Clinical Trials on Secondary Amyloidosis

Total 1930 results

M.D. Anderson Cancer Center

Completed

Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden

Multiple Myeloma | Primary Amyloidosis

United States
Alnylam Pharmaceuticals

Completed

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Polyneuropathy | Hereditary Transthyretin-mediated (ATTRv) Amyloidosis

United States
Bio Products Laboratory

Completed

A Study of the Safety and Efficacy of Vigam® Liquid in Patients With Primary or Secondary Antibody Deficiency

Primary or Secondary Antibody Deficiency

United Kingdom
University of Pennsylvania
Washington University School of Medicine

Completed

Escitalopram Effects on CSF Amyloid Beta

Amyloid Beta Protein

United States
GlaxoSmithKline

Terminated

Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging

Amyloidosis

Sweden
Sanofi

Active, not recruiting

Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis

Secondary Hyperparathyroidism-Chronic Kidney Disease

United States, Chile
Amgen

Completed

Extension Study of Cinacalcet for Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Patients With Chronic Kidney Disease on Dialysis

Secondary Hyperparathyroidism, Chronic Kidney Disease

United States, Czechia, Germany, France, Hungary, Greece, Belgium, Italy, Poland, Russian Federation, Ukraine
Amgen

Terminated

Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis

Chronic Kidney Disease, Secondary Hyperparathyroidism

United States, Belgium, Italy, Hungary, Czechia, France, Germany, Greece, Spain, Poland, Russian Federation, Ukraine, New Zealand, Slovakia, Lithuania, Portugal
Amgen

Completed

A Single-dose Study in Paediatric Patients Aged 2 to Less Than 18 Years With Secondary Hyperparathyroidism (sHPT) Receiving Haemodialysis

Chronic Kidney Disease, Secondary Hyperparathyroidism

Belgium, United States, Germany, Poland, United Kingdom, Lithuania
Istanbul University - Cerrahpasa (IUC)

Active, not recruiting

Longitudinal Changes in Left and Right Ventricular Global Strain After Chemotherapy in Cardiac Light Chain Amyloidosis

Chemotherapy Effect | Congestive Heart Failure | Amyloid Cardiomyopathy

Turkey
Poitiers University Hospital
Baxter Healthcare Corporation

Completed

Comparison of Hemodialysis With Medium Cut-off Dialyzer (Theranova) and High Flux Dialyzer (THERANOVA)

End Stage Renal Disease | Dialysis Related Complication | Dialysis Amyloidosis

France
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic Amyloidosis

Multiple Myeloma | Plasma Cell Myeloma

United States
Boston University
National Institute of Neurological Disorders and Stroke (NINDS); Food and Drug...

Completed

The Effect of Diflunisal on Familial Amyloidosis

Familial Amyloid Polyneuropathy | Familial Amyloidosis

United States, Italy, Japan, Sweden, United Kingdom
Genzyme, a Sanofi Company

Completed

A Phase 4, Conversion Study of Hectorol® Injection to Hectorol® Capsules in Stage 5 CKD Patients on Dialysis

Secondary Hyperparathyroidism

United States
Skane University Hospital
Karolinska University Hospital

Completed

Morbidity Related to Secondary Hyperparathyroidism After Renal Transplantation (SHPT-RT)

Secondary Hyperparathyroidism | Disorder Related to Renal Transplantation
Cliniques universitaires Saint-Luc- Université...
Frederic Thys,MD,PhD

Withdrawn

HERMES STUDY: Study on the Feasibility and Efficiency of Noninvasive Positive-Pressure Ventilation (NPPV) in Prehospital Care

ARF Secondary to COPD Exacerbation | ARF Secondary to Cardiogenic Acute Pulmonary Oedema

Belgium
Pfizer

Completed

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology (TTRACK)

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Italy, Romania, France, Australia, Austria, Portugal, Slovakia, Slovenia, Spain, United Kingdom
Amgen

Recruiting

A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis

Secondary Hyperparathyroidism

Spain, Belgium, Germany, Czechia, Poland, France, Greece, Hungary, Italy, United Kingdom, Lithuania, Portugal
Genzyme, a Sanofi Company

Completed

A Phase 4 Study to Determine Dosing of Hectorol® Capsules When Converting From Zemplar® Injection

Secondary Hyperparathyroidism

United States
GlaxoSmithKline

Withdrawn

Pro-arrhythmic Potential of GSK3039294 in Healthy Subjects

Amyloidosis

United Kingdom
Amgen

Completed

Post Transplant Study

Hyperparathyroidism | Secondary Hyperparathyroidism | Kidney Tansplant
Johannes Kepler University of Linz

Recruiting

Comparison of Two Different Intraocular Lenses Implanted With Yamane Technique

Aphakia | Secondary Cataract Surgery | Complicated Cataract Surgery

Austria
Inland Norway University of Applied Sciences
Montebellosenteret, Mesnali, Norway

Completed

Effect of Lifestyle Intervention vs Physical Therapy Treatment in Patients With Secondary Lymphedema After Cancer

Lymphedema, Secondary

Norway
Astellas Pharma Inc

Completed

A Study to Evaluate the Effect of ASP7991 in Secondary Hyperparathyroidism Patients Undergoing Hemodialysis

Secondary Hyperparathyroidism

Japan
Wenzhou Medical University

Completed

Treatment of Malignant Glaucoma by Anterior Vitrectomy From Two Different Approaches

Glaucoma Secondary
OPKO Health, Inc.

