Clinical Trials on Refractory Shock

Total 4540 results

The First Hospital of Jilin University

Not yet recruiting

Comparison of Analgesic and Sedative Effects of Esmketamine and Remifentanil Combined With Propofol Respectively in Septic Shock Patients With Invasive Mechanical Ventilation

Patients With Septic Shock Admitted to the ICU on Invasive Mechanical Ventilation
Assistance Publique - Hôpitaux de Paris

Completed

Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock (PRECISE)

Severe Sepsis or Septic Shock in Pediatric Intensive Care Unit

France
Rachael Cusack
Grifols Biologicals, LLC

Recruiting

Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock

Sepsis | Septic Shock | Sepsis, Severe

Ireland
Centre Hospitalier Universitaire Dijon

Recruiting

Use of Neurostimulation as a Tool for Reconditioning the Neuromuscular System of Patients Admitted to the ICU for Septic Shock (STIMUREA)

Septic Shock

France
University Hospital, Angers

Recruiting

Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study (MEFDASE)

Septic Shock | Multiple Organ Failure

France
Spectral Diagnostics (US) Inc.

Recruiting

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (TIGRIS)

Septic Shock | Endotoxemia

United States
The University of Texas Health Science Center,...

Terminated

Resuscitation With Plasma in Surgical and Trauma Patients With Septic Shock

Septic Shock

United States
Santa Barbara Cottage Hospital

Active, not recruiting

Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock

Septic Shock | Severe Sepsis

United States
Ege University

Completed

As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPAR (suPAR)

Septic Shock | Sepsis, Severe

Turkey
Rhode Island Hospital

Completed

Restrictive Intravenous Fluids Trial in Sepsis (RIFTS)

Septic Shock | Severe Sepsis

United States
Beth Israel Deaconess Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endothelium in Severe Sepsis

Sepsis | Septic Shock | Severe Sepsis

United States
Iuliu Hatieganu University of Medicine and Pharmacy

Unknown

Volemic Resuscitation in Sepsis and Septic Shock

Sepsis | Septic Shock | Hemodynamic Instability

Romania
Kompetenznetz Sepsis
Biosyn; Brahms AG

Completed

Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (SISPCT)

Septic Shock | Severe Sepsis

Germany
Sphingotec GmbH
Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Hopital... and other collaborators

Completed

Adrenomedullin and Outcome in Severe Sepsis and Septic Shock (AdrenOSS)

Septic Shock | Severe Sepsis

France, Belgium, Germany, Italy, Netherlands
SepNet - Critical Care Trials Group
Novo Nordisk A/S; German Federal Ministry of Education and Research; B. Braun... and other collaborators

Completed

Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)

Septic Shock | Severe Sepsis

Germany
Brahms AG

Completed

Procalcitonin Monitoring Sepsis Study (MOSES)

Septic Shock | Severe Sepsis

United States
AstraZeneca

Completed

A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic Shock

Septic Shock | Severe Sepsis

Japan
AstraZeneca

Completed

A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock

Septic Shock | Severe Sepsis

Czech Republic, France, Spain, Finland, Canada, Australia, Belgium
Teesside University

Unknown

Inferior Vena Cava Collapsibility Index in Severe Sepsis

Sepsis | Septic Shock | Severe Sepsis

United Kingdom
Hospital Sao Domingos

Unknown

Prognostic Evaluation Of Severe Sepsis And Septic Shock. Procalcitonin Versus Delta Sofa

Septic Shock | Severe Sepsis

Brazil
Institut Paoli-Calmettes

Completed

Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients (PROTEOHSEPS)

Sepsis | Cancer | Septic Shock

France
Rigshospitalet, Denmark
University of Copenhagen

Completed

Transcutaneous Electric Muscle Stimulation (TEMS) in Septic Patients

Septic Shock

Denmark
National Center for Research Resources (NCRR)
Children's Hospital Medical Center, Cincinnati

Completed

Diagnostic Study of Adrenal Cortical Function in Children With Septic Shock

Septic Shock

United States
University Hospital, Montpellier

Recruiting

Transient Circulatory Support in Cardiogenic Shock (ALLOASSIST)

Acute Cardiogenic Shock

France
Humanitas Clinical and Research Center

Not yet recruiting

Myocardial Work in Septic Shock Patients (MYWORKSS)

