Clinical Trials on Suicidal Depression

Total 9707 results

University of Texas Southwestern Medical Center

Recruiting

Youth Depression and Suicide Research Network (YDSRN)

Depressive Disorder | Depression | Suicidal Ideation | Suicide, Attempted | Suicide | Depressive Symptoms | Depression, Anxiety | Depressive Episode | Depression and Suicide | Depression, Teen

United States
Charite University, Berlin, Germany
Janssen-Cilag G.m.b.H

Recruiting

Outcomes Associated With Suicidality in Inpatients With Symptoms of Depression (OASIS-D) (OASIS-D)

Depression | Suicidal Ideation | Suicide, Attempted | Suicidal and Self-injurious Behavior | Depression Moderate | Depression Severe

Germany
University of Alabama at Birmingham
National Institute of Mental Health (NIMH)

Recruiting

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

Depression | Suicide, Attempted | Suicide | Major Depressive Disorder | Suicidal Ideas | MDD | Depression and Suicide | Depression in Adolescence | Depression, Teen

United States
Yale University
National Institute of Mental Health (NIMH)

Recruiting

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention (ENDURE)

Depression and Suicide

United States
Tri-Service General Hospital

Recruiting

Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients: A Randomized, Sham-controlled Trial

Major Depressive Disorder | Treatment-Resistant Depression | Suicide Ideations

Taiwan
NeuroRx, Inc.
Massachusetts General Hospital; Target Health Inc.

Completed

Sequential Therapy for the Treatment of Severe Bipolar Depression. (STABIL-B)

Suicidal Ideation | Suicide, Attempted | Bipolar Depression | Suicidal Ideas

United States
Stanford University

Enrolling by invitation

Assessing the Effectiveness of Psychiatric Interventions on the Inpatient Unit

Suicidal Ideation | Depressive Symptoms

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacity of Psychological Intervention on Reducing the Suicidal Ideations, Depression Level and Improving Reinsertion (MLADO)

Depressive Symptoms

France
Novartis Pharmaceuticals

Terminated

Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

Major Depressive Disorder With Suicidal Ideation With Intent

Taiwan, Spain, Germany, Netherlands, Turkey, Mexico, United States, Malaysia, Poland, Canada, Japan, Russian Federation, Argentina, Brazil
Fundacin Biomedica Galicia Sur

Enrolling by invitation

"Youth Aware of Mental Health" in Galicia (YAM)

Suicidal Ideation | Suicide, Attempted | Depressive Symptoms | Cyberbullying | Bullying | Help-Seeking Behavior | Suicide Awareness

Spain
University of California, San Diego
Brain & Behavior Research Foundation

Recruiting

Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI (COMBAT-SI)

Suicidal Ideation | Treatment-resistant Depression

United States
New York University
National Institute of Mental Health (NIMH); Columbia University

Recruiting

Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools

Depression | Suicidal Ideation

United States
University of Alabama at Birmingham

Withdrawn

Impulsivity and Thought Process Disorder in Patients With Active Suicidal Ideation and Depression

Depression | Impulsivity | Active Suicidal Ideation

United States
NeuroRx, Inc.
Prevail Infoworks, Inc

Active, not recruiting

NRX-101 for Bipolar Depression With Subacute Suicidal Ideation

Bipolar Depression | Suicidal Ideation and Behavior

United States
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
Seelos Therapeutics, Inc.

Completed

A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide

Depressive Disorder, Major | Suicidal

United States
Eisenhower Army Medical Center
Augusta University; The Geneva Foundation; Congressionally Directed Medical Research...

Completed

TMS for Suicidal Crisis in Active Duty SMs (TMS4SI)

Suicidal Ideation | Suicide | Suicidal Intention | Suicidal Impulses | Suicidal and Self-Injurious Behavior | Suicidal Depression

United States
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH)

Recruiting

Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

Depressive Disorder | Depression | Suicidal Ideation | Major Depressive Disorder

United States
University of Pittsburgh
National Institute of Mental Health (NIMH); Pediatric Research in Office Settings

Not yet recruiting

Optimizing Suicide Prevention Strategies for Pediatric Primary Care

Depression | Suicidal Ideation | Suicidal and Self-injurious Behavior

United States
Xijing Hospital

Recruiting

Neuroimaging Guided and Robot-assisted rTMS for Suicidal Ideation of Depression

Depression | Suicidal Ideation

China
University of Pittsburgh
National Institute of Mental Health (NIMH); Kaiser Foundation Research Institute

Completed

Screening Wizard- Phase 2

Depression | Suicidal Ideation

United States
Janssen Research & Development, LLC

Completed

54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide (Aspire II)

Depressive Disorder, Major

United States, Belgium, Canada, Poland, France, Spain, Brazil, Lithuania, Czechia, Austria, Argentina, Turkey
Janssen Research & Development, LLC