Completed

Pharmacokinetics and Safety Study of CTAP101 Capsules in Japanese and Non-Japanese Healthy Subjects and Non-Japanese Healthy Subjects

Secondary Hyperparathyroidism | Vitamin D Insufficiency

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Microwave Ablation With Splenic Artery Occlusion for Secondary Hypersplenism

Secondary Hypersplenism

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Study of Lung Function in Children Who Have Undergone Bone Marrow Transplantation

Long-term Effects Secondary to Cancer Therapy in Children | Pulmonary Complications

United States
Massachusetts General Hospital
Pfizer; Akcea Therapeutics; Alnylam Pharmaceuticals; Eidos Therapeutics, a BridgeBio...

Recruiting

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF (TTRinHFpEF)

Heart Failure | Amyloidosis | Heart Failure, Diastolic | Transthyretin Amyloidosis

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Low-Dose Melphalan and Dexamethasone Compared With High-Dose Melphalan Followed By Autologous Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Lenalidomide, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
Herlev Hospital

Recruiting

Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour (HEAL)

Episiotomy; Dehiscence | Dehiscence Wound | Secondary Perineal Tear

Denmark
National Center for Research Resources (NCRR)

Completed

Acute Regulation of Parathyroid Hormone by Dietary Phosphate

Secondary Hyperparathyroidism

United States
Washington University School of Medicine

Completed

Sleep Quality and Amyloid-Beta Kinetics

Amyloid-beta

United States
Beneficência Portuguesa de São Paulo

Recruiting

Increasing Amyloidosis Awareness and Diagnosis Through Programmatic Imaging, Blood/Urine Testing and Pathology

Amyloidosis

Brazil
Kerstyn C. Zalesin, M.D.
Abbott

Completed

Trial Of Paricalcitol and Cholecalciferol(Vitamin D3) in the Treatment Of Secondary Hyperparathyroidism in Patients After ROUX-EN-Y Gastric Bypass Surgery (ExtenD)

Gastric Bypass | Parathyroid Hormone

United States
Dent Neuroscience Research Center

Withdrawn

Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant

Clopidogrel Resistance | Secondary Stroke Prevention

United States
Ministry of Health, Saudi Arabia

Not yet recruiting

The Study of Quadruple Therapy Intranasal Insulin, Zinc, Gabapentin, Ice Cube Stimulation for Post COVID-19 Smell and Taste Dysfunctions (COVID-19)

Taste Disorders | Smell Disorder | Smell Dysfunction | Taste Disorder, Secondary, Sweet | Taste Disorder, Secondary, Bitter
Philippe Debonnaire

Not yet recruiting

Early Diagnosis of Age-Linked CArdiac TransThyRetin Amyloidosis by Selective Screening in Spinal Stenosis Surgery (ALCATTRASS)

Transthyretin Amyloid Cardiomyopathy
Montefiore Medical Center

Terminated

Cinacalcet to Treat Hypercalcemia in Renal Transplant Recipients

Secondary Hyperparathyroidism | Hypercalcemia

United States
Haukeland University Hospital
University of Bergen

Completed

Tissue Characterisation by Endoscopic GI-elastography

Secondary Malignant Neoplasm of Lymph Node | Disorder of Upper Gastrointestinal Tract | Pancreatic Nodule | Secondary and Unspecified Malignant Neoplasm of Retroperitoneal Lymph Nodes

Norway
Antisoma Research

Unknown

Phase III Randomized Study of Amonafide (AS1413) and Cytarabine Versus Daunorubicin and Cytarabine in Patients With Secondary Acute Myeloid Leukemia (AML)- the ACCEDE Study

Secondary Acute Myeloid Leukemia (Secondary AML, sAML)

Korea, Republic of, United States, Spain, United Kingdom, Australia, Austria, Taiwan, Israel, Italy, Belgium, Germany, France, Romania, Estonia, Canada, Ukraine, Ecuador, Hungary, Poland, Chile, Argentina, Czech Republic, Russian Federation
Octapharma

Completed

The Effect of Subcutaneous Immunoglobulin Gammanorm on the Distribution of IgG Subclasses and on Immunity of Patients With Secondary Immunodeficiency

Secondary Immune Deficiency

France
Henry Ford Health System

Recruiting

Carpal Tunnel Release With Risk Factors for Amyloidosis

Amyloidosis

United States
Mayo Clinic

Completed

Long-term Outcomes of Patients With Primary Amyloidosis After Stem Cell Transplantation

Amyloidosis

United States
Amgen

Completed

Compare the Efficacy of Cinacalcet vs Traditional Vitamin D for Secondary Hyperparathyroidism (SHPT) Among Subjects Undergoing Hemodialysis

Hyperparathyroidism, Secondary
KAI Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism

Hyperparathyroidism, Secondary

United States, Australia
Repros Therapeutics Inc.

Completed

The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)

Secondary Hypogonadism

United States
Repros Therapeutics Inc.

Completed

Study to Evaluate the Safety and Efficacy of Androxal™ Treatment in Men With Secondary Hypogonadism

Secondary Hypogonadism

United States
Repros Therapeutics Inc.

Completed

Phase III Study to Evaluated Morning Testosterone Normalization in Men With Secondary Hypogonadism

Secondary Hypogonadism

United States

Clinical Trials on Secondary Amyloidosis

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