Critical Illness | Septic Shock

Italy
Children's Hospital of Fudan University
Chinese PLA General Hospital; Shengjing Hospital; Shanghai Children's Hospital; Beijing Children's Hospital and other collaborators

Recruiting

Study on the Efficacy and Timing of ECMO Therapy in Children With Refractory Septic Shock

Septic Shock | Extracorporeal Membrane Oxygenation Complication

China
University of Virginia

Terminated

Midodrine Use in Septic Shock

Septic Shock

United States
Hamad Medical Corporation

Terminated

Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock (HYVITS)

Critical Illness | Septic Shock

Qatar
Groupe Hospitalier Paris Saint Joseph
Assistance Publique - Hôpitaux de Paris; Institut Pasteur; BioMérieux

Completed

SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU (Captain)

Sepsis | Septic Shock | Severe Sepsis | SIRS

France
Chun Pan

Completed

Effects of Nursing Staff on Empiric Antibiotic in Septic Shock

Septic Shock | Nursing Caries | Antibiotic | Compliance
Grupo de Apoio ao Adolescente e a Crianca com Cancer

Unknown

Evaluation of Fluid Resuscitation in Children With Cancer With Severe Sepsis / Septic Shock

Cancer | Septic Shock | Other Fluid Overload

Brazil
D'Or Institute for Research and Education

Recruiting

Effects of Targets of Blood Pressure on Cerebral Hemodynamics in Septic Shock

Septic Shock | Cerebral Autoregulation

Brazil
The Cooper Health System

Active, not recruiting

Caretaker vs. Blood Pressure Monitoring With Invasive Arterial Pressure Monitoring in Patients With Septic Shock

Blood Pressure

United States
Tunis University

Completed

Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact

Sepsis | Septic Shock | Immunoinflammatory Response

Tunisia
Yale University

Withdrawn

Study of Low Carbohydrate Enteral Nutrition in Patients With Bacterial Septic Shock

Bacterial Sepsis

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Acute Intestinal Failure in Critically Ill Patients and Microbial Translocation (IGA-TM)

Septic Shock

France
Università Politecnica delle Marche

Completed

Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients.

Septic Shock | Severe Sepsis

Italy
Mahidol University
Siriraj Hospital

Completed

Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER)

Septic Shock | Severe Sepsis

Thailand
M.D. Anderson Cancer Center

Withdrawn

Early Metabolic Support as a Potential Solution to Multi-Organ Dysfunction Syndrome (MODS) During Severe Sepsis

Septic Shock
Federal University of Minas Gerais
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Completed

Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections

Septic Shock | Severe Sepsis

Brazil
Hadassah Medical Organization

Unknown

Early Goal-directed Therapy and Myocardial Dysfunction (SEPT-MD)

Sepsis | Septic Shock | Myocardial Dysfunction

Israel
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring

Septic Shock | Severe Sepsis

Brazil
Pharmazz, Inc.

Recruiting

A Study to Assess the Safety and Efficacy of Centhaquine in Hypovolemic Shock Patients

Hypovolemic Shock

India
Pharmazz, Inc.

Completed

Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock

Hypovolemic Shock

India
Federal University of Uberlandia

Unknown

Hemodynamic Measurements at Different Inclinations of the Head (HMDIH)

Hypovolemic Shock

Brazil
Mongi Slim Hospital

Unknown

Hemodynamic Optimisation Guided With Transcranial Doppler in Septic Shock

Trans Cranial Doppler Ultrasonography in Heamodynamic Optimisation in Septic Shock

Tunisia
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
Wake Forest University Health Sciences

Withdrawn

Digital Ischemia Reduction in Critically Ill Patients (DIR)

Cardiogenic Shock | Hypovolemic Shock | Digital Ischemia

United States
Region Skane

Completed

Norepinephrine Administration Through a Midline Catheter in an Intermediate Care Unit

Septic Shock | Hypotension and Shock | Norepinephrine Adverse Reaction

Sweden
Medical University of Graz

Recruiting

Resuscitative Endovascular Balloon Occlusion of the Aorta in Haemorrhagic Shock

Trauma Injury | Non-compressible Torso Hemorrhage

Austria

Clinical Trials on Refractory Shock

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