Clinical Trials on Spinal Diseases in South Africa

Total 18798 results

Aeras
Statens Serum Institut

Completed

A Phase I/IIa AERAS-456 in HIV-Negative Adults With & Without Latent Tuberculosis Infection (C-035-456)

Latent Tuberculosis | Latent Tuberculosis Bacteriology and Histology Unknown

South Africa
Johns Hopkins University
Aurum Institute; UNITAID; KNCV Tuberculosis Foundation

Completed

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Tuberculosis Infection | Tuberculosis Prevention

Ethiopia, South Africa
Pelvic Floor Research Foundation of South Africa
University of Cape Town

Unknown

To Evaluate the Use of Bioresorbable Tephaflex™ Sling for Stress Urinary Incontinence (Tephaflex)

Stress Urinary Incontinence

South Africa
Population Council
United States Agency for International Development (USAID); Bill and Melinda...

Completed

Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission

HIV Infections | Sexually Transmitted Diseases | AIDS | HIV Seroconversion

South Africa
University of Cape Town

Completed

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry (PERFUSION)

Acute Coronary Syndrome | Unstable Angina | ST Elevated Myocardial Infarction | Non ST Elevation Myocardial Infarction

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
Nuvaira, Inc.

Completed

Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation (IPS-I)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, South Africa
Massachusetts General Hospital
National Institute of Mental Health (NIMH); Match Research

Completed

Support for Perinatal Adherence and Depression (INSPireD)

Depression | Human Immunodeficiency Virus

United States, South Africa
ApoPharma

Completed

Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects

Asymptomatic HIV Infection

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
Thrombosis Research Institute
Sanofi

Terminated

Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients (ETHIC)

COVID-19

Australia, Belgium, South Africa
Eli Lilly and Company

Completed

A Study of LY2623091 in Male and Females With Chronic Kidney Disease

Chronic Kidney Disease

Bulgaria, South Africa
Medtronic BRC

Unknown

RESpiration deTection From Implanted Cardiac Devices in Subjects With Heart Failure (REST-HF) (REST-HF)

Heart Failure

Belgium, South Africa
Hoffmann-La Roche

Completed

An Observational Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) in Stage V Chronic Kidney Disease Participants on Hemodialysis

Anemia

South Africa
FHI 360
University of Cape Town; City University of New York, School of Public Health

Completed

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women

HIV

South Africa
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - Dir. Gen. for Cooperation and Development

Completed

Study to Assess the Seroprevalence of Anti-Tat Antibodies in HIV-infected Patients (ISS OBS T-004)

HIV Infection

South Africa
Boehringer Ingelheim

Completed

Trial to Evaluate Steady State Pharmacokinetic Parameters, Efficacy and Safety of Nevirapine in Antiretroviral Drug naïve Pediatric Patients

HIV Infections

South Africa
University of Stellenbosch

Completed

Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature Infants

Necrotizing Enterocolitis

South Africa
University of Washington
Harvard Medical School (HMS and HSDM); National Institute of Mental Health... and other collaborators

Completed

The Prevention Options for Women Evaluation Research (POWER) Cohort

HIV/AIDS

Kenya, South Africa
University of Stellenbosch
Thrasher Research Fund

Unknown

The Effect of Bacille Calmette Guerin (BCG) Vaccination on Immune Responses in HIV-Exposed and Unexposed Infants

HIV Infections

South Africa
Advanced Imaging Projects, LLC
All India Institute of Medical Sciences, New Delhi; US Department of Veterans... and other collaborators

Not yet recruiting

Safety and Efficacy of Ga68 Αvβ3 IAC PET/CT for Diagnosis and Clinical Management in Angiogenic Breast Cancer Patients (Shiva)

Angiogenic Breast Cancer

South Africa, India
Maastricht Radiation Oncology

Completed

Predicting Outcome in Cervix Carcinoma: a Prospective Study (POCER)

Cervical Cancer

Netherlands, South Africa
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Cryptococcal Optimal ART Timing Trial (COAT)

HIV Infections | AIDS | Cryptococcal Meningitis

Uganda, South Africa
Novartis Pharmaceuticals

Completed

A Phase l Study to Evaluate the Pharmacokinetics and Safety Pasireotide in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Volunteers

