Clinical Trials on Surgical Condition

Total 438304 results

University of Southern California
National Cancer Institute (NCI)

Recruiting

7T MRI Scan for the Early Detection of Melanoma Brain Metastases

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
I.M. Sechenov First Moscow State Medical University

Recruiting

Metabolic Disorders and Vertigo

Vestibular Migraine | Meniere Disease | Vestibular Neuritis | Benign Paroxysmal Positional Vertigo (BPPV) | Central Positional Vertigo

Russian Federation
University of Calgary
The Hospital for Sick Children; CHU de Quebec-Universite Laval; McMaster University and other collaborators

Recruiting

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Radiation Toxicity | Radiation Exposure | DIPG | Brain Tumor, Pediatric, Recurrent | Brain Tumor, Pediatric | Brain Tumor, DIPG

Canada
Baylor College of Medicine
Children's Hospital of Philadelphia; Children's Hospital Colorado; Seattle Children... and other collaborators

Recruiting

Liver Disease in Urea Cycle Disorders

Ornithine Transcarbamylase Deficiency | Urea Cycle Disorder | Argininosuccinic Aciduria | Hyperargininemia | Citrullinemia 1 | ARGI Deficiency | ASL Deficiency | ASS Deficiency

United States
Universitätsklinik für Neurologie, Innsbruck
Medical University Innsbruck; University of Erlangen-Nürnberg, Germany; University... and other collaborators

Recruiting

Mobility in Atypical Parkinsonism: a Trial of Physiotherapy (Mobility_APP)

Parkinson Disease | Progressive Supranuclear Palsy | Multiple System Atrophy, Parkinson Variant (Disorder)

Austria
BDH-Klinik Hessisch Oldendorf

Recruiting

Prognostic Factors to Regain Consciousness

Stroke | Traumatic Brain Injury | Neurologic Disorder | Disorder of Consciousness | Hypoxic-Ischemic Encephalopathy

Germany
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies (PROMETEO)

Obesity | Diabetes | Fatty Liver | Metabolic Syndrome | Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Liver Cancer | NAFLD - Nonalcoholic Fatty Liver Disease | HCC - Hepatocellular Carcinoma

Italy
Massachusetts General Hospital
Dana-Farber Cancer Institute

Recruiting

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Melanoma Stage IV | Melanoma Stage III | Drug Toxicity | Immune-related Adverse Event | Skin Cancer Stage III | Skin Cancer Stage IV | Drug-Induced Colitis

United States
Massachusetts General Hospital
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

TMS for the Treatment of Primary Progressive Aphasia

Logopenic Variant Primary Progressive Aphasia | Non-fluent Variant Primary Progressive Aphasia | Semantic Variant Primary Progressive Aphasia

United States
Centre Hospitalier National d'Ophtalmologie des...

Recruiting

Multimodal Ophthalmic Imaging (IMA-MODE)

Stroke | Glaucoma | Hypertension | Diabetes | Retinal Degeneration | Macular Edema | Retinitis Pigmentosa | Trauma | Dry Eye | Keratoconus | Retinal Detachment | Corneal Dystrophy | Vascular Inflammation | Macular Dystrophy | Maculopathy, Age Related

France
Case Comprehensive Cancer Center

Recruiting

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

Small-cell Lung Cancer | Large Cell Neuroendocrine Carcinoma of the Lung | Extrapulmonary Small Cell Carcinoma

United States
Institut Claudius Regaud

Recruiting

Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group (MIRAS)

Soft Tissue Sarcoma | Perivascular Epithelioid Cell Neoplasms | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Desmoplastic Small Round Cell Tumor | Clear Cell Sarcoma | Sclerosing Epithelioid Fibrosarcoma | Low Grade Fibromyxoid Sarcoma | Malignant Solitary Fibrous Tumors | Epithelioid Hemangioendothelioma

France
Brigham and Women's Hospital
Charite University, Berlin, Germany; Stanford University

Recruiting

Biomarkers for Circadian Timing in Healthy Adults

Sleep Disorders, Intrinsic | Sleep Wake Disorders | Sleep Disorders, Circadian Rhythm | Advanced Sleep Phase Syndrome (ASPS) | Delayed Sleep Phase Syndrome | Shift-Work Sleep Disorder | Delayed Sleep Phase | Non-24 Hour Sleep-Wake Disorder | Advanced Sleep Phase Syndrome | Advanced Sleep Phase | Irregular... and other conditions

United States
Mayo Clinic

Recruiting

The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech (SLD4T)

Primary Progressive Aphasia | Apraxia of Speech | Primary Progressive Nonfluent Aphasia | Non-fluent Aphasia

United States
University of Alabama at Birmingham
Massachusetts General Hospital

Recruiting

High Resolution Micro OCT Imaging

Covid19 | Sinusitis | Cystic Fibrosis | COPD | PCD - Primary Ciliary Dyskinesia

United States
M.D. Anderson Cancer Center

Recruiting

Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients

Multiple Endocrine Neoplasia

United States
State University of New York at Buffalo

Recruiting

Blood Collection Biorepository for Liver Disease Research

Fibrosis | Hepatitis B | Hepatitis C | Fatty Liver | Cirrhosis | Bariatric Surgery Candidate | Obesity, Childhood | Non-Alcoholic Steatohepatitis(NASH)

United States
Children's Hospital Medical Center, Cincinnati
Lymphangiomatosis and Gorham's Disease Alliance (LGDA); Klippel Trenaunay (KT)... and other collaborators

Recruiting

Identification of Biomarkers for Patients With Vascular Anomalies

Kaposiform Hemangioendothelioma | Kaposiform Lymphangiomatosis | Vascular Anomaly | Klippel Trenaunay Syndrome | Generalized Lymphatic Anomaly | Gorham-Stout Disease | Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi

United States
Mayo Clinic

Recruiting

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
University of Sao Paulo
Instituto do Cancer do Estado de São Paulo

Recruiting

Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases

Colorectal Cancer | Liver Metastases | Anal Canal Cancer | Gastrointestinal Neuroendocrine Tumors

Brazil
National Human Genome Research Institute (NHGRI)

Enrolling by invitation

Genetic Studies of Lysosomal Storage Disorders

Parkinson Disease | Gaucher Disease | Lysosomal Storage Disorders

United States
National Cancer Institute (NCI)

Active, not recruiting

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Unresectable Melanoma | Advanced Melanoma | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Jazz Pharmaceuticals

Active, not recruiting

Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Tuberous Sclerosis Complex | Dravet Syndrome | Lennox Gastaut Syndrome

United States
Columbia University
New York Obesity and Nutrition Research Center

Completed

Novel Mediators of the Lipodystrophy and Metabolic Consequences of Cushing's Disease

Cushing's Syndrome

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI); University of California... and other collaborators

Enrolling by invitation

SHADES Mechanistic Trial (SHADES)

Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Stroke | Sleep Disorder | Insomnia | Sleep Disturbance | Metabolic Disease | Autonomic Dysfunction | Insomnia Chronic | Systemic Inflammatory Response | Insomnia, Primary

United States
Organon and Co

Completed

The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726)

Sleep Disorder | Obstructive Sleep Apnea | Perennial Allergic Rhinitis
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Lung Adenocarcinoma | Lung Large Cell Carcinoma | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Minimally Invasive Lung Adenocarcinoma | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Lung Squamous Cell Carcinoma | Lung Adenosquamous Carcinoma

United States
University of Florida
ALS Association

Active, not recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Frontotemporal Dementia | C9orf72 Amyotrophic Lateral Sclerosis (ALS)

United States
National and Kapodistrian University of Athens
Ioulia And Irene Tseti Pharmaceutical Laboratories S.A.

Completed

Assessing the Efficacy of a Hydrogen Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief

Postoperative Pain | Dental Plaque | Wound Heal | Sjogren's Syndrome | Mouth Dryness | Gingival Inflammation | Biopsy Wound | Oral Dryness | Mouth; Wound

Greece
Emalex Biosciences Inc.
Psyadon Pharma

Terminated

Ecopipam Treatment of Self-Injurious Behavior in Subjects With Lesch-Nyhan Disease

Lesch-Nyhan Disease | Self-injurious Behavior

Spain, United States
Neuromed IRCCS

Enrolling by invitation

Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation (NeuroPsyc) (NeuroPsyc)

Stroke | Epilepsy | Multiple Sclerosis | Parkinson Disease | Dementia

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer

Thyroid Gland Medullary Carcinoma | Differentiated Thyroid Gland Carcinoma | Malignant Adrenal Gland Pheochromocytoma | Malignant Paraganglioma

United States
Mayo Clinic
Sleep Number, Inc.

Active, not recruiting

Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation

Coronary Artery Disease | Sleep Disorder; Breathing-Related | Sleep Disorder; Insomnia Type

United States
Oded Meiron
Neurosteer Ltd.

Completed

Excitatory Prefrontal Weak Current Stimulation in Vegetative Patients (VEG-TDCS)

Disorder of Consciousness | Trauma, Brain | Vegetative State | MMN | Modification of Cognitive Status Indication | Anoxic Brain Damage | EEG; Paroxysms, Occipital, Epilepsy of Childhood | Cortical Atrophy

Israel
Aesculap AG

Active, not recruiting

Cemented TrendHip® - Multicenter PMCF Study on Total Indications (TRESTI)

Rheumatoid Arthritis | Hip Dysplasia | Fractures, Hip | Necrosis, Femur Head | Coxarthrosis; Primary | Coxarthrosis; Post-Traumatic

Germany
Gregory K. Friedman, MD
Memorial Sloan Kettering Cancer Center; United States Department of Defense; Food... and other collaborators

Completed

HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors

Glioblastoma | Malignant Glioma | PNET | Anaplastic Astrocytoma | Embryonal Tumor | Supratentorial Neoplasms, Malignant | Cerebral Primitive Neuroectodermal Tumor

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Brain Hemorrhage and Functional Outcome in Stroke Patients With CAA Features on Pre-thrombolysis MRI Treated With Intravenous Thrombolysis (Thrombolysis in CAA) ( Thromb in CAA ) (Thromb in CAA)

Stroke | Hemorrhage | Cerebral Amyloid Angiopathy

France
VA Office of Research and Development

Active, not recruiting

Pilot rTMS for AUD+mTBI (TMS_AUD+mTBI)

Alcohol Use Disorder | Post-traumatic Stress Disorder | Mild Traumatic Brain Injury

United States
University of Nebraska
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer

Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Invasive Breast Carcinoma | Stage IA Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | HER2/Neu Positive | Progesterone... and other conditions

United States
University of Bordeaux

Completed

Delay to Diagnosis in Digestive Cancerology by the General Practitioner Related to Covid-19 Pandemic Confinement

Advanced Cancer | Pandemic, COVID-19 | Diagnosis | Neoplasms, Colorectal | Neoplasms Pancreatic | General Practitioner | Neoplasm, Liver

France
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

Epstein-Barr Virus Infection | Stage III Nasopharyngeal Carcinoma | Stage IVA Nasopharyngeal Carcinoma | Stage IVB Nasopharyngeal Carcinoma | Stage II Nasopharyngeal Carcinoma

United States, Canada, Taiwan, Puerto Rico, Australia, Hong Kong, Singapore, China
Erasmus Medical Center
Stichting TAAI

Active, not recruiting

TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era (TERRIFIC-MILE)

Lung Diseases | Cystic Fibrosis | Infections, Bacterial | Congenital Disorders | Lung Inflammation | Lung Infection | Lung Disease; Cystic | Lung Disease; Cystic, Congenital | Inflammation Lungs | Exacerbation, Symptom

Netherlands
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation... and other collaborators

Completed

Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke (SMARTIES)

Stroke | Sleep Apnea Syndromes | Restless Legs Syndrome | Ischemic Attack, Transient | Sleep Disorders

Canada
City of Hope Medical Center

Active, not recruiting

Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers

Lung Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Caregiver | Malignant Digestive System Neoplasm | Adult Liver Carcinoma

United States
National Cancer Institute (NCI)

Terminated

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Lung Cancer | Carcinoma, Esophageal | Malignant Pleural Mesotheliomas

United States
Rutgers, The State University of New Jersey
Rutgers Cancer Institute of New Jersey; Elekta Limited; Cianna Medical, Inc.

Completed

Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery (TRIUMPH-T)

Invasive Breast Carcinoma | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Estrogen Receptor Positive | Progesterone Receptor Positive | Ductal Breast Carcinoma In Situ

United States
Randy Kardon

Terminated

LSFG-SKIN, Laser Speckle Flowgraphy

Heart Failure | Stroke | Pain | Multiple Sclerosis | Hypertension | Burns | Migraine | Uveitis | Headache | Intracranial Hemorrhages | Radiation Injuries | Chemotherapy Effect | Autonomic Neuropathy | TIA | Scleritis | Vascular Ischemia

United States
University Hospital, Tours
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Health cAre woRkers exposeD to COVID-19 (HARD-COVID19)

Depression | Burnout, Professional | Post Traumatic Stress Disorder

France
National Neuroscience Institute
Nanyang Technological University; Institute for Infocomm Research; Institute... and other collaborators

Active, not recruiting

[BrainConnexion] - Neurodevice Phase I Trial

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Tetraplegia | Tetraplegia/Tetraparesis | Locked-in Syndrome

Singapore
Zimmer Biomet

Terminated

Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Femur Fracture | Trochanteric Fractures | Pseudarthrosis | Pseudoarthrosis | Functional Deformities | Revision of Endoprosthesis-treated Hips | Fracture, Proximal Humeral | Provision of Non-endoprosthetic Previous Operations of the Hip Joint (e.g... and other conditions

Germany

Clinical Trials on Surgical Condition

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burundi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations