Clinical Trials on Rheumatic

Total 9832 results

Merck Sharp & Dohme LLC
Centocor, Inc.

Completed

Real Life Dosing of Remicade for Rheumatoid Arthritis in Austria Monitored Over 9 Infusions (Study P03756)(COMPLETED)

Rheumatoid Arthritis
Bristol-Myers Squibb

Withdrawn

Pharmacokinetic Study to Compare the Blood Levels of Low vs High Metal Manufacture of Abatacept

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) Given Subcutaneously in Combination With Traditional DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United States, Colombia, Brazil, Canada, South Africa, Spain, Greece, Russian Federation, Switzerland, Thailand, Bulgaria, Israel, Mexico, Hungary, Argentina, Panama, Philippines, Guatemala, Malaysia, Australia, New Zealand
Bristol-Myers Squibb

Completed

Methotrexate-Inadequate Response Autoinjector Device Sub Study (MTX-IR)

Rheumatoid Arthritis
Assistance Publique Hopitaux De Marseille

Completed

Impact of Adalimumab Therapy on Brachial Endothelial Function and Large Artery Stiffness in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Austria
Gilead Sciences

Completed

Safety, Tolerability, and Pharmacokinetics of GS-5745 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary, Czech Republic
Chong Kun Dang Pharmaceutical

Unknown

Efficacy and Safety Study of Mizoribine in Active Rheumatoid (AMOLED) (AMOLED)

Rheumatoid Arthritis

Korea, Republic of
University of California, Los Angeles

Completed

Ultrasound Scores as Indication of Response to Subcutaneous Abatacept in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
University of Glasgow
NHS Lothian; NHS Tayside; NHS Grampian; Arthritis Research UK; NHS Fife; NHS Borders

Completed

Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy (ORBIT)

Rheumatoid Arthritis

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Oral Prednisone in Patients With Rheumatoid Arthritis (MK0000-088)

Rheumatoid Arthritis
Vertex Pharmaceuticals Incorporated

Completed

A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor

Rheumatoid Arthritis

United States, Denmark, Estonia, Lithuania, Netherlands, South Africa
Hanmi Pharmaceutical Company Limited

Completed

Safety,PK/PD, Food Effect Study of Orally Administered HM71224 in Healthy Adult Male Volunteers

Rheumatoid Arthritis

Netherlands
Rheumazentrum Ruhrgebiet

Completed

Diagnostic Value of Oral Prednisolone Test for Rheumatoid Arthritis (TryCort)

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Colombia, Costa Rica, Mexico, Ecuador, Brazil, Argentina, Chile, Venezuela, Peru, Uruguay
Pfizer

Completed

Long-Term, Open-Label Study Of CP-690,550 For Treatment Of Rheumatoid Arthritis In Japan

Rheumatoid Arthritis

Japan
Ronald J. Rapoport, MD
Mallinckrodt

Unknown

Addition of H.P. Acthar Gel to Treatment Regimen of Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Bristol-Myers Squibb

Completed

Phase IIIB Subcutaneous Missed Dose Study

Rheumatoid Arthritis

Argentina, Mexico, United States, South Africa, Canada
Pfizer

Completed

Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Mexico, Argentina, Chile, Croatia, Czech Republic, Hungary, Poland, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate (SCORE)

Rheumatoid Arthritis

Germany, Spain, Switzerland, Canada, Estonia, Greece, France, Russian Federation, Netherlands, Turkey, Serbia, Argentina, Latvia, Lithuania, Denmark, Romania, Brazil, Czech Republic, Norway
Bristol-Myers Squibb

Completed

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, United States, Argentina, Brazil, Canada, Mexico, Peru, Korea, Republic of, Sweden, Australia, Russian Federation, Poland, Puerto Rico, Czech Republic, Denmark, South Africa, Switzerland
Plexxikon

Withdrawn

Safety, Pharmacokinetic (PK), Pharmcodynamic (PD), and Drug-Drug Interaction of PLX3397 in Patients With Rheumatoid Arthritis Who Are Receiving Methotrexate

Rheumatoid Arthritis

United States
Rüdiger B. Müller
Bristol-Myers Squibb

Completed

Introducing a Single IV Abatacept Treatment in RA Patients Currently Receiving Weekly SC Abatacept to Simulate a Holiday (A-BREAK)

Rheumatoid Arthritis

Switzerland
Biotest

Completed

Dose-finding of Multiple Dose of BT061 in Patients With Active Rheumatoid Arthritis Incompletely Controlled on Stable Methotrexate (MTX)

Rheumatoid Arthritis

Poland, Czech Republic, Germany, Hungary, Italy, Latvia, Spain
Bangor University

Unknown

Can Creatine Supplementation Improve Body Composition and Physical Function in Rheumatoid Arthritis Patients?

Rheumatoid Arthritis

United Kingdom
National Institute of Arthritis and Musculoskeletal...
University of Alabama at Birmingham

Completed

Consortium for the Longitudinal Evaluation of African Americans With Early Rheumatoid Arthritis (The CLEAR Registry) (CLEAR)

Rheumatoid Arthritis

United States
Singapore General Hospital

Terminated

Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study

Rheumatoid Arthritis

Singapore
Hoffmann-La Roche

Completed

A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.

Rheumatoid Arthritis

United Kingdom
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) in Combination With DMARDs Versus Current Best Practice DMARD Therapy in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Finland
Hoffmann-La Roche

Completed

A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies.

Rheumatoid Arthritis

Korea, Republic of
Hoffmann-La Roche

Completed

A Study Comparing Infusion Rates of Tocilizumab in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
American College of Rheumatology

Unknown

Rheumatology Clinical Registry (RCR)

Rheumatoid Arthritis

United States
Astellas Pharma Inc

Completed

A Double Blind Placebo Controlled Study to Assess the Efficacy on Joint Damage in RA Patients

Rheumatoid Arthritis

Japan
Pfizer

Completed

Study to Assess the Safety and Efficacy of Etanercept in Patients Treated Over the Long-term in Real-world Clinical Practice, Using Data Collected by the British Society of Rheumatology Biologics Registry

Rheumatoid Arthritis
Hoffmann-La Roche

Completed

A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Agents.

Rheumatoid Arthritis

Taiwan
Amgen
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

CAMEO: Canadian Methotrexate and Etanercept Outcome Study

Rheumatoid Arthritis

Canada
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs (REMISSION)

Rheumatoid Arthritis

Morocco
AstraZeneca

Terminated

Randomised Double-Blind, Placebo-Controlled, Parallel Group Study in Patients With Active Rheumatoid Arthritis:Magnetic Resonance Imaging Sub-Study (OSKIRA 4 SS)

Rheumatoid Arthritis

United States, Bulgaria, Russian Federation, South Africa, United Kingdom, Germany, Hungary, Netherlands, Canada, Czech Republic, Poland
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Non-biologic DMARDs

Rheumatoid Arthritis

Indonesia
Molecular Research Center, Inc.
Harrison Clinical Research; Camargo Pharmaceutical Services; Clin Data Services; BARC Global Central Laboratory and other collaborators

Unknown

A Study of Two Doses of MRC375 in Moderate to Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis

United States
AstraZeneca

Completed

Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid Arthritis (Oskira ABPM)

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Poland, South Africa, Ukraine, Germany
AstraZeneca

Terminated

Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA) (OSKIRA -4)

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Poland, Russian Federation, South Africa, United Kingdom, Hungary, Ukraine, Germany, Netherlands, Canada, Slovakia
AstraZeneca

Completed

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding. (OSKIRA - 2)

Rheumatoid Arthritis

United States, Czech Republic, Spain, United Kingdom, Latvia, Lithuania, Romania, Ukraine, Canada, Israel, Portugal, Germany, South Africa, Serbia, India, Italy
AstraZeneca

Completed

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist (OSKIRA - 3)

Rheumatoid Arthritis

United States, Czech Republic, Mexico, South Africa, Spain, United Kingdom, Germany, Argentina, Belgium, Canada, Hungary, Israel, Portugal, France, Brazil, Italy
AstraZeneca

Terminated

Evaluation of Safety and Effectiveness of Fostamatinib Compared to Placebo in Patients in Asia With Rheumatoid Arthritis (OSKIRA-Asia-1)

Rheumatoid Arthritis

Korea, Republic of, Vietnam, Hong Kong, Japan, Taiwan, Thailand
AstraZeneca

Terminated

A Long Term Study to Assess the Safety of Fostamatinib in Patients in Asia With Rheumatoid Arthritis (OSKIRA-Asia-1X)

Rheumatoid Arthritis

Korea, Republic of, Vietnam, Hong Kong, Taiwan, Thailand, Japan
AbbVie (prior sponsor, Abbott)

Completed

A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA) (MUSICA)

Rheumatoid Arthritis

United States, Puerto Rico
UCB Pharma

Completed

Magnetic Resonance Image Verified Early Response to Certolizumab Pegol in Subjects With Active Rheumatoid Arthritis (RA) (MARVELOUS)

Rheumatoid Arthritis

Denmark, Netherlands, Poland, Sweden
Antares Pharma Inc.

Completed

Exposure Study Comparing 3 Routes of Methotrexate (MTX) Administration

Rheumatoid Arthritis

United States
Postgraduate Institute of Medical Education and...

Completed

Study of Different Doses of Folic Acid in Combination With Methotrexate in Rheumatoid Arthritis (FOLVARI)

Rheumatoid Arthritis

India

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