Clinical Trials on Uterine or Soft Tissue Leiomyosarcoma

Total 9457 results

City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Stage IIIA Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IIIB Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IIIC Uterine Corpus Leiomyosarcoma... and other conditions

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma (LMS04)

Uterine or Soft Tissue Leiomyosarcoma

France
National Cancer Institute (NCI)

Recruiting

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Locally Advanced Uterine Corpus Leiomyosarcoma | Metastatic Uterine Corpus Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Uterine Corpus Leiomyosarcoma

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Uterine Corpus Leiomyosarcoma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Locally Advanced Leiomyosarcoma | Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Uterine Corpus Leiomyosarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Uterine Corpus Leiomyosarcoma

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

Uterine Corpus Leiomyosarcoma | Stage I Uterine Sarcoma AJCC v7

United States, Belgium, France, Spain, United Kingdom, Netherlands, Norway, Venezuela
GOG Foundation

Recruiting

Letrozole in Uterine Leiomyosarcoma

Uterine Leiomyosarcoma

United States
West China Second University Hospital

Active, not recruiting

Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids

Uterine Sarcoma | Uterine Fibroid | Uterine Leiomyosarcoma

China
Kristen Ganjoo

Recruiting

CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma

Uterine Leiomyosarcoma | LMS - Leiomyosarcoma

United States
Gynecologic Oncology Group
GlaxoSmithKline

Withdrawn

Pazopanib for Treating Uterine Leiomyosarcoma

Uterine Leiomyosarcoma
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Sunitinib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

Recurrent Uterine Sarcoma | Uterine Leiomyosarcoma

United States
Memorial Sloan Kettering Cancer Center

Completed

Adjuvant Docetaxel Plus Gemcitabine in Patients With Completely Resected Leiomyosarcoma (LMS) of the Uterus

Uterine Cancer | Uterine Leiomyosarcoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With Chemotherapy

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study of Doxorubicin and Trabectedin in First Line Treatment on Patients With Metastatic Leiomyosarcoma (LMS02)

Uterus Leiomyosarcoma | Soft Tissue Leiomyosarcoma

France
Massachusetts General Hospital
Jazz Pharmaceuticals

Recruiting

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma | Advanced Leiomyosarcoma | Leiomyosarcoma Metastatic

United States
National Cancer Institute (NCI)

Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Metastatic Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Unresectable Sarcoma

United States
Xian-Janssen Pharmaceutical Ltd.

Completed

A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma

Advanced or Metastatic Liposarcoma or Leiomyosarcoma

China
National Cancer Institute (NCI)
NRG Oncology

Terminated

Gemcitabine Hydrochloride and Docetaxel With or Without Bevacizumab in Treating Patients With Advanced or Recurrent Uterine Leiomyosarcoma

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma | Stage IIIA Uterine Sarcoma | Stage IIIB Uterine Sarcoma | Stage IIIC Uterine Sarcoma | Stage IVA Uterine Sarcoma | Stage IVB Uterine Sarcoma

United States
Janssen Research & Development, LLC
PharmaMar

Completed

A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma

Advanced Liposarcoma or Leiomyosarcoma

United States, Australia, Brazil, New Zealand
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Thalidomide in Treating Patients With Recurrent or Persistent Cancer of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
National Cancer Institute (NCI)

Terminated

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

High Grade Sarcoma | Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Myxofibrosarcoma | Metastatic Malignant Peripheral Nerve Sheath Tumor | Metastatic Synovial Sarcoma | Metastatic Undifferentiated... and other conditions

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Filgrastim or Pegfilgrastim in Treating Patients With Recurrent or Persistent Cancer of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride, Docetaxel, and Radiation Therapy in Treating Patients With Uterine Sarcoma That Has Been Removed By Surgery

Uterine Corpus Leiomyosarcoma | Stage IIA Uterine Sarcoma | Stage IIB Uterine Sarcoma | Stage IIIA Uterine Sarcoma | Stage IIIB Uterine Sarcoma | Stage IIIC Uterine Sarcoma | Stage IVA Uterine Sarcoma | Stage IVB Uterine Sarcoma | Stage IA Uterine Sarcoma | Stage IB Uterine Sarcoma | Stage IC Uterine Sarcoma

United States
Institut Bergonié
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt...

Recruiting

Targeting ATR in Soft-tissue Sarcomas (TARSARC)

Leiomyosarcoma, Adult

France
Italian Sarcoma Group
PharmaMar

Recruiting

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma (ISG-ARTICLE)

Soft Tissue Sarcoma | Leiomyosarcoma of Ovary

Italy
National Cancer Institute (NCI)

Completed

AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma

Uterine Carcinosarcoma | Endometrial Stromal Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Uterine Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage IV Uterine Sarcoma | Dermatofibrosarcoma Protuberans | Adult Rhabdomyosarcoma and other conditions

Canada, United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma

Uterine Carcinosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Uterine Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage IV Uterine Sarcoma | Adult Angiosarcoma | Adult Epithelioid Sarcoma | Adult Leiomyosarcoma | Adult Synovial Sarcoma and other conditions

United States
North Eastern German Society of Gynaecological...
Novartis Pharmaceuticals; medac GmbH

Recruiting

Pazopanib vs. Pazopanib Plus Gemcitabine (PazoDoble)

Leiomyosarcoma or Carcinosarcoma

Germany
Gachon University Gil Medical Center
Merck KGaA, Darmstadt, Germany; Chong Kun Dang Pharmaceutical Corp.

Recruiting

Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment (EAGLES)

Leiomyosarcoma Metastatic

Korea, Republic of
Sarcoma Alliance for Research through Collaboration

Completed

Adjuvant Chemotherapy for High Risk Uterine Leiomyosarcoma

Leiomyosarcoma | Uterine Neoplasm

United States
Igenomix

Recruiting

Accuracy of the Preoperative Molecular Diagnosis of Uterine Tumors by Liquid Biopsy (MYOSARCII)

Leiomyoma, Uterine | Leiomyosarcoma Uterus

Spain
M.D. Anderson Cancer Center
Novartis

Terminated

Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma

Leiomyosarcoma | Uterine Neoplasm

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); EMD Serono

Terminated

Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Metastatic Liposarcoma | Unresectable Liposarcoma

United States
M.D. Anderson Cancer Center
Aadi Bioscience

Not yet recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Leiomyosarcoma | Soft-tissue Sarcomas

United States
Sarcoma Alliance for Research through Collaboration

Completed

SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma

Metastatic Leiomyosarcoma

United States
Polaris Group

Recruiting

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

Soft Tissue Sarcoma

United States
Fox Chase Cancer Center

Active, not recruiting

Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)

Soft Tissue Sarcoma

United States
National Taiwan University Hospital
Taipei Veterans General Hospital, Taiwan

Active, not recruiting

Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma (LEADER)

Advanced Cancer | Leiomyosarcoma | Soft Tissue Sarcoma Adult | Liposarcoma

Taiwan
Medical University of Graz

Terminated

Vorinostat (SAHA) in Uterine Sarcoma

Leiomyosarcoma | Endometrial Stromal Tumors | Carcinosarcomas Uterine

Austria
Fred Hutchinson Cancer Center
Incyte Corporation

Active, not recruiting

Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas

Refractory Soft Tissue Sarcoma | Metastatic Leiomyosarcoma | Metastatic Synovial Sarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Advanced Synovial Sarcoma | Metastatic Chondrosarcoma | Advanced Leiomyosarcoma | Metastatic Myxoid... and other conditions

United States
Grupo Espanol de Investigacion en Sarcomas
Centre Leon Berard; Italian Sarcoma Group

Recruiting

Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

Sarcoma, Soft Tissue | Leiomyosarcoma | Liposarcoma | Liposarcoma, Myxoid | Pleomorphic Liposarcoma

France, Spain, Italy
Broto, Javier Martín, M.D.

Unknown

Trial of Nilotinib and Adriamycin as Treatment in Liposarcomas and Leiomyosarcomas of Retroperitoneum (GEIS-27)

Chondrosarcoma | Retroperitoneal Liposarcoma | Retroperitoneal Leiomyosarcoma

Spain
David Liebner, MD

Withdrawn

Niraparib for the Treatment of Leiomyosarcoma

Locally Advanced Leiomyosarcoma | Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Stage III Retroperitoneal Sarcoma AJCC v8 | Stage IIIA Retroperitoneal Sarcoma AJCC v8 | Stage IIIB Retroperitoneal Sarcoma AJCC v8 | Stage IV Retroperitoneal Sarcoma AJCC v8

United States
Sarcoma Oncology Research Center, LLC

Recruiting

Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Leiomyosarcoma (TAGGED)

Leiomyosarcoma

United States
Mario Negri Institute for Pharmacological Research
PharmaMar

Completed

Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma (TAUL)

Leiomyosarcoma

Italy
Dana-Farber Cancer Institute
Novartis; Brigham and Women's Hospital

Completed

Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma

Leiomyosarcoma

United States
Power Life Sciences Inc.

Not yet recruiting

Exploring Clinical Trial Experiences of People With Leiomyosarcoma

Leiomyosarcoma
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Temozolomide for Injection Combined With Epirubicin in First-line Treatment of Leiomyosarcoma

Leiomyosarcoma

China

Clinical Trials on Uterine or Soft Tissue Leiomyosarcoma

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