Clinical Trials on Systemic Inflammatory Response

Total 191293 results

Peking Union Medical College Hospital

Unknown

Reducing Elevated Heart Rate in Patients With Severe Sepsis by Ivabradine (REHSI)

Sepsis, Severe
Christiana Care Health Services

Completed

Preemptive Resuscitation for Eradication of Septic Shock

Sepsis | Severe Sepsis

United States
Groupe Hospitalier Paris Saint Joseph
Institut Pasteur; Agency for Science, Technology and Research

Completed

Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis (CASPASEs)

Severe Sepsis

France
Changi General Hospital
Singhealth Foundation

Completed

Glutamine Supplementation in Critically Ill Patients With Severe Sepsis (CGH-GLU)

Severe Sepsis

Singapore
Radboud University Medical Center

Completed

Effects of Vasopressors on Immune Response

Endotoxemia

Netherlands
Fujian Provincial Hospital

Completed

The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis

Severe Sepsis
University of Oxford
National Institute of Allergy and Infectious Diseases (NIAID); FHI 360; Social...

Completed

An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast Asia (SEA050)

Sepsis | Severe Sepsis

Thailand, Indonesia, Vietnam
Karolinska Institutet
Region Stockholm; Svenska militärläkarföreningen

Terminated

Optimization of Fluid Therapy in Sepsis by a Passive Leg Raising Test (OFTaPLR)

Shock, Septic

Sweden
Radboud University Medical Center

Completed

Ticagrelor in Human Endotoxemia Response to Human Endotoxemia

Endotoxemia

Netherlands
Rijnstate Hospital
Stichting Vrienden van het Alysis Leerhuis

Withdrawn

Procalcitonin Guided Versus Conventional Antibiotic Therapy in Patients With Sepsis in the ICU

Sepsis | Intensive Care

Netherlands
National Institute of Allergy and Infectious Diseases...

Terminated

Detoxified J5 Core Glycolipid/ Group B Meningococcal Outer Membrane Protein Vaccine for Gram-negative Bacterial Sepsis Administered With and Without Synthetic CPG Oligodeoxynucleotide 7909 Adjuvant

Bacterial Sepsis

United States
Erasmus Medical Center

Unknown

Peripheral Perfusion Targeted Fluid Management

Sepsis | Severe Sepsis

Netherlands
University of Salerno
Federico II University

Unknown

Angiotensin II Antagonist in Severe Sepsis (SartSep)

Severe Sepsis

Italy
Gruppo Italiano per la Valutazione degli Interventi...
BELLCO S.r.l., Mirandola (MO), ITALY

Terminated

COMPACT - COMbining Plasma-filtration and Adsorption Clinical Trial

Shock, Septic

Italy
Agennix

Completed

Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis

Severe Sepsis

United States, Canada, France, Germany, Spain
Sun Yat-sen University

Completed

Efficacy of Thymosin alpha1 for Severe Sepsis (ETASS)

Severe Sepsis

China
Eli Lilly and Company

Completed

Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)

Severe Sepsis

United States, Belgium, Spain, France, Finland, Germany, Canada, United Kingdom, Puerto Rico
Radboud University Medical Center

Completed

A Possible Therapeutic Role for Adenosine During Inflammation

Endotoxemia

Netherlands
Li Shin Hospital

Completed

Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis

Severe Sepsis

Taiwan
Radboud University Medical Center

Completed

Effect of Selective iNOS Inhibition During Human Endotoxemia

Endotoxemia

Netherlands
The Cleveland Clinic

Not yet recruiting

Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator

Shock, Septic
West China Hospital

Recruiting

The Impact of Sepsis on Long-term Outcomes in Critical Ill Children With Sepsis

Sepsis | Children, Only

China
Ain Shams University

Not yet recruiting

PSP as Indicator for Urinary Sepsis in ICU

Urinary; Sepsis
Tunis University

Recruiting

Early Administration of Norepinephrine in Sepsis (EA-NE-TUN)

Sepsis, Severe

Tunisia
Huashan Hospital

Recruiting

Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis

Sepsis | Septic Shock

China
The George Institute for Global Health, Australia

Completed

Days Alive and Out of Hospital for Patients With Sepsis

Sepsis | Septic Shock

Australia
University Hospital Muenster

Completed

Glycocalyx and Microcirculation in Sepsis

Sepsis

Germany
University of Milano Bicocca

Completed

Lotta Alla Sepsi Ospedaliera - Fighting Hospital Sepsis

Severe Sepsis

Italy
Centre Hospitalier Universitaire de Nīmes

Completed

Personalized Dose Optimization of Amikacin Guided by Pharmacokinetic Modeling Software in Patients With Septic Shock (AMINO BESTDOSE)

Shock, Septic

France
Cairo University

Completed

Effect of Probiotics on Cytokines in Sepsis in Children

Sepsis, Severe

Egypt
University of Florida
National Institutes of Health (NIH); National Institute of General Medical...

Active, not recruiting

Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS

Sepsis

United States
Lawson Health Research Institute
Schulich School of Medicine and Dentistry

Completed

Targeted Exercise Intervention to Reduce Morbidity and Mortality in Sepsis (TERMS)

Severe Sepsis

Canada
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Completed

A Study of Exosome Proteomics and Hemodynamics in Sepsis

Hemodynamic Instability | Autophagy

Taiwan
University of Sao Paulo

Suspended

Neuromuscular Electrical Stimulation and Septic Shock

Shock, Septic

Brazil
Radboud University Medical Center

Completed

The Effects of Acetylsalicylic Acid on Immunoparalysis Following Human Endotoxemia (SALYCENDO)

Endotoxemia

Netherlands
Alexander Flannery, 859-323-4011

Terminated

Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock

Shock, Septic

United States
Inotrem

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of 3 Doses of MOTREM in Patients With Septic Shock

Shock, Septic

Belgium, France, Netherlands, Spain
University of Arkansas

Withdrawn

NOrepinephrine and VasoprEssin Versus Norepinephrine aLone in Critically Ill Patients With Septic Shock (NOVEL)

Shock, Septic

United States
University of Oxford
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand

Sepsis | Severe Sepsis

Thailand
Ramathibodi Hospital

Completed

Balanced Salt Solution VS. Normal Saline Solution in Septic Shock

Sepsis | Shock, Septic

Thailand
Centre Hospitalier Universitaire, Amiens

Unknown

Descriptive Study of the Evolution in Proportion of Regulatory B Lymphocytes in Patients Hospitalized in Intensive Care for Severe Sepsis (DELyBREG)

Severe Sepsis

France
Klinikum St. Georg gGmbH
University of Halle Medical Faculty

Terminated

Alterations of Immunologic Mediators During Severe Sepsis (LAVISS_01)

Severe Sepsis

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

The Role of the Gut Microbiota in the Systemic Immune Response During Human Endotoxemia (MISSION-2)

Endotoxemia

Netherlands
Stanford University

Completed

Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert

Severe Sepsis

United States
Rutgers, The State University of New Jersey

Completed

The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers

Infections

United States
King Abdullah International Medical Research Center

Unknown

Effectiveness of Different Interventions for Implementing Surviving Sepsis Campaign (SSC) Guidelines on Compliance and Mortality: Systematic Review and Meta-analysis

Sepsis | Septic | Septicemia
Corporacion Parc Tauli

Unknown

Monitoring Resuscitation in Severe Sepsis and Septic Shock

Hemodynamics

Spain
Maastricht University Medical Center
Novartis Medical Nutrition

Completed

Dose-response Study of Arginine Supplementation in Severe Sepsis

Sepsis | Septic Shock
Agennix

Suspended

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis (OASIS)

Severe Sepsis

United States, Spain, Belgium, France, United Kingdom, Canada, Israel, Germany, Denmark, Netherlands
Charite University, Berlin, Germany
Sysmex Europe GmbH

Completed

Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU

Sepsis | SIRS

Germany

Clinical Trials on Systemic Inflammatory Response

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