Clinical Trials on Uterine Fibroids in South Africa

Total 630 results

University of Pretoria
University of Stellenbosch

Recruiting

Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women. (DiaVACCS)

Cervical Cancer | CIN2 | High Grade Sil

South Africa
UNC Lineberger Comprehensive Cancer Center
Fogarty International Center of the National Institute of Health

Completed

Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa (FIND)

Cervical Cancer

South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa

Cervical Cancer | CIN2 | CIN3

South Africa
Jeffrey Kotzen
National Research Foundation of South Africa; NTP Radioisotopes SOC Ltd

Unknown

Modulated Electro-Hyperthermia Plus Chemo-radiation for Locally Advanced Cervical Cancer Patients in South Africa (mEHT)

Cervical Cancer

South Africa
Columbia University
Bill and Melinda Gates Foundation; University of Cape Town; EngenderHealth

Terminated

Screen and Treat for Cervical Cancer Prevention (SAT)

Cervical Cancer

South Africa
Maastricht Radiation Oncology

Completed

Predicting Outcome in Cervix Carcinoma: a Prospective Study (POCER)

Cervical Cancer

Netherlands, South Africa
University of Witwatersrand, South Africa

Unknown

A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women

Cervical Dysplasia

South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI); Montefiore Medical Center; University of Arkansas and other collaborators

Completed

Cisplatin and Radiation Therapy in Treating Patients With HIV-Associated Locally Advanced Cervical Cancer

Acquired Immunodeficiency Syndrome | Cervical Cancer

South Africa, Zimbabwe
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
GlaxoSmithKline
University of Cape Town; African Organization for Research and Training in...

Completed

Type Distribution of Human Papillomavirus in Adult African Women Diagnosed With Invasive Cervical Cancer

Cervical Cancer | Infections, Papillomavirus

Ghana, Nigeria, South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
Boston University Charles River Campus
Massachusetts General Hospital; University of Witwatersrand, South Africa

Not yet recruiting

Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women With HIV in South Africa: Part 2

Cervical Cancer | Hiv

United States, South Africa
International Atomic Energy Agency

Unknown

Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients

Cancer of the Cervix

India, South Africa, Tanzania, Uganda, Zimbabwe
Antiva Biosciences

Recruiting

A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Australia, South Africa
Myovant Sciences GmbH

Completed

LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Italy, Poland, Brazil, South Africa, United Kingdom
University of Pretoria

Completed

A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

Prevention of Post Partum Haemorrhage

South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; University of Stellenbosch

Withdrawn

Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women

HIV Infection | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | FIGO Stage IIB Cervix Carcinoma | FIGO Stage III Cervix Carcinoma | FIGO Stage IVA Cervix Carcinoma

South Africa, Zimbabwe
Myovant Sciences GmbH

Completed

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Belgium, Czechia, South Africa, Chile, Brazil, Hungary, Poland
Myovant Sciences GmbH

Completed

LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Italy, Belgium, Czechia, Hungary, Poland, South Africa, Chile, Brazil
Myovant Sciences GmbH

Completed

Bone Mineral Density in Women With Uterine Fibroids or Endometriosis

Endometriosis | Uterine Fibroid

United States, Hungary, Australia, Chile, Czechia, Georgia, Poland
Gynuity Health Projects
University of Witwatersrand, South Africa; Effective Care Research Unit; Family...

Completed

Misoprostol for Preventing Postpartum Hemorrhage

Postpartum Hemorrhage

Uganda, Nigeria, South Africa
Faculty of Medicine

Completed

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Uterine Hemorrhage | Adverse Effect of Oxytocic Drugs | Inappropriate Dose of Drug Administered

Uganda
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
International Atomic Energy Agency

Completed

CRP on Radiobiological and Clinical Studies on Viral-Induced Cancer's Response to Radiotherapy

Cervix Cancer

Peru, Korea, Republic of, Morocco, Austria, Brazil, Canada, India, Macedonia, The Former Yugoslav Republic of, Pakistan, South Africa, United Kingdom
University of Birmingham
King's College London; University College, London; University of Nairobi; World... and other collaborators

Completed

A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth (E-MOTIVE)

Post-Partum Haemorrhage

South Africa, Kenya, Tanzania, Nigeria
Myovant Sciences GmbH

Completed

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Uterine Leiomyoma

United States, Italy, Poland, Czechia, Hungary, South Africa, Brazil, Chile
Sheffield Teaching Hospitals NHS Foundation Trust
World Cancer Research Fund International

