Clinical Trials on Spasticity in United Kingdom

Total 195 results

Ipsen

Completed

A Single Centre, Prospective, Observational Study to Assess the Use of the Rehabilitation Tool, GripAble, in Patients With Upper Limb Spasticity Receiving Botulinum Toxin-A (BoNT-A) in the United Kingdom (UK).

Upper Limb Spasticity (ULS)

United Kingdom
Ipsen

Completed

A Study to Review Treatment Outcomes From Treatment With Dysport® Injections in Adults for Upper and/or Lower Limb Focal Spasticity (DYSCOVER)

Upper and/or Lower Limb Focal Spasticity

United Kingdom
Ipsen

Completed

A Study to Assess Treatment Outcomes of abobotulinumtoxinA and onabotulinumtoxinA Treatments in Real Life Practice in Toxin-naïve Adult Patients With Limb Spasticity.

Spasticity Related to Any Cause Except Cerebral Palsy

United Kingdom
Ipsen

Completed

Validation of the Spasticity Related Quality of Life Questionnaire (SQOL-6D)

Spasticity, Muscle

United Kingdom
Canbex Therapeutics Ltd

Completed

Study of VSN16R for the Treatment of Spasticity in Multiple Sclerosis

Spasticity in People With Multiple Sclerosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Multi-channel Stimulation for Post Stroke Spasticity (MUSTS) (MUSTS)

Stroke | Muscle Spasticity

United Kingdom
Robert Jones and Agnes Hunt Orthopaedic and District...

Recruiting

Pulsed Magnetic Stimulation - Managing Spasticity in Spinal Cord Injury (OsStim)

Spinal Cord Injuries

United Kingdom
Jazz Pharmaceuticals

Completed

A Study of the Safety and Effectiveness of Sativex®, for the Relief of Symptoms of Spasticity in Subjects, From Phase B, With Multiple Sclerosis (MS)

Multiple Sclerosis | Spasticity

United Kingdom
Sandwell & West Birmingham Hospitals NHS Trust
Stroke Research Network; Keele University

Completed

Early Use of Botulinum Toxin in Spasticity Post Stroke. (EUBoSS)

Stroke | Muscle Spasticity | Contracture

United Kingdom
Merz Pharmaceuticals GmbH

Completed

IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity (NT-Spin)

Upper Limb Spasticity

France, Spain, Switzerland, United Kingdom, Italy, Austria, Germany, Portugal
Jazz Pharmaceuticals

Completed

Evaluate the Maintenance of Effect After Long-term Treatment With Sativex® in Subjects With Symptoms of Spasticity Due to Multiple Sclerosis

Multiple Sclerosis | Spasticity

United Kingdom
Jazz Pharmaceuticals

Completed

A Study of Sativex® for Relief of Spasticity in Subjects With Multiple Sclerosis.

Multiple Sclerosis | Spasticity

United Kingdom
MedtronicNeuro

Completed

SISTERS: Spasticity In Stroke Study - Randomized Study (SISTERS)

Severe Spasticity

Belgium, Spain, United States, Austria, Germany, Italy, Netherlands, Slovenia, United Kingdom
Medtronic

Completed

Medtronic PSR TDD PMCF

Chronic Pain | Spasticity, Muscle

Belgium, Spain, Czechia, France, Netherlands, Slovenia, Switzerland, United Kingdom
Pacira Pharmaceuticals, Inc

Completed

Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III Device

Upper Limb Spasticity

United States
Pacira Pharmaceuticals, Inc

Recruiting

Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity

Spasticity, Cerebral or Spinal Condition

United States
Shirley Ryan AbilityLab

Suspended

Robotic Interventions for Spasticity Treatment

Stroke | Spasticity, Muscle

United States
JoAnn Harnar
Allergan

Completed

Efficacy and Safety Study of Botulinum Neurotoxin A With Rehabilitation Versus Botulinum Neurotoxin A Alone in Treatment of Post-stroke Spasticity

Upper Limb Spasticity

United States
Jazz Pharmaceuticals

Completed

A Long-term Safety Extension Study of Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) in Multiple Sclerosis

Multiple Sclerosis | Spasticity

United Kingdom
Ospedale Generale Di Zona Moriggia-Pelascini

Suspended

Reliability of Spasticity Measurement With Lokomat

Spasticity, Lokomat

Italy
Jazz Pharmaceuticals

Completed

A Safety, Efficacy and Tolerability Study of Sativex for the Treatment of Spasticity in Children Aged 8 to 18 Years

Cerebral Palsy

Czechia, Israel, United Kingdom
Vanderbilt University Medical Center
Allergan

Completed

Using Telemedicine to Improve Spasticity Diagnosis Rates

Nervous System Diseases | Neurologic Manifestations | Muscular Diseases | Neuromuscular Manifestations | Muscle Hypertonia | Spasticity, Muscle | Muscle Spasticity | Musculoskeletal Disease | Signs and Symptoms

United States
Vanderbilt University Medical Center
Ipsen

Completed

Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity

Nervous System Diseases | Neurologic Manifestations | Muscular Diseases | Neuromuscular Manifestations | Muscle Hypertonia | Spasticity, Muscle | Muscle Spasticity | Musculoskeletal Disease | Signs and Symptoms

United States
Piramal Critical Care, Ltd.

Completed

Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump

Severe Spasticity

United States
Allergan

Completed

BOTOX® Economic Spasticity Trial (BEST)

Muscle Spasticity

Canada, Sweden, Germany, United Kingdom
William Carey University
American Osteopathic Association

Active, not recruiting

Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI

Quality of Life | Pain | Spasticity, Muscle

United States
AbbVie

Active, not recruiting

Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity

Upper Limb Spasticity

United States
Ipsen

Completed

Effectiveness and Safety of Dysport® (abobotulinumtoxinA) in Paediatric Lower Limb Spasticity

Lower Limb Spasticity

United States
Jazz Pharmaceuticals

Completed

A Study of the Long-term Safety of Sativex Use

Pain | Multiple Sclerosis | Spasticity

United Kingdom
Ipsen

Recruiting

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development (EPITOME)

Spasticity as Sequela of Stroke

United States, Spain, Germany, France, United Kingdom, Italy, Sweden
Jazz Pharmaceuticals

Terminated

Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis (RELEASE MSS5)

Spasticity With Multiple Sclerosis

Spain, United States, United Kingdom, Czechia, Poland
Ipsen

Completed

Attainment of Person-centred Goals After Botulinum Toxin Treatment for Upper Limb Spasticity in Real Life Practice (ULIS III)

Upper Limb Spasticity

Taiwan, United States, Germany, Australia, Hong Kong, Philippines, France, Russian Federation, Italy, Portugal, Brazil, Austria, Mexico, Poland
University of Texas Southwestern Medical Center

Completed

Effects of Soft Tissue Lengthening on Gait in Children With Spasticity

Muscle Spasticity

United States
Vanderbilt University

Completed

Optical Stimulation in Peripheral Nerves for Select Rhizotomy Procedures (Rhizotomy)

Spasticity

United States
Ipsen

Recruiting

A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity. (DIRECTION)

Upper Limb Spasticity

United States, France, Canada, Puerto Rico
Vanderbilt University
Allergan; Merz North America, Inc.

Completed

Prevalence of Spasticity in Veterans Living in a Long-term Care Facility

Spasticity

United States
Ipsen

Completed

Study to Assess the Effectiveness of AboBoNT-A Injections for Adult Lower Limb Spasticity in a Real Life Cohort (AboLiSh)

Adult Lower Limb Spasticity

United States, Australia, Brazil, Canada, France, Germany, Italy, Poland, Russian Federation
Acorda Therapeutics

Completed

A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial (TQT)

Spasticity

United States
Vanderbilt University

Terminated

Botox vs. Baclofen for Upper Limb Spasticity

Spasticity

United States
Shirley Ryan AbilityLab
Allergan

Completed

Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity

Post-stroke Shoulder Pain and Spasticity

United States
Vanderbilt University
Merz North America, Inc.

Completed

Reliability of an Algorithm to Diagnose Spasticity

Spasticity

United States
Allergan

Completed

An Adult Spasticity Registry of OnabotulinumtoxinA Treatment (ASPIRE)

Muscle Spasticity

Spain, Italy, United States, Germany, United Kingdom, Taiwan, France
Saol Therapeutics Inc

Active, not recruiting

Phase II Study to Assess Safety, Pharmacokinetics and Efficacy of SL-1002 for Limb Spasticity (RAISE)

Spasticity

United States
Hospital for Special Surgery, New York

Terminated

rTMS in Treatment of Spasticity

ALS

United States
Johns Hopkins University
Saluda Medical Pty Ltd

Not yet recruiting

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity (CLONUS)

Chronic Pain | Spasticity as Sequela of Stroke | Upper Motor Neuron Lesion

United States
Ohio State University
Varian Medical Systems; Centro Diagnostico Milano, Co-PI: Pantaleo Romanelli...

Recruiting

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy (SPASM)

Spasticity, Muscle | Spastic Cerebral Palsy | Spasticity as Sequela of Stroke

United States, Italy
Acorda Therapeutics
Syneos Health

Terminated

Phase 1b Study of Tizanidine in Pediatric Patients With Cerebral Palsy

Spasticity Due to Cerebral Palsy

United States
Medical University of South Carolina
National Institute of General Medical Sciences (NIGMS)

Completed

DDN in Stroke--COBRE (CDN)

Stroke | Spasticity, Muscle | CVA

United States
Ipsen

Completed

Efficacy And Safety Of Dysport In The Treatment Of Upper Limb Spasticity In Children (PUL)

Upper Limb Spasticity (Altered Skeletal Muscle Performance) in Children

United States, Poland, Spain, Belgium, Israel, Turkey, Czechia, Mexico
Revance Therapeutics, Inc.

Completed

Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity (JUNIPER)

Upper Limb Spasticity

United States

Clinical Trials on Spasticity in United Kingdom

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