Clinical Trials on Sepsis, Endotoxemia, Immunosuppression in Ireland

Total 54 results

Rachael Cusack
Grifols Biologicals, LLC

Recruiting

Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock

Sepsis | Septic Shock | Sepsis, Severe

Ireland
Rhode Island Hospital

Completed

Restrictive Intravenous Fluids Trial in Sepsis (RIFTS)

Septic Shock | Severe Sepsis

United States
Rhode Island Hospital

Recruiting

Assessment for Implementation Methods in Sepsis (AIMS)

Septic Shock | Sepsis Severe

United States
The Miriam Hospital

Recruiting

De-resuscitation Informed by Ultrasound for Patients With Sepsis (DRI-US)

Sepsis | Septic Shock | Sepsis, Severe | Volume Overload

United States
Anders Perner
Rigshospitalet, Denmark; University of Copenhagen; B. Braun Melsungen AG; Copenhagen...

Completed

Scandinavian Starch for Severe Sepsis/Septic Shock Trial (6S)

Septic Shock | Severe Sepsis

Denmark, Norway, Finland, Iceland
University College Dublin
Wellcome Trust; Health Research Board, Ireland; National Maternity Hospital,... and other collaborators

Recruiting

Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants (PARENT)

Late-Onset Neonatal Sepsis | Necrotising Enterocolitis | Culture Negative Neonatal Sepsis

Ireland
Inotrem

Active, not recruiting

Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock (ASTONISH)

Shock, Septic

Belgium, France, Spain, Denmark, Finland, Ireland
Institute for the Care of Mother and Child, Prague...
Coombe Women and Infants University Hospital

Completed

Does Routine Assessment of Gastric Residuals in Preterm Neonates Influence Time Taken to Reach Full Enteral Feeding? (GRASS)

Prematurity | Necrotizing Enterocolitis of Newborn | Sepsis Newborn | Gastric Residuals Assessment

Ireland, Czechia
Children's Hospital of Philadelphia
M.D. Anderson Cancer Center; The Hospital for Sick Children; Eunice Kennedy Shriver... and other collaborators

Recruiting

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PRoMPT BOLUS)

Shock | Septic

United States
Eli Lilly and Company

Completed

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Sepsis

Italy, United Kingdom, United States, Germany, Spain, Belgium, France, Australia, Czech Republic, Netherlands, Canada, Mexico, New Zealand, Finland, Portugal, Brazil, India, Switzerland
The Adelaide and Meath Hospital, incorporating...

Withdrawn

Percutaneous Nephrostomy Versus Stent In Sepsis Trial (PERSIST)

Sepsis | Hydronephrosis | Ureteric Calculus

Ireland
Belfast Health and Social Care Trust
Queen's University, Belfast; Royal College of Emergency Medicine; Pediatric Emergency... and other collaborators

Completed

Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. (PIC)

Sepsis | Meningitis, Meningococcal | Meningitis | Meningococcal Infections | Meningococcal Disease | Meningococcal Sepsis

United Kingdom
Beaumont Hospital

Unknown

Randomised Controlled Trial of Needle Free Access Devices in Preventing Hemodialysis Blood Stream Infection (TEGO)

Central Line Infection | Hemodialysis Catheter Blood Stream Infection | Dialysis Line Thrombosis

Ireland
Children's Cancer and Leukaemia Group

Unknown

Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter

Infection

United Kingdom, Ireland
University of Rhode Island
National Institute of Nursing Research (NINR); Brown University; Women and Infants...

Completed

Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants

Sepsis | Intraventricular Hemorrhage

United States
Belfast Health and Social Care Trust
University of Toronto; Queen's University, Belfast

Completed

Role of Active Deresuscitation After Resuscitation-2 (RADAR-2)

Sepsis | Critical Illness | Trauma

United Kingdom
Immunexpress
Rhode Island Hospital

Terminated

The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS

Sepsis | SIRS

United States
Belinda Howe
Australian and New Zealand Intensive Care Society Clinical Trials Group; Australasian...

Unknown

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)

Severe Sepsis

New Zealand, Australia, Finland, Ireland, Hong Kong
Tufts Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Salivary Profiling in Infants Treated for Suspected Sepsis: The SPITSS Study (SPITSS)

Infection; Newborn

United States
Mount Sinai Hospital, Canada
The Hospital for Sick Children; Sunnybrook Health Sciences Centre; University... and other collaborators

Recruiting

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

Late-Onset Neonatal Sepsis | Neonatal Hypotension | Extreme Prematurity

Canada, United States, Ireland, Israel
Abionic SA
Avania

Completed

Evaluation of Immunoassay Measurements of Pancreatic Stone Protein Performed on abioSCOPE® Device With the PSP Assay on ICU Patients at Risk of Sepsis as an Aid in Identifying Sepsis

Sepsis

United States
University of Rhode Island
National Institute of Nursing Research (NINR); Thrasher Research Fund

Completed

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Necrotizing Enterocolitis | Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Motor Skills Disorders | Late Onset Neonatal Sepsis

United States
T2 Biosystems

Completed

T2Bacteria Panel Pivotal Study (T2Bacteria)

