Clinical Trials on Radiation Exposure in South Africa

Total 69 results

Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Healthcare...

Recruiting

Community-based Venues for Delivery of Healthcare Services: Proof of Concept Pilot

STI | Contraceptive Usage | Pre-Exposure Prophylaxis

South Africa
RTI International
United States Agency for International Development (USAID); FHI 360; Wits Reproductive...

Completed

CHARISMA Expansion Study (CHARISMA)

Relationship Dynamics | Pre-exposure Prophylaxis (PrEP) Adherence

South Africa
Duke University
National Institute of Mental Health (NIMH); University of Cape Town

Completed

Improving the Health of South African Women With Traumatic Stress in HIV Care (ImpACT)

HIV | Trauma Exposure

South Africa
University of California, San Francisco
National Institute of Mental Health (NIMH); University of Witwatersrand, South...

Recruiting

Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings

Depression | Pre-Exposure Prophylaxis

South Africa
Columbia University
National Institute of Mental Health (NIMH); University of Cape Town

Recruiting

A Randomized Trial of ImpACT+, a Coping Intervention for HIV Infected Women With Sexual Trauma in South Africa (ImpACT+)

HIV | Trauma Exposure

South Africa
National Baromedical Services

Terminated

Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries

Radiation Injuries

United States, Australia, Mexico, South Africa, Turkey
University of Virginia
University of Venda

Active, not recruiting

Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa

Environmental Exposure | Diarrhoea;Infectious;Presumed | Diarrhea, Infantile | Diarrhea Tropical | Enteropathy | Malnutrition, Child

South Africa
Walter Sisulu University
Medical University of Graz; Nelson Mandela Academic Hospital; Umtata General...

Not yet recruiting

Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero (ARTMOMSBABES)

In Utero Drug Exposure

South Africa
Johns Hopkins Bloomberg School of Public Health
National Institute of Mental Health (NIMH); Unity Health Toronto; TB/HIV Care

Recruiting

Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa

HIV Infections | Pre-exposure Prophylaxis

South Africa
Johns Hopkins Bloomberg School of Public Health
National Institute of Mental Health (NIMH); TB/HIV Care; Community Media Trust

Completed

Le Kip Kip: A Campaign to Change Social Norms and Build Sustainable Demand for PrEP Among Women in South Africa

HIV Infections | Pre-exposure Prophylaxis

South Africa
Medical University of South Carolina

Enrolling by invitation

Bone-Lead Level Associations With Brain and Mental Health

Lead Exposure

United States
Medical University of South Carolina

Completed

Tin Filter Calcium Scoring

Radiation Dose Reduction

United States
Stratpharma AG

Completed

StrataXRT vs. Standard Clinical Practice in the Prevention and Treatment of Radiation Dermatitis

Radiation Dermatitis

Australia
Sanford Health

Completed

Study of Topical Superoxide Dismutase to Treat Radiation Induced Fibrosis (Sodermix)

Radiation Induced Fibrosis to the Head and Neck

United States
University of Southern Denmark
Region of Southern Denmark; Hospital of Southern Jutland; Horizon 2020 - European... and other collaborators

Completed

The Impact of Red Meat and Whole-grains Intake on the Colonic Mucosal Barrier

Dietary Exposure | Mucus Colitis | Inflammation, Colon

Denmark
University of Sydney
Western Sydney Local Health District

Active, not recruiting

Collection of Head Images During Radiotherapy (CHIRP)

Head and Neck Neoplasms | Radiation Therapy Complication

Australia
University of Aarhus
Aarhus University Hospital; Westmead and Blacktown Hospital, Sydney West Radiation...

Recruiting

Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer (ASPECT)

Lung Cancer | Pulmonary Disease | Radiation Pneumonitis | Lung Function Decreased | Radiation-Induced Disorder

Australia, Denmark
Reata, a wholly owned subsidiary of Biogen
AbbVie

Completed

RTA 408 Lotion in Patients at Risk for Radiation Dermatitis - PRIMROSE

Breast Cancer

United States
Andrew Carr

Completed

Safety, Tolerability,and Adherence to Co-formulated Tenofovir-emtricitabine-rilpivirine Used as HIV Nonoccupational Post-exposure Prophylaxis in Men Who Have Sex With Men. (EPEP)

HIV Nonoccupational Post-exposure Prophylaxis in Men Who Have Sex With Men

Australia
Leiden University Medical Center

Unknown

One-visit Multi-site Intradermal Rabies Vaccination - Dose Finding

Rabies Pre-exposure Prophylaxis

Netherlands
Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

HIV | HIV Pre-exposure Prophylaxis

United States, South Africa, Israel
Wake Forest University Health Sciences

Completed

Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer (ACUPUNCTURE)

Head and Neck Cancer | Radiation Toxicity | Radiation-Induced Xerostomia | Oral Complications of Chemotherapy and Head/Neck Radiation

United States
University of Sydney
Western Sydney Local Health District

Recruiting

Surface Monitoring Technology to Remove The Mask - Stage 1 (SMART)

Head and Neck Cancer | Anxiety | Radiation Therapy Complication

Australia
North Central Cancer Treatment Group
National Cancer Institute (NCI)

Completed

Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ

Breast Cancer | Radiation Toxicity | Skin Reactions Secondary to Radiation Therapy | Dermatologic Complications

United States
Eli Lilly and Company

Completed

Duloxetine Versus Placebo in Chronic Low Back Pain

Back Pain Without Radiation

United States
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Terminated

Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy

Lung Cancer | Pulmonary Complications | Radiation Fibrosis

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; National Institutes of Health... and other collaborators

Recruiting

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy (AL)

Visual Impairment | Radiation Retinopathy

United States
Vaxine Pty Ltd
Flinders Medical Centre

Completed

Safety and Efficacy Study of Adjuvanted Prophylactic Hepatitis B Vaccine

Exposure to Hepatitis B Virus

Australia
Sound Pharmaceuticals, Incorporated
Medical University of South Carolina; Cystic Fibrosis Foundation

Enrolling by invitation

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

Ototoxicity

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Brain and Central Nervous System Tumors | Radiation Toxicity

United States
Avera McKennan Hospital & University Health Center

Terminated

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Breast Cancer | Breast Tumors

United States
Kevin Winthrop
Medical University of South Carolina; Mayo Clinic; University of Washington; National... and other collaborators

Not yet recruiting

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

Ototoxicity, Drug-Induced

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy

Head and Neck Cancer | Radiation Toxicity

United States
Galera Therapeutics, Inc.

Completed

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

Radiation Induced Oral Mucositis

United States, Canada, Puerto Rico
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Recruiting

Prospective Urban Rural Epidemiology Study (PURE)

Cardiovascular Diseases | Lung Diseases | Cancer | Risk Factor, Cardiovascular | Health Behavior | Injuries | Environmental Exposure | Renal Disease | Communicable Disease

India, Saudi Arabia, Iran, Islamic Republic of, Peru, Pakistan, Argentina, Bangladesh, Brazil, Canada, Chile, China, Colombia, Kazakhstan, Kyrgyzstan, Malaysia, Palestinian Territory, occupied, Philippines, Poland, Russian Federation and more
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy

Diarrhea | Radiation Enteritis

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Radiation Therapy in Treating Patients With Prostate Cancer

Sexual Dysfunction | Prostate Cancer | Radiation Toxicity | Psychosocial Effects of Cancer and Its Treatment

United States, Canada
Royal Prince Alfred Hospital, Sydney, Australia

Completed

Cardiotoxicity of Adjuvant Trastuzumab (CATS)

Heart Failure | Breast Neoplasms

Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United States, Canada
Ortho-McNeil Janssen Scientific Affairs, LLC
Grünenthal GmbH

Completed

NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain

Pain | Back Pain | Low Back Pain | Back Pain With Radiation

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma

Skin Angiosarcoma | Skin Radiation-Related Angiosarcoma | Visceral Angiosarcoma

United States, Guam
Gilead Sciences

Active, not recruiting

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection (PURPOSE 2)

Pre-Exposure Prophylaxis of HIV Infection

United States, Thailand, Brazil, Peru, Argentina, South Africa, Mexico, Puerto Rico
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer

Head and Neck Cancer | Skin Reactions Secondary to Radiation Therapy

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Metastatic Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States, Canada
Institut de Recherches Internationales Servier
Celgene Corporation

Active, not recruiting

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Untreated AML | Newly Diagnosed Acute Myeloid Leukemia (AML) | AML Arising From Myelodysplastic Syndrome (MDS) | AML Arising From Antecedent Hematologic Disorder (AHD) | AML Arising After Exposure to Genotoxic Injury

United States, Germany, Netherlands
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States, Canada, Switzerland
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United States, Canada

Clinical Trials on Radiation Exposure in South Africa

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CROs in Equatorial Guinea

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