Clinical Trials on Transthyretin Gene Mutations
Total 1321 results
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Ionis Pharmaceuticals, Inc.CompletedHereditary Transthyretin-Mediated Amyloid PolyneuropathyUnited States, Spain, Taiwan, Italy, Germany, Argentina, Australia, Brazil, Canada, Cyprus, France, Greece, New Zealand, Portugal, Sweden, Turkey
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Novartis PharmaceuticalsActive, not recruitingAdvanced Malignancies That Harbor IDHR132 MutationsBelgium, Germany, Spain, Canada, Australia, United States, Netherlands, Singapore
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Innostellar Biotherapeutics Co.,LtdActive, not recruitingInherited Retinal Dystrophy Associated With RPE65 MutationsChina
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Nalo Therapeutics Inc.RecruitingEGFR Mutation-Related TumorsKorea, Republic of, United States, Taiwan
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingGenetic Predisposition to Disease | Gene Rearrangement | Genome InstabilityItaly
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Brigham and Women's HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)CompletedCircadian Rhythm | Melatonin | Glucose | Genes | LightUnited States
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Puma Biotechnology, Inc.TerminatedSolid Tumors Harboring Somatic HER2 or EGFR Exon 18 MutationsFrance, United States, Spain, Belgium, United Kingdom, Serbia, Australia, Israel, Canada, Denmark, Ireland, Italy, Korea, Republic of
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Taiho Oncology, Inc.RecruitingAdvanced Cholangiocarcinoma | FGFR2 Fusions | Gene RearrangementUnited States, Korea, Republic of, Spain, Japan, Portugal, Italy, China, Argentina, Brazil, Poland, Australia
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BayerRecruitingAdvanced or Recurrent Solid Tumor Harboring an NTRK Gene FusionJapan
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AstraZenecaRecruitingCarpal Tunnel Syndrome | Amyloidosis | Polyneuropathy | Hereditary Transthyretin AmyloidosisRussian Federation
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PfizerCompletedTransthyretin Amyloidosis Cardiomyopathy (ATTR-CM)Italy, Romania, France, Australia, Austria, Portugal, Slovakia, Slovenia, Spain, United Kingdom
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Abramson Cancer Center at Penn MedicineActive, not recruitingAdvanced Breast Cancer | Metastatic Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Locally Advanced Breast CancerUnited States
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Intergroupe Francophone de Cancerologie ThoraciquePfizerCompletedALK Gene Rearrangement Positive | Non-small Cell Lung Cancer Metastatic | ROS-1 Gene Rearrangement PositiveFrance
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Alnylam PharmaceuticalsCompletedPolyneuropathy | Hereditary Transthyretin-mediated (ATTRv) AmyloidosisUnited States
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Northwestern UniversityNorthwestern Memorial Hospital; Saint Joseph Hospital, Chicago, IllinoisRecruitingBreast Cancer | BRCA MutationUnited States
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Xinhua Hospital, Shanghai Jiao Tong University...UnknownGenu Valgum or Varum | Growth; Arrested, Bone | Epiphyseal Arrest, Lower Leg
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Instituto Nacional de Cancerologia de MexicoRecruitingNon-small Cell Lung Cancer | Brain Metastases | EGFR Gene MutationMexico
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Radboud University Medical CenterA-T Children's Project; Twan foundation (https://twanfoundation.nl)CompletedAtaxia Telangiectasia | ATM Gene MutationNetherlands
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Baylor College of MedicineDoris Duke Charitable FoundationRecruitingRAI1 Gene 17P11.2 Deletion+DuplicationUnited States
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Jacobio Pharmaceuticals Co., Ltd.RecruitingSolid Tumors | ER+ Breast Cancer | ARID1A Gene Mutation | Triple Negative Breast Cancer, TNBC | Small Cell Lung Cancer, SCLCUnited States, China
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Memorial Sloan Kettering Cancer CenterAstraZenecaRecruitingNSCLC | Lung Cancer | Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Stage I | PD-L1 Gene Mutation | Non-small Cell Lung Cancer Stage IIIA | Non-small Cell Lung Cancer Stage IIUnited States
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AmgenActive, not recruitingAdvanced/Metastatic Solid Tumors With KRAS p.G12C MutationTaiwan, Hong Kong
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Institut CurieCompletedWomen With BRCA1 Germline Deleterious MutationFrance
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Johns Hopkins UniversityNational Cancer Institute (NCI); National Institutes of Health (NIH); ChiRhoClin...RecruitingLynch Syndrome | Pancreas Cancer | Gene Mutation | Peutz-Jeghers Syndrome (PJS) | Germline Mutation CarrierUnited States
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University of PennsylvaniaAstraZeneca; Ionis Pharmaceuticals, Inc.Active, not recruitingHereditary Amyloidosis, Transthyretin-RelatedUnited States
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Danish Head and Neck Cancer GroupRecruitingHypoxia | Head and Neck Squamous Cell Carcinoma | Radiotherapy | Hypoxic Modification | Gene Profile, Gene SignatureDenmark
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University Health Network, TorontoSuspendedBreast Cancer | Breast Diseases | Genetic Predisposition to Disease | Surgery | Surgery--Complications | BRCA1 Mutation | BRCA2 MutationCanada
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Seoul National University HospitalBayer; Korean Society of Breast Imaging & Korean Society For Breast ScreeningUnknownBreast Cancer | BRCA1 Mutation | BRCA2 Mutation | Recurrent Breast Cancer | Metachronous NeoplasmKorea, Republic of
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University of MichiganCompletedWomen With BRCA 1 or BRCA 2 Mutation | Non-tested Female Family MembersUnited States
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The First Affiliated Hospital of Guangzhou Medical...Unknown
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Hospitales Universitarios Virgen del RocíoCompletedAcute Aortic Syndrome | Gene AbnormalitySpain
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Al-Azhar UniversityCompleted
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Shahid Beheshti University of Medical SciencesCompletedGenu VarumIran, Islamic Republic of
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Universiti Putra MalaysiaCentral Sugars Refinery Sdn Bhd, MalaysiaTerminatedMetabolic Syndrome | Cardiometabolic Risk | Gene ExpressionMalaysia
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Assistance Publique - Hôpitaux de ParisRecruiting
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Kura Oncology, Inc.AvailableAcute Lymphoblastic Leukemia, With Appropriate Mutations | Acute Myeloid Leukemia, With NPM1 Mutations
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Cairo UniversityCompleted
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Diakonessenhuis, UtrechtAgendiaCompletedBreastcancer | Invasive Breast Carcinoma by Gene Expression ProfileNetherlands
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Mayo ClinicAllerganCompletedNeoplasms | Pain, Postoperative | Breast Cancer | Breast Diseases | BRCA1 Mutation | BRCA2 MutationUnited States
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Rennes University HospitalRecruitingTransthyretin Amyloidosis | Amyloidosis, HereditaryFrance
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AstraZenecaNo longer available
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Lei LiRecruitingEpithelial Ovarian Cancer | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation | Drug Resistance | Overall Survival | Progression-free Survival | Poly(ADP-ribose) Polymerase InhibitorChina
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Shaare Zedek Medical CenterRecruitingParkinson Disease | Gaucher Disease | GBA Gene MutationIsrael
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Pacific Parkinson's Research CentreUniversity of British Columbia; Oregon Health and Science University; University... and other collaboratorsRecruitingParkinson Disease | Gaucher Disease | GBA Gene MutationUnited States, Canada
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The First Affiliated Hospital of Soochow UniversityUnknown
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Peloton Therapeutics, Inc., a subsidiary of Merck...Active, not recruitingVHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell CarcinomaUnited States, Denmark, United Kingdom, France
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Institute of Cancer Research, United KingdomCancer Research UK; National Institute for Health Research, United KingdomRecruitingProstate Cancer | BRCA1 Mutation | BRCA2 MutationUnited Kingdom
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European Organisation for Research and Treatment...AstraZenecaWithdrawnBRCA1 Mutation | BRCA2 Mutation | TNBC - Triple-Negative Breast Cancer
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New York Stem Cell Foundation Research InstituteSilverstein FoundationRecruitingHealthy | Parkinson Disease | Gaucher Disease | GBA Gene MutationUnited States
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University of California, DavisNational Cancer Institute (NCI); Merck Sharp & Dohme LLC; NovartisActive, not recruitingKRAS Gene Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Recurrent Non-Squamous Non-Small Cell Lung Carcinoma | Metastatic Non-Squamous Non-Small Cell Lung CarcinomaUnited States