Clinical Trials on Renal Impairment in Hepatorenal Syndrome

Total 1672 results

National Hepatology & Tropical Medicine Research...

Completed

Norepinephrine Infusion Versus Midodrine & Octreotide in Patients With Hepatorenal Syndrome Type 1.

Renal Impairment in Hepatorenal Syndrome

Egypt
Vasopharm GmbH
Winicker Norimed GmbH

Completed

Effects of the NO-synthase Inhibitor VAS203 on Renal Function in Healthy Volunteers

Renal Function Impairment in Healthy Volunteers

Germany
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
UCB Pharma
Parexel

Completed

Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients

Healthy Subjects | Renal Impairments

Japan
Yuhan Corporation

Completed

A Study to Evaluate the Pharmacokinetics and Safety of YHD1119 in Subjects With Renal Impairment and Healthy Subjects

Healthy Volunteer | Renal Impairments

Korea, Republic of
Lahey Clinic
Beth Israel Deaconess Medical Center; Dr. Vikas Sukhatme

Terminated

Role Of Angiogenic Factors In The Development Of Hepatorenal Syndrome

Liver Diseases | Renal Failure | Hepatorenal Syndrome

United States
National Hepatology & Tropical Medicine Research...

Completed

Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal Syndrome

Hepato-Renal Syndrome

Egypt
Anna Cruceta

Withdrawn

Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure

Fibrosis | Renal Failure | Hepatorenal Syndrome

Spain
Ferring Pharmaceuticals

Completed

A Study of Terlipressin in Patients With Hepatorenal Syndrome Type 1 (HRS)

Hepatorenal Syndrome Type 1

Japan
Postgraduate Institute of Medical Education and...

Completed

Terlipressin Infusion Alone Vs Terlipressin With Noradrenaline Infusion In The Treatment of Hepatorenal Syndrome Type 1

Type 1 HEPATO RENAL SYNDROME(HRS)

India
Medical University of Vienna

Completed

Plasma and Hemodynamic Markers During Hepatectomy

Hepatorenal Syndrome, Liver Regeneration

Austria
Pere Gines

Unknown

Treatment of Hepatorenal Syndrome With Terlipressin Infusion Adjusted to Hemodynamic Response (AMELIORATE)

Cirrhosis | Hepatorenal Syndrome Type I

Spain
University of Padova

Unknown

Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome

Cirrhosis | Type 1 Hepatorenal Syndrome

Italy
La Jolla Pharmaceutical Company

Terminated

A Phase 1 Study of LJPC-501 in Patients With Hepatorenal Syndrome

Hepatorenal Syndrome Type I and Type II

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
University of Alberta
Novartis

Completed

The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction

Refractory Ascites | Type 2 Hepatorenal Syndrome

Canada
University Hospital Freiburg
University Hospital Muenster; Johannes Gutenberg University Mainz; Jena University...

Not yet recruiting

Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease (Terli-CKD)

Liver Cirrhosis | Chronic Kidney Diseases | Hepato-Renal Syndrome
Eisai Inc.

Completed

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Hepatic Impairment; Renal Impairment

United States
University Hospital Plymouth NHS Trust

Completed

RAI & HRS: Relationship Between Relative Adrenal Insufficiency and Failure of Treatment in Hepatorenal Syndrome

Liver Cirrhosis | Acute Kidney Injury | Hepato-Renal Syndrome

United Kingdom
Hvidovre University Hospital

Completed

MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI)

Liver Diseases | Cirrhosis | Acute Kidney Injury | Portal Hypertension | Liver Cirrhoses | Hepato-Renal Syndrome | Cirrhosis Cardiac

Denmark
University Hospital, Bonn

Recruiting

Non-invasive Evaluation of the Predictive Value of CEUS and SWE in ACLF, Renal Failure and Hepatorenal Syndrome (NECTAR)

Kidney Failure, Acute

Germany
University of Sao Paulo
Federal University of Rio Grande do Sul; University of Campinas, Brazil; Hospital... and other collaborators

Unknown

Study of Accuracy of NGAL, a Renal Injury Biomarker, in Patients With Cirrhosis

Acute Kidney Injury | Hepatorenal Syndrome

Brazil
Soonchunhyang University Hospital

Unknown

Korean Cohort Study of AKI & HRS in Cirrhosis

Liver Cirrhosis | Acute Kidney Injury | Hepatorenal Syndrome

Korea, Republic of
JW Pharmaceutical

Completed

A Safety, PK, PD and Food Effect Study of URC102 in Healthy Adults and Patients With Renal Impairment

Healthy, Renal Impairment

Korea, Republic of
Kowa Research Institute, Inc.