Bacteremia

United States
Agennix

Completed

Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis

Severe Sepsis

United States, Canada, France, Germany, Spain
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Early-Onset Sepsis an NICHD/CDC Surveillance Study (EOSII)

Infant, Newborn, Diseases | Early Onset Neonatal Sepsis | Early-Onset Meningitis

United States
Brahms AG

Terminated

Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection

Sepsis | Infection | Bacterial Infection

United States
T2 Biosystems

Completed

Serial Therapeutic and Antifungal Monitoring Protocol (STAMP)

Candidemia

United States
Agennix

Suspended

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis (OASIS)

Severe Sepsis

United States, Spain, Belgium, France, United Kingdom, Canada, Israel, Germany, Denmark, Netherlands
Brown University

Recruiting

Using Telehealth to Address Alcohol Misuse in HIV Care (ReACH3)

Alcohol Drinking | HIV Viremia

United States
Biosite

Withdrawn

Multi-marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET) (MINDSET)

Sepsis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Pleconaril Enteroviral Sepsis Syndrome

Enterovirus Infection

United States, Canada
Eisai Inc.

Completed

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

Severe Sepsis

United States, France, Poland, United Kingdom, Germany, Hong Kong, Taiwan, Spain, Switzerland, Argentina, Belgium, Israel, South Africa, Japan, Canada, Netherlands, Korea, Republic of, Australia, Chile, Brazil, Austria, Italy, Czechia, Portug...
Cheetah Medical Inc.

Completed

Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Severe Sepsis (COMMIT)

Sepsis

United States
Cheetah Medical Inc.

Completed

Fluid Responsiveness Evaluation in Sepsis-associated Hypotension (FRESH)

Sepsis | Hypotension

United States, United Kingdom
Revalesio Corporation

Completed

Feasibility Study to Evaluate the Safety of Topically Applied Revera in Subjects With Venous Leg Ulcers

Venous Stasis Ulcers

United States
Eli Lilly and Company

Completed

A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis

Sepsis

United States, Poland, Belgium, Netherlands, Hungary
GlaxoSmithKline

Completed

GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults

Sepsis

United States, Canada, France, Netherlands, Russian Federation, Taiwan, Czechia, Estonia, Spain, Sweden, Thailand, Germany, Belgium, Israel, United Kingdom, Korea, Republic of, Portugal, Finland, Latvia, New Zealand, Malaysia, South... and more
AM-Pharma

Terminated

(Revival) Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI

Acute Kidney Injury Due to Sepsis

Belgium, Spain, United States, Austria, Denmark, France, United Kingdom, Finland, New Zealand, Australia, Germany, Canada, Netherlands, Ireland, Japan
Mayo Clinic

Completed

The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)

Sepsis | Shock | Critical Illness | Respiratory Failure | Bleeding | Trauma | Coma

China, Brazil, Belarus, Serbia, India, Turkey, Bosnia and Herzegovina, Croatia, Dominican Republic, Ireland, Mexico, Mongolia, Pakistan, Philippines, Poland, Saudi Arabia, Uganda
University of Alberta
Alberta Health services

Recruiting

Optimizing the Management of Staphylococcus Aureus Bacteremia (OPTIMUS-SAB)

Staph Aureus Bacteremia

Canada
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants (Glutamine)

Sepsis | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
AlloVir

Completed

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

BK Virus Infection | BK Virus Nephropathy

United States
Scynexis, Inc.

Completed

Oral Ibrexafungerp (SCY-078) vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasis

Mycoses | Candidemia | Candidiasis, Invasive

United States, El Salvador, Germany, Guatemala, Honduras
Armata Pharmaceuticals, Inc.
United States Department of Defense

Recruiting

Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia (diSArm)

Bacteremia | Staphylococcus Aureus | Staphylococcus Aureus Bacteremia | Bacteremia Due to Staphylococcus Aureus | Bacteremia Staph

United States, Australia
C. R. Bard

Terminated

The Pristine Post-Market Study

End Stage Renal Disease | Kidney Failure, Chronic | Hemodialysis Access Failure | Hemodialysis Complication | Central Venous Catheter Related Bloodstream Infection | Hemodialysis Catheter Infection

United States
Scynexis, Inc.

Suspended

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole (MARIO)

Candidemia | Candidiasis, Invasive

United States, Korea, Republic of, Greece, Canada, France, Belgium, Germany, Italy, Spain, South Africa, Bulgaria, Israel
Astellas Pharma Inc

Completed

Study of Micafungin in Patients With Invasive Candidiasis or Candidemia

Candidemia | Candidiasis

Belgium, France, Germany, Spain, United States, India, Canada, Brazil, Switzerland, Austria, Croatia, Netherlands, Poland, Czech Republic, United Kingdom
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Early-Onset Sepsis Surveillance Study (EOS)

Sepsis | Gram-Negative Bacterial Infections | Gram-Positive Bacterial Infections | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants (Vitamin A)

Sepsis | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Respiration, Artificial | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure (Preemie iNO)

Pneumonia | Sepsis | Hypertension, Pulmonary | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn | Respiratory Distress Syndrome (RDS)

United States

Clinical Trials on Sepsis, Endotoxemia, Immunosuppression in Ireland

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