Clinical Trials on Unresectable Malignant Neoplasm

Total 107913 results

Novartis Pharmaceuticals

Completed

A Study of the Efficacy and Safety of Imatinib Mesylate in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing C-kit Gene

Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumor (GIST)

United States, Finland, Australia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Sapanisertib, Carboplatin, and Paclitaxel in Treating Patients With Recurrent or Refractory Malignant Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer

Malignant Neoplasm | Metastatic Malignant Neoplasm to the Bone

United States
Hospital Universitari de Bellvitge
Hospital Universitario Ramon y Cajal; Complejo Hospitalario de Navarra; University... and other collaborators

Not yet recruiting

EUS-guided Choledochoduodenostomy vs ERCP as First Line in Malignant Distal Obstruction in Resectable Disease (CARPEDIEM-1 Trial)

Biliary Tract Neoplasms | Pancreatic Cancer Resectable | Malignant Biliary Obstruction

Spain
FutureGen Biopharmaceutical (Beijing) Co., Ltd

Recruiting

Safety, Tolerability and Pharmacokinetic Profile of M108 Monoclonal Antibody in Patients With Advanced Unresectable Solid Tumors in China

Advanced Unresectable Solid Tumors

China
Andes Biotechnologies

Terminated

Phase 1 Safety and Tolerability Study of Andes-1537 for Injection in Patients With Advanced Unresectable Solid Tumors

Advanced Unresectable Solid Tumors

United States
University of Washington
GlaxoSmithKline

Recruiting

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic... and other conditions

United States
AstraZeneca

Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma (eVOLVE-Meso)

Unresectable Pleural Mesothelioma

Denmark, Italy, Australia, Korea, Republic of, Belgium, Poland, United States, Canada, Japan, United Kingdom, Spain, China, France, Taiwan, Norway, Brazil, Germany, Switzerland, South Africa, Turkey, Netherlands
University of Southern California
National Cancer Institute (NCI)

Recruiting

Norris ORIEN Total Cancer Care

Malignant Neoplasm | Cancer Risk

United States
Chiang Mai University

Unknown

Adapted ERAS in Gynecologic Oncology Surgery

Genital Neoplasm Malignant Female

Thailand
Florin Iordache

Completed

Peritoneal Bacterial Contamination Following Resection With Closed or Open Rectal Stump for Left-sided Cancer

Bacterium-Related Malignant Neoplasm
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Unresectable Gastric Adenocarcinoma | Unresectable Gastroesophageal Junction Adenocarcinoma | Metastatic Gastric Cancer | Unresectable Esophageal Cancer | Metastatic Esophageal Carcinoma | Metastatic Gastric... and other conditions

United States
Sonavex, Inc.

Recruiting

Observational Study of Outcomes After EchoMark and EchoSure-based Free Flap Monitoring

Malignant Neoplasm | Free Flap Transfer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

RCT of QPS vs General Information Sheet

Caregiver | Advanced Malignant Neoplasm | Physician

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses (CREDIT)

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

EHealth Mindful Movement and Breathing in Improving Outcomes in Participants Undergoing Gynecologic Surgery

Ovarian Carcinoma | Malignant Uterine Neoplasm | Malignant Female Reproductive System Neoplasm | Ovarian Neoplasm | Uterine Neoplasm | Female Reproductive System Neoplasm | Suspicious for Malignancy

United States
Methodist Health System

Recruiting

Evaluation of Outcomes From Treatment of Benign or Malignant Gastroesophageal Diseases

Pancreatic Malignant Neoplasm Primary

United States
University of Southern California
National Cancer Institute (NCI)

Completed

Perceptions of Side Effects of Cancer Chemoradiotherapy

Malignant Neoplasm | Side Effect

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Take the Fight in Supporting and Empowering Patients With Cancer

Malignant Neoplasm | Healthy Subject

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Withdrawn

JeffQuit Group Therapy Program for Smoking Cessation in Patients With a History of Cancer

