Clinical Trials on Severe Mental Disorder

Total 185535 results

Institut National de la Santé Et de la Recherche...
Assistance Publique - Hôpitaux de Paris; Institut Pasteur

Completed

Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage (FluBAL)

Influenza | Acute Respiratory Distress Syndrome | Acute Lung Injury

France
Southeast University, China
Nanjing Medical University

Unknown

Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome | Adrenal Insufficiency
University of Virginia

Unknown

Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients

Pneumonia | Respiratory Syncytial Virus Infections | Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States
University of Alberta
Capital Health, Canada

Completed

Capturing Outcomes of Clinical Activities Performed by a Rounding Pharmacist Practising in a Team Environment

Pneumonia | Diabetes Mellitus, Type 2 | Pulmonary Disease, Chronic Obstructive | Coronary Arteriosclerosis | Heart Failure, Congestive

Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant (GVHD)

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal... and other conditions

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Terminated

Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection

HIV Infection | Unspecified Adult Solid Tumor, Protocol Specific | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Recurrent Breast Cancer | Recurrent Ovarian Epithelial Cancer | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult... and other conditions

United States
Assiut University

Recruiting

Predictors and Prognostic Factors of Myasthenia Gravis Outcome

Nervous System Diseases | Autoimmune Diseases of the Nervous System | Thymoma | Myasthenia Gravis | Neuromuscular Junction Diseases | Myasthenia Gravis, Generalized | Myasthenia Gravis Crisis | Myasthenia Gravis, Ocular | Myasthenia Gravis, Juvenile Form | Thymus Hyperplasia | Myasthenia Gravis With Exacerbation... and other conditions

Egypt
Children's Oncology Group

Recruiting

A Study of SNDX-5613 in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | Recurrent Mixed Phenotype Acute Leukemia | Refractory Mixed Phenotype Acute Leukemia | Refractory Acute Leukemia of Ambiguous Lineage | Recurrent Acute Leukemia of Ambiguous Lineage | Recurrent Acute Myeloid Leukemia... and other conditions

United States
Northwestern University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Seagen Inc.

Withdrawn

Brentuximab Vedotin and Pembrolizumab in Treating Patients With Recurrent Peripheral T-Cell Lymphoma

Recurrent Angioimmunoblastic T-Cell Lymphoma | Refractory Angioimmunoblastic T-Cell Lymphoma | Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified | Recurrent Enteropathy-Associated T-Cell Lymphoma | Recurrent Follicular T-Cell Lymphoma | Recurrent Hepatosplenic T-Cell Lymphoma | Recurrent... and other conditions

United States
BeiGene

Completed

Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell Neoplasms

Cutaneous T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Adult Nasal Type Extranodal NK/T-cell Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Positive | Extranodal NK/T-cell Lymphoma, Nasal Type | Peripheral T Cell Lymphoma | Extranodal NK/T-cell Lymphoma | Peripheral... and other conditions

China, Taiwan, Germany, France, Canada, Italy
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Relapsed or Refractory Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Splenic Marginal Zone Lymphoma | Anaplastic Large Cell Lymphoma | Recurrent Adult Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent... and other conditions

United States
Washington University School of Medicine
Wugen, Inc.

Recruiting

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

Acute Myeloid Leukemia | Sezary Syndrome | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Adult T Cell Leukemia | Adult T Cell Lymphoma | Hepatosplenic T-cell Lymphoma | Peripheral T Cell Lymphoma | Extranodal NK/T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | T-Cell Non-Hodgkin... and other conditions

United States
Sumithira Vasu

Completed

Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Evaluating Dactinomycin and Vincristine in Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Ewing Sarcoma of Bone | Ewing Sarcoma | Childhood Acute Lymphoblastic Leukemia | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Rhabdomyosarcoma | Childhood Soft Tissue Sarcoma | Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor...

United States, Australia, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Childhood Burkitt Lymphoma | Untreated Childhood Acute Lymphoblastic Leukemia | Stage I Childhood Large Cell Lymphoma | Stage I Childhood Small Noncleaved Cell Lymphoma | Stage II Childhood Large Cell Lymphoma | Stage II Childhood Small Noncleaved Cell Lymphoma and other conditions

United States
Amir Mortazavi
National Cancer Institute (NCI); Arno Therapeutics

Completed

AR-42 in Treating Patients With Advanced or Relapsed Multiple Myeloma, Chronic Lymphocytic Leukemia, or Lymphoma

Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Undifferentiated Carcinoma | Fallopian Tube Carcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube... and other conditions

United States
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Individual Nutrition Support in HBV-ACLF Patients at Nutrition Risk

Acute-On-Chronic Liver Failure | Malnutrition | Nutrition Support | Hepatitis B,Chronic

China
Dasman Diabetes Institute

Recruiting

Kuwait Adult Diabetes Epidemiological Multidisciplinary (KADEM) Program (KADEM)

PreDiabetes | NAFLD - Nonalcoholic Fatty Liver Disease | Diabetes Mellitus Type 2, Diabetes Mellitus Type 1

Kuwait
Universitair Ziekenhuis Brussel

Recruiting

Non-invasive Ventilation in Preterm Infants

Premature Birth | Respiratory Distress Syndrome | Ventilator Lung; Newborn

Belgium
Wuhan Union Hospital, China

Not yet recruiting

Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV

Acute Respiratory Distress Syndrome | Right Ventricular Dysfunction | Transesophageal Echocardiography

China
University of Pennsylvania

Recruiting

Feasibility of Semaglutide in Advanced Lung Disease

Obesity | Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension | Interstitial Lung Disease | Sarcoidosis, Pulmonary

United States
Shanghai Zhongshan Hospital

Recruiting

Determine the Effects of Prone Positioning and NO in COVID-19 ARDS by EIT

COVID-19 | Respiratory Distress Syndrome, Adult

China
National Cancer Institute (NCI)

Recruiting

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Myeloproliferative Neoplasm

United States, Canada
Institut National de la Santé Et de la Recherche...

Recruiting

Modifying Factors in Striated Muscle Laminopathies (LMNAModifier)

Laminopathies | Emery Dreifuss Muscular Dystrophy 2 | LMNA-Related Congenital Muscular Dystrophy | Dilated Cardiomyopathy-1A

France
Hospital Moinhos de Vento

Not yet recruiting

Long-term Impact of COVID-19 Among COVID-19 Patients With Acute Respiratory Distress Syndrome in Brazil

COVID-19 | ARDS
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial (CIRCA-19 RCT)

Covid19 | Acute Respiratory Distress Syndrome

Canada
MEDSI Clinical Hospital 1, ICU

Recruiting

Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Respiratory Tract Infections | Pneumonia | Sepsis | Critical Illness | Respiratory Distress Syndrome | Pneumonia, Ventilator-Associated | Bloodstream Infection

Russian Federation
Boston Children's Hospital
CureAP4 Foundation

Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

Hereditary Spastic Paraplegia | SPG50 | SPG47 | SPG51 | SPG52 | AP4-related Hereditary Spastic Paraplegia | Early Onset Hereditary Spastic Paraplegia | SPG4 | SPG3A | SPG15 | SPG11

United States
The University of Queensland

Recruiting

The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis

Pulmonary Fibrosis | Dyskeratosis Congenita | Telomere Shortening | Telomere Disease

Australia
Dr Christophe LENCLUD

Recruiting

Curosurf® in Adult Acute Respiratory Distress Syndrome Due to COVID-19 (Caards-1)

COVID-19 | ARDS, Human

France
Hospices Civils de Lyon

Recruiting

Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia (VT4COVID)

Pneumonia | Acute Respiratory Distress Syndrome | COVID19 | Sars-CoV2

France
Jacqueline Garcia, MD
National Institutes of Health (NIH)

