Clinical Trials on Respiration, Artificial in United Kingdom

Total 2508 results

Jeffrey Bluestone
National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance...

Terminated

Tregs for the Treatment of Acute Respiratory Distress Syndrome (ARDS) Associated With COVID-19 (regARDS) (regARDS)

Acute Respiratory Distress Syndrome Due to Disease Caused by 2019-nCoV

United States
Direct Biologics, LLC

Recruiting

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

Acute Respiratory Distress Syndrome | ARDS

United States
VA Office of Research and Development

Recruiting

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

Quality of Life | Obstructive Sleep Apnea | Elderly | COPD | Sleepiness | Sleep Apnea Syndrome | Neurocognitive Function | Overlap Syndrome | Positive Airway Pressure

United States
University of Maryland, Baltimore
Patient-Centered Outcomes Research Institute; McMaster University

Active, not recruiting

Pre-operative Alcohol Skin Solutions in Fractured Extremities (PREPARE)

Surgical Site Infection | Pelvic Fracture | Unplanned Fracture-Related Reoperation | Open Appendicular Fracture | Closed Lower Extremity Fracture

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) (EDEN)

Respiratory Distress Syndrome, Adult

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study) (EDEN-Omega)

Respiratory Distress Syndrome, Adult

United States
Janssen Research & Development, LLC
Bayer

Completed

A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients (MARINER)

Heart Failure | Rheumatic Diseases | Respiratory Insufficiency | Infectious Diseases | Stroke Acute

United States, Poland, Ukraine, United Kingdom, Germany, Spain, Argentina, Belarus, Colombia, Israel, Mexico, Portugal, Bulgaria, Romania, Serbia, South Africa, Turkey, Canada, Australia, Netherlands, Denmark, Greece, Peru, Brazil, Russian... and more
European Society of Anaesthesiology
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Local Assessment of Ventilatory Management During General Anesthesia for Surgery (LAS VEGAS)

Pneumonia | Pneumothorax | Anaesthesia | Respiratory Insufficiency | Surgery | Lung Injury | Ventilator-Induced Lung Injury | Respiratory Distress Syndrome, Adult

United States, Netherlands, Norway, Germany, Italy, Estonia, Slovenia, Lithuania
Family Health Centers of San Diego

Active, not recruiting

Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center? (LC&FIRP)

Chronic Fatigue Syndrome | SARS-CoV-2 Acute Respiratory Disease | Post COVID-19 Condition | Myalgic Encephalomyelitis | Post-acute Sequelae of SARS-COV-2 Infection

United States
Washington University School of Medicine

Completed

Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys (SATISFY-SOS)

Stroke | Pneumonia | Delirium | Respiratory Failure | Atrial Fibrillation | Deep Vein Thrombosis | Cardiac Arrest | Surgical Wound Infection | Stomach Ulcer | Pulmonary Embolism | Congestive Heart Failure | Nerve Injury | Angina | Respiratory Arrest | Heart Attack | Gastrointestinal Bleed

United States
NYU Langone Health
Daxor Corporation

Completed

Blood Volume Assessment in COVID-19 and Bacterial Sepsis (BVAC19)

Covid19 | Bacterial Infections | Acute Respiratory Distress Syndrome | Bacterial Sepsis

United States
Eli Lilly and Company

Completed

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Belgium, Spain, Canada, Australia, New Zealand
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Withdrawn

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure (IPGE1)

Streptococcal Infections | Respiratory Insufficiency | Pulmonary Hypertension | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
Altor BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome

Sepsis | Acute Respiratory Distress Syndrome | Acute Lung Injury

United States
NICHD Neonatal Research Network

Completed

Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome (Surfactant 1)

Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Cephalon

Completed

Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

Narcolepsy | Excessive Daytime Sleepiness | Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)

United States
Denver Health and Hospital Authority
University of Colorado, Denver; University of Miami; Beth Israel Deaconess Medical... and other collaborators

Completed

Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection

Severe Acute Respiratory Syndrome | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Sage Therapeutics

Terminated

A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19)

COVID-19 | Acute Respiratory Distress Syndrome

United States
Windtree Therapeutics

Completed

The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19)

COVID-19 | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

United States, Argentina
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy (SLEEP)

Obstructive Sleep Apnea of Adult | Preeclampsia | Obstetrical Complications

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Milrinone in Congenital Diaphragmatic Hernia

Persistent Pulmonary Hypertension of the Newborn | Congenital Diaphragmatic Hernia | Hypoxemic Respiratory Failure | Pulmonary Hypoplasia

United States
University of Minnesota
Bill and Melinda Gates Foundation

Completed

Losartan for Patients With COVID-19 Requiring Hospitalization

Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS-CoV Infection

United States
Dompé Farmaceutici S.p.A

Recruiting

Add-on Reparixin in Adult Patients With ARDS

Acute Respiratory Distress Syndrome, Adult

United States, Germany, Italy
Gordon Bernard

Terminated

STIP: Statin Trial for Influenza Patients (STIP)

Influenza | Acute Respiratory Distress Syndrome | H1N1 Influenza

United States
University Hospital, Clermont-Ferrand
Groupe Hospitalier Pitie-Salpetriere; University Hospital Schleswig-Holstein; Hospital Clínico Universitario de Valencia

Completed

Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) (ISCA)

Acute Respiratory Distress Syndrome | Sedation | Invasive Mechanical Ventilation | Critically Illness

United States, France, Spain, Germany, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Cord Blood-Derived Mesenchymal Stem Cells for the Treatment of COVID-19 Related Acute Respiratory Distress Syndrome

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | COVID-19 Infection | Symptomatic COVID-19 Infection Laboratory-Confirmed | COVID-19-Associated Acute Respiratory Distress Syndrome

United States
NeuroRx, Inc.

Recruiting

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 (AVICOVID-2)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI

United States
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors

COVID-19 | Coronavirus Disease 2019 | COVID-19 Pneumonia | COVID-19 Respiratory Infection | COVID-19 Acute Respiratory Distress Syndrome | COVID-19 Acute Bronchitis | COVID-19 Lower Respiratory Infection

United States
Metamorphosis LTD

Completed

Stellate Ganglion Block to Treat Long COVID 19 Case Series

Pain | Muscle Pain | Cough | Dizziness | Anosmia | Post-COVID-19 Syndrome | Dysautonomia | Post Acute COVID-19 Syndrome | Long COVID | Long Covid19 | Dysgeusia | Shortness of Breath | Menstrual Cycle Abnormal | Brain Fog | Fatigue Post Viral

United States
Montefiore Medical Center
University of California, Los Angeles; University of Michigan; Duke University

Completed

Severe ARDS: Generating Evidence (SAGE)

Acute Respiratory Distress Syndrome | Acute Respiratory Failure | Acute Respiratory Failure With Hypoxia

United States
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
ProgenaBiome

Completed

A Retrospective Study of COVID-19 Treatments

Covid19 | SARS-CoV2 Infection | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Respiratory Infection | COVID-19 Acute Respiratory Distress Syndrome | COVID-19 Acute Bronchitis | COVID-19 Lower Respiratory Infection

United States
The Geneva Foundation
Uniformed Services University of the Health Sciences; Brooke Army Medical Center and other collaborators

Recruiting

SARS-CoV-2/COVID-19 Study of Next Generation Non-Invasive Passive Detection Technologies (PassiveDetect)

COVID-19 | Influenza | Corona Virus Infection | COVID-19 Pneumonia | RSV Infection | COVID-19 Respiratory Infection | COVID-19 Acute Respiratory Distress Syndrome | SARS-CoV-2 Virus

United States
APR Applied Pharma Research s.a.
Lavin Consulting, LLC

Completed

Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure (COVID-AIV)

Acute Lung Injury | Corona Virus Infection | Acute Respiratory Distress Syndrome (ARDS) | Critical COVID-19 With Respiratory Failure

United States
Kinevant Sciences GmbH
Roivant Sciences, Inc.

Completed

A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)

COVID-19

United States
Cephalon

Completed

Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

Sleep Apnea Syndromes | Sleep Apnea, Obstructive | Narcolepsy | Shift-Work Sleep Disorder

United States, Russian Federation
Alexion Pharmaceuticals

No longer available

SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19

COVID-19 | Pneumonia, Viral | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

United States, France
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET)

Critical Illness | Vitamin D Deficiency | Acute Respiratory Distress Syndrome

United States
Cephalon

Completed

Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression

Obstructive Sleep Apnea | Major Depressive Disorder | Sleep Disorders | Dysthymic Disorder

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure (Preemie iNO)

Pneumonia | Sepsis | Hypertension, Pulmonary | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn | Respiratory Distress Syndrome (RDS)

United States
Massachusetts General Hospital

Completed

Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery (ASTER)

Sepsis | Critical Illness | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Arch Biopartners Inc.

Completed

LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)

Severe Acute Respiratory Syndrome | Acute Kidney Injury | COVID | Acute Respiratory Distress Syndrome | Sars-CoV2

United States, Turkey, Canada
Leidos Life Sciences
United States Department of Defense

Terminated

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (Addendum 2)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE) (SAVE)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Eli Lilly and Company

Recruiting

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight (TRIUMPH-2)

Obesity | Overweight | Obstructive Sleep Apnea | Type 2 Diabetes

Australia, United States, Mexico, Spain, India, Brazil, Romania, Taiwan, Argentina
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Safety of Diagnosis and Therapy in the Inpatient Setting (PSLL2-0)

Pneumonia | Sepsis | Delirium | Confusion | Hip Pain Chronic | Hypoxia | Back Pain | Vomiting | Abdominal Pain | Diarrhea | Cough | Asthma | Chest Pain | Neck Pain | Fever | Cellulitis | Syncope | Headache | Deep Vein Thrombosis | Venous Thromboembolism | Soft Tissue Infections | Failure to Thrive | COPD | Pulmonary Embolism | Dyspnea | Leg Pain | Mental... and other conditions

United States
University of Michigan
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Recruiting

Sleep for Stroke Management and Recovery Trial (Sleep SMART)

Stroke | Sleep Apnea, Obstructive | Ischemic Stroke | Sleep Apnea | Telemedicine | TIA | Randomized Clinical Trial | CPAP | Home Sleep Apnea Test | Multicenter Trial

United States
Vasomune Therapeutics, Inc.

Recruiting

Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.

Pneumonia, Viral | Pneumonia | Acute Respiratory Distress Syndrome | Respiratory Infection | COVID-19 Acute Respiratory Distress Syndrome | Viral or Bacterial Infections

United States
Debra Weese-Mayer
Children's Hospital of Philadelphia; Seattle Children's Hospital; Ann & Robert... and other collaborators

Recruiting

Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

Congenital Central Hypoventilation Syndrome | Congenital Central Hypoventilation | CCHS | CCHS With Hirschsprung Disease | CCHS With Neural Crest Tumor | CCHS With Neuroblastoma

United States

Clinical Trials on Respiration, Artificial in United Kingdom

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