Clinical Trials on Silver Diamine Fluoride in United States

Total 4400 results

University of Colorado, Denver
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Preventing Caries in Preschoolers: Testing a Unique Service Delivery Model in American Indian Head Start Programs

Fluoride Varnish and Oral Health Promotion | Usual Care

United States
NYU Langone Health

Completed

Band Holiday Study

Famine

United States
Vanderbilt University

Approved for marketing

Long Term Treatment With L-DOPS

Dopamine Beta Hydroxylase (DBH) Deficiency

United States
University of California, Berkeley
University of California, San Francisco; Lawrence Berkeley National Laboratory

Completed

Dopaminergic Mechanisms Underlying Human Social Behavior

Executive Function | Decision Making | Dopamine

United States
University of Pennsylvania

Active, not recruiting

Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT

Healthy Volunteer | D3 Dopamine Receptor | Cocaine-dependent

United States
WestEd
Department of Health and Human Services; Urban Strategies

Recruiting

Opportunities Beyond the Narrative: An Intervention for Justice-Involved Youth

Study Will Examine the Impact of Project With

United States
University of Oxford

Completed

Pramipexole and Emotional Processing (PEP)

Emotions | Motivation | Dopamine | Reward

United Kingdom
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Terminated

Dopamine D2/D3 Receptor Upregulation by Varenicline in Methamphetamine Users

Cognitive Function | Methamphetamine Abuse | Dopamine D2/3 Receptor Availability

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan Anemia

Steroid-refractory Diamond-Blackfan Anemia (DBA)

United States
VA Office of Research and Development
VA Sierra Nevada Health Care System

Recruiting

Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans

Thiamine Deficiency | Thiamine Deficiency; Sequelae

United States
Metabolic Technologies Inc.

Completed

Alternate Dosing Strategies for Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation: Effect on Plasma HMB Responses

Focus of the Study is to Examine Plasma HMB Levels After Oral HMB Supplementation

United States
St. Jude Children's Research Hospital

Completed

Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias

Anemia, Aplastic | Diamond-Blackfan Anemia | Amegakaryocytic Thrombocytopenia | Kostmann Syndrome

United States
University of South Carolina
Rutgers, The State University of New Jersey; Compound Solutions Inc.

Completed

The Effects of a Combination of TeaCrine®, Dynamine, and Caffeine in Law Enforcement

Caffeine, Teacrine, and Dynamine: Effects on Performance

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Treatment of Orthostatic Hypotension

Autonomic Nervous System Diseases | Orthostatic Hypotension | Orthostatic Intolerance | Dopamine Beta-Hydroxylase Deficiency

United States
Vanderbilt University Medical Center

Completed

The Pathophysiology of Orthostatic Hypotension

Autonomic Nervous System Diseases | Orthostatic Hypotension | Orthostatic Intolerance | Dopamine Beta-Hydroxylase Deficiency

United States
Masonic Cancer Center, University of Minnesota
National Marrow Donor Program

Completed

Stem Cell Transplant for Hemoglobinopathy

Sickle Cell Disease | Thalassemia | Severe Congenital Neutropenia | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome

United States
Masonic Cancer Center, University of Minnesota

Completed

Stem Cell Transplant for Bone Marrow Failure Syndromes

Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome | Kostmann's Neutropenia

United States
University of New England

Recruiting

Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults

Caries Arrested | Caries; Dentin | Caries Roots | Flouride Varnish

United States
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
Stanford University
University of Alabama at Birmingham; University of Minnesota

Completed

Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Pilot Study (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United Kingdom, United States, Germany
Washington State University

Completed

Acute Effects of Cannabigerol

Focus: To Examine Acute Effects of CBG on Anxiety, Stress, and Cognition

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia

Diamond Blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Anemia, Diamond-Blackfan

United States
Northwell Health

Terminated

Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia (ACE-011-DBA)

Diamond Blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure

Aplastic Anemia | Pure Red Cell Aplasia | Diamond Blackfan Anemia

United States
University of California, San Francisco
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Tufts... and other collaborators

Completed

The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine

Vitamin B1 Deficiency | Thiamine Deficiency

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders

Myelodysplastic Syndromes | Leukemia | Congenital Amegakaryocytic Thrombocytopenia | Severe Congenital Neutropenia | Diamond-blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia

Anemia, Aplastic | Red-Cell Aplasia, Pure | Anemia, Diamond-Blackfan

United States
Feinstein Institute for Medical Research
Diamond Blackfan Anemia Foundation, Inc.