Recruiting

Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

Acute Myeloid Leukemia (AML) | Chronic Myelomonocytic Leukemia (CMML) | Myelodysplastic Syndrome (MDS) | Hematopoietic Stem Cell Transplant | MDS/Myeloproliferative Neoplasm-unclassifiable (MDS/MPN-unclassifiable)

United States
National Cancer Institute (NCI)

Completed

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)

Parents of Children With Cancer | Parents of Children With NF1 | Parents of Children With Neurofibromatosis Type I

United States, Canada
Prashant Nasa

Completed

Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation

Respiratory Failure | Respiratory Distress Syndrome | Right Ventricular Dysfunction | Extracorporeal Membrane Oxygenation Complication | Extracorporeal Circulation; Complications | Right Heart Failure

United Arab Emirates
Nanyang Technological University
Tan Tock Seng Hospital; Ministry of Health, Singapore

Completed

Diabetes Footcare Companion App for Patients and Carers

Diabetes Mellitus, Type 2 | Diabetic Foot | Diabetic Foot Infection | Ulcer Foot | Diabetes Mellitus Foot Ulcer | Ulcer, Leg

Singapore
Nantes University Hospital
National Research Agency, France

Completed

Pathological Findings of Fatal COVID-19 (HISTOCOVID)

Covid19 | Respiratory Distress Syndrome | SARS-CoV-2 | Intensive Care Units | Pathology

France
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency
Eli Lilly and Company
Loxo Oncology, Inc.

Active, not recruiting

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Acute Myeloid Leukemia (AML) | Chronic Myelomonocytic Leukemia (CMML) | Myelodysplastic Syndrome (MDS) | Myeloproliferative Neoplasms (MPNs)

United States, Spain, Korea, Republic of, France, Taiwan, Australia, Belgium, Singapore, Israel, Canada, Germany, Finland
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Active, not recruiting

MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus (MERMAID-T1D)

Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Diabetes Mellitus Complication | Metabolic Disease | Type1 Diabetes Mellitus | Autoimmune Diabetes | Juvenile Diabetes

United States
Inmunova S.A.
Linical Co., Ltd.; KLIXAR; PHV LATAM

Completed

A Study to Assess Safety, Efficacy, and Pharmacokinetics of INM004 in Pediatric Patients With STEC-HUS

Hemolytic-Uremic Syndrome | Pediatric Kidney Disease | Diarrhea-Associated Hemolytic Uremic Syndrome

Argentina
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Completed

Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Myeloblasts 10 Percent or More of Bone Marrow Nucleated Cells

United States
Guangdong Provincial People's Hospital

Withdrawn

Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary Tumor (CoVac-Lung)

Vaccine Adverse Reaction | Lung Cancer | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

China
Gazi University

Completed

Effectiveness of Buerger Allen Exercise Among Type 2 Diabetes Mellitus Patients With Foot Ulcer

Diabetic Foot Ulcers

Turkey
APR Applied Pharma Research s.a.

Withdrawn

Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 (AVICOVID-3)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI
University Hospital, Ghent

Completed

Clinical Study to Determine the Optimal Operation Parameters During CO2 Removal With the Abylcap® System

ARDS (Acute Respiratory Distress Syndrome) | Respiratory Acidosis

Belgium
University Hospital, Ghent

Completed

Veno-venous Extracorporeal CO2 Removal in ARDS-patients to Treat Respiratory Acidosis

ACUTE RESPIRATORY DISTRESS SYNDROME

Belgium
Goethe University

Completed

Prospective Electroencephalography Evaluation of Sedation in COVID-19

Pathologic Processes | Acute Respiratory Distress Syndrome | Corona Virus Infection | Electroencephalogram | Conscious Sedation

Germany
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Cwm Taf University Health Board (NHS)
Cardiff University; Imperial College London; University of Oxford

Completed

Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes

Diabetes Mellitus, Type 1 | SARS-CoV2 Infection

United Kingdom

Clinical Trials on Severe Mental Disorder

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