoplasmosis and AIDS (TOXODFA)

AIDS | Cerebral Toxoplasmosis

France
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM (LVT2)

Epilepsy | Seizure | Cerebral Malaria

Malawi
Medicines for Malaria Venture
Q-Pharm Pty Limited

Terminated

MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants

Malaria, Falciparum

Australia
National Institute of Allergy and Infectious Diseases...

Completed

PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States

Plasmodium Falciparum Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Adenovirus Vaccine for Malaria

Plasmodium Falciparum Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Chloroquine Alone or in Combination for Malaria in Children in Malawi

Plasmodium Falciparum Infection

Malawi
Macfarlane Burnet Institute for Medical Research...
National Malaria Control Program, Myanmar; Health Poverty Action

Not yet recruiting

Reducing Malaria Transmission in Forest-going Mobile and Migrant Populations in Myanmar

Plasmodium Falciparum Infection
Hospices Civils de Lyon

Recruiting

Lyon Cohort of Maternal and Congenital Toxoplasma Infections

Toxoplasmosis, Congenital

France
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS

HIV Infections | Toxoplasmosis, Cerebral

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso

Plasmodium Falciparum Infection

Burkina Faso
University of Oxford
Sanaria Inc.

Completed

Optimisation of Controlled Human Malaria Infection Using Sporozoites Administered by Needle and Syringe

Malaria | Plasmodium Falciparum

United Kingdom
Paxmedica

Completed

A Retrospective Analysis of Suramin Treatment for Stage 1 TBR

Trypanosoma Brucei Rhodesiense; Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Efficacy of Sanaria's PfSPZ-CVac in Malian Adults

Plasmodium Falciparum Infection

Mali
Duke University

Completed

Molecular Diagnostic Methods for Detection of Plasmodium Knowlesi

Plasmodium Knowlesi Infection

Malaysia
National Institute of Allergy and Infectious Diseases...

Completed

PfSPZ Challenge in Non-immune Adults in Baltimore, USA

Plasmodium Falciparum Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

rCSP/AP10-602 [GLA-LSQ] Vaccine Trial

Plasmodium Falciparum Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites

Plasmodium Falciparum Infection

United States
Idorsia Pharmaceuticals Ltd.

Completed

Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects

Healthy Subjects

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Malaria Challenge With NF54 Strain

Plasmodium Falciparum Infection

United States

Clinical Trials on Protozoan Infections

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