Clinical Trials on Vascular Myelopathy

Total 50408 results

National Institute of Neurological Disorders and...

Completed

Treatment of AIDS Vacuolar Myelopathy With Methionine

Myelopathy | AIDS-Myelopathy | AIDS Vacuolar Myelopathy

United States
Ultragenyx Pharmaceutical Inc

Terminated

A Study to Evaluate the Safety of Aceneuramic Acid Extended Release (Ace-ER; UX001) Tablets in Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy (GNEM) (Also Known as Hereditary Inclusion Body Myopathy [HIBM]) Patients With Severe Ambulatory Impairment

Hereditary Inclusion Body Myopathy | GNE Myopathy | Inclusion Body Myopathy 2 | Distal Myopathy With Rimmed Vacuoles | Distal Myopathy, Nonaka Type | Quadriceps Sparing Myopathy

Canada, United States, Bulgaria
Boston Children's Hospital
Muscular Dystrophy Association

Recruiting

Molecular and Genetic Studies of Congenital Myopathies

Centronuclear Myopathy | Myotubular Myopathy | Nemaline Myopathy | Central Core Disease | Congenital Fiber Type Disproportion | Multiminicore Disease | Rigid Spine Muscular Dystrophy | Undefined Congenital Myopathy

United States
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Myotubular and Centronuclear Myopathy Patient Registry

X-linked Myotubular Myopathy | Centronuclear Myopathy | Myotubular Myopathy | Myotubular Myopathy 1 | Myotubular (Centronuclear) Myopathy | Centronuclear Myopathy, X-Linked

United Kingdom
Ultragenyx Pharmaceutical Inc

Terminated

Study to Evaluate the Safety and Efficacy of Aceneuramic Acid Extended-Release (Ace-ER) Tablets in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)

Hereditary Inclusion Body Myopathy | GNE Myopathy | Distal Myopathy With Rimmed Vacuoles | Distal Myopathy, Nonaka Type | Quadriceps Sparing Myopathy

United States, Canada, United Kingdom, Israel, Italy, Bulgaria, France
Ultragenyx Pharmaceutical Inc

Completed

Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Sialic Acid in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM) (GNEM)

Hereditary Inclusion Body Myopathy | GNE Myopathy | Distal Myopathy With Rimmed Vacuoles | Distal Myopathy, Nonaka Type

United States, Canada, United Kingdom, Israel, Italy, Bulgaria, France
Vastra Gotaland Region

Enrolling by invitation

Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment (COMPIS)

Musculoskeletal Diseases | Neuromuscular Diseases | Centronuclear Myopathy | Nemaline Myopathy | Congenital Myopathy | Myosin Storage Myopathy

Sweden
Nobelpharma

Completed

Efficacy Confirmation Study of NPC-09

GNE Myopathy | Nonaka Disease | Distal Myopathy With Rimmed Vacuoles (DMRV) | Hereditary Inclusion Body Myopathy (hIBM)

Japan
Ultragenyx Pharmaceutical Inc
Newcastle University

Completed

GNE-Myopathy Disease Monitoring Program (GNEM-DMP): A Registry and Prospective Observational Natural History Study to Assess GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)

Hereditary Inclusion Body Myopathy | GNE Myopathy | Nonaka Disease | Quadriceps Sparing Myopathy (QSM) | Distal Myopathy With Rimmed Vacuoles (DMRV)

United States, Bulgaria, Canada, France, United Kingdom
Peking University First Hospital
Peking University

Completed

Decompressive Cervical Surgery and Hypertension

Hypertension | Myelopathy, Compressive

China
James Dowling
Canadian Institutes of Health Research (CIHR); Cures Within Reach; The Joshua... and other collaborators

Recruiting

Tamoxifen Therapy for Myotubular Myopathy (TAM4MTM)

X Linked Myotubular Myopathy

United Kingdom, Canada, United States
Assiut University

Not yet recruiting

Magnetic Resonance Imaging and Ultrasonography in Evaluation of Muscle Diseases

Myositis | Congenital Myopathy | Acquired Myopathy
Rigshospitalet, Denmark

Active, not recruiting

Contractile Cross Sectional Areas and Muscle Strength in Patients With Congenital Myopathies

