Clinical Trials on Revision of Total Hip Arthroplasty in South Africa

Total 56 results

Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Amgen

Completed

Effect of Denosumab on Inflammatory Osteolytic Lesion Activity in Total Hip Arthroplasty

Revision Surgery of Total Hip Arthroplasty

United Kingdom
VA Office of Research and Development

Recruiting

Effects of tDCS Combined With CBI on Postsurgical Pain (tDCS-CBI)

Total Knee Arthroplasty (Postoperative Pain) | Total Hip Arthroplasty (Postoperative Pain)

United States
VA Office of Research and Development

Completed

Dose Dependent Effects of tDCS on Post-Operative Pain (tDCS-TKA)

Total Knee Arthroplasty (Postoperative Pain) | Total Hip Arthroplasty(Postoperative Pain)

United States
Exactech

Recruiting

Optetrak Knee System Post Market Clinical Follow-Up

Knee Arthroplasty, Total

United States
Smith & Nephew, Inc.

Active, not recruiting

Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts (Legion Oxinium)

Total Knee Arthroplasty

United States
Exactech

Recruiting

A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System

Knee Arthroplasty, Total

United States
Zimmer Biomet

Recruiting

G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study

Osteoarthritis, Hip | Avascular Necrosis of Hip | Total Hip Arthroplasty | Osteoarthritis of Hip | Fracture of Hip | Degenerative Joint Disease of Hip | Fractures, Hip | Rheumatoid Arthritis of Hip

Denmark, United States, Sweden, Netherlands, United Kingdom
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
Pacira Pharmaceuticals, Inc

Terminated

Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in Subjects Undergoing TKA

Total Knee Arthroplasty

United States
Medical University of South Carolina

Completed

Total Hip Arthroplasty Outcomes With Regional and Multimodal Analgesia (THA)

Arthritis | Arthroplasty | Replacement, Hip

United States
Brown University

Completed

Schools Championing Safe South Africa

Prevention or Reduction of HIV Risk Behavior | Prevention or Reduction of Intimate Partner Violence

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
Stryker Orthopaedics

Completed

Accolade® TMZF® Hip Stem Outcomes Study

Arthroplasty, Replacement, Hip

United States
Bayer

Completed

FactOr XIa inhibiTion for the pRevention of venOus Thromboembolism in Patients Undergoing Total Knee Arthroplasty (FOXTROT)

Knee Arthroplasty, Total

Lithuania, Spain, Bulgaria, Israel, Poland, Czechia, Greece, Russian Federation, Latvia, Portugal, Ukraine, Canada, South Africa
Encore Medical, L.P.

Completed

Reverse Shoulder Prosthesis Study (RSP)

Rotator Cuff Arthropathy | Failed Total Shoulder | Failed Hemi-arthroplasty

United States
Zimmer Biomet

Completed

A Study to Compare the NexGen LPS and LPS-Flex Knee Implants

Osteoarthritis | Total Knee Arthroplasty

United States, Canada
University of Cape Town

Completed

Study of Hip and Knee Arthroplasty in South Africa

Arthritis, Rheumatoid | Osteoarthritis, Knee | Osteoarthritis, Hip | Arthritis Knee | Arthritis of Hip

South Africa
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
University of Vermont

Completed

Mobile Technology to Support Physical Therapy Exercise (MyTherEx)

Osteoarthritis of Knee | Osteoarthritis Of Hip

United States
CoolSystems, Inc.

Unknown

Use of Cold and Compression Therapy With Total Knee Replacement Patients

Osteoarthritis | Total Knee Arthroplasty

United States, Australia
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
University of Cape Town
King's College London; University of KwaZulu

Completed

Collaborative Care for the Detection and Management of Depression Among Adults Receiving Antiretroviral Therapy in South Africa (COBALT)

Depression | HIV/AIDS | Chronic Diseases of Lifestyle

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
Regenesis Biomedical, Inc.

Completed

Pilot Study of PEMF Therapy in Treatment of Post-operative Pain Following Total Knee Arthroplasty

Post-Operative Pain Following Total Knee Arthroplasty

United States
Boehringer Ingelheim

Completed

Dabigatran Etexilate in Extended Venous Thromboembolism (VTE) Prevention After Hip Replacement Surgery

Thromboembolism | Arthroplasty, Replacement, Hip

Australia, Austria, Belgium, Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, Netherlands, Norway, Poland, South Africa, Spain, Sweden
Medical University of South Carolina

Completed

Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash

Arthropathy of Knee | Arthropathy of Hip

United States
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
Astellas Pharma Europe B.V.

Completed

A Study Evaluating Efficacy and Safety of YM150 Compared to Enoxaparin in Subjects Undergoing Hip Replacement Surgery (ONYX-3)

Venous Thromboembolism | Arthroplasty, Replacement, Hip

Denmark, Spain, United States, Austria, Colombia, Russian Federation, India, Italy, United Kingdom, Germany, Hungary, Estonia, Romania, South Africa, Israel, Poland, Sweden, Canada, Australia, Lithuania, Ukraine, Latvia, Finland, Brazil, Slovak... and more
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
Medical University of South Carolina

Completed

Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty

Arthropathy of Hip

United States
The Hawkins Foundation

Completed

Hip Scope Fascia-iliaca (FI) Block Study

Acetabular Labrum Tear | Hip Dysplasia | Femoroacetabular Impingement

United States
Foundation for Innovative New Diagnostics, Switzerland
Swiss Tropical & Public Health Institute; University of Cape Town; The HIV Netherlands... and other collaborators

Completed

FujiLAM Prospective Evaluation Trial

Diagnosis of Tuberculosis in People Living With HIV

Malawi, South Africa, Tanzania, Thailand, Uganda, Vietnam, Zambia
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
Pfizer

Completed

Efficacy and Safety of a Subcutaneous Tanezumab Titration Dosing Regimen in Subjects With Moderate to Severe Osteoarthritis of the Hip or Knee

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Puerto Rico, Canada
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Arthrex, Inc.

Recruiting

Web Based Orthopaedic Sports Medicine Registry

Degenerative and Traumatic Pathology of the Knee | Degenerative and Traumatic Pathology of the Shoulder and Elbow | Degenerative and Traumatic Pathology of the Foot and Ankle | Degenerative and Traumatic Pathology of the Hand and Wrist | Degenerative and Traumatic Pathology of the Hip

United States, United Kingdom, Canada, Puerto Rico, South Africa
Pfizer

Completed

Tanezumab in Osteoarthritis of the Hip or Knee (2)

Osteoarthritis

United States
Zimmer Biomet

Active, not recruiting

Persona Partial Knee Clinical Outcomes Study

Osteoarthritis | Avascular Necrosis | Traumatic Arthritis | Conditional Tibial Condyle or Plateau Fractures | Conditional Revision of the Articular Surface

United Kingdom, Spain, United States, Italy, Sweden, Belgium, Austria, France, Germany, Switzerland
Arrevus Inc.

Terminated

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

Prosthetic Joint Infections of Hip | Prosthetic Joint Infections of Knee | Infected Spacers

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom
University of the West of Scotland
Swansea University

Completed

The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach

To Assess the Impact of the HIT Intervention on Physiological Responses | To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours | To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth

United Kingdom
University of Washington
National Cancer Institute (NCI)

Completed

Cisplatin and Radiation Therapy With or Without Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Nasopharynx | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous... and other conditions

United States
Abbott Medical Devices
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Baim Institute...

Completed

XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort (XVU-AV DAPT)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Terminated

Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee (FACT CLBP 1)

Osteoarthritis | Chronic Low Back Pain

United States
Novartis Pharmaceuticals

Completed

Ext. Long-term Safety Study in CF Patients: Single Arm TIP

Long-term Safety of TIP

Italy, Spain, Germany, United States, Australia, Canada, Hungary, Mexico, Argentina
University of Arizona
National Cancer Institute (NCI)

Completed

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

Head and Neck Cancer | Recurrent Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | HNSCC | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma | Stage IVA Nasal Cavity and... and other conditions

United States
Gilead Sciences

Active, not recruiting

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection (PURPOSE 2)

Pre-Exposure Prophylaxis of HIV Infection

United States, Thailand, Brazil, Peru, Argentina, South Africa, Mexico, Puerto Rico
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Buccal Mucosa Squamous Cell Carcinoma | Floor of Mouth Squamous Cell Carcinoma | Gingival Squamous Cell Carcinoma | Hard Palate Squamous Cell Carcinoma | Lip Squamous Cell... and other conditions

United States, Canada
National Cancer Institute (NCI)
NRG Oncology

Suspended

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Stage... and other conditions

United States

Clinical Trials on Revision of Total Hip Arthroplasty in South Africa

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