Clinical Trials on Refractory Partial Epilepsy in Canada

Total 669 results

The Hospital for Sick Children

Completed

Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging

Partial Epilepsy | Localization-related Epilepsy

Canada
University of Calgary

Unknown

Voronistat in Pediatric Patients With Drug Resistant Epilepsy

Refractory Epilepsy

Canada
McGill University

Recruiting

Using Micro-filaments to Detect "Fast Ripples" and Improve the Identification of the Epileptogenic Zone (NeuroSeizure)

Epilepsy, Refractory

Canada
The Canadian College of Naturopathic Medicine
University Health Network, Toronto; North York General Hospital; Ontario Brain...

Terminated

Clinical Trial of the Effects of DHA in the Treatment of Seizure Disorders

Epilepsy (Treatment Refractory)

Canada
Lawson Health Research Institute
UCB Pharma GmbH

Terminated

Lacosamide IV and EEG/EKG (LIVE) Study (LIVE)

Focal Epilepsy

Canada
University of Calgary
University of Alberta; University of Toronto; University of Western Ontario,... and other collaborators

Terminated

A Multicenter Study of Hippocampal Electrical Stimulation (HS, in Mesial Temporal Lobe Epilepsy (METTLE)

Temporal Lobe Epilepsy

Canada
Cyberonics, Inc.

Terminated

Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients

Epilepsy | Partial Epilepsy

Canada, Spain, Belgium, France, Germany, Italy, Netherlands, Norway, Sweden, United Kingdom
University of Calgary

Recruiting

Treating Postictal Symptoms Using Ibuprofen and Nifedipine

Epilepsy | Epilepsies, Partial

Canada
Bial - Portela C S.A.

Completed

Eslicarbazepine Acetate (BIA 2 093) as Therapy for Refractory Partial Seizures in Children

Partial Epilepsy in Children and Adolescents

United Kingdom, Spain, Serbia, Italy, Austria, Bosnia and Herzegovina, Croatia, Czechia, France, Germany, Hungary, Malaysia, Moldova, Republic of, Philippines, Poland, Portugal, Romania, Russian Federation, Slovakia, Taiwan, Ukr...
Supernus Pharmaceuticals, Inc.

Completed

Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy

Partial Epilepsy

United States, Poland, Bulgaria, Romania, Canada, Russian Federation, Mexico, Croatia
MedtronicNeuro

Completed

Product Surveillance Registry- Deep Brain Stimulation for Epilepsy (MORE)

Refractory Epilepsy

Belgium, Sweden, Austria, United Kingdom, Poland, Germany, Portugal, Canada, Finland, Hungary, Italy, Netherlands, Russian Federation
UCB Pharma SA

Completed

Study With Subjects 18-65 Years Old With Partial Onset Seizures Who Are Currently Taking Levetiracetam

Epilepsy, Partial

Canada, United States
Sunovion

Completed

Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs

Epilepsy With Simple or Complex Partial Onset Seizures

United States, Canada
Pfizer

Completed

Pregabalin Open-Label Extension Trial in Patients With Partial Seizures

Epilepsies, Partial | Epilepsy, Complex Partial

Spain, France, Canada, Germany, Italy, Lithuania, Austria, United Kingdom
Bial - Portela C S.A.
Sunovion

Completed

Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) as Adjunctive Therapy for Refractory Partial Seizures

Partial Epilepsy

United States, Argentina, Germany, France, Belgium, Canada, Italy, Poland, Greece, Brazil, Cyprus
Eisai Inc.

Completed

Dose Response Study of Zonegran in Patients With Newly Diagnosed Epilepsy

Epilepsy, Complex Partial

United States, Estonia, Ukraine, Hungary, Lithuania
Sunovion

Completed

Safety & Efficacy of Eslicarbazepine Monotherapy in Sub.w/Partial Epilepsy Not Well Controlled by Current Antiepileptic

Epilepsy

United States, Bulgaria, Czech Republic, Serbia, Ukraine
King's College London
King's College Hospital NHS Trust; The Hospital for Sick Children; Cardiff University and other collaborators

Completed

Rolandic Epilepsy Genomewide Association International Study (REGAIN)

Rolandic Epilepsy

United States, United Kingdom, Argentina, Canada, Greece, Italy, Spain
UCB Pharma

Completed

A 19-week Cognition Study of Levetiracetam in Children With Partial Onset Seizures

Epilepsy, Partial

United States, South Africa, Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open-Label Study Of Pregabalin In Subjects With Refractory Partial Seizures

Epilepsy

Canada
NYU Langone Health
The Epilepsy Study Consortium

Completed

The Human Epilepsy Project (HEP)

Focal Epilepsy

United States, Canada, Australia
UCB Pharma

Completed

Long-Term, Follow-Up Study Of the Safety And Efficacy Of Levetiracetam In Children With Partial Onset Seizures

Epilepsy, Partial

United States, France, United Kingdom, Germany, Belgium, Mexico, Poland, India, Romania, South Africa, Canada, Brazil, Russian Federation, Czech Republic, Hungary, Italy
UCB Pharma

Completed

A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.

Epilepsy, Partial

United States, France, United Kingdom, Germany, Belgium, Mexico, Poland, Romania, Canada, Brazil, Russian Federation, Argentina, Hungary, Italy, Czechia
Xenon Pharmaceuticals Inc.
Novotech Health Holdings Pte. Ltd.

Active, not recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy (X-TOLE)

Focal Epilepsy

Spain, United States, Ukraine, Canada, United Kingdom, Germany, Georgia, Italy, Moldova, Republic of
SK Life Science, Inc.