Completed

Safety, Tolerability, and Pharmacokinetic of Single Dose of Pitavastatin 4 mg in Severe Renal Patients Versus Healthy Adult Volunteers

Severe Renal Impairment

United States
Gilead Sciences

Terminated

A Phase 1 Study to Assess the Effect of Severe Renal Impairment on the Pharmacokinetics, as Well as Safety/Tolerability, of Ranolazine

Severe Renal Impairment

United States
Centre for Probe Development and Commercialization
St. Joseph's Healthcare Hamilton; McMaster University

Completed

A Single Centre Open Label Comparison of [I-123]-Ortho-Iodohippuric Acid (OIH) With [Tc-99m]-Mercaptoacetyltriglycine (MAG3) for Assessment of Renal Tubular Function

Renal Function Impairment

Canada
Sichuan Haisco Pharmaceutical Group Co., Ltd
The First Affiliated Hospital of Zhengzhou University

Completed

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions

Chronic Renal Impairment

China
Novartis Pharmaceuticals

Completed

Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Mild and Moderate Renal Impairment

Russian Federation, Germany, Serbia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Melbourne Health

Withdrawn

Frusemide Infusion for the Prevention of Deterioration in Renal Function Post Cardiac Surgery.

Renal Impairment After Cardiac Surgery

Australia
Hospices Civils de Lyon

Completed

Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury

Cirrhosis | Acute Kidney Injury | Hepatorenal Syndrome | Diastolic Function

France
Postgraduate Institute of Medical Education and...

Completed

TYPE 2 HEPATORENAL SYNDROME (Type2 HRS)

Safety and Efficacy of Terlipressin and Noradrenaline and Predictive Factors of Response in Type 2 HRS

India
River 2 Renal Corp.

Recruiting

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

Acute Kidney Injury | Hepatorenal Syndrome

United States
Oregon Health and Science University

Completed

Mindfulness Meditation for Subjects With Severe Speech and Physical Impairments (MSPi)

Cerebral Palsy | Physical Impairments | Cerebral Ataxia | locked-in Syndrome

United States
AstraZeneca

Completed

A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment

Renal Impairment | Hepatic Impairment

Bulgaria
Austin Health

Completed

Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study (BLISS)

Systemic Inflammatory Response Syndrome | Renal Impairment | Oliguria

Australia
Novartis Pharmaceuticals

Completed

An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects

Mild Moderate | or Severe Renal Impairment

Germany
Centre Hospitalier Universitaire de Saint Etienne
GlaxoSmithKline

Completed

Prospective, Multicentre, Open-label Study Evaluating 1.5 mg/Day of Fondaparinux. (PROPICE)

Major Orthopaedic Surgery and Renal Impairment

France
Mallinckrodt

Completed

Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

Hepatorenal Syndrome

United States, Canada
Patrick Northup, MD

Terminated

Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline

Hepatorenal Syndrome

United States
University of Louisville

Completed

Outcomes of Renal Function in Hepatorenal Syndrome (HRS) Determined By Comparison of Target Mean Arterial Pressure (MAP) of 65 - 70 Mmhg Versus ≥ 85 Mmhg

Hepatorenal Syndrome

United States
The University of Hong Kong
The Hong Kong Society of Nephrology

Unknown

Use of Novel Plasma and Urinary Biomarkers to Predict the Development of Hepatorenal Syndrome in Cirrhotic Patients

Hepatorenal Syndrome

Hong Kong
Cumberland Pharmaceuticals

Completed

Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients

Hepatorenal Syndrome

United States, India
Lenar Yessayan

Recruiting

The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I

Acute Kidney Injury | Hepatorenal Syndrome

United States
Mallinckrodt

Completed

Study of Terlipressin Versus Placebo to Treat Hepatorenal Syndrome Type 1

Hepatorenal Syndrome

United States
Institute of Liver and Biliary Sciences, India

Withdrawn

To Compare the Efficacy of Nor Adrenaline and Terlipressin vs Step up Terlipressin Therapy in Hepatorenal Syndrome

Hepatorenal Syndrome

India
Sun Yat-sen University

Unknown

The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial Pressure

Hepatorenal Syndrome

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir

Renal Impairment | Hepatic Impairment

China
Takeda

Completed

Phase I Open-label Study to Evaluate Pharmacokinetics of TAK-272 in Participants With Renal or Hepatic Impairment

Renal Impairment | Hepatic Impairment

Japan

Clinical Trials on Renal Impairment in Hepatorenal Syndrome

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