Congenital Myopathy | Inherited Muscle Diseases | RYR1-myopathy

Denmark
Shanghai Changzheng Hospital

Recruiting

Cervical Laminoplasty Versus Laminectomy and Fusion: the Long-term Results Comparison

Myelopathy Cervical

China
Clinic for Special Children

Recruiting

WiTNNess - TNNT1 Myopathy Natural History Study (WiTNNess)

Myopathy | Myopathy; Hereditary | Myopathies, Nemaline | TNNT1-associated Myopathy | Infantile-onset Nemaline Rod Myopathy | Myopathy, Rod | Amish Nemaline Myopathy | Nemaline Myopathy 5 | NEM5 | Genetic Muscle Disease | Recessive Hereditary Disorder (Autosomal) | ANM

United States
Texas Tech University Health Sciences Center

Recruiting

Annatto-derived GG for Statin-associated Myopathy (GG-statin)

Myopathy; Primary

United States
Astellas Gene Therapies

Completed

A Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects (INCEPTUS)

X-linked Myotubular Myopathy

United States, France, United Kingdom, Canada, Germany
University of Florida
Audentes Therapeutics

Completed

Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM)

X-linked Myotubular Myopathy

United States
Lawson Health Research Institute

Completed

Evaluation of Patients With Statin Myopathy Using an N of 1 Trial Design

Statin Myopathy

Canada
Radboud University Medical Center
UMC Utrecht

Not yet recruiting

The Natural History and Muscle Fatigability of Patients With Congenital Myopathies. (READYCOM)

Centronuclear Myopathy | Nemaline Myopathy | Central Core Disease | Multi-Minicore Disease

Netherlands
Ra Pharmaceuticals

Terminated

Safety and Efficacy Study of Zilucoplan in Subjects With Immune-Mediated Necrotizing Myopathy

Immune Mediated Necrotizing Myopathy

United States, Netherlands, France, United Kingdom
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes

Completed

Descriptive Study of Acute Spontaneous Spinal Cord Infarction (EDMIAS)

Spinal Cord Infarction | Spinal Cord Stroke | Vascular Myelopathy

France
Peking University Third Hospital

Completed

Long Term Clinical Outcome of Single Open Door Laminoplasty With Preservation of Unilateral Muscular Ligament Complex

Cervical Myelopathy

China
Ultragenyx Pharmaceutical Inc

Completed

An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States, Israel
Armgo Pharma, Inc.
National Institute of Nursing Research (NINR); National Institute of Neurological... and other collaborators

Completed

S 48168 (ARM 210) for the Treatment of RYR1-related Myopathies (RYR1-RM)

RYR-1 Myopathy

United States
Astellas Gene Therapies

Completed

A Medical Chart Review of Patients With X-Linked Myotubular Myopathy (XLMTM)

Males With X-linked Myotubular Myopathy (XLMTM)

United States, United Kingdom
National Human Genome Research Institute (NHGRI)
National Center for Advancing Translational Sciences (NCATS); Therapeutics...

Completed

Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States
Cure CMD
University of Michigan; Congenital Muscle Disease International Registr

Completed

Myotubular Myopathy Event Study (MTMES)

X-linked Myotubular Myopathy

United States
Rockefeller University

Terminated

Metabolic Features of Post-Myopathy Patients Associated With Statin Treatment

Myopathy (Statin Associated)

United States
Astellas Gene Therapies

Active, not recruiting

Gene Transfer Clinical Study in X-Linked Myotubular Myopathy (ASPIRO)

X-Linked Myotubular Myopathy

United States, Canada, France, Germany
Cambridge University Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom; Wolfson Brain Imaging...

Recruiting

Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy (IMAGE-DCM)

Cervical Spondylosis With Myelopathy | Degenerative Cervical Myelopathy

United Kingdom
Oregon Health and Science University

Completed

Neurosciences-Intensive Care Unit Electrical Stimulation

Intensive Care (ICU) Myopathy

United States
University of Melbourne
Melbourne Health; National University Hospital, Singapore; Flinders Medical Centre and other collaborators

Completed

Physical Function in Critical Care (PaciFIC) (PaciFIC)

