Clinical Trials on Unresectable Malignant Neoplasm in Canada

Total 7489 results

National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer

Hematopoietic and Lymphoid Cell Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Liver | Unresectable Solid Neoplasm

United States, Canada
Lawson Health Research Institute
London Health Sciences Centre

Completed

Can Electronic Information Kiosks Enhance Patient Accrual for Cancer Clinical Trials? A Pilot and Feasibility Study

Malignant Neoplasm

Canada
Sunnybrook Health Sciences Centre
Genomic Health®, Inc.

Completed

The Impact of the Oncotype DX® Breast Cancer Assay on Treatment Decisions in a Canadian Population

Hormone Receptor Positive Malignant Neoplasm of Breast

Canada
McMaster University

Active, not recruiting

A Trial Comparing Surgeon-administered TAP Block With Placebo After Midline Laparotomy in Gynecologic Oncology

Surgical Procedure, Unspecified | Genital Neoplasm Malignant Female

Canada
University Health Network, Toronto

Active, not recruiting

FAZA PET/MRI Pancreas

Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Cancer | Pancreatic Adenocarcinoma Non-resectable

Canada
MedImmune LLC

Active, not recruiting

Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma (Tremelimumab)

Unresectable Pleural or Peritoneal Malignant Mesothelioma

United States, Italy, Spain, United Kingdom, Belgium, Canada, Poland, France, Korea, Republic of, Hungary, Russian Federation, Germany, Australia, South Africa, Netherlands, Romania, Sweden, Israel, Denmark
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

First in Human Study of M1069 in Advanced Solid Tumors

Metastatic or Locally Advanced Unresectable Solid Tumors

United States, Canada
University Health Network, Toronto
Canadian Association of Radiation Oncology

Completed

Healthy Bones Study

Locally Advanced Malignant Neoplasm

Canada
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)

Metastatic or Locally Advanced Unresectable Solid Tumors

United States, Canada, Spain
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma

Intraocular Melanoma | Recurrent Melanoma | Stage IV Melanoma | Ciliary Body and Choroid Melanoma, Medium/Large Size | Ciliary Body and Choroid Melanoma, Small Size | Iris Melanoma | Extraocular Extension Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Superficial... and other conditions

Canada
Sanofi

Active, not recruiting

Evaluation of SAR408701 in Patients With Advanced Solid Tumors

Neoplasm Malignant

United States, Canada, France, Korea, Republic of, Spain
John Lenehan

Not yet recruiting

CHemotherapy And Stool Transplant in PDAC (CHASe-PDAC) (CHASe-PDAC)

Unresectable or Metastatic Advanced Pancreatic Ductal Adenocarcinoma

Canada
Galera Therapeutics, Inc.

Terminated

Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer

Unresectable Pancreatic Cancer | Borderline Resectable Pancreatic Cancer | SBRT

United States, France, United Kingdom, Canada
Jewish General Hospital

Unknown

Phase I/II Study of Ribavirin Given as Monotherapy in Solid Tumour Cancer Patients

Malignant Solid Tumour

Canada
National Cancer Institute (NCI)

Completed

Sunitinib in Treating Patients With Advanced Malignant Pleural Mesothelioma

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma

Canada
Isabel Blancas

Completed

Retrospective Study Assessment Treatment Response Faslodex®( 500 mg) (EFFICACY)

Malignant Neoplasm of Breast Stage IV

Spain
Sanofi

Completed

Safety and Efficacy of Cabazitaxel in Pediatric Patients With Refractory Solid Tumors Including Central Nervous System Tumors

Malignant Solid Tumor - Malignant Nervous System Neoplasm

United States, Canada
University Health Network, Toronto

Completed

A Quality of Life Study re Management of Malignant Pleural Effusions

Malignant Pleural Effusions

Canada
Ottawa Hospital Research Institute

Unknown

Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population (OPUS)

Malignant Pleural Effusion

Canada
Lawson Health Research Institute

Unknown

Feasibility Study Comparing Enteral vs Parenteral Nutritional Outcomes in Autologous Stem Cell Transplant Patients

Malignant Hematologic Neoplasm

Canada
Sanofi

Completed

A Phase I/Ib Trial for the Evaluation of SAR260301 in Monotherapy or in Combination With Vemurafenib in Patients With Various Advanced Cancer

Neoplasm Malignant

Canada, United States
London Health Sciences Centre
University of Western Ontario, Canada; London Regional Cancer Program, Canada

Terminated

Imaging Study of Glioblastomas Treated With Avastin

Malignant Gliomas

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
McMaster University
McMaster Surgical Associates

Terminated

The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection

Pleural Effusion | Pleural Effusion Malignant

Canada
University Health Network, Toronto

Active, not recruiting

Short Neoadjuvant Hemithoracic IMRT for MPM

Malignant Pleural Mesothelioma

Canada
University Health Network, Toronto

Recruiting

Femoral Bone Metastases

Cancer | Metastatic Malignant Neoplasm to Femur | Risk of Fracture

Canada
Stephen Couban
Genzyme, a Sanofi Company

Completed

Healthy Donor Study II - Comparing Plerixafor With G-CSF and Plerixafor

Malignant Lymphoma, Stem Cell Type

Canada
Alberta Health Services, Calgary
University of Calgary; Tom Baker Cancer Centre

Not yet recruiting

Prophylactic LYMphatic Reconstruction (LYMbR) to Prevent Lymphedema After Node Dissection for Cutaneous Malignancies (LYMbR)

Lymphedema of Limb | Malignant Skin Neoplasm

Canada
C17 Council

Completed

Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients With Relapsed Solid Tumors

Relapsed Malignant Solid Tumor

Canada
Ontario Clinical Oncology Group (OCOG)
Novartis Pharmaceuticals

Terminated

A Phase II Study of Single-agent DOVitinib in Advanced Malignant PlEural Mesothelioma Which Has Progressed Following Prior Platinum-Antifolate Chemotherapy (DOVE-M)

Advanced Malignant Pleural Mesothelioma | MPM

Canada
AHS Cancer Control Alberta
Celgene

Active, not recruiting

A Study to See the Effects That a New Combination of the Three Drugs, Nab-paclitaxel, Gemcitabine, and Cisplatin Has on Biliary Tract Cancer (AX-CSARC)

Unresectable Biliary Tract Cancer

Canada
Lawson Health Research Institute

Recruiting

Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer (Pre-PLaN)

Non-small Cell Lung Cancer Stage IB (Resectable) | Non-small Cell Lung Cancer Stage II (Resectable) | Non-small Cell Lung Cancer Stage ⅢA (Resectable)

Canada
Ottawa Hospital Research Institute

Unknown

Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE Patients

Malignant Pleural Effusion

Canada
University of Saskatchewan

Completed

Power Injectable Versus a Non-Power Injectable, Upper Arm, TIVAD for Chemotherapy

Malignancy

Canada
McGill University Health Centre/Research Institute...

Unknown

The Effect of Epidural Fentanyl on Immune Function

Malignancy

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors

Childhood Malignant Neoplasm

United States, Canada, Australia, Puerto Rico, Switzerland
University of Alberta
Capital Health, Canada

Completed

The Safety and Efficacy of DCA for the Treatment of Brain Cancer

Malignant Gliomas, Glioblastoma Multiforme

Canada
Hamilton Health Sciences Corporation
Ontario Clinical Oncology Group (OCOG); Juravinski Cancer Centre Foundation

Unknown

Robotic Compared to Fixed Gantry Radiosurgery for Brain Metastases (TRICK)

Metastatic Malignant Neoplasm to the Adult Brain

Canada
Bristol-Myers Squibb

Terminated

A Dose Escalation and Combination Immunotherapy Study to Evaluate BMS-986226 Alone or in Combination With Nivolumab or Ipilimumab in Patients With Advanced Solid Tumors

Cancer | Neoplasm | Tumors | Malignancy

United States, Canada, Spain, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Neuropsychological and Behavioral Testing in Younger Patients With Cancer

Childhood Malignant Neoplasm

United States, Canada, Puerto Rico, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Vincristine Pharmacokinetics in Infants

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States, Australia, Canada
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Role of Cyberknife Stereotactic Radiation Therapy (SBRT) Followed by Gemcitabine for Patients With Locally Advanced Pancreatic Cancer

Pancreatic Cancer | Unresectable Pancreatic Cancer

Canada
Formation Biologics

Unknown

A Trial of AVID200, a Transforming Growth Factor β (TGFβ) Inhibitor, in Patients Malignancies

Malignant Solid Tumor

United States, Canada
British Columbia Cancer Agency
BC Cancer Foundation; Pancreatic Cancer Canada

Unknown

The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma (Metformin 001)

Resectable Pancreatic Ductal Adenocarcinoma

Canada
AO Foundation, AO Spine
Orthopaedic Research Foundation

Completed

The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO) (EPOSO)

Secondary Malignant Neoplasm of Vertebral Column

United States, Canada, Hungary
AstraZeneca

Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma (eVOLVE-Meso)

Unresectable Pleural Mesothelioma

Denmark, Italy, Australia, Korea, Republic of, Belgium, Poland, United States, Canada, Japan, United Kingdom, Spain, China, France, Taiwan, Norway, Brazil, Germany, Switzerland, South Africa, Turkey, Netherlands
Children's Oncology Group
National Cancer Institute (NCI); MedStar Georgetown University Hospital

Active, not recruiting

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States, Canada
University Health Network, Toronto

Completed

Study of Ipilimumab in the Immune System

Previously Untreated and Histologically Confirmed Stage III (Unresectable) or Stage IV Melanoma

Canada

Clinical Trials on Unresectable Malignant Neoplasm in Canada

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