Clinical Trials on Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Total 4871 results

City of Hope Medical Center

Recruiting

Pancreatic Cancer Detection Consortium (PCDC)

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Resectable | Pancreatic Carcinoma | Pancreatic Cancer Non-resectable | Pancreatic Cancer Stage III | Pancreatic Cancer Stage | Pancreatic Cancer Stage II | Pancreatic Cancer, Adult | Pancreatic... and other conditions

Korea, Republic of, United States, Japan
Washington University School of Medicine

Terminated

Whipple Procedure: Standard of Care vs. Thunderbeat

Pancreatic Neoplasms | Bile Duct Carcinoma

United States
Ludwig-Maximilians - University of Munich
Roche Pharma AG

Unknown

Gemcitabine Plus Erlotinib in RASH-positive Patients With Metastatic Pancreatic Cancer (ML22774)

Metastatic Pancreatic Adenocarcinoma

Germany
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Resectable Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Ductal Adenocarcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma

United States, Israel, Canada
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Surgery and Thermal Hepatic Ablation Combined With Chemotherapy in Hepatic Oligometastatic Pancreatic Cancer (HOPE-1)

Pancreatic Ductal Adenocarcinoma
Oryx GmbH & Co. KG

Completed

Parvovirus H-1 (ParvOryx) in Patients With Metastatic Inoperable Pancreatic Cancer (ParvOryx02)

Carcinoma, Pancreatic Ductal

Germany
Zhejiang Cancer Hospital

Recruiting

Surufatinib Plus Cadonilimab in Patients With Unresectable or Metastatic Bile Duct Adenocarcinoma

Bile Duct Adenocarcinoma

China
IRCCS San Raffaele
Università Vita-Salute San Raffaele

Recruiting

Advanced Therapies for Liver Metastases (LiMeT)

Liver Metastasis | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

Italy
The Affiliated Hospital of Qingdao University

Recruiting

Prognostic Value of Myosteatosis and Creatinine-to-cystatin C Ratio in Patients With Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma | Myosteatosis | Skeletal Muscle Radiodensity | Scr/CysC Ratio

China
Zhejiang Cancer Hospital

Recruiting

Disitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct Adenocarcinoma

HER2 Gene Mutation | Bile Duct Adenocarcinoma Non-Resectable

China
National Cancer Center, Korea
Seoul National University Hospital

Not yet recruiting

Tripegfilgrastim Trial to Reduce the Risk of Severe Neutropenia in Patients With Unresectable Pancreaticobiliary Cancers (Dulastin)

Unresectable Pancreatic Cancer | Unresectable Biliary Tract Carcinoma | Unresectable Bile Duct Carcinoma
Patrick Joseph Loehrer Sr.
Indiana University; Taiho Oncology, Inc.

Terminated

Study of Lonsurf in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced (PDAC)

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States
First People's Hospital of Hangzhou

Completed

EUS-RFA for Unresectable Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

China
Academisch Medisch Centrum - Universiteit van Amsterdam...
Comprehensive Cancer Centre The Netherlands; Dutch Cancer Society

Completed

Impact of Nationwide Enhanced Implementation of Best Practices in Pancreatic Cancer Care (PACAP-1) (PACAP-1)

Carcinoma, Pancreatic Ductal

Netherlands
Rambam Health Care Campus

Unknown

Correlation of Serum CA19-9 Levels With Levels in Saliva and Urine of Patients With Ductal Adenocarcinoma of the Pancreas

Carcinoma, Pancreatic Ductal

Israel
Northwestern University
National Cancer Institute (NCI)

Recruiting

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer... and other conditions

United States
Memorial Sloan Kettering Cancer Center
Halozyme Therapeutics; Miami Cancer Institute

Active, not recruiting

Study Of Gemcitabine, Nab-paclitaxel, PEGPH20 and Rivaroxaban for Advanced Pancreatic Adenocarcinoma

Pancreatic Cancer | Advanced Pancreatic Ductal Adenocarcinoma

United States
University of Rochester
Bristol-Myers Squibb; Syntrix Biosystems, Inc.

Recruiting

A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States
Silenseed Ltd

Recruiting

A Phase 2 Study of siG12D LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer (PROTACT)

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States, Israel
Pancreatic Cancer Research Team
Merck Sharp & Dohme LLC; University of Washington; Halozyme Therapeutics

Unknown

Second-line Study of PEGPH20 and Pembro for HA High Metastatic PDAC

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States
Brian Anderson, MD

Recruiting

Ketamine-assisted Therapy for Patients With Pancreatic Ductal Adenocarcinoma

Pain, Acute | Pancreatic Ductal Adenocarcinoma

United States
Orion Biotechnology Polska Sp. z o.o.

Not yet recruiting

Study of OB-002 in Patients With Refractory Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Cancer | Metastatic Breast Cancer | Metastatic Urothelial Carcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer
Singapore General Hospital

Unknown

Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Pancreatic Neuroendocrine Tumor

Singapore
Memorial Sloan Kettering Cancer Center

Recruiting

Imaging Study of 18F-FAC PET Scans to Assess Standard Treatment in People With Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States
Silenseed Ltd

Completed

Phase I - Escalating Dose Study of siG12D LODER (Local Drug EluteR) in Patients With Locally Advanced Adenocarcinoma of the Pancreas, and a Single Dose Study of siG12D LODER (Local Drug EluteR) in Patients With Non-operable Adenocarcinoma of the Pancreas

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

Israel
Massachusetts General Hospital
American Society for Gastrointestinal Endoscopy

Withdrawn

Pancreatic Stent to Prevent Leak After Distal Pancreatectomy (LEAPS)

Pancreatic Cancer | Pancreatic Diseases | Pancreatic Cyst | Pancreatic Surgery | Pancreatic Duct Stenting | Distal Pancreatectomy | Pancreatic Ducts

United States
University Health Network, Toronto

Active, not recruiting

Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection (COMPASS)

Carcinoma, Pancreatic Ductal

Canada
Sumitomo Pharma America, Inc.

Completed

A Study of Napabucasin Plus Nab-Paclitaxel With Gemcitabine in Adult Patients With Metastatic Pancreatic Adenocarcinoma (CanStem111P)

Carcinoma, Pancreatic Ductal

United States, France, Netherlands, Spain, Taiwan, China, Belgium, Korea, Republic of, Austria, Singapore, Japan, Italy, Germany, Portugal, Poland, Czechia, Australia, Canada, Russian Federation, Ukraine
St. Olavs Hospital
Norwegian University of Science and Technology

Completed

Ultrasound-enhanced Uptake of Chemotherapy in Patients With Inoperable Pancreatic Ductal Adenocarcinoma (PDAC)

Carcinoma, Pancreatic Ductal

Norway
West China Hospital
Royal Liverpool University Hospital

Unknown

Standard Versus Extended Lymphadenectomy in Pancreatoduodenectomy for Patients With Pancreatic Head Adenocarcinoma

Carcinoma, Pancreatic Ductal

China
Silence Therapeutics GmbH
FGK Clinical Research GmbH; Granzer Regulatory Consulting & Services

Completed

Atu027 Plus Gemcitabine in Advanced or Metastatic Pancreatic Cancer (Atu027-I-02) (Atu027-I-02)

Carcinoma, Pancreatic Ductal

Germany
Changhai Hospital
ImmunoGene Biotechology Co.,Ltd

Unknown

Safety and Efficacy Evaluation of iAPA-DC/CTL Combined Gemcitabine Therapy on Advanced Pancreatic Cancer

Carcinoma, Pancreatic Ductal

China
Peking Union Medical College Hospital
Tongji Hospital; Beijing Hospital; The First Affiliated Hospital of Xiamen University

Not yet recruiting

A Cohort Study on Screening and Follow-up of High-risk Population of PDAC Based on EUS

Carcinoma, Pancreatic Ductal
BUSQUETS, JULI

Not yet recruiting

Predictive Factors for Resection and Survival in Type A Borderline Resectable Pancreatic Ductal Adenocarcinoma Patients After Neoadjuvant Therapy (PF-BARNA)

Carcinoma, Pancreatic Ductal
Wuhan Union Hospital, China

Not yet recruiting

Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Cancer Non-resectable | Pancreatic Ductal Adenocarcinoma, PDAC

China
IHU Strasbourg

Terminated

Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts Images (BiliFast)

Cholangiocarcinoma | Pancreatitis | Cholangitis | Pancreatic Ductal Adenocarcinoma | Gallstone

France
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
zr Pharma & GmbH

Completed

A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States, Israel
Lisata Therapeutics, Inc.

Completed

CEND-1 in Combination With Nabpaclitaxel and Gemcitabine in Metastatic Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

Australia
PH Research, S.L.

Terminated

A Trial of PEGPH20 in Combination With Avelumab in Chemotherapy Resistant Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

Spain
ERYtech Pharma

Completed

Efficacy and Safety of L-asparaginase Encapsulated in RBC Combined With Gemcitabine or FOLFOX in 2nd Line for Progressive Metastatic Pancreatic Carcinoma

Pancreatic Adenocarcinoma Metastatic

France
Alpha Tau Medical LTD.

Recruiting

A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer

Israel
Paolo Giorgio Arcidiacono, MD

Terminated

EUS Role in Non-metastatic Pancreatic Adenocarcinoma Lymph Nodes Staging

Pancreatic Adenocarcinoma | Lymph Node Metastasis

Italy
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Colorectal Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Carcinoma | KRAS P.G12C

China
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); Vaccinex...

Completed

VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Colorectal Adenocarcinoma | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage II Pancreatic Cancer | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Stage I Pancreatic Cancer | Resectable Pancreatic... and other conditions

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Clinical Study of MK-2870 Alone or With Chemotherapy to Treat Gastrointestinal Cancers (MK-9999-02A)

Colorectal Cancer | Biliary Tract Cancer | Pancreatic Ductal Carcinoma
Shanghai General Hospital, Shanghai Jiao Tong University...
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China

Unknown

Immunotherapy of CD8+NKG2D+ AKT Cell With Chemotherapy to Pancreatic Cancer (AKT)

Pancreatic Ductal Adenocarcinoma

China
Ipsen

Withdrawn

Study to Assess the Safety and Efficacy of Intravenous Injection of the Imaging Agent 111In-IPN01087 in Patients With Locally Advanced or Metastatic Pancreatic or Colorectal Cancer.

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma

Belgium, France
Assistance Publique - Hôpitaux de Paris
Groupe Francophone Thrombose et Cancer

Terminated

Safety and Efficacy of Clopidogrel in Locally Advanced and Metastatic Pancreatic Adenocarcinoma Treated With Chemotherapy (PANCREADOGREL)

Metastatic Pancreatic Cancer | Locally Advanced Pancreatic Cancer | Adenocarcinoma, Pancreas

France

Clinical Trials on Untreated Metastatic Pancreatic Ductal Adenocarcinoma

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