Clinical Trials on Telomere Length

Total 207 results

Helsinki University Central Hospital
University of Helsinki; City of Espoo

Completed

Geriatric Assessment and Intervention for Older Patients With Frailty in the Emergency Department (GAOPS)

Quality of Life | Frail Elderly Syndrome | Fall | Hospital Readmission | Length of Stay | Patient Admission

Finland
Zhejiang University

Completed

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Quality of Life | Complications | Adverse Drug Event | Length of Stay | Hospital Costs

China
Odense University Hospital

Completed

Advantages and Disadvantages of Long Term Sedation in Intensive Care Unit Patients

Critical Illness | Respiration, Artificial | Length of Stay | Intensive Care Units

Denmark
Oregon Health and Science University
Society of Family Planning

Completed

The Effects of a Prostaglandin Inhibitor on Ovulation and the Menstrual Cycle

Ovulation (Follicular Rupture Yes/no) | Menstrual Cycles (Total Length, Bleeding Days) | Gonadotropin and Ovarian Hormone Levels (FSH, LH, E2, P)

United States
Makassed General Hospital

Completed

Normal Saline vs Hypertonic Saline in the Treatment of Bronchiolitis

Length of Hospital Stay

Lebanon
University of California, San Francisco

Completed

Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain

Postoperative Pain | Postoperative Delirium | Opioid Use | Hospital Length of Stay

United States
University of Calgary
Alberta Health services; University of Alberta; Covenant Health

Enrolling by invitation

Alberta Collaborative QI Strategies to Improve Outcomes of Moderate and Late Preterm Infants (ABC-QI Trial) (ABC-QI)

Length of Stay

Canada
Hospital Universitari Vall d'Hebron Research Institute

Completed

Postoperatory Recovery in Advanced Ovarian Cancer, Fast-Track Protocol vs. Classical Management (PROFAST)

Median Length of Stay | Readmission Rate | Surgery Related Complications Rate | Cost Per Patient Rate

Spain
Peking University First Hospital

Not yet recruiting

Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

Prostate Cancer | Enhanced Recovery After Surgery | Prostatectomy | Prehabilitation | Length of Hospital Stay

China
National Yang Ming University

Completed

Additional Gluteal Control Training for Low Back Pain With Functional Leg Length Inequality

Low Back Pain, Recurrent

Taiwan
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Geriatric-CO-mAnagement for Cardiology Patients in the Hospital (G-COACH)

Cardiovascular Diseases | Delirium | Frail Elderly | Activities of Daily Living | Geriatric Assessment | Length of Stay | Health Services for the Aged

Belgium
University of North Carolina, Chapel Hill

Completed

Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms

Osteoarthritis, Knee | Osteoarthritis, Hip | Leg Length Inequality

United States
Bayside Health

Completed

Formation and Severity of Pressure Ulcers Associated With 4% Albumin vs. 0.9% Sodium Chloride

Length of ICU Stay | Pressure Ulcer, Area | Pressure Ulcer, Grade | Albumin Level | Risk Score

Australia
University Hospital, Geneva
Meyer Jeremy. PhD. Co-investigator. University Hospital, Geneva.; Peloso Andrea... and other collaborators

Not yet recruiting

Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy (CiPNT/SSI)

Surgical Site Infection | Hematoma | Seroma | Length of Stay
University of Vermont Medical Center

Completed

A Quality Initiative to Improve Glycemic Control in Diabetic and Non-Diabetic Insulin Study

Cardiac Complications | Cost | Length of Stay | Surgical Site Infections | Glycemic Control

United States
Shriners Hospitals for Children

Completed

Botox Injection for Lower Extremity Lengthening and Deformity Correction Surgery (BOLLD)

Lower Extremity Deformities, Congenital | Unequal Length of Limbs; Congenital

Canada, United States
University of Sao Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Nandrolone Decanoate in the Treatment of Telomeropathies

Idiopathic Pulmonary Fibrosis | Aplastic Anemia | Bone Marrow Failure Syndromes | Telomere Shortening

Brazil
Bangkok Metropolitan Administration Medical College...

Completed

BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy

Renal Insufficiency | Cardiac Event | Hospital Length of Stay | Intradialytic Hypotension

Thailand
Medical University of Vienna
Surgebright Gmbh

Recruiting

Human Bone Graft in Epiphysiodesis

Leg Length Differences | Primordial Gigantism

Austria
University Children's Hospital Basel
Swiss Federal Institute of Technology; Bern University of Applied Sciences

Completed

Spine Biomechanics During Gait Following Lower Extremity Treatment in Different Patient Groups

Cerebral Palsy | Leg Length Inequality

Switzerland
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

The MODE Trial: Planned Caesarean Section Versus Induction of Labour for Women With Class III Obesity (MODE)

Obesity | Pregnancy, High Risk | Cesarean Section Complications | Obesity Complicating Childbirth | Labor Onset and Length Abnormalities

Canada
Services Hospital, Lahore

Completed

Comparison of Outcomes After Laparoscopic Versus Open Appendectomy in Acute Appendicitis

Pain, Postoperative | Length of Stay | Appendectomy

Pakistan
Nantes University Hospital

Completed

Neurological Fate, Prematurity and Genetic Susceptibility Factors (GENIMOC)

Polymorphism, Restriction Fragment Length | Premature | Infertility of Cervical Origin

France
Services Hospital, Lahore

Completed

Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique

Length of Stay | Operative Time | Hemorrhoidectomy | Third Degree Hemorrhoids | Fourth Degree Hemorrhoids | Postoperative,Pain

Pakistan
Medical University of Vienna

Completed

Compression Treatment of Superficial Vein Thrombosis

Quality of Life | Pain | Erythema | Thrombus Length
Western Galilee Hospital-Nahariya

Not yet recruiting

Breast Stimulation vs. Low Dose Oxytocin Augmentation for Labor Induction

Labor Onset and Length Abnormalities | Uterine Rupture | Birth; Induced

Israel
Universidade Federal de Santa Maria

Completed

The Impact of Early Mobilization Protocol in Patients in the ICU

Quality of Life | Muscle Weakness | ICU Length of Stay | Weaning Acceleration | Muscle Thickness of the Quadriceps Femoris

Brazil
Sheffield Children's NHS Foundation Trust

Withdrawn

Botox Clinical Trial

Foot Deformities | Leg Length Inequality

United Kingdom
National Cancer Institute (NCI)

Completed

Needs Assessment for Individuals and Families Affected by Dyskeratosis Congenita (DC) and Related Telomere Biology Disorders (TBD)

Dyskeratosis Congenita | Telomere Biology Disorders

United States
Baylor St. Luke's Medical Center

Completed

Non-ventilated Prone Positioning in the COVID-19 Population

COVID-19 | Length of Stay | Oxygenation | Proning

United States
Ramathibodi Hospital
Arkom Nongnuch; Supawadee Suppadungsuk; Adisorn Pathumarak

Recruiting

Efficacy of Convection-based HDF Compare With Diffusion-based HD in Sepsis-associated AKI

Primary Outcome : Compare Percent CRP Reduction | Secondary Outcome : 30-day Mortality, Renal Recovery, Length of Hospital Stay

Thailand
University Hospital, Toulouse

Recruiting

Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia (OPPAÎ)

Pneumonia | Pneumonia, Ventilator-Associated | Length of Stay

France
Oslo University Hospital
Sophies Minde AS

Completed

Femoral Lengthening Might Impair Physical Function and Lead to Structural Changes in Adjacent Joints

Quality of Life | Osteoarthritis, Knee | Leg Length Inequality | Osteoarthritis of Hip | Leg; Lengthening

Norway
Lifespan

Completed

Evaluating the Effectiveness of Incentive Spirometry

Pneumonia | Dyspnea | Atelectasis | Respiratory Rate | Oxygen Saturation | Oxygen Requirements | FEV1 | FVC | Re-intubation | Hospital Length of Stay | Nursing Workload | Incentive Spirometry

United States
Ain Shams University

Completed

Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis

Postoperative Complications | Hemodynamics | Intraoperative Fluid Volume | Serum Lactate | Intestinal Edema | Length of the Hospital Stay | First Time to Gastrointestinal Motion

Egypt
University Hospitals Cleveland Medical Center
The Cleveland Clinic; MetroHealth Medical Center

Recruiting

Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age

Premature Birth | Pregnancy Preterm | PROM (Pregnancy) | Pregnancy Prom | PROM, Preterm (Pregnancy) | Premat Rupture Membranes Preterm Unspec to Length of Time Between Rupture/Labor

United States
National Taiwan University Hospital

Completed

The Outcome Effect of Shoe Lift for Individuals With Low Back Pain and Pronated Foot Due to Anatomical Leg Length Discrepancy

Low Back Pain | Flatfoot | Leg Length Inequality

Taiwan
Horizon Pharma USA, Inc.

Completed

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease (MITO-001)

Inherited Mitochondrial Disease, Including Leigh Syndrome

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

Severe Aplastic Anemia | Telomere Biology Disorders | Inherited Bone Marrow Failure Syndromes

United States
Ostfold Hospital Trust

Not yet recruiting

The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL) (NORWEL)

Progression | Cesarean Section Complications | Labor Complication | Labor Onset and Length Abnormalities | Experience, Life | Labor (Obstetrics)--Complications | Labor Dystocia | Apgar; 4-7 at 1 Minute

Norway
Pirogov Russian National Research Medical University

Completed

Fluid Overload and Pulmonary Function

Critical Illness | Respiratory Failure | Water-Electrolyte Imbalance | Pediatric | Esophageal Atresia | Length of Stay | Intensive Care Units

Russian Federation
Taysha Gene Therapies, Inc.

Withdrawn

A Study of the Natural Course of SURF1 Deficiency

Leigh Syndrome

United States
PTC Therapeutics
Axio Research. LLC

Completed

Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome

Leigh Syndrome

United States
Odense University Hospital
Odense Patient Data Explorative Network

Recruiting

Clonidine for Tourniquet-related Pain in Children (CLOTCH)

Toe Joint Deformity | Clubfoot | Flatfoot | Trigger Finger | Syndactyly | Hand Deformities, Congenital | Tarsal Coalition | Congenital Talipes Equinovarus | Valgus Foot Deformity | Club Foot | Polydactyly Toe | Thumb Hypoplasia | Polydactyly; Fingers | Osteomyelitis of Hindfoot | Osteomyelitis of Midfoot | Congenital Talipes... and other conditions

Denmark
PTC Therapeutics

Completed

Long-Term Safety and Efficacy Evaluation of EPI-743 in Children With Leigh Syndrome

Leigh Syndrome

United States
Aadi Bioscience, Inc.

Withdrawn

ABI-009 (Nab-sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome

Leigh Syndrome
Louisiana State University Health Sciences Center...

Completed

Asthma and Obesity Diet Versus Exercise

Physical Activity | Metabolic Syndrome | Inflammatory Response | Asthma in Children | Obesity, Childhood | Nutrition Poor | Behavior, Eating | Maternal Exposure | Molecular Biology, Restriction Fragment Length Polymorphisms | Genetic Change

United States
Khondrion BV
Drug Research Unit Ghent, Belgium

Completed

A Dose-escalating Clinical Trial With KH176

Mitochondrial Disease | MELAS | Leigh Syndrome | LHON | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation

Belgium
The University of Texas Health Science Center,...

Recruiting

The International Registry for Leigh Syndrome

Leigh Disease | Leigh Syndrome | Leigh's Necrotizing Encephalopathy | Subacute Necrotizing Encephalomyopathy | Subacute Necrotizing Encephalomyelopathy

United States
PTC Therapeutics

Completed

A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy (MIT-E)

Mitochondrial Diseases | Drug Resistant Epilepsy | Leigh Disease | Leigh Syndrome | Mitochondrial Encephalopathy (MELAS) | Pontocerebellar Hypoplasia Type 6 (PCH6) | Alpers Disease | Alpers Syndrome

United States, Spain, United Kingdom, Canada, France, Italy, Poland, Sweden, Japan

Clinical Trials on Telomere Length

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burundi

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Rare Diseases

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