Terminated

Folate and Protection Against Cervical Cancer

Cervical Cancer

United Kingdom
Bayer

Completed

MiCo - Mirena or Conventional Medical Treatment for Menorrhagia

Idiopathic Menorrhagia

Croatia, South Africa, Colombia, Czech Republic, Jordan, Lebanon, Macedonia, The Former Yugoslav Republic of, Moldova, Republic of, Romania, Ukraine, Venezuela, Bosnia and Herzegovina, Syrian Arab Republic, Albania
Terumo Medical Corporation

Completed

An Observational Study of Radial Access Embolization Procedures Using HydroPearl Microspheres (RAVI Registry)

Benign Prostatic Hyperplasia | Arteriovenous Malformations | Uterine Fibroid | Hypervascular Tumors

United States
Queensland Centre for Gynaecological Cancer

Completed

Uterine Papillary Serous Cancer (UPSC) Trial

Uterine Cancer

Australia
University of Athens

Unknown

Clinical Performance of a One-step Self-etch Adhesive in Non-carious Cervical Lesions at 2 Years

Non-carious Cervical Lesions | Adhesive Performance

Greece
Repros Therapeutics Inc.

Completed

Extension Study of Proellex in Women Who Have Previously Completed Study ZPU 003

Uterine Fibroids

United States
University of Sydney
National Health and Medical Research Council, Australia; Family Planning Association...

Unknown

The IMAP Study Improving Management of Mildly Abnormal Pap Smears

Cervix Neoplasms

Australia
Niels Jørgen Secher

Terminated

Cervical Occlusion for the Prevention of Preterm Birth

Uterine Cervical Incompetence

United Kingdom, India, Australia, South Africa, Denmark, Saudi Arabia, Spain, Sweden, Switzerland
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa
Repros Therapeutics Inc.

Terminated

Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids

Uterine Fibroids

United States
Repros Therapeutics Inc.

Completed

Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids

Uterine Fibroids

United States
Repros Therapeutics Inc.

Completed

A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids

Uterine Fibroids

United States
Hoffmann-La Roche

Completed

Safety and Efficacy of Bevacizumab in Combination With Carboplatin and Paclitaxel for Metastatic, Recurrent or Persistent Cervical Cancer

Cervical Cancer

Argentina, Panama, Portugal, Spain, Turkey, Brazil, Colombia, Romania, Italy, Poland, France, Bulgaria, South Africa, Mexico, Russian Federation, Serbia, Costa Rica, Greece
Trans Tasman Radiation Oncology Group
Peter MacCallum Cancer Centre, Australia

Completed

Magnetic Resonance Imaging (MRI) Staging of Cervix Cancer

Cancer of the Uterine Cervix

United States, Singapore, Australia, New Zealand, India
Nordic Society of Gynaecological Oncology - Clinical...
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Endometrial Cancer

Endometrial Cancer

France, Norway, Belgium, Spain, Netherlands, Italy, United Kingdom, Ireland, Poland, Portugal, South Africa
AbbVie

Completed

An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Canada, Puerto Rico
Repros Therapeutics Inc.

Terminated

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

Uterine Fibroids

United States
AbbVie

Completed

A Study to Evaluate the Safety and Efficacy of Elagolix for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Uterine Fibroids

United States, Puerto Rico
Sydney Centre for Reproductive Health Research
Merck Sharp & Dohme LLC

Unknown

A New Treatment Option for Heavy Menstrual Bleeding

Menorrhagia

Australia
University of West Attica

Unknown

Implementing Enhanced Recovery After Surgery (ERAS) Pathways In Major Gynecologic Oncology Operations In Greece (ERAS)

Gynecologic Cancer | Ovarian Cancer | Endometrial Cancer | Hysterectomy

Greece
ObsEva SA

Completed

Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids (PRIMROSE 2)

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Bulgaria, Czechia, Hungary, Latvia, Lithuania, Poland, Romania, Ukraine
Glenveigh Medical

Terminated

Belfort Dildy- Obstetrical Tamponade System Post-Marketing Surveillance Program

Postpartum Uterine Bleeding

United States
GlaxoSmithKline

Completed

Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants

Cervical Cancer | Precancerous Condition

Costa Rica

Clinical Trials on Uterine Fibroids in South Africa

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