Clinical Trials on Pupil Disorders

Total 144123 results

Vienna Institute for Research in Ocular Surgery

Unknown

Methods to Manage Intra-operative Floppy-iris Syndrome and Poor Pupil Dilation in Cataract Surgery (IFIS)

Management of Intraoperative Floppy-iris Syndrome and Small Pupils With Different Mechanical Devices

Austria
Yangzhou University

Completed

The Guiding Significance of Pupil Monitoring in the Perioperative Period

Pupil Diameter | Pupil Contraction Rate | Pupil Light Reflection

China
Vrije Universiteit Brussel

Completed

Pupil Dilation and Analgesia Nociception Index

Pain

Belgium
Northwest Kansas Surgery Center

Completed

Preoperative Cataract Pupillary Dilation: Inpatient At The Ambulatory Surgery Center vs Outpatient Dilation Prior To Arrival At The Ambulatory Surgery Center

Pupil Dilation Prior to Cataract Surgery In-patient | Pupil Dilation Prior to Cataract Surgery Out-patient
University Hospital, Antwerp

Completed

Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial (Pain@OR-kids)

Pain | Monitoring, Intraoperative

Belgium
VA Palo Alto Health Care System

Completed

Color and Pupil Function

Pupil
Wenzhou Medical University

Completed

Study of Intracameral Adrenaline for Pupil Dilation Without Topical Mydriatics in Refractive Cataract Surgery

Cataract

China
Santa Casa de Misericórdia de Belo Horizonte

Completed

Efficacy of the Canabrava/s Pupil Expansion Device in Cataract Surgery With Small Pupils: The First 30 Cases

Cataract | Small Pupil
The University of Texas Medical Branch, Galveston
University of Nevada, Reno

Active, not recruiting

Measuring Relative Afferent Pupillary Defect (RAPD)

Relative Afferent Pupil Defect (RAPD)

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Evaluation of an Iris Dilatation Ring in Cataract Surgery (ADICC-ID) (ADICC-ID)

Small Pupil

France
He Eye Hospital

Completed

Quality of Vision in Implantable Collamer Lens (ICL)

Pupil Diameter

China
University Hospital Tuebingen

Completed

Monochromatic Digital-Pupillometry With Two Automated Devices in Comparison to Manual Measurements on Digital Photographs

Pupil Examination
University Hospital, Antwerp

Completed

Pain Assessment by Pupil Dilation Reflex (PDR) and Pupillary Pain Index (PPI) in Response to Noxious Stimulation in Anesthetized Adults

Nociceptive Pain | Monitoring, Intraoperative

Belgium
Tel-Aviv Sourasky Medical Center

Unknown

Evaluation of the FIM - a Non Invasive Device for Temporarily and Quick Pupil Dilation (Mydriasis) (TP 7601-CL)

Pupil Dilation

Israel
Shahid Beheshti University of Medical Sciences

Unknown

Pupil Centroid Shift Compensation in Photorefractive Keratectomy Candidates

Pupil Centroid Shift

Iran, Islamic Republic of
Meir Medical Center

Completed

Use of APX 100 Device for Small-pupil Cataract Surgery and Intraoperative Floppy-iris Syndrome

Intraoperative Floppy Iris Syndrome | Miosis Disorder

Israel
University College, London

Completed

The PUPIL Study - Automated, Quantitative Pupil Assessment Using Binocular OCT

Healthy Volunteers | Pupil Anomaly | Relative Afferent Pupil Defect

United Kingdom
Denver Health and Hospital Authority

Completed

Pupil Dilation for Treatment of IFIS

Intraoperative Floppy Iris Syndrome

United States
University of Medicine and Dentistry of New Jersey

Completed

Effects of Sevoflurane and Propofol on Light Flash Evoked Pupillometry

Measurement of Pupil Diameter

United States
University of California, San Francisco

Not yet recruiting

Efficacy of the MydCombi on Pupillary Dilation in Pediatric and Adult Patients

Dilation | Pupil Reaction Absent

United States
Arkansas Tech University

Active, not recruiting

Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

Electroencephalography | no Condition | Pupil Diameter

United States
National Taiwan University Hospital

Completed

Evaluation of Position-induced Cyclorotation Between Wavefront Measurement and Refractive Surgery by the Iris Registration Method

Eye Cyclorotation Degree | Pupil Shift

Taiwan
He Eye Hospital

Recruiting

Comparison of Two Different Pupillometer

Measurement of Pupil Diameter

China
Denver Health and Hospital Authority
University of Colorado, Denver

Terminated

Exploration of Pupil Dilation in Horner's Patients Taking Flomax

Horner Syndrome

United States
Eyenovia Inc.

Completed

Evaluation of Pupil Dilation Speed With the MAP Dispenser (SPEED)

Mydriasis

Mexico
Eyenovia Inc.

Completed

Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-1)

Mydriasis

United States
Boehringer Ingelheim

Completed

Study to Assess the Influence of Three Different α-antagonists and Placebo on the Extent of Weekly Phenylephrine-induced Mydriasis at Three Different Concentrations of Phenylephrine in Healthy Male Volunteers

Healthy
Eyenovia Inc.

Completed

Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil Dilation

Mydriasis

United States
Eyenovia Inc.

Completed

Study of the Safety, Efficacy and PK of EYN-1601 in Dilation of the Pupil

Mydriasis

United States
Eyenovia Inc.

Completed

Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-2)

Mydriasis

United States
Second Affiliated Hospital, School of Medicine,...

Unknown

Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Complicated and Combined Cataract Surgery

Cataract | Corneal Opacity | Lens Subluxation | Small Pupil | Hypermature Cataract

China
Johns Hopkins University

Terminated

Optimal Method for Mydriasis in Cataract Surgery

Cataract

United States
University Hospital, Antwerp

Completed

Pupillary Dilation Reflex (PDR) Evaluation During General Anesthesia

Pain

Belgium
Prisma Health-Upstate

Completed

Wearing-Off Period of Pharmacological Dilation and Anisocoria

Anisocoria

United States
Medical University of Graz

Completed

Comparison Mydriasis by Mydrane With Topical Drop Application

Cataract

Austria
Seoul National University Hospital

Completed

Pupillometer as a Pain Index During General Anesthesia

Pain | Anesthesia, General | Pupil

Korea, Republic of
Changzhou Second People's Hospital affiliated with...

Recruiting

Sutureless Intrascleral Intraocular Lens Fixation and Modified Iris Cerclage Pupilloplasty

Aphakia | Mydriasis

China
Carmel Medical Center

Completed

Lidocaine Usage for Pupil Dilatation (Mydriasis)

Cataract
Clinica Oftamologica Zona Sul

Unknown

Effect of Anti-inflammatory Topical Prednisolone, Nepafenac and Ketorolac in Intra-operative Mydriasis in Facetectomies

Cataract

Brazil
Assiut University

Unknown

Nepafenac Versus Ketorolac Eye Drops in Prevention of Intraoperative Miosis During Cataract Surgery

Cataract | Miosis
Seoul National University Hospital

Unknown

Effects of Volatile and Intravenous Anesthetics on Pupillary Function

Pupillary Functions, Abnormal

Korea, Republic of
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis

Mydriasis | Dilation

United States
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3) (MIRA-3)

Mydriasis | Dilation

United States
Ocuphire Pharma, Inc.

Completed

Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects (MIRA-4)

Mydriasis | Dilation

United States
Clinica Oftalmologica TACIR

Completed

Correlation of Pupillary Diameter Changewith Age and Anterior Chamber Depth After Cataract Surgery

Pupillary Disorders

Spain
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced Mydriasis

Mydriasis | Dilation

United States
Kirsten Elwischger, MD

Withdrawn

Influence of Gaze Shift and Emotions on Symptoms of Blepharospasm

Pupillary Occlusion

Austria
Baskent University

Completed

Clinical Factors Associated Floppy Iris

Pupil Constriction | Iris Floppiness | Iris Prolapsus From the Wound

Turkey
University of California, San Francisco
Nanodropper, Inc.

Completed

Efficacy of the Nanodropper Device on Pupillary Dilation

Dilation

United States
Basque Health Service

Active, not recruiting

Stimulation and Validation of the Pupillary Dilation for the Detection of Pain in Analgosedated Patients Under Mechanically Ventilation in Intensive Care Unit

Pain

Spain

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