Completed

A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Partial Epilepsy

Australia, United States, Korea, Republic of, Germany, Hungary, Serbia, Bulgaria, Czechia, France, Israel, Poland, Romania, Spain, Thailand, Ukraine
SK Life Science, Inc.

Completed

Safety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Partial Epilepsy

United States, Spain, Korea, Republic of, Serbia, Germany, Bulgaria, Argentina, Australia, Chile, Czechia, Hungary, Mexico, Poland, Russian Federation, Sweden, Thailand, Ukraine
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Enrolling by invitation

An Open-label Study of XEN1101 in Epilepsy (X-TOLE4)

Focal Epilepsy | Tonic-Clonic Seizures

Spain, United States, Canada, Poland
Eisai Limited

Completed

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Idiopathic Generalized Epilepsy | Partial Onset Seizures | Generalised Tonic-Clonic Seizures

France, Spain, Italy, Denmark, Germany, Portugal, Russian Federation
University of British Columbia

Terminated

Flunarizine for Treatment Resistant Absence Epilepsy

Juvenile Myoclonic Epilepsy | Childhood Absence Epilepsy | Juvenile Absence Epilepsy

Canada
Pfizer

Completed

Evaluation of Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.

Seizure Disorder, Partial

Australia, Spain, Portugal, United Kingdom, Canada, Belgium, Germany, Poland, Netherlands, Austria
Sunovion

Completed

A Study of a Drug to be Used in Addition With Another Drug to Treat Adults With Uncontrolled Partial-onset Seizures

Epilepsy With Partial On-set Seizures

United States, Canada
UCB Pharma

Completed

Assess Safety and Efficacy of Lacosamide in Patients With Partial Seizures

Epilepsy

France, Poland, United Kingdom, Germany, Spain, Finland, Australia, Russian Federation, Hungary, Lithuania, Sweden, Czechia, Croatia
Pfizer

Completed

To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures

Seizure Disorder, Partial

United States, Canada
Eisai Inc.

Completed

Rufinamide Given as Adjunctive Therapy in Participants With Refractory Partial Seizures

Epilepsy

United States
The Hospital for Sick Children
St. Justine's Hospital

Completed

Deep Brain Stimulation Post Failed Vagal Nerve Stimulation (DBSpostVNS)

Epilepsy, Drug Resistant

Canada
University Health Network, Toronto

Unknown

Personalizing Health Outcome in Epilepsy Now - An Introduction to Clinical Services (PHOENICS)

Medically Intractable Epilepsy

Canada
Pfizer

Completed

To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.

Seizure Disorder, Partial

United States, Canada
Nova Scotia Health Authority

Not yet recruiting

Enhancing Epilepsy Management With Precision Deep Brain Stimulation (EPI-BOOST)

Epilepsy, Drug Resistant

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Topiramate as Adjunctive Therapy in Infants 1-24 Months for the Control of Partial Onset Seizures

Epilepsy | Seizures | Partial Seizure Disorder

United States, Australia, France, Belgium, Taiwan, Spain, Argentina, Poland, India, Ukraine, Finland, Korea, Republic of, Russian Federation, Chile, Thailand, Hungary, Israel, New Zealand, Canada, Mexico, Norway, Netherlands, South...
Eisai Inc.

Terminated

Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizures

Refractory Partial Onset Seizures

United States
Eisai Inc.

Completed

Evaluating the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Refractory Partial Seizures

United States, Chile, Brazil, Canada, Mexico, Argentina
Eisai Inc.

Completed

Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Refractory Partial Seizures

Hong Kong, Italy, Australia, Spain, Portugal, Taiwan, India, Thailand, Hungary, Poland, Bulgaria, Serbia, Russian Federation, Korea, Republic of, Ukraine, Romania, Latvia, Lithuania, Germany, Estonia, Czech Republic, Philippines, Ma...
University Health Network, Toronto

Withdrawn

Verapamil and Catamenial Epilepsy

Catamenial Epilepsy

Canada
Supernus Pharmaceuticals, Inc.
Parexel

Completed

Evaluation of Efficacy and Safety of OXC XR as Adjunctive Therapy for Partial Seizures (PROSPER1)

Epilepsies, Partial

United States, Poland, Mexico, Bulgaria, Romania, Canada, Russian Federation, Croatia
McGill University Health Centre/Research Institute...
The Scientific and Technological Research Council of Turkey

Not yet recruiting

Evaluating the Efficacy of a Mobile Epilepsy Education Application

Epilepsy | Anxiety | Knowledge, Attitudes, Practice | Epilepsy in Children

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Making Mindfulness Matter© in Children With Epilepsy (M3Epilepsy)

Quality of Life | Mindfulness | Epilepsy in Children

Canada
Lawson Health Research Institute
Ontario Brain Institute

Completed

Clinic to Community© Program for Adults With Epilepsy Admitted to Emergency Departments (C2CEDRCT)

Epilepsy, Generalized

Canada
Navigate Surgical Technologies Inc.

Completed

Study to Confirm Accuracy and Safety of the Inliant Surgical Navigation System

Partial Edentulism

Canada
British Columbia Children's Hospital

Recruiting

Role of the Gut Microbiota in Pediatric Epilepsy (EPBiome)

Drug Resistant Epilepsy

Canada
King's College London
King's College Hospital NHS Trust; Charles University, Czech Republic; Hopital... and other collaborators

Recruiting

Biology of Juvenile Myoclonic Epilepsy (BIOJUME)

Juvenile Myoclonic Epilepsy

United States, Canada, Czechia, Denmark, Estonia, France, Italy, Norway, United Kingdom

Clinical Trials on Refractory Partial Epilepsy in Canada

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