Current Smoker | Malignant Neoplasm

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis

Pain | Metastatic Malignant Neoplasm in the Bone | Malignant Neoplasm

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Hereditary Malignant Neoplasm

United States
Hospital Universitari de Bellvitge
Hospital Universitario Ramon y Cajal; Complejo Hospitalario de Navarra; University... and other collaborators

Not yet recruiting

EUS-Gallbladder vs CDS as First Line in MBDO- Palliative (CARPEGIEM Trial) (CARPEGIEM)

Biliary Tract Neoplasms | Malignant Biliary Obstruction | Pancreatic Cancer Non-resectable

Spain
Sanofi

Completed

Safety and Efficacy of Cabazitaxel in Pediatric Patients With Refractory Solid Tumors Including Central Nervous System Tumors

Malignant Solid Tumor - Malignant Nervous System Neoplasm

United States, Canada
Sidney Kimmel Comprehensive Cancer Center at Johns...
Johns Hopkins University; Axogen Corporation

Completed

Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy

Cancer | Neuropathy | Malignant Neoplasm | Chemotherapy-induced Peripheral Neuropathy | Malignancy | Neuropathies Sensory

United States
National Cancer Institute (NCI)

Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Metastatic Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Unresectable Sarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

Malignant Solid Neoplasm | Breast Carcinoma | Digestive System Neoplasm | Skin Carcinoma | Malignant Female Reproductive System Neoplasm | Metastatic Malignant Neoplasm of Unknown Primary | Malignant Head and Neck Neoplasm | Malignant Brain Neoplasm | Malignant Central Nervous System Neoplasm | Malignant... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients With Primary or Metastatic Brain Tumors

Metastatic Malignant Neoplasm in the Brain | Malignant Brain Neoplasm | Recurrent Malignant Brain Neoplasm

United States
Memorial Sloan Kettering Cancer Center

Completed

A Study of Pembrolizumab and Cryoablation in People With Mesothelioma

Lung Cancer | Unresectable Mesothelioma

United States
National Cancer Institute (NCI)

Terminated

Trastuzumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer or Bile Duct Cancer That Cannot Be Removed by Surgery

Malignant Neoplasm | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adenocarcinoma of the Gallbladder | Adenocarcinoma of the Extrahepatic Bile Duct

United States
National Cancer Institute, Thailand

Completed

Discordant Hormonal Status of Breast Cancer.

Malignant Neoplasm of Breast.

Thailand
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
University of California, San Francisco

Withdrawn

Ride to Care - Quality of Life With Transportation for RT

Metastatic Malignant Neoplasm | Locally Advanced Malignant Neoplasm
University of California, San Francisco
Lazarex Cancer Foundation

Terminated

Impact of Phone Call About Financial Reimbursement Program on Access to Cancer Clinical Trials

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Neoplasm

United States
Mayo Clinic

Recruiting

Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Mayo Clinic

Recruiting

Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Mayo Clinic

Not yet recruiting

Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluation of an Education Program to Increase Knowledge and Participation in Clinical Trials Among Racial/Ethnic and Rural Populations

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Evaluation of a Couple-Based Physical Activity Intervention

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Mayo Clinic

Recruiting

Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Evaluating Clinical Evaluation Tools for Predicting Risk of Complications After Hematopoietic Stem Cell Transplant

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
University of Rochester NCORP Research Base
National Cancer Institute (NCI); Roswell Park Cancer Institute

Recruiting

An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study (DiRECT)

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Roswell Park Cancer Institute

Recruiting

Yoga Intervention for the Improvement of Cancer-Related Stress in Cancer Survivors

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center

Active, not recruiting

Survey Assessment of Patient and Provider Impressions of Telemedicine in Radiation Oncology

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Mayo Clinic

Enrolling by invitation

Qualitative Techniques to Define Meaningful Within-Patient Change in Symptoms of Advanced Cancer Patients

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Enrolling by invitation

Testing Counseling and Mobile Health Interventions to Improve Physical Activity and Diet Quality in Survivors of Childhood Cancer (SALSA)

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States

Clinical Trials on Unresectable Malignant Neoplasm

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Indonesia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations