Clinical Trials on Safety and Tolerability in Healthy Volunteers

Total 1166 results

Regeneron Pharmaceuticals

Not yet recruiting

Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants

Healthy Volunteers
Brown University
National Institute of Mental Health (NIMH)

Recruiting

Cognitive Control & the Functional Organization of the Frontal Cortex

Healthy Volunteers | Executive Function | Multitasking Behavior and Neural Representations Associated With Multitasking Ability

United States
National Institute of Mental Health (NIMH)

Completed

Identifying Decision Making Parameters in Healthy Volunteers and Anxiety Patients

Anxiety | Healthy Volunteers

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Healthy Volunteers | Influenza Immunization

United States
Korea University Guro Hospital
Korean Center for Disease Control and Prevention

Active, not recruiting

Safety, Reactogenicity, and Immunogenicity Study of Heterologous Booster Vaccination of a SARS-CoV-2 Recombinant Protein Nanoparticle Vaccine (GBP510)

COVID-19 (Healthy Volunteers)

Korea, Republic of
Assistance Publique - Hôpitaux de Paris
Sorbonne University; Université de Technologie de Compiegne

Completed

Device Evaluating the Muscular Functional Age (CHRONOS)

Healthy Volunteers | Skeletal Muscle

France
National Institute of Allergy and Infectious Diseases...

Terminated

Use of Labeled Glucose to Study Lymphocyte Replication and Survival in HIV-Infected Patients

HIV | Healthy Volunteers

United States
Genentech, Inc.

Completed

A Study to Investigate the Relative Bioavailability of Entrectinib Capsule Formulations F1 and F06 Under Fed Conditions in Healthy Participants

Healthy Volunteers

United States
Bayer

Completed

Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate

Healthy Volunteers | Pharmacokinetics | Drug Interaction

Germany
Asan Medical Center

Unknown

A Clinical Trial to Evaluate Pharmacokinetics of Daewon DW-ES(A) 625mg/5ml, Daewon DW-ES(B) 625mg/5ml and Megace 800mg/20ml in Healthy Male Volunteers Under Fed Condition

Healthy Volunteers
Panacea Biotec Ltd

Completed

Bioequivalence Study of Tacrolimus 5 mg Capsule Under Fed Condition

Healthy Volunteers

India
Hoffmann-La Roche

Completed

A Study to Assess the Impact of Speed and Site of Subcutaneous Injection on Pain, Tolerability, Safety, and Pharmacokinetics of Gantenerumab in Healthy Participants

Healthy Volunteer

United States
AstraZeneca

Completed

The Purpose of the Study is to Compare Two Fixed Dose Combination Tablets of Dapagliflozin/Metformin XR in Healthy Subjects Under Fasting and Fed Conditions

Healthy Subjects in Fasted and Fed State

Brazil
AstraZeneca

Completed

A Phase I, Open-Label, Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide in Healthy Chinese Participants

Healthy Volunteers

China
Insmed Incorporated

Completed

A Study to Investigate Lung Deposition of Inhaled Amikacin-loaded Liposomes in Healthy Male Participants

Healthy Volunteers
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers

Healthy Volunteers

Poland
Alexza Pharmaceuticals, Inc.

Completed

ADASUVE 2-dose Thorough QT/QTc Study

Healthy Volunteers

Netherlands
RWTH Aachen University

Terminated

Influence on Erythropoetin-level by Xenon (XEPO)

Healthy Volunteers

Germany
Mannkind Corporation

Completed

Comparison of 30 Units of TI (Technosphere® Insulin) Prepared With Insulin From Two Different Suppliers

Healthy Volunteers

United States
Pfizer

Completed

Multiple Dose Healthy Volunteer Study of PF-03715455. (MD-MULTI DOSE)

Healthy Volunteers

Singapore
AstraZeneca

Completed

AZD8683 Single Ascending Dose Study

Healthy Volunteers

United States
Pharmaxis

Completed

A Pharmacokinetic and Bioavailability Study of Mannitol for Inhalation Using Normal Subjects

Healthy Volunteers
AbbVie

Completed

A Study to Assess the Adverse Events and How Oral ABBV-552 Capsules Moves Through the Body of Healthy Adult Japanese and Han Chinese Participants

Healthy Volunteers

United States
The Affiliated Hospital of Qingdao University

Unknown

Bioequivalence of Oral Formulations of Anastrozole in Healthy Chinese Volunteers Under Fed Condition

Healthy Volunteers

China
Galmed Pharmaceuticals Ltd
Kramer Consulting, LLC; WCCT Global; Diamond Pharma Services Regulatory Affairs... and other collaborators

Completed

Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol Administered Under Fed Conditions in Healthy Chinese Volunteers

Healthy Volunteers

United States
Panacea Biotec Ltd

Completed

Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule Under Fed Condition

Healthy Volunteers

India
Panacea Biotec Ltd

Completed

Bioequivalence Study of Cyclosporine 100mg Capsule Under Fed Condition

Healthy Volunteers

India
University of Miami
Sherman Fairchild Foundation

Completed

Translational Health After School Program on Health-Related Knowledge/Behaviors and Exercise Perception (THINK)

Changes in Physical Fitness | Changes in Diet, Food, and Nutrition Habits | Changes in Child Health

United States
AstraZeneca
Parexel

Recruiting

A Placebo-controlled Safety and Tolerability Study of Intravenous (IV) and Subcutaneous (SC) AZD1163 in Healthy Volunteers

Healthy Volunteers

United States, Germany
Centre Hospitalier Universitaire de Saint Etienne

Completed

Effects of Running Shoe Sole Hardness on Vibration and Neuromuscular Fatigue During a Half-marathon Run on a Treadmill (FAT-VIB)

Healthy Volunteers

France
X-pert Med GmbH

Completed

UVB Model Validation Study

Pain | Inflammation | Healthy Volunteers

Germany
Pfizer

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04629991 in Healthy Volunteers

Healthy Volunteers

Belgium
National Institute of Mental Health (NIMH)

Recruiting

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Healthy Volunteer | Brain Mapping

United States
Amgen

Completed

Effect of Denosumab on Cellular Biomarkers in the Human Breast

Healthy Volunteer, Female, Breast

United States
University Health Network, Toronto

Completed

Comparing Head and Neck Endoscopy Procedures

Comparing Head And Neck Endoscopy in Healthy Patients

Canada
Bristol-Myers Squibb

Completed

A Study to Investigate the Effects of BMS-986278 on Drospirenone and Ethinyl Estradiol Drug Levels in Healthy Female Participants

Healthy Volunteers

Canada
Kutahya Health Sciences University

Completed

Inspiratory Muscle Endurance of Adults

Healthy Volunteers

Turkey
Orion Corporation, Orion Pharma

Completed

Absorption of Indacaterol and Glycopyrronium From Ultibro Breezhaler (FINDA)

Healthy Volunteers

Finland
Oxford Brookes University

Unknown

Aerosol Particle Size and Breathing Pattern During Inhaled Furosemide (FurAH-II)

Healthy Volunteers

United Kingdom
MedImmune LLC

Completed

Phase 1, Single Dose Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of MEDI5884

Healthy Volunteers

United States
AstraZeneca

Completed

AZD5423 Single Ascending Dose Study

Healthy Volunteers

United Kingdom
Mannkind Corporation

Completed

Compare the Same Dosage of Insulin Using a Combination of Cartridges, 30 Units as 2 Cartridges vs. 1 Cartridge

Healthy Volunteers

United States
University of Chicago

Completed

Patient Satisfaction and Safety Outcomes After Enrollment in a Same-Day (SD) Percutaneous Coronary Intervention Program

To Evaluate Clinical Outcomes, Safety, and Satisfaction of Patients Who Have Participated in a Same Day Outpatient Percutaneous Coronary Artery Intervention

United States
Queen Mary University of London
King's College London

Withdrawn

Brain Effect of Vagal Nerve Stimulation at Rest and Pain

Healthy Volunteer

United Kingdom
The Hospital for Sick Children

Recruiting

Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases

Healthy Volunteers

Canada
Biomind Labs Inc.
Universidade Federal do Rio Grande do Norte

Completed

Clinical Study of DMT in Healthy Adults

Healthy Volunteers

Brazil
GH Research Ireland Limited

Completed

Pharmacokinetics of GH001 in Healthy Volunteers

Healthy Volunteers

Netherlands
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study Comparing Tiotropium Easyhaler® and Spiriva® HandiHaler® (TESSA)

Healthy Volunteers

Finland
AstraZeneca

Completed

Multiple Ascending Doses (MAD) of AZD3199 Given Once Daily as Inhaled Formulation Via Turbuhaler to Healthy Men (AZD3199MAD)

Healthy Volunteers

Sweden
Mannkind Corporation

Completed

Pharmacokinetic Study in Healthy Volunteers

Healthy Volunteers

United States

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