Clinical Trials on Respiratory Conditions Due to Other External Agents

Total 1488 results

Assistance Publique - Hôpitaux de Paris

Completed

Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn (ANGIODYS)

Preterm Birth | Bronchopulmonary Dysplasia | Intra-uterine Growth Restriction | Maternal Preeclampsia

France
National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
Pfizer

Withdrawn

A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery

Pulmonary Embolism | Cerebral Stroke | Thrombosis, Deep Vein
Merrimack Pharmaceuticals
Sanofi

Completed

A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers

Colorectal Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Squamous Cell Head and Neck Cancer | Other Tumors With EGFR Dependence

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer

Kidney Cancer | Perioperative/Postoperative Complications | Urinary Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United States
National Cancer Institute (NCI)

Completed

Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM)

Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Tumors (Others)

United States
Cardiologie et Développement
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa (FEVRIER)

Heart Failure | Stroke | Syncope | Acute Coronary Syndrome | Deep Vein Thrombosis | Pericarditis | Endocarditis | Pulmonary Embolism | Conduction Abnormalities | Rhythm; Abnormal | Other Cardiovascular Conditions

Benin, Burkina Faso, Burundi, Cameroon, Congo, The Democratic Republic of the, Congo, Côte D'Ivoire, Gabon, Guinea, Mozambique, Niger, Senegal, Sudan
Massachusetts General Hospital
National Cancer Institute (NCI); American Cancer Society, Inc.

Completed

Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness

Cancer | Breast Cancer | Head and Neck Cancer | Schizophrenia | Lung Cancer | Bipolar Disorder | Major Depression | GI Cancer

United States
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
Centre Hospitalier Intercommunal Creteil
Groupe Français de Pneumo-Cancérologie

Terminated

Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases (METAL2)

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Cerebral Metastases | Adenocarcinoma of Lung Metastatic to Brain

France
Karolinska Institutet

Recruiting

Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia

Acute Kidney Injury | Pulmonary Hypertension | Congenital Diaphragmatic Hernia | Multiple Organ Failure | Hyperchloremia

Sweden
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
HiberCell, Inc.
Covance

Completed

A Study of HC-5404-FU to Establish the Maximum Tolerated Dose (MTD)

Renal Cell Carcinoma | Gastric Cancer | Metastatic Breast Cancer | Small-cell Lung Cancer | Other Solid Tumors

United States
Dr. Med Anas Taha
University of Basel; GZO Hospital, Zürich, Switzerland

Recruiting

Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)

Sleep Apnea, Obstructive | Diabetes Mellitus, Type 2 | Body Weight | Hiatal Hernia | Internal Hernia | GERD | Intussusception | Post-Op Complication | Anastomosis, Leaking | Mesenteric Hernia

Switzerland
University Hospital, Strasbourg, France

Recruiting

Impact of Covid-19 on Training for ENT and Cervico-Facial Surgery Residents in France

Cervico-Facial Surgery ENT Academic Medical and Surgical Training in France | Cervico-Facial Surgery ENT Medical Residency (Auvergne-Rhône-Alpes, Grand Est, Ile de France, Nouvelle Aquitaine and Provence-Alpes-Côte d'Azur Areas)

France
Dr. Sami Ulus Children's Hospital

Unknown

Fish Oil Supplementation in Women With Gestational Diabetes

Congenital Abnormality | Fetal Macrosomia | Other Respiratory Problems After Birth

Turkey
University of Pittsburgh
Patient-Centered Outcomes Research Institute

Active, not recruiting

PCORI Integrated Care (IC) Models for Patient-Centered Outcomes (IC)

Depression | Hypertension | Diabetes | Arthritis | Schizophrenia | Chronic Obstructive Pulmonary Disease | Atrial Fibrillation | Asthma | Anxiety | Bipolar Disorder | Congestive Heart Failure

United States
David Bartlett
National Cancer Institute (NCI)

Completed

αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies

Peritoneal Carcinomatosis | Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface | Malignant Peritoneal Mesothelioma

United States
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Terminated

A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Raynaud's Phenomenon Secondary to Systemic Sclerosis

United Kingdom, United States
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso

Pancreatic Cancer | Malignant Mesothelioma | Triple Negative Breast Cancer | Endometrial Cancer | Ovarian Tumor | Other Mesothelin Positive Tumors

China
Scynexis, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment (FURI)

Coccidioidomycosis | Invasive Pulmonary Aspergillosis | Allergic Bronchopulmonary Aspergillosis | Histoplasmosis | Chronic Pulmonary Aspergillosis | Blastomycosis | Invasive Candidiasis | Recurrent Vulvovaginal Candidiasis | Mucocutaneous Candidiasis | Other Emerging Fungi

United States, Spain, United Kingdom, Austria, Pakistan, South Africa, Germany, Netherlands
Instituto Nacional de Cancerologia de Mexico

Completed

Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients

Phase II Clinical Trial | Ninety-six Histologically Confirmed NSCLC Patients With BM | Randomized 1:1 to Received TN Plus WBR or Only WBR | ICPFS Evaluated by Two Blinded and Independent Radio-oncologist With MRI

Mexico
Centre Hospitalier Universitaire de Nice

Completed

Continous Renal Replacement Therapy With the CARPEDIEM® in a French National Cohort of 25 Neonates and Small Infants

Kidney Diseases | Sepsis | Pulmonary Disease | Hypoxic-Ischemic Encephalopathy | Cardiac Disease | Metabolic Disease | Twin to Twin Transfusion Syndrome

France
Massachusetts General Hospital
National Cancer Institute (NCI); Harvard Risk Management Foundation

Completed

Bridge: Proactive Psychiatry Consultation and Case Management for Patients With Cancer

Cancer | Breast Cancer | Head and Neck Cancer | Schizophrenia | Lung Cancer | Bipolar Disorder | Gastrointestinal Cancer | Severe Major Depression

United States
University of Latvia
Technion, Israel Institute of Technology; Riga East University Hospital; JLM...

Enrolling by invitation

Volatiles in Breath and Headspace Analysis - Diagnostic Markers (Volatolome)

Liver Cirrhosis | Inflammatory Bowel Diseases | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Peptic Ulcer | Tuberculosis | Pancreatitis, Chronic | Liver Cancer | Colorectal Adenoma | Intestinal Metaplasia | Colorectal Polyp | Gastric Dysplasia | Atrophic Gastritis | Other Infectious Diseases | Flu, Human

Latvia
Medway NHS Foundation Trust

Recruiting

Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes (ULOOP)

Hypoxic-Ischemic Encephalopathy | Admission to Neonatal Unit | Stillbirth | Small for Gestational Age at Delivery

United Kingdom
Joel Neal
Nektar Therapeutics

Completed

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Tumors Metastatic to Brain | Stage IV Non-small Cell Lung Cancer (NSCLC) | Recurrent Non-small Cell Lung Cancer (NSCLC) | Extensive-stage Small Cell Lung Cancer (SCLC) | Recurrent Small Cell Lung Cancer (SCLC) | Metastatic Breast Cancer (mBC)

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Maryland Cigarette Restitution Fund

Completed

Survivorship Promotion In Reducing IGF-1 Trial (SPIRIT)

Kidney Cancer | Breast Cancer | Pancreatic Cancer | Lung Cancer | Rectal Cancer | Prostate Cancer | Endometrial Cancer | Colon Cancer | Liver Cancer | Melanoma of Skin | Other Solid Malignant Tumors

United States
Mathematica Policy Research, Inc.
Centers for Medicare and Medicaid Services

Unknown

Evaluation of Programs of Coordinated Care and Disease Management (Coca)

Coronary Artery Disease | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Major Depression | Alzheimer's Disease | Congestive Heart Failure | Cerebrovascular Disease | Psychotic Disorder

United States
Neogene Therapeutics, Inc.

Recruiting

A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Breast Cancer | Pancreatic Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Colorectal Carcinoma | Other Solid Tumors

United States
AstraZeneca
PHARMO Institute for Drug Outcome Research

Completed

Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists

Pneumonia | Gastroenteritis | Seizures | Failure to Thrive | Hospitalized Cases of Angioneurotic Oedema | Acute Interstitial Nephritis and Thrombocytopenia

Netherlands
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Safety, Tolerability and Pharmacokinetics of Oral CPL304110, in Adult Subjects With Advanced Solid Malignancies

Sarcoma | Gastric Cancer | Cholangiocarcinoma | Bladder Cancer | Endometrial Cancer | Squamous Non-small Cell Lung Cancer | Other Solid Tumours

Poland
Kaiser Permanente
Garfield Memorial Fund

Completed

Multidisciplinary Inpatient Palliative Care Intervention

Liver Failure | Acquired Immunodeficiency Syndrome | Stroke | Pneumonia | Diabetes Mellitus | Cancer | Pulmonary Disease, Chronic Obstructive | Respiratory Failure | Renal Failure | Dementia | Kidney Failure, Chronic | Coronary Arteriosclerosis | Cerebrovascular Accident | Failure to Thrive | Heart Failure, Congestive

United States
Pfizer

Completed

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

NSCLC | SCCHN | Part 1 | MELANOMA | OVCA | SARCOMA | OTHER SOLID TUMORS | Part 1 and 2 | UROTHELIAL CARCINOMA

United States, Korea, Republic of, Russian Federation, Poland, Malaysia, Bulgaria, Ukraine
AstraZeneca

Completed

Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours

Ovarian Cancer, TNBC, SCLC, Other Solid Tumours

United States, Canada
Loxo Oncology, Inc.
Eli Lilly and Company

Available

Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation

Breast Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Colon Cancer | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Other Solid Tumors With Evidence of Activating RET Alteration

Spain, United States, Australia, France, Germany, Israel, Italy, Japan, New Zealand, Poland, Singapore, Switzerland
Denver Health and Hospital Authority

Completed

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

Pneumonia | Anesthesia, Local | Drug Effect | Opioid Dependence | Surgical Procedure, Unspecified | Rib Fractures | Local Infiltration | Nerve Pain | Rib Trauma | Pain; Catheter (Other) | Intercostal Rib | Chest Injury Trauma

United States
Thomas Jefferson University

Recruiting

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

Stroke | Cerebral Palsy | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Hemiparesis | Spinal Muscular Atrophy | Quadriplegia | Arthrogryposis | Neurologic Diseases | Charcot-Marie-Tooth | Weakness of Extremities as Sequela of Stroke | Weakness Due to Upper Motor Neuron Dysfunction | Arm Paralysis

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Epoetin Alfa in Treating Anemia in Patients Who Are Receiving Chemotherapy

Lymphoma | Leukemia | Breast Cancer | Chronic Myeloproliferative Disorders | Anemia | Small Intestine Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Genentech, Inc.
BioNTech SE

Active, not recruiting

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Melanoma | Head and Neck Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Renal Cancer | Other Solid Cancers

United States, Belgium, Sweden, Germany, Canada, Spain, United Kingdom, Netherlands
Quantgene Inc.

Unknown

Circulating Tumor DNA Exposure in Peripheral Blood

Melanoma | Breast Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Bladder Cancer | Non-small Cell Lung Cancer | Other Cancer | Adrenocortical Cancer

Switzerland, United States
PMV Pharmaceuticals, Inc
Merck Sharp & Dohme LLC

Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Metastatic Cancer | Advanced Solid Tumor | Endometrial Cancer | Metastatic Solid Tumor | Other Cancer | Advanced Malignant Neoplasm | Locally Advanced

United States, Spain, Korea, Republic of, Australia, France, Germany, Italy, Singapore, United Kingdom
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Safety of Diagnosis and Therapy in the Inpatient Setting (PSLL2-0)

Pneumonia | Sepsis | Delirium | Confusion | Hip Pain Chronic | Hypoxia | Back Pain | Vomiting | Abdominal Pain | Diarrhea | Cough | Asthma | Chest Pain | Neck Pain | Fever | Cellulitis | Syncope | Headache | Deep Vein Thrombosis | Venous Thromboembolism | Soft Tissue Infections | Failure to Thrive | COPD | Pulmonary Embolism | Dyspnea | Leg Pain | Mental... and other conditions

United States
Provectus Biopharmaceuticals, Inc.

Active, not recruiting

A Study to Assess PV-10 Chemoablation of Cancer of the Liver

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastatic Melanoma | Metastatic Uveal Melanoma | Metastatic Pancreatic Cancer | Metastatic Colon Cancer | Metastatic Ocular Melanoma | Cancer Metastatic to the Liver

United States
Massachusetts General Hospital
Trefler Foundation

Recruiting

Adapting the Tumor Board Model for Mental Illness and Cancer

Cancer | Breast Cancer | Head and Neck Cancer | Schizophrenia | Lung Cancer | Bipolar Disorder | Gastrointestinal Cancer | Genitourinary Cancer | Severe Major Depression

United States
National Cancer Institute (NCI)

Completed

Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic... and other conditions

United States
National Cancer Institute (NCI)

Terminated

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Unspecified Adult Solid Tumor, Protocol Specific | HER2-positive Breast Cancer | Recurrent Melanoma | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Recurrent Breast Cancer | Estrogen Receptor-negative Breast... and other conditions

United States
Russian Academy of Medical Sciences

Completed

Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome

Neurocognitive Disorders | Brain Ischemia | Delirium, Dementia, Amnestic, Cognitive Disorders | Organic Brain Syndrome, Nonpsychotic | Mental Disorder, Organic | Nonpsychotic Organic Brain Syndrome | Organic Mental Disorder | Encephalopathy, Post-Traumatic, Chronic | Encephalopathy, Ischemic

Russian Federation
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant

Juvenile Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Childhood Acute Myeloid Leukemia in Remission | Accelerated Phase Chronic Myelogenous Leukemia | Childhood Acute Lymphoblastic Leukemia in Remission | Childhood Chronic Myelogenous Leukemia | Childhood Myelodysplastic Syndromes and other conditions

United States

Clinical Trials on Respiratory Conditions Due to Other External Agents

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CROs in Saint Lucia

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