Recruiting

Diamond Blackfan Anemia Registry (DBAR) (DBAR)

Anemia | Blood Disease

United States
Mayo Clinic
ARUP Laboratories; Eastern Mennonite Missions

Completed

Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants

Beriberi

United States, Cambodia
Case Western Reserve University

Completed

Measuring Brain Activity of School Age Children

Neurobehavioral Manifestations | Dopamine | Perinatal Hypoxia

United States
Emory University
Children's Healthcare of Atlanta

Terminated

Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation

Sickle Cell Disease | Fanconi Anemia | Thalassemia | Severe Congenital Neutropenia | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Leukocyte Adhesion Deficiency | Dyskeratosis-congenita | Chediak-Higashi Syndrome | Chronic-granulomatous Disease | Schwachman-Diamond...

United States
Adrianna Vlachos, MD

Terminated

The Use of Trifluoperazine in Transfusion Dependent DBA (DBA)

Pure Red Cell Aplasia | Diamond Blackfan Anemia

United States
Talaris Therapeutics Inc.
Duke University

Withdrawn

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Anemia, Sickle Cell | Thalassemia | Beta-Thalassemia | Bone Marrow Failure Syndromes | Diamond-Blackfan Anemia | Alpha-Thalassemia | Complex and Transfusion-dependent Hemoglobinopathies

United States
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Survey Study (MCSIO) (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States, United Kingdom, Germany
Northwell Health

Completed

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia (LeucineDBA)

Pure Red Cell Aplasia | Diamond Blackfan Anemia | Blackfan Diamond Syndrome | DBA | Congenital Hypoplastic Anemia

United States
Beth Israel Deaconess Medical Center

Completed

Thiamine as a Renal Protective Agent in Septic Shock

Sepsis | Kidney Injury | Thiamine Deficiency

United States
Jason Robert Gotlib
Celgene Corporation

Terminated

Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia

Leukemia | Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission

Leukemia | Thrombocytopenia | Fanconi Anemia | Congenital Amegakaryocytic Thrombocytopenia | Severe Congenital Neutropenia | Diamond-blackfan Anemia

United States
National Cancer Institute (NCI)

Recruiting

Cancer in Inherited Bone Marrow Failure Syndromes

Fanconi Anemia | Dyskeratosis Congenita | Diamond Blackfan Anemia | Shwachman Diamond Syndrome | Inherited Bone Marrow Failure Syndrome, Aplastic Anemia

United States
Boston Children's Hospital
Children's Hospital Medical Center, Cincinnati

Recruiting

Shwachman Diamond Syndrome Registry and Study (SDSR)

Shwachman-Diamond Syndrome | Shwachman-Diamond Syndrome-Like

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Medical Treatment for Diamond Blackfan Anemia

Hematologic Disease | Fanconi's Anemia

United States
Diane George

Active, not recruiting

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Sickle Cell Disease | Hemoglobinopathies | Severe Congenital Neutropenia | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Macrophage Activation Syndrome | Bone Marrow Failure Syndrome | Amegakaryocytic Thrombocytopenia | Schwachman Diamond Syndrome | Primary Immunodeficiency Syndromes | Acquired Immunodeficiency... and other conditions

United States
Howard University
Medical Home Development Group; Geneus Health

Unknown

SMART Brain Health in African-Americans (SMART)

Opioid Use Disorder | Substance Use Disorders | Dopamine Dysregulation Syndrome | African Americans

United States
Masonic Cancer Center, University of Minnesota
National Cancer Institute (NCI)

Terminated

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Diamond-blackfan Anemia

United States
St. Jude Children's Research Hospital
Baylor College of Medicine; Children's Hospital of Philadelphia; Dana-Farber... and other collaborators

Recruiting

Investigation of the Genetics of Hematologic Diseases

Myelodysplastic Syndromes | Sickle Cell Disease | Fanconi Anemia | Severe Congenital Neutropenia | Bone Marrow Failure Syndromes | Blood Coagulation Disorder | Erythrocyte Disorder | Leukocyte Disorder | Hemostasis | Dyskeratosis Congenita | Diamond-Blackfan Anemia | Congenital Thrombocytopenia | Myeloproliferative...

United States
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
Rising Tide Foundation

Completed

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

Delirium | Hematopoietic Stem Cell Transplantation | Thiamine Deficiency

United States
The Cleveland Clinic

Withdrawn

Thiamine Supplementation in Patients With Septic Shock

Septic Shock | Shock, Septic | Lactic Acidosis | Thiamine Deficiency

United States

Clinical Trials on Silver Diamine Fluoride in United States

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