Clinical Trials on Respiratory Depression

Total 64644 results

Fusion Pharmaceuticals Inc.
AstraZeneca

Not yet recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Advanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal Carcinoma

United States, Canada
Helsinki University Central Hospital

Recruiting

Neuropsychological Rehabilitation Over the Internet (IRENE)

Encephalitis | Traumatic Brain Injury | Hypoxia-Ischemia, Brain | Brain Hemorrhage | Stroke, Acute Ischemic

Finland
Paul R Fortin
Canadian Institutes of Health Research (CIHR)

Recruiting

COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases (COVBIRD)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Systemic Vasculitis | Immunosuppression | Scleroderma | Autoimmune Rheumatologic Disease | Undifferentiated Connective Tissue Diseases | Overlap Connective Tissue Disease

Canada
Hospices Civils de Lyon

Recruiting

Impact of Telemonitoring for the Management of Side Effects in Patients With Melanoma, Lung or Renal Cancer, Treated With Immunotherapy Combination of Nivolumab and Ipilimumab or Adjuvant Nivolumab Monotherapy (MONITOR)

Melanoma | Lung Cancer | Renal Cancer

France
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; National Institute of General Medical... and other collaborators

Recruiting

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Melanoma | Sarcoma | Breast Cancer | Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Prostate Cancer | Skin Cancer | Healthy Volunteer | Colon Cancer | Gastrointestinal Cancer | Solid Tumor Cancer | Genitourinary Cancer

United States
Chongqing Precision Biotech Co., Ltd

Recruiting

Safety and Efficacy of CEA-Targeted CAR-T Therapy for Relapsed/Refractory CEA+ Cancer

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Solid Tumor | Liver Cancer

China
Turku University Hospital

Recruiting

Overcoming Chemoresistance in Advanced Ovarian Cancer Via Targeting Hypoxia (OVANOX)

Hypoxia | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Carcinoma

Finland
Agenus Inc.

Recruiting

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer

Melanoma | Ovarian Cancer | Prostate Cancer | Non-small-cell Lung Cancer | Endometrial Cancer | Advanced Cancer | Angiosarcoma | Fibrolamellar Carcinoma | Colorectal Cancer Without Liver Metastases

United States
Megan Daly, MD
Merck Sharp & Dohme LLC

Recruiting

UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade

Metastatic Renal Cell Carcinoma | Non Small Cell Lung Cancer | Metastatic Melanoma | Head and Neck Squamous Cell Carcinoma

United States
Novartis Pharmaceuticals

Completed

Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS) (DFV890-FCAS)

Familial Cold Autoinflammatory Syndrome

United States, France, Germany
Tomsk National Research Medical Center of the Russian...
Uppsala University; The Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry

Enrolling by invitation

Molecular Imaging of EpCAM Receptors Using [123I]I-DARPIN-Ec1

Ovarian Cancer | Lung Cancer

Russian Federation
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Preemie Hypothermia for Neonatal Encephalopathy

Hypoxia, Brain | Hypoxia-Ischemia, Brain | Hypoxic-Ischemic Encephalopathy | Infant, Newborn | Ischemic-Hypoxic Encephalopathy | Encephalopathy, Hypoxic-Ischemic

United States
Hellenic Institute for the Study of Sepsis
The BioArte

Completed

NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification (BIOARTE)

Pneumonia | Bacteremia | Acute Pyelonephritis | Biliary Tract Infection

Greece
Osijek University Hospital

Completed

Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia

Surgical Wound Infiltration | Chronic Shoulder Pain | Breast Cancer Female | Postoperative Analgesia | Lymph Node Dissection | Hand Strength | Health Related Quality of Life
Celgene

Completed

A Study of Special Use Results Surveillance of Revlimid 5mg Capsules

Myelodysplastic Syndromes | Multiple Myeloma

Japan
Instituto Nacional de Cancerologia de Mexico

Completed

Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients

Phase II Clinical Trial | Ninety-six Histologically Confirmed NSCLC Patients With BM | Randomized 1:1 to Received TN Plus WBR or Only WBR | ICPFS Evaluated by Two Blinded and Independent Radio-oncologist With MRI

Mexico
InSightec

Completed

ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain

Multiple Myeloma | Bone Metastases

United States, Canada, Israel, Italy, Russian Federation
Northwestern University
National Cancer Institute (NCI)

Terminated

Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel

Pain | Peripheral Neuropathy | Stage IV Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Chemotherapeutic Agent Toxicity | Therapy-related Toxicity

United States
Shandong University of Traditional Chinese Medicine

Unknown

Electrical Acupoint Stimulation for Postoperative Recovery (EAS)

Postoperative Complications | Postoperative Delirium | Deep Vein Thrombosis | Postoperative Infection | Postoperative Nausea and Vomiting | Postoperative Pneumonia | Postoperative Recovery | Postoperative Retention of Urine

China
GlaxoSmithKline

Terminated

Immuno & Safety Study With 2 Formulations of DTPw-HBV/HIB When Given at Birth With Hepatitis B at 2, 4 and 6 Mths.Age.

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis

Dominican Republic
Georgetown University

Completed

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

End Stage Renal Disease | Hyperhomocysteinemia

United States
Novartis Pharmaceuticals

Recruiting

A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced Cancers

Carcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung | Nasopharyngeal Carcinoma | Carcinoma, Ovarian Epithelial | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Anal Cancer | Cutaneous Melanoma | Esophagogastric Cancer | Carcinoma, Thymic | High Microsatellite...

Italy, Spain, Singapore, Germany, Taiwan, Japan, Canada, Hong Kong, United States
Nurix Therapeutics, Inc.

Recruiting

A Study of NX-1607 in Adults With Advanced Malignancies

Cervical Cancer | Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancer (NSCLC) | Metastatic Urothelial Carcinoma | Ovarian Cancer, Epithelial | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Triple Negative Breast Cancer (TNBC) | Malignant Pleural Mesothelioma... and other conditions

United States, United Kingdom
Hoffmann-La Roche

Active, not recruiting

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) (STARTRK-2)

Melanoma | Renal Cell Carcinoma | Adult Solid Tumor | Breast Cancer | Head and Neck Neoplasms | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Neuroendocrine Tumors | Lymphoma, Large-Cell, Anaplastic | Cholangiocarcinoma | Papillary Thyroid Cancer | Sarcomas | Salivary Gland Cancers and other conditions

United States, China, Korea, Republic of, Australia, Taiwan, France, Spain, United Kingdom, Hong Kong, Belgium, Italy, Germany, Japan, Singapore, Netherlands, Poland
Rahul Aggarwal
Xynomic Pharmaceuticals, Inc.

Completed

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Locally Advanced Melanoma | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients (TOASTIT)

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Rhabdomyosarcoma | Refractory Rhabdomyosarcoma | Recurrent Colon Carcinoma | Recurrent Gastric Carcinoma | Recurrent Rectal Carcinoma | Refractory Sarcoma | Refractory Ovarian Carcinoma | Resectable... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Recurrent Peritoneal Malignant Mesothelioma | Recurrent Pleural Malignant Mesothelioma | Vaginal Squamous Cell Carcinoma, Not Otherwise Specified | Neuroendocrine Carcinoma | Pancreatic Neuroendocrine Tumor | Recurrent Merkel Cell Carcinoma | Recurrent Nasopharynx Carcinoma | Appendix Adenocarcinoma and other conditions

United States
Chisquares Incorporated

Not yet recruiting

Collaborative Open Research Initiative Study (CORIS-1) (CORIS-1)

COVID-19 | Burnout, Professional | Patient Engagement | Artificial Intelligence | Substance Use Disorders | Mental Health Issue | Climate Change | Preventable Disease, Vaccine | Emerging Infectious Disease | Online Education
University of Zurich
ETH Zurich

Recruiting

Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics (COPE-CMR)

Non ST Elevation Myocardial Infarction | Myocarditis Acute | Takotsubo Cardiomyopathy | Spontaneous Coronary Artery Dissection | Myocardial Infarction With Non-Obstructive Coronary Artery

Switzerland
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Evaluation of Skin Health and QoL in Pts Receiving Anti-PD1/PDL1/CTLA4 or CDK Inhibitors. (SkinHealth)

Melanoma | Kidney Cancer | Breast Cancer | Gastric Cancer | Lung Cancer | Bladder Cancer | Skin Cancer | Head Neck Cancer

Italy
University of Edinburgh
NHS Lothian; Prism Training and Consultancy; Simpsons Special Care Babies

Recruiting

Investigating Cerebral Oxygenation in the Newborn (ICON)

Neonatal Encephalopathy | Premature Infant Disease | Hypoxic Ischemic Encephalopathy of Newborn

United Kingdom
Pfizer

Recruiting

A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors

Glioma | Melanoma | Colorectal Cancer | Brain Neoplasms | Non-Small Cell Lung Cancer | Thyroid Cancer | Malignant Neoplasms

Canada, United States
Duke University
Genzyme, a Sanofi Company

Recruiting

High Dose Inspiratory Muscle Training in LOPD

Late-Onset Pompe Disease | Lysosomal Disease

United States
Centre Georges Francois Leclerc

Recruiting

Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT) (IMMUNOs-SBRT)

Metastatic Renal Cell Carcinoma | Metastatic Non Small Cell Lung Cancer | Metastatic Head and Neck Cancer | Metastatic Bladder Cancer

France
HealthTree Foundation
GlaxoSmithKline

Recruiting

MGUS, SMM, and MM Patient Experience With Coronavirus 19 (COVID-19) Survey

Multiple Myeloma | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma | Coronavirus

United States
Universidad Politecnica de Madrid
Puerta de Hierro University Hospital; Hospital Vall d'Hebron; Hospital Severo... and other collaborators

Recruiting

Active Pregnancy Against COVID-19 (ACPREGCOV)

Pregnancy Complications | Pregnancy, High Risk | Maternal-Fetal Relations | Fetal Growth Retardation | Newborn Morbidity | Weight Gain, Maternal | Pregnancy Induced Hypertension | Fetus Disorder

Spain
MacroGenics

Terminated

MGC018 With or Without MGA012 in Advanced Solid Tumors

Melanoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Metastatic Castrate Resistant Prostate Cancer | Advanced Solid Tumor, Adult

Spain, United States, Australia, Poland
Incyte Corporation

Terminated

Study of INCB086550 in Select Solid Tumors

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Urothelial Cancer

Korea, Republic of, Bulgaria, Hungary, Taiwan, Ukraine
Imperial College London

Completed

Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs

Hereditary Hemorrhagic Telangiectasia | Pulmonary Arteriovenous Malformations

United Kingdom
The Cleveland Clinic

Active, not recruiting

A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery

Malnutrition | Esophageal Cancer | Lung Cancer | Frail Elderly Syndrome | Sarcopenia | Surgery | Surgery--Complications | Thoracic Neoplasm | Thoracic

United States
Albert B. Sabin Vaccine Institute
ICON plc; Oklahoma Blood Institute

Completed

Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults

Ebola Virus Disease | Marburg Virus Disease

United States
University of Pittsburgh

Completed

COVID-19 Brain Injury

Ischemic Stroke | Traumatic Brain Injury | Subarachnoid Hemorrhage | Hemorrhagic Stroke | Intracerebral Hemorrhage | Status Epilepticus | Sars-CoV2 | Severe Neurologic Injury

United States
Novartis Pharmaceuticals

Completed

Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations

Cancer

France, Australia, United States, Canada, United Kingdom
M.D. Anderson Cancer Center
Centers for Medicare and Medicaid Services

Completed

Cancer Prevention and Treatment Demonstration for Ethnic and Racial Minorities

Cervical Cancer | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer

United States
Centers for Disease Control and Prevention
Bill and Melinda Gates Foundation; Ministry of Health, Uganda; African Field... and other collaborators

Completed

Evaluating a Caregiver SMS Reminder Intervention to Reduce Immunization Drop-out in Arua, Uganda

Hepatitis B | Measles | Pertussis | Tetanus | Diphtheria | Polio | Haemophilus Influenzae Type b Infection
National Defense Medical Center, Taiwan

Completed

Effects of Biofeedback in Patients With Acute Cerebral Infarction

Psychological Distress | Acute Ischemic Stroke | Biofeedback | Autonomic Dysfunction, Cognitive Function
GlaxoSmithKline

Completed

Safety Study of a Vaccine Against Meningitis in Infants (2,4 & 6 Months Age) After a Birth Dose of Hepatitis B.

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis

Thailand
Christian Kern

Unknown

Severe and Transient Hypoxemia During Selective Intra-arterial Chemotherapy for Retinoblastoma in Children: Evaluation of the Right-sided Heart Function.

Retinoblastoma

Switzerland
GlaxoSmithKline

Completed

Immunogenicity & Safety Study of a Vaccine Against Meningitis in Infants (2,4,6 Months) After a Hepatitis B Birth Dose.

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis

Thailand
GlaxoSmithKline

Completed

Assess if Immune Response of GSK Biologicals' Tritanrix™-HepB/Hib-MenAC Given Without or With Hepatitis B Vaccine at Birth is at Least as Good as Tritanrix™-HepB/Hiberix™ Without Hepatitis B Vaccine at Birth, When Given to Healthy Infants

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis

Philippines

Clinical Trials on Respiratory Depression

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Costa Rica

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations