Clinical Trials on Streptococcus Mutans

Total 835 results

Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018) (PNEU-WAY)

Pneumococcal Infections

United States, France, Peru, South Africa, Thailand
CIHR Canadian HIV Trials Network
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Early Versus Delayed Pneumococcal Vaccination in HIV

Pneumococcal Infections

Canada
University of Manitoba
Winnipeg Regional Health Authority

Completed

Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration

Surgery | Adult | Blepharoplasty | Anesthetics, Local | Lidocaine | Humans | Vibration | Ophthalmologic Surgical Procedure | Age-Related Ptosis

Canada
MapKure, LLC

Recruiting

A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Colorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Australia, United States
Institut National de la Santé Et de la Recherche...

Completed

Identifocation the B Cell Subsets Responsible for Anti-pneumococcal Response (PNEUMOVACB)

Pneumococcal Diseases

France
National Cancer Institute (NCI)

Suspended

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Diffuse Glioma | Secondary Glioblastoma | Glioblastoma, IDH-Wildtype | Astrocytoma, IDH-Mutant, Grade 4

United States, Puerto Rico
Walvax Biotechnology Co., Ltd.

Enrolling by invitation

A Phase 3 Study to Evaluate the Immunogenicity and Safety of Walvax's PCV13-TT as Compared to Pfizer's PCV13

Pneumococcal Disease, Invasive

Indonesia
University of Toledo Health Science Campus
National Institutes of Health (NIH)

Completed

Immune Response to Pneumococcal Vaccination in HIV Infected Individuals

Pneumococcal Infection

United States
Pfizer

Completed

Study Evaluating Prevenar in the Prevention of Invasive Pneumococcal Disease (IPD) in the Paediatric Population in Spain.

Invasive Pneumococcal Disease

Spain
Jonsson Comprehensive Cancer Center

Not yet recruiting

Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant

Diffuse Hemispheric Glioma, H3 G34-Mutant

United States
Oslo University Hospital
Karolinska University Hospital; University Hospital of North Norway; Sahlgrenska... and other collaborators

Recruiting

PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas (PRO-GLIO)

Oligodendroglioma | Oligodendroglioma, Anaplastic | Diffuse Astrocytoma, IDH-Mutant

Norway
UNC Lineberger Comprehensive Cancer Center
GlaxoSmithKline

Completed

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

Unresectable Melanoma | Stage IV Melanoma | Stage III Melanoma | BRAF Mutant Melanoma

United States
Wuhan BravoVax Co., Ltd.
Hunan Provincial Center for Disease Control and Prevention; Liaoning Chengda...

Recruiting

Phase I Clinical Trial of a Candidate PCV13 in Healthy People

Pneumococcal Infections

China
Merck Sharp & Dohme LLC

Completed

A Study of Pneumococcal Conjugate Vaccine (V114) Compared to a Marketed Vaccine (V114-003)

Pneumococcal Infections
Pfizer

Completed

A Study To Assess The Safety And Effectiveness Of Prevenar In Chinese Children Who Have Not Previously Received A Vaccine Against Pneumococcal Bacteria (6114A1-4000-CN)

Pneumococcal Infections

China
Valneva Austria GmbH
PATH

Completed

Open-Label Study Assessing The Safety, Immunogenicity and Dose Response of IC47

Pneumococcal Infections

Germany
Pfizer

Completed

Study Evaluating Safety and Immunogenicity of 13-Valent Pneumococcal Conjugate Vaccine With Influenza Vaccine in Adults

Pneumococcal Infections
National Institute of Allergy and Infectious Diseases...

Completed

Prevalence of RHD, Pyoderma and Scabies in Children in Fiji

Streptococcus Group A

Fiji
Wyeth is now a wholly owned subsidiary of Pfizer
Pfizer

Completed

Immune Response In Children Revaccinated With Pneumococcal Conjugate Vaccine (REPLAY)

Invasive Pneumococcal Disease

Iceland
GlaxoSmithKline

Completed

Safety and Immune Response Study of an Investigational Pneumococcal Vaccine.

Prophylactic Pneumococcal Diseases

Belgium
Centers for Disease Control and Prevention
Kaiser Permanente

Completed

Racial Disparities in Pneumococcal Vaccination in Managed Care

Pneumococcal Disease Prevention

United States
University of Southern Mississippi
University of Utah

Completed

Comparison of Lethal Means Counseling and an Active Control Condition, With and Without Provision of Gun Locks

Intentional Self-Harm by Other Specified Means

United States
Centre Hospitalier Princesse Grace
Pfizer; Centre Scientifique de Monaco

Completed

An Incitative Multifaceted PROcedure for Pneumococcal Vaccination at the Emergency Department (IMPROVED)

Pneumococcal Infections

France, Monaco
Pfizer

Completed

Study Evaluating the Impact of a 13-valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization

Pneumococcal Infections

Israel
Erasca, Inc.

Recruiting

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

Advanced or Metastatic NRAS-mutant Melanoma

United States
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms

Myeloproliferative Neoplasm | Myelodysplastic Neoplasm | Pathway Mutant Myelodysplastic Syndromes

United States
Beijing Chest Hospital
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

HER2 Mutant Non-small Cell Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Study of Famitinib in Combination With HS-10296 in Patients With EGFR-mutant NSCLC

EGFR-mutant Non-Small Cell Lung Cancer

China
Association Clinique Thérapeutique Infantile du...
Pfizer

Recruiting

Invasive Pneumococcal Disease Study

Mortality | Pneumococcal Infections | Pneumococcal Conjugate Vaccine | Antibiotic Treatment

France
CanSino Biologics Inc.
Henan Center for Disease Control and Prevention

Completed

Phase III Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Above (PICTPCV13i)

Pneumococcal Infections | Bacterial Infections | Streptococcal Infections

China
CanSino Biologics Inc.
Henan Center for Disease Control and Prevention

Completed

Phase I Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Above (PICTPCV13i)

Pneumococcal Infections | Bacterial Infections | Streptococcal Infections

China
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...

Completed

Surgical Planning and Informed Consent (SPLICE)

Communication | Health Knowledge, Attitudes, Practice | Informed Consent | Patient Compliance | Patient-Centered Care | User-Computer Interface | Neurosurgery | Physician-Patient Relations | Humans | Feedback, Psychological

Italy
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 When Administered Concomitantly With Influenza Vaccine in Healthy Adults 50 Years of Age or Older (V114-021/PNEU-FLU)

Pneumococcal Infections

United States
Pfizer

Completed

Study Evaluating the Impact of the 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Alaskan Native Children.

Pneumococcal Disease | 13-valent Pneumococcal Vaccine

United States
University Children's Hospital Basel

Terminated

Comparative Trial of Oral Penicillin Versus Cefuroxim for Treatment of Perianal Streptococcal Dermatitis

Streptococcal Infections

Switzerland
Pfizer

Completed

Safety and Immunogenicity of 20vPnC Coadministered With SIIV in Adults ≥65 Years of Age

Pneumococcal Disease

United States
Johns Hopkins Bloomberg School of Public Health
Pfizer; National Institutes of Health (NIH); Centers for Disease Control and...

Completed

Impact of PCV on Disease and Colonization Among Native American Communities

Invasive Pneumococcal Disease | Pneumococcal Nasopharyngeal Colonization

United States
University of Cape Town
Natal Bioproducts Institute

Completed

Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea

Sydenham Chorea | Post Streptococcal Movement Disorder

South Africa
Academisch Medisch Centrum - Universiteit van Amsterdam...
Centers for Disease Control and Prevention; Wageningen University and Research

Completed

The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses (Rota-biome)

Tetanus | Rotavirus Infections | Reaction - Vaccine Nos | Intestinal Bacteria Flora Disturbance | Streptococcal Pneumonia

Netherlands
University of California, San Francisco
National Institute of Neurological Disorders and Stroke (NINDS); The Chad-Tough... and other collaborators

Recruiting

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent WHO Grade III Glioma | WHO Grade III Glioma

United States, Netherlands, Israel, Australia, New Zealand, Switzerland
Bridge Biotherapeutics, Inc.

Recruiting

First-in-Human Study of BBT-207 in Advanced Non-Small Cell Lung Cancer Harboring EGFR Mutation After Treatment With EGFR TKI

EGFR Mutant Advanced Non-Small Cell Lung Cancer

Korea, Republic of, United States
AstraZeneca
Daiichi Sankyo

Active, not recruiting

A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC (DL-05)

HER2-mutant Non-Small Cell Lung Cancer

China
Novartis Pharmaceuticals

Active, not recruiting

Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC

EGFR-mutant Non-small Cell Lung Cancer

Taiwan, Germany, Canada, Italy, Singapore, Hong Kong
Medical University of Vienna

Not yet recruiting

Concomitant Administration of the Novavax Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years (NVX_PCV20)

COVID-19 | Pneumococcal Infections
Public Health England

Completed

A Study to Assess the Impact of Pneumococcal Conjugate Vaccination Programme on the Carriage of Pneumococci (Pneucast)

Pneumococcal Disease

United Kingdom
Novartis Vaccines

Completed

Magnitude of the Antibody Response to and Safety of a GBS Trivalent Vaccine in HIV Positive and HIV Negative Pregnant Women and Their Offsprings

Bacterial Infections | Streptococcal Infections | Gram-Positive Bacterial Infections

South Africa, Malawi
Vastra Gotaland Region
Göteborg University; James Cook University, Queensland, Australia

Completed

Antimicrobial Stewardship Program (ASP) in Patients With a Sore Throat (ASP-Throat)

Tonsillitis | Pharyngitis | Sore Throat | Streptococcus Pharyngitis | Pharyngitis Bacterial

Sweden
PATH

Completed

Nasopharyngeal Carriage Study in Healthy Kenyan Toddlers

Pneumococcal Disease

Kenya
Region Skane

Suspended

Light in Frail Elderly - the Effect of a Dynamic Light for Sleep and Circadian Rhythm (LIFE)

Inflammation | Fatigue | Sleep | Frailty | Circadian Rhythm | Aged | Cognition | Melatonin | Humans | Light | Biocentric | Karolinska Sleepiness Score

Sweden
Checkable Medical Inc
Curebase Inc.

Completed

Clinical Performance of the Checkable Medical At-Home Strep A Test

Respiratory Tract Infections | Pharyngitis | Streptococcus Pyogenes Infection

United States

Clinical Trials on Streptococcus Mutans

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