Clinical Trials on Symptomatic Gastroespohageal Reflux Disease

Total 2170 results

Novartis

Completed

A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroespohageal Reflux Disease

United States
Phathom Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily

Helicobacter Pylori Infection | Heartburn | Erosive Esophagitis | Symptomatic Nonerosive Gasroesophageal Reflux Disease

United States
Hanmi Pharmaceutical Company Limited

Completed

Safety to Evaluate the Efficacy and Safety of HIP1601 in Patients With Non Erosive Reflux Disease

Non-erosive Gastroesphageal Reflux Disease

Korea, Republic of
Yonsei University

Completed

Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease

Non-erosive Gatroesophageal Reflux Disease

Korea, Republic of
Eisai Inc.

Completed

Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)

United States
GlaxoSmithKline

Completed

Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg.

Reflux, Gastroesophageal | Gastroesophageal Reflux Disease

Australia
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD?

Gastroesophageal Reflux Disease | GERD | Acid Reflux | Reflux

United States
AstraZeneca

Completed

A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)
Takeda

Terminated

The CONQUEST-Study. Evaluation of Clinical Endpoints for Treatment-induced Changes in GERD-related Symptoms (BY1023/NL511)

Gastroesophageal Reflux Disease | Non-erosive Reflux Disease

Switzerland, Netherlands
Mansoura University

Withdrawn

The Potential Therapeutic Effect of Melatonin in Gastro-Esophageal Reflux Disease

Gastroesophageal Reflux Disease
Cliniques universitaires Saint-Luc- Université...

Unknown

Determinants of Efficacy of EsophyX Treatment in Gastro-Esophageal Reflux Disease

Gastroesophageal Reflux Disease

Belgium
GlaxoSmithKline

Completed

A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.

Reflux, Gastroesophageal | Gastroesophageal Reflux Disease

Australia
Vanderbilt University Medical Center

Completed

Assessment of Esophageal Epithelium Integrity With Mucosal Impedance

Gastroesophageal Reflux Disease (GERD) | Non-erosive Reflux Disease (NERD)

United States
King Chulalongkorn Memorial Hospital

Completed

Diagnostic Value of Flexible Spectral Imaging Color Enhancement (FICE) Plus Probe-based Confocal Laser Endomicroscopy (pCLE) for Minimal Change Esophageal Reflux Disease (MERD) Diagnosis

Gastroesophageal Reflux Disease

Thailand
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol (RESULT)

Gastroesophageal Reflux Disease (GERD) | Reflux

United States, Canada
Scandinavia Pharma

Recruiting

Epi-GERD Study: Epidemiological Evaluation in Patients With Gastro-Esophageal Reflux Disease (GERD) (Epi-ERGE)

Gastroesophageal Reflux Disease

Colombia
Klinikum Garmisch-Patenkirchen

Not yet recruiting

ARMA (Antireflux Mucosa Ablation) in Patients With Chronic Refractory Reflux Disease (ARMA)

Reflux, Gastroesophageal | Gastro-esophageal Reflux

Germany
Pfizer

Terminated

Efficacy And Safety Of PF-00885706 For The Relief Of Symptoms In Subjects With Gastro-esophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

Brazil, Germany, Korea, Republic of, Belgium, Spain, Slovakia, France
Torax Medical Incorporated

Completed

The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease (CALIBER)

GERD Gastroesophageal Reflux Disease

United States
University Hospital Muenster

Completed

One-stop-shop Endoscopy in Reflux-patients: Evaluation of ENT and GI Features (ENTGI-reflux)

Reflux, Gastroesophageal | Reflux Disease | Reflux, Laryngopharyngeal

Germany
EndoStim Inc.

Terminated

An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Reflux

Gastroesophageal Reflux | Reflux, Gastroesophageal | Gastroesophageal Reflux Disease (GERD) | Acid Reflux

United States, Belgium, Netherlands, United Kingdom
Lexington Health Incorporated

Active, not recruiting

Transoral Fundoplication Prior to Sleeve Gastrectomy Versus RNY Gastric Bypass on GERD Symptoms in Bariatric Patients

Gastroesophageal Reflux Disease

United States
Sanofi

Completed

Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects

Gastroesophageal Reflux Disease

United Kingdom
Shire

Terminated

An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients

Gastroesophageal Reflux Disease

United Kingdom, Switzerland, Netherlands, Belgium, France, Germany
American Gastroenterological Association
EndoGastric Solutions

Terminated

Registry to Compare Two Surgical Treatments for GERD (STAR Registry)

GastroEsophageal Reflux Disease

United States
Krankenhaus Barmherzige Schwestern Linz

Completed

Prospective Trial on the Clinical Feasibility of a New Full Thickness Endoscopic Plication Device for Patients With GERD.

Gastroesophageal Reflux Disease

Austria
EndoStim Inc.

Unknown

Effect of Long-Term Electrical Stimulation on LES Pressure and Esophageal Acid Exposure in Patients With GERD

Gastroesophageal Reflux Disease

Chile, Colombia, India, Mexico, Netherlands, New Zealand, United Kingdom
AstraZeneca

Completed

The Use of International GerdQ Questionnaire (GERDq)

Gastroesophageal Reflux Disease

Russian Federation
Nycomed

Completed

Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease (PARADE)

Gastroesophageal Reflux Disease

Germany
AstraZeneca

Completed

Esomeprazole in PPI Failures - IMPROVE

Gastroesophageal Reflux Disease

Sweden
Rabin Medical Center

Unknown

SThe Effects of Melatonin on GERD Symptoms

Gastroesophageal Reflux Disease

Israel
AstraZeneca

Completed

Survey to Describe Impact of Reflux Disease on Everyday Life in GERD Patients Before and After 4 Weeks Treatment.

Gastroesophageal Reflux Disease

Vietnam
Karolinska Institutet

Completed

Comparison of Total and Partial Fundoplication During Surgery of Patients With Gastroesophageal Reflux Disease (RefluxII)

Reflux, Gastroesophageal
Daewoong Pharmaceutical Co. LTD.

Recruiting

Study to Evaluate the Efficacy and Safety of FEXUCLUE Tablet

Gastroesophageal Reflux Disease

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Recruiting

Study to Evaluate the Improvement Effect on Subjective Symptom of FEXUCLUE Tab

Gastroesophageal Reflux Disease

Korea, Republic of
Yungjin Pharm. Co., Ltd.
Seoul National University Hospital

Completed

A Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of YPI 011 to Rabeprazole in Healthy Adult Subjects

Gastroesophageal Reflux Disease

Korea, Republic of
Indiana University

Enrolling by invitation

Transoral Incisionless Fundoplication Database Repository (TIF) (TIF)

Gastroesophageal Reflux Disease

United States
Sanofi

Completed

PH Metry Study to Compare the Antacid Activity of Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects

Gastroesophageal Reflux Disease

France
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazole

Gastroesophageal Reflux Disease

Korea, Republic of
Mansoura University Children Hospital

Completed

Role of Pepsin Assay in Wheezy Infants

Gastroesophageal Reflux Disease
Otsuka Pharmaceutical Co., Ltd.

Completed

A Trial of C13-CAC Breath Test in PPI Resistant GERD Patients

Gastroesophageal Reflux Disease

Japan
Nantes University Hospital

Completed

Stretta In Reflux Uncontrolled by IPP (SIRUP)

Gastroesophageal Reflux Disease

France
Emory University
Children's Healthcare of Atlanta

Completed

Cardiaplication: A Novel Antireflux Operation

Gastroesophageal Reflux Disease
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Comparing Clinical Efficacy of One-Week Dual Delayed-Release Dexlansoprazole and Esomeprazole for GERD Grade A and B

Gastroesophageal Reflux Disease
Vanderbilt University Medical Center

Completed

Feasibility of Placing Bravo PH Capsule in Proximal Esophagus (bravo)

Gastroesophageal Reflux Disease

United States
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
Oxford University Hospitals NHS Trust

Completed

Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children

Gastroesophageal Reflux Disease

United Kingdom
Takeda

Withdrawn

Phase 1 Dexlansoprazole Delayed-Release Capsules for Acid-Related Disorders in Infants Aged 1 to 11 Months

Pediatric Gastroesophageal Reflux Disease

United States, Italy, Israel, Mexico, Poland
Wake Forest University Health Sciences
Takeda

Completed

Correlation of Oropharyngeal Pepsin and Gastroesophageal (GE) Reflux (Pepsin)

Gastroesophageal Reflux Disease (GERD)

United States
AstraZeneca
i3 Innovus

Completed

Partial Response to Proton Pump Inhibitors (PPI) Treatment: The Cost to Society and the Burden to the Patient - a Study in the US (REMAIN)

Gastroesophageal Reflux Disease (GERD)

United States

Clinical Trials on Symptomatic Gastroespohageal Reflux Disease

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