Completed

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide (Aspire I)

Depressive Disorder, Major

United States, Korea, Republic of, Malaysia, Taiwan, Bulgaria, Spain, Hungary, Germany, Estonia, South Africa, Slovakia
University of Memphis

Recruiting

Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors

Suicide Ideation | Suicidal Behaviors | Depression/Anxiety

United States
Centre Hospitalier Universitaire de Besancon
Fondation FondaMental

Not yet recruiting

How to Reduce Suicidal Thoughts and Impulsivity in Depression (DEPIMPULSE)

Suicidal Ideation | Impulsive Behavior | Unipolar Depression

France
Centre Hospitalier Henri Laborit

Recruiting

Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation (tDCS-IDSDEP)

Depression and Suicide

France
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
MercyOne Des Moines Medical Center

Completed

Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department

Depression | Suicidal Ideation | Depression and Suicide | Depression Severe | Depression Acute

United States
Sheppard Pratt Health System
COMPASS Pathways

Recruiting

The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation

Suicidal Ideation | Treatment Resistant Depression

United States
Mayo Clinic
National Institute of Mental Health (NIMH)

Recruiting

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

Suicidal Ideation | Major Depressive Disorder

United States
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Ketamine in the Treatment of Suicidal Depression

Suicidal Ideation | Major Depressive Disorder

United States
University of Alabama at Birmingham
Ortho-McNeil Janssen Scientific Affairs, LLC; American Foundation for Suicide...

Completed

Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation (AFSP)

Suicidal Ideation | Major Depressive Disorder

United States
David Lynch Foundation

Not yet recruiting

Transcendental Meditation and PTSD

Suicidal Ideation | Depressive Symptoms | Alcohol Use, Unspecified | Ptsd
University of Pittsburgh
National Institute of Mental Health (NIMH); Kaiser Foundation Research Institute

Completed

BRITEPath- Phase 2

Depression | Suicidal Ideation

United States
Massachusetts General Hospital

Withdrawn

Intranasal Ketamine for Late-Life Depression and Suicidal Ideation

Depression | Suicidal Ideation | Suicide
National Institute of Mental Health (NIMH)

Completed

Assessing Treatment Emergent Suicidal Ideation in Patients With Major Depression (SAMS)

Depression

United States
Asan Medical Center

Unknown

Identification of Genetic Markers and Predictors of Antidepressant-induced Suicidality in Youth Depression

Depression | Suicidal Ideation

Korea, Republic of
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Paroxetine/Bupropion in Depression With Suicide Attempt or Thoughts: fMRI Study

Depression | Suicidal Ideation

United States
Hallym University Medical Center
Bundang CHA Hospital; Myongji Hospital

Unknown

Suicidal Ideation and Behavior in Korean Adolescents With Depression

Depression

Korea, Republic of
University of Calgary
University of Alberta

Not yet recruiting

iTBS+D-Cycloserine for Youth Suicide

Suicidal Ideation | Suicide, Attempted | Depression, Anxiety
Washington University School of Medicine
American Foundation for Suicide Prevention

Enrolling by invitation

Nitrous Oxide- Suicidal Ideation

Depression | Mood Disorders | Suicidal Ideation | Major Depressive Disorder

United States
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Active, not recruiting

IM Ketamine vs Midazolam for Suicidal ER Patients

Suicidal Ideation | Depression, Unipolar | Depression, Bipolar

United States
University of Alabama at Birmingham
Janssen Pharmaceuticals

Completed

Risperidone and Suicidality in Major Depressive Disorder

Depression

United States
University of Pennsylvania

Completed

Engaging Suicidal Patients in Mental Health Treatment

Depression | Suicidal Ideation | Suicide | Mental Health Impairment | Suicidal

United States
Abarbanel Mental Health Center
Ministry of Health, Israel

Unknown

A Double-Blind Study of Buprenorphine Treatment of Acute Suicidality

Depression | Suicidal Ideation | Suicidal Action

Israel
Janssen Research & Development, LLC

Completed

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Major Depressive Disorder

United States
Massachusetts General Hospital

Completed

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

Major Depressive Disorder

United States
Clarigent Health
Children's Hospital Medical Center, Cincinnati; University of Cincinnati

Completed

Classification and Assessment of Mental Health Performance Using Schematics (CAMPUS)

Suicide Ideation | Suicidal Intention | Suicide and Depression

United States
Technische Universität Dresden

Unknown

Randomized, Placebo-controlled Multicenter Trial of Lithium Plus Treatment as Usual (TAU) for Acute Suicidal Ideation and Behavior in Patients With Suicidal Major Depressive Episode

Depression | Suicidal Ideation/Behavior

Germany
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH)

Recruiting

WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt

Depression | Suicidal Ideation | Suicide, Attempted

United States

Clinical Trials on Suicidal Depression

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CROs in Mongolia

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