Renal Impairment

Germany, South Africa
University of Cape Town
Medical University of Vienna; University of Washington

Completed

Acid-Base and Point of Care Ultrasound in Severe Preeclampsia

Pre-Eclampsia

South Africa
Otsuka Frankfurt Research Institute GmbH

Completed

Safety, Efficacy and Pharmacokinetics of OPC-67683 in Patients With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa (DISCO)

HIV-1-infection

Uganda, South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; University of Stellenbosch

Withdrawn

Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women

HIV Infection | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | FIGO Stage IIB Cervix Carcinoma | FIGO Stage III Cervix Carcinoma | FIGO Stage IVA Cervix Carcinoma

South Africa, Zimbabwe
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Preparedness Study - HPV Vaccine

Sexual Transmission of Infection

United States, South Africa
Medtronic BRC

Terminated

Model 20105 Lead Study

Sick Sinus Node Syndrome

South Africa, Netherlands, Canada, Singapore
Cytheris SA

Terminated

Randomized Study on Multiple Cycles of Interleukin-7 in HIV Patients Immune Non-responders (Inspire 3)

HIV

Switzerland, Italy, South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)

Tuberculosis

Haiti, South Africa
Pfizer

Completed

A Multicenter Extension Study of Taliglucerase Alfa in Pediatric Subjects With Gaucher Disease

Gaucher Disease

Israel, Paraguay, South Africa
MedImmune LLC
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Trial to Compare the Safety, Tolerability, and Efficacy of Influenza Virus Vaccine, (CAIV-T) With Inactivated, Influenza Vaccine, Trivalent, Types A & B, in Adults Aged 60 Years and Older Against Culture-confirmed Influenza (FluMist)

Influenza

South Africa
BioNTech SE

Recruiting

Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated Volunteers

Tuberculosis

South Africa
Serum Institute of India Pvt. Ltd.
Bill and Melinda Gates Foundation

Not yet recruiting

Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 Years

Human Papillomavirus Infection

Kenya, Mozambique, South Africa
University of Pretoria
University of Stellenbosch

Active, not recruiting

Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts (TheraVACCS)

Genital Warts

South Africa
University of Miami
United States Department of Defense

Recruiting

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

Spinal Cord Injury, Acute

United States
University of Stellenbosch
University of Pittsburgh

Unknown

TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial

Tuberculosis

South Africa
MedImmune LLC

Completed

A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom, South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) (DOLPHIN KIDS)

HIV | Tuberculosis

South Africa
Virginia Commonwealth University
United States Department of Defense; McGuire Veterans Hospital; Immersive Experience...

Recruiting

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury (VRWalk)

Neuropathic Pain | Spinal Cord Injuries

United States, Australia
Zimmer Biomet

Terminated

A Multicentre Trial to Compare Two Articulating Bearing Surfaces as Used in Cementless Primary Hip Arthroplasty (MagnumCRCT)

Osteoarthritis

Bosnia and Herzegovina, South Africa
Ottawa Hospital Research Institute
Ontario Lung Association

Withdrawn

A RCT of Prednisone as Adjunctive Therapy for Hospitalized Patients With Pulmonary TB and HIV Co-infection

HIV Infections | Tuberculosis

Canada, South Africa
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
Foundation for Innovative New Diagnostics, Switzerland
University of Cape Town; The Leona M. and Harry B. Helmsley Charitable Trust; University of Pretoria

Recruiting

Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa (ACCEDE)

Type 1 Diabetes

South Africa
Biopure Corporation

Unknown

A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery

Coronary Artery Disease

Greece, South Africa, United Kingdom
BioCryst Pharmaceuticals

Recruiting

Dose Escalation of BCX10013 in Subjects With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

South Africa, Malaysia
Boehringer Ingelheim

Completed

A Study of Single Dose Nevirapine (NVP) Combined With Combivir® for the Prevention of Mother to Child Transmission (pMTCT) - Treatment Options Preservation Study (TOPS)

Acquired Immunodeficiency Syndrome

South Africa

Clinical Trials on Spinal Diseases in South Africa

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CROs in Congo, DR of

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