Clinical Trials on Proximal Spinal Muscular Atrophy in Switzerland

Total 60 results

University Hospital, Basel, Switzerland

Enrolling by invitation

Spinal Cord Gray Matter Imaging in Spinal Muscular Atrophy

Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type III

Switzerland
Hoffmann-La Roche

Completed

Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.

Healthy Volunteer, Muscular Atrophy, Spinal

Switzerland
University Hospital, Basel, Switzerland

Completed

Association Between Lumbar Muscle Atrophy, Sagittal Pelvic Alignment and Stenosis Grade in Patients With Degenerative Lumbar Spinal Stenosis (AtrophyLSS)

Lumbar Spinal Stenosis (LSS)

Switzerland
Clinique Romande de Readaptation
Swiss Paraplegic Centre Nottwil

Unknown

Characterization of the Changes in the Signalling Pathways During Spinal Cord Injury-induced Skeletal Muscle Atrophy

Spinal Cord Injuries | Muscle Atrophy

Switzerland
Hoffmann-La Roche

Active, not recruiting

A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy (Jewelfish)

Spinal Muscular Atrophy

Belgium, United States, United Kingdom, France, Poland, Italy, Switzerland, Netherlands, Germany
Hoffmann-La Roche

Terminated

A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)

Muscular Atrophy, Spinal

France, Turkey, Canada, United States, Italy, Netherlands, Sweden, Switzerland, United Kingdom
Hoffmann-La Roche

Completed

Investigate Safety, Tolerability, PK, PD and Efficacy of Risdiplam (RO7034067) in Infants With Type1 Spinal Muscular Atrophy (FIREFISH)

Muscular Atrophy, Spinal

Belgium, United States, China, Spain, Japan, France, Brazil, Croatia, Italy, Russian Federation, Saudi Arabia, Serbia, Switzerland, Turkey, Ukraine, Poland
University of Zurich
Foundation Wings For Life

Completed

Plasticity of Grey and White Matter in Response to Motor Skill Training in Healthy Individuals and Those With Spinal Cord Injury

Investigating Spinal Atrophy in Patients With Spinal Injury

Switzerland
University Department of Geriatric Medicine FELIX...

Completed

Prevalence of Sarcopenia in Geriatric Patients

Sarcopenia

Switzerland
Patrizia D'Amelio

Not yet recruiting

Maintaining Immune and Mitochondrial Functions in Old Adults With SAfe Nutrition. (MIMOSA)

Malnutrition | Sarcopenia

Switzerland
University Hospital, Basel, Switzerland

Completed

Strength and Strength-ratio of Hip Rotator Muscles at Soccer Players

Muscular Atrophy | Hip Injuries | Dysfunction

Switzerland
Thimo Marcin
Bern University of Applied Sciences

Completed

Nutritional Therapy in Patients at Risk for Malnutrition and Sarcopenia in Pulmonary Rehabilitation

Malnutrition | Sarcopenia

Switzerland
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Hôpital Fribourgeois; Kantonsspital Baden

Recruiting

An INtervention TO Improve MOBility of Older Hospitalized Patients (INTOMOB)

Iatrogenic Disease | Sarcopenia | Hospital Mobility | Mobility Limitation | Life-Space | Functional Status | Hospital-Acquired Condition | Muscle Atrophy or Weakness

Switzerland
Undine Lehmann, Dr.
Rehab Basel; Berner Reha Zentrum AG; Klinik Barmelweid; University Department of... and other collaborators

Completed

The Prevalence of Malnutrition and Sarcopenia in Swiss Rehabilitation Settings (Malnut-Reha)

Malnutrition | Sarcopenia

Switzerland
Dirk Fischer

Completed

L-Citrulline in Patients With Post-Polio Syndrome

Post-Polio Syndrome

Switzerland
Insel Gruppe AG, University Hospital Bern
University of Bern

Completed

Goal-directed Mobilization of Medical Inpatients (GoMob-in)

Delirium | Sarcopenia | Fall | Mobility Limitation | Hospital Acquired Condition | Immobility Syndrome

Switzerland
Christian Müller, MD
University Hospital Inselspital, Berne; Medical University Innsbruck; University... and other collaborators

Recruiting

Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease (H&M)

Muscle Weakness | Muscle Atrophy | Muscle Spasticity | Muscle Cramp | Muscle Soreness | Muscle Damage | Myopathy | Muscle Injury

Switzerland, Austria
University Hospital Inselspital, Berne
University of Lausanne Hospitals; Leiden University Medical Center

Completed

The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism

Sarcopenia | Subclinical Hypothyroidism

Switzerland, Netherlands
Institute of Molecular and Clinical Ophthalmology...
Boehringer Ingelheim

Active, not recruiting

Optical Coherence Tomography and Microperimetry Biomarker Evaluation in Patients With Geographic Atrophy Study (OMEGA)

Age-Related Macular Degeneration | Geographic Atrophy | Visual Field Defect, Central Scotoma of Both Eyes

Switzerland
University Hospital, Basel, Switzerland
University Children's Hospital Basel

Unknown

Spinal Cord Gray Matter Imaging in Post Polio Syndrome

Post-polio Syndrome

Switzerland
University of Zurich
Swiss National Science Foundation; University Hospital, Basel, Switzerland; University... and other collaborators

Recruiting

Sarcopenia Prevention With a Targeted Exercise and Protein Supplementation Program (STRONG)

Frailty | Sarcopenia | Fall | Malnutrition; Protein

Switzerland
Swiss Paraplegic Centre Nottwil

Completed

"Validated Language Transfer of the Spinal Cord Injury-Spasticity Evaluation Tool to German Language" (SCI-SETde)

SCI - Spinal Cord Injury | Spastic

Switzerland
Swiss Paraplegic Centre Nottwil
Medical University of Vienna

Withdrawn

Carry-over Effects of Repetitively Applied Transcutaneous Spinal Cord Stimulation on Spasticity (SCS-CorE)

Spinal Cord Injuries | Spasticity, Muscle

Switzerland
Swiss Paraplegic Centre Nottwil

Completed

Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury (ESWT)

Spinal Cord Injury | Spasticity

Switzerland
Swiss Paraplegic Centre Nottwil

Withdrawn

Absorption of Rivaroxaban in Patients With Cervical Spinal Cord Injury (rivaroxaban)

Thromboembolism | Spinal Cord Injuries

Switzerland
Oliver Faude

Recruiting

Agility Training for Older Adults to Improve Fall Risk Factors (AgilE)

Sarcopenia | Aging | Cognitive Decline | Age-Related Loss of Skeletal Muscle Mass

Switzerland
StemCells, Inc.

Completed

Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Patients With Thoracic Spinal Cord Injury

Spinal Cord Injury | Spinal Cord Trauma | Thoracic Spinal Cord Injury | Spinal Cord Injury Thoracic

Canada, Switzerland
Boehringer Ingelheim

Terminated

Global Atrophie Biomarker Evaluation Study (GABiE) (GABiE)

Age-related Macular Degeneration

United States, Switzerland
University Children's Hospital, Zurich

Unknown

Cardiac Involvement in Patients With Duchenne/Becker Muscular Dystrophy

Duchenne / Becker Muscular Dystrophy

Switzerland
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Duchenne's Muscular Dystrophy

Duchenne's Muscular Dystrophy (DMD)

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Protein Delivery in Intermittent and Continuous Enteral Nutrition in ICU Patients (ProBoNo)

Muscle Wasting in Critically Ill

Switzerland
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Becker's Muscular Dystrophy

Becker's Muscular Dystrophy (BMD)

Switzerland
Philippe Terrier
Swiss Heart Foundation

Unknown

Gait Adaptation for Stroke Patients With Augmented Reality (GASPAR)

Stroke | Traumatic Brain Injury | Spinal Cord Injury

Switzerland
Swiss Paraplegic Centre Nottwil

Completed

Prevention of Orthostatic Hypotension With Electric Stimulation in Persons With Acute SCI

Orthostatic Hypotension | Spinal Cord Injury

Switzerland
Ente Ospedaliero Cantonale, Bellinzona

Completed

Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?

Fluid Overload | Regional Anesthesia Morbidity | Anesthesia; Adverse Effect, Spinal and Epidural

Switzerland
Abbott Nutrition

Completed

Evaluation of an Oral Nutritional Supplement Containing AN777

Malnutrition | Sarcopenia

Spain, United States, Italy, Poland, Belgium, Mexico, Switzerland, United Kingdom
Swiss Federal Institute of Technology

Completed

Evaluation of a Textile Scapula Orthosis (ScapOrthosis)

Muscle Weakness | Muscular Dystrophies | Muscular Dystrophy | Muscular Dystrophy, Facioscapulohumeral | Scapular Dyskinesis | Muscular Weakness

Germany, Switzerland
Novartis Pharmaceuticals

Completed

A 24-week Off-drug Extension Study in Sarcopenic Elderly Who Completed Treatment in the 6-month Core Study

Sarcopenia

Taiwan, United States, Belgium, Russian Federation, Korea, Republic of, Japan, France, Denmark, Australia, Czechia, Spain, Switzerland
University of Bern
University Hospital Inselspital, Berne; University of Lausanne Hospitals; University... and other collaborators

Recruiting

Swiss Registry for Neuromuscular Disorders (Swiss-Reg-NMD)

Congenital Muscular Dystrophy | SMA | DMD | BMD | IMD

Switzerland
Novartis Pharmaceuticals

Completed

Dose Range Finding Study of Bimagrumab in Sarcopenia

Sarcopenia

Belgium, United States, Australia, Germany, Spain, Taiwan, France, Korea, Republic of, Japan, Russian Federation, Denmark, Czechia, Switzerland
Cantonal Hospital of St. Gallen
ALS Association

Completed

Randomized Placebo-Controlled Crossover Trial With THC (Delta 9-Tetrahydrocannabinol) for the Treatment of Cramps in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis | Cramps

Switzerland
University Hospital, Basel, Switzerland

Completed

Tamoxifen in Duchenne Muscular Dystrophy (TAMDMD)

Duchenne Muscular Dystrophy

France, Spain, Germany, Netherlands, Switzerland, United Kingdom
Hoffmann-La Roche

Terminated

Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)

Geographic Atrophy

United States, United Kingdom, Germany, France, Turkey, Australia, Austria, Belgium, Canada, Denmark, Hungary, Italy, Poland, Slovakia, Spain, Switzerland, Portugal, Netherlands, Peru
Hoffmann-La Roche

Terminated

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (CHROMA)

Geographic Atrophy

Canada, United States, Belgium, Peru, Argentina, Australia, Austria, Denmark, France, Germany, Hungary, Italy, Mexico, Netherlands, Poland, Slovakia, Spain, Switzerland, United Kingdom
Hoffmann-La Roche

Terminated

A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (SPECTRI)

Geographic Atrophy

United States, United Kingdom, Netherlands, Germany, Belgium, Poland, Spain, Argentina, Australia, Hungary, Italy, Portugal, France, Turkey, Austria, Russian Federation, Mexico, Peru, Denmark, Slovakia, Sweden, Switzerland
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Active, not recruiting

A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression (INTERCEPT-AMD)

Atrophy | Age Related Macular Degeneration | Prediction | Intermediate AMD

Portugal, France, Germany, Ireland, Italy, Netherlands, Spain, Switzerland, United Kingdom
Janssen Research & Development, LLC

Recruiting

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Geographic Atrophy

Netherlands, United States, Belgium, Italy, Germany, United Kingdom, Denmark, Spain, Czechia, Switzerland, Turkey, Canada, Hungary, Portugal, Poland, Australia, Sweden
University Hospital, Basel, Switzerland

Completed

Gait Asymmetry Assessed Using Portable Gait Analysis System (Asymmetry)

Knee Osteoarthritis | Hip Osteoarthritis | Ankle Osteoarthritis | Muscle Contracture | Lumbar Spine Stenosis

Switzerland
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery

Muscle Wasting (Atrophy) After Hip Fracture Surgery

Colombia, Belgium, Hungary, Taiwan, Spain, Czechia, United States, France, Germany, Turkey, Japan, Russian Federation, United Kingdom, Argentina, Australia, Mexico, Chile, Switzerland, Austria
Santhera Pharmaceuticals

Completed

Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD) (DELOS)

Muscular Dystrophy, Duchenne | Ambulatory Care

United States, Spain, Austria, Belgium, France, Germany, Italy, Netherlands, Sweden, Switzerland

Clinical Trials on Proximal Spinal Muscular Atrophy in Switzerland

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