Clinical Trials on Unipolar Major Depression

Total 10464 results

Centro Universitário de Anapolis

Recruiting

Post COVID-19 Pulmonary Rehabilitation Program (COVID19REHAB)

Lung Diseases | Covid19 | Muscle Weakness | Respiratory Insufficiency | COVID-19 Respiratory Infection | Anxiety Disorder; Mixed With Depression (Mild)

Brazil
VA Office of Research and Development

Completed

Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop (STEP-Home)

Depression | Pain | Anxiety Disorders | Suicide | Traumatic Brain Injury | Substance Related Disorders | Post-traumatic Stress Disorder

United States
Columbia University
National Institute of Mental Health (NIMH); Yale University

Active, not recruiting

Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings

Depression, Anxiety | Human Immunodeficiency Virus | Risk Reduction | Alcohol Abuse | Behavior, Sex

Romania
D'Or Institute for Research and Education
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Active, not recruiting

Mental Health of Professionals Working in Pediatric Intensive Care Units During the COVID-19 Pandemic

Depression | Covid19 | Burnout, Professional | Stress Disorders, Post-Traumatic | Compassion Fatigue | Anxiety

Brazil
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1008: Exercise, Diet, & Counseling in Improving Weight Loss in Overweight Female Breast or Colorectal Cancer Survivors

Depression | Pain | Breast Cancer | Fatigue | Colorectal Cancer | Cognitive/Functional Effects | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment | Weight Changes

United States
University of Missouri-Columbia

Recruiting

Baker Gordon Syndrome Natural History Study (BAGOS)

Epilepsy, Generalized | Sleep Disorder | Rare Diseases | Development Delay | Motor Delay | Autism or Autistic Traits | SYT-SSX Fusion Protein Expression

United States
The Center for Mind-Body Medicine
U.S. Army Medical Research and Development Command; Southeast Louisiana Veterans...

Completed

Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations

Anger | Depressive Disorder | Brain Injuries | Anxiety Disorders | Stress Disorders, Post Traumatic

United States
Centre Hospitalier de Valence

Not yet recruiting

Evaluation of the Medical Service by Socio-aesthetics in Oncology (RCT-SE)

Anxiety Depression | Cancer, Breast | Cancer Pain | Cancer of Colon | Cancer, Lung | Cancer Prostate
University of Texas at Austin
Way West Wellness; SunFlora.Inc

Suspended

CBD Oil for Reducing Emotional Impact of COVID-19 (CBDOIL)

Anger | Sleep Disturbance | Anxiety Depression | Substance Abuse | Alcohol Abuse | Stress Reaction

United States
Charite University, Berlin, Germany

Completed

Evaluation of an Integrated Care Project (ediva)

Depression | Migraine | Asthma | Allergic Rhinitis | Headache | Atopic Eczema

Germany
Brigham and Women's Hospital
CVS Caremark

Completed

Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices (REMIND)

Depression | Epilepsy | Cardiovascular Disease | Diabetes | Breast Cancer | Parkinson's Disease | Mental Health Disorder | Prostatic Hypertrophy, Benign

United States
Federal University of Minas Gerais
Harvard Medical School (HMS and HSDM)

Active, not recruiting

Assessment of Sleep Quality and Mental Health After Using Meditation

Depressive Disorder | Quality of Life | Sleep Disorder | Anxiety Disorders | Insomnia | Spirituality | Stress Disorder | Insomnia Chronic | Insomnia Disorder | Complementary Therapy

Brazil
Peking University Cancer Hospital & Institute

Completed

Gene Expression Profiling of Breast Cancer Cells Predict the Response of Malignant Pleural Effusion (GMPE)

Breast Neoplasms | Neoplasm Metastasis | Immunotherapy | Gene Expression Profiling

China
Johns Hopkins University
Department of Defense Congressionally Directed Medical Research Program

Recruiting

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Depression | Insomnia | Sleep | Traumatic Brain Injury | Memory Impairment | Head Injury | Cognitive Behavioral Therapy | Concussion, Brain | Post-traumatic Stress | Brain Injury Traumatic Mild

United States
Lisa Gallagher
The Cleveland Clinic; National Endowment for the Arts, United States; Cuyahoga...

Terminated

Arts & Health Education to Improve Health, Resilience, and Well-Being

Depression | Heart Diseases | Stroke | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Chronic Pain | Asthma | Anxiety | COPD | CHF | High Cholesterol

United States
University of New Hampshire
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of South... and other collaborators

Completed

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

Depression | Alcohol Drinking | Alcohol; Harmful Use | Social Skills | Coping Behavior | Post-traumatic Stress Disorder | Coping Skills | Social Behavior | Alcohol Abuse | Drinking, College | Social Stigma | Empathy | Self-Criticism | Social Norms | Social Responsibility

United States
The University of Texas Health Science Center at...
South Texas Veterans Health Care System

Completed

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

Depression | Chronic Pain | Traumatic Brain Injury | Opioid Use Disorder | Posttraumatic Stress Disorder

United States
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Terminated

Meditation-Based Breathing Training in Improving Target Motion Management and Reducing Distress in Patients With Abdominal or Lung Cancer Undergoing Radiation Therapy

Depression | Pain | Anxiety | Digestive System Neoplasm | Post-Traumatic Stress Disorder | Lung Neoplasm | Psychological Impact of Cancer

United States
Regina Elena Cancer Institute
University of California, San Diego; Lega Italiana per la Lotta contro i Tumori

Recruiting

New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer

PREDICTIVE BIOMARKERS | Evaluation of HPV-specific E5 Transcript Expression in a Cohort of Patients With HPV-associated OPC | HPV 16 Positive Oropharyngeal Tumors (OPC)

Italy
Universite de Moncton
Movember Foundation; New Brunswick Health Research Foundation

Unknown

Comorbid Mental Disease and Heart Disease in Men (MindTheHeart)

Depressive Disorder | Anxiety Disorders | Stress Disorders, Post-Traumatic | Acute Coronary Syndrome
National Center for Complementary and Integrative...

Completed

Women's Use of Alternative Medicine: A Multiethnic Study

Depression | Arthritis | Urinary Tract Infection | Osteoporosis | Heart Disease | Uterine Fibroids | High Blood Pressure | Headaches
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss

Anxiety | Sleep Disturbance | Malignant Female Reproductive System Neoplasm | Postoperative Pain, Acute | Postoperative Depression

United States
Stanford University
California Breast Cancer Research Program

Completed

Phase I: At-Home Support for Rural Women Using Group Video Calling

Depression | Post-traumatic Stress Disorder | Stage IV Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer

United States
Pace University
Emory University

Not yet recruiting

Music After Stroke To Enhance Rehabilitation (MASTER)

Depressive Disorder | Stroke, Acute | Movement, Abnormal | Expressive Aphasia
INTRuST, Post-Traumatic Stress Disorder - Traumatic...
Medical University of South Carolina; University of California, San Diego; U.S... and other collaborators

Unknown

Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation

Traumatic Brain Injury | Posttraumatic Stress Disorder | Depressive Episode

United States
National Cancer Institute (NCI)

Completed

Psychosocial Correlates and Coping Strategies Associated With Long-Term Survival of HIV-Infected Children

Depressive Disorder | HIV Infections | Acquired Immunodeficiency Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Lance Armstrong Foundation

Active, not recruiting

Depression Treatment and Screening in Ovarian Cancer Patients

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
Washington University School of Medicine
Patient-Centered Outcomes Research Institute; University of Pennsylvania; University... and other collaborators

Active, not recruiting

THRIVE Feasibility Trial (THRIVE)

Depression | Quality of Life | Pain, Postoperative | Surgery | Anesthesia Morbidity | Surgery--Complications | Anesthesia | Nausea, Postoperative | Sleep Disorders, Circadian Rhythm | Anesthesia Awareness | Anesthesia Complication | Anesthesia Emergence Delirium

United States
Dalin Tzu Chi General Hospital

Completed

Vegetarian Diet and Chronic Degenerative Diseases

Depression | Cardiovascular Diseases | Stroke | Dementia | Cataract | Urinary Tract Infections | Gout | Gallstone

Taiwan
Instituto de Investigación Sanitaria Aragón

Recruiting

Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) in People With Post Covid-19 Condition.

Depressive Disorder | Anxiety Disorders | Emotional Disorder | Post COVID-19 Condition

Spain
Brigham and Women's Hospital

Recruiting

Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development

Preterm Birth | Neurodevelopmental Disorders | Breast Milk Expression | Nutrition Disorder, Infant | Brain Development Abnormality

United States
McMaster University
Canadian Institutes of Health Research (CIHR)

Recruiting

Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1 (RIPPLE-C)

Diabetes Mellitus | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Dementia | Congestive Heart Failure | Depression, Anxiety

Canada
Anglia Ruskin University
University of Melbourne; Alzheimer's Society; Norwegian Academy of Music; Cambridgeshire... and other collaborators

Completed

Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia (HOMESIDE)

Depression | Quality of Life | Dementia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Alzheimers | Behavioural and Psychiatric Symptoms of Dementia

United Kingdom, Australia, Germany, Norway, Poland
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation

Depression | Pain | Lymphoma | Myelodysplastic Syndromes | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Anxiety Disorder

United States
Centro Hospitalar Universitario do Algarve
Universidade do Porto; Universidade do Algarve

Recruiting

Neuropsychological Sequelae and Long COVID-19 Fatigue (PostCoV2Psy)

COVID-19 | Mental Fatigue | Post Traumatic Stress Disorder | Anxiety Depression | Fatigue Syndrome, Chronic

Portugal
University Hospital Southampton NHS Foundation...
Portsmouth Hospitals NHS Trust; University of Derby

Recruiting

Severe Asthma, MepolizumaB and Affect: SAMBA Study (SAMBA)

Depression | Anxiety | Emotional Disorder | Psychological Distress | Emotions | Coping Behavior | Emotional Distress | Psychological Adjustment | Psychological Stress | Psychological | Psychosocial Problem | Psychological Disorder | Emotional Dysfunction | Severe Eosinophilic Asthma | Psychosocial Stressor | Adjustment | Adjustment...

United Kingdom
Shanghai Mental Health Center

Recruiting

The China Longitudinal Aging Study of Cognitive Impairment

Depression | Anxiety | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia With Lewy Bodies | Dementia Frontal

China
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Pain | Brain Injuries | Chronic Disease | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder | Wounds and Injury

United States
Chinese University of Hong Kong

Recruiting

Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE) (LANDSCAPE)

Parkinson Disease | Aging | Dementia Alzheimers | Depression in Old Age | Dementia Frontotemporal

Hong Kong
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
University of North Carolina, Greensboro

Completed

Rhythmically Entrained Exercise in Community-Dwelling Older Adults (REECO)

Depression | Cognitive Impairment | Cognitive Dysfunction | Dementia | Alzheimer Disease | Exercise | Caregiver Burden | Healthy Aging | Fall | Mild Cognitive Impairment | Elderly | Executive Function | Gait | Mental Health | Cognitive Decline | Memory Disorders | Memory Impairment | Walking | Cognition | Physical Exertion | Music Therapy and other conditions

United States
Copenhagen University Hospital at Herlev

Unknown

Drug-induced Repolarization ECG Changes

Depression | Pathologic Processes | Heart Diseases | Cardiovascular Diseases | Congenital Abnormalities | Death | Death, Sudden | Arrhythmias, Cardiac | ADHD | Heart Arrest | Heart Defects, Congenital | Cardiovascular Abnormalities | Genetic Disease | Death, Sudden, Cardiac | Psychiatric Disorder | Genetic Syndrome | Long... and other conditions

Denmark
Centre de Recherche de l'Institut Universitaire...

Unknown

Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers

Depressive Disorder | Anxiety Disorders | Stress Disorders, Post-Traumatic | Substance Abuse | Absenteeism | Acute Stress Disorder

Canada
University of Southern Denmark
Zealand University Hospital; Holbaek Sygehus; Naestved Hospital; Nykøbing Falster... and other collaborators

Active, not recruiting

Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity (MOBILIZE)

Depression | Heart Failure | Hypertension | Chronic Obstructive Pulmonary Disease | Osteoarthritis, Knee | Coronary Heart Disease | Osteoarthritis, Hip | Type2 Diabetes

Denmark
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Faculty of Medicine, Tarumanagara University
Hana Old Age Home

Unknown

Determinants of Cognitive Impairment Among Geriatrics

Depression | Hypertension | Obesity | Diabetes | Osteoarthritis | Cognitive Impairment | Dyslipidemias | Dementia | Mobility Limitation | Hearing Impairment | Vision Impairment and Blindness | Central Obesity

Indonesia
National Cancer Institute (NCI)

Completed

Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer (ADCC)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell... and other conditions

United States
Freeman-Sheldon Research Group, Inc.

Terminated

Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions (FSS-QLS)

Depressive Disorder | Craniofacial Abnormalities | Posttraumatic Stress Disorder | Arthrogryposis

United States, Guatemala
St. Olavs Hospital
Norwegian University of Science and Technology; The Research Council of Norway and other collaborators

Recruiting

Early Psychological Intervention After Rape (EIR)

Sexual Dysfunctions, Psychological | Sleep Disturbance | Post Traumatic Stress Disorder | Depression, Anxiety | Activity, Motor | Pelvic Pain Syndrome | Rape Sexual Assault | Pelvic Floor Myalgia | Cortisol Deficiency

Norway

Clinical Trials on Unipolar Major Depression

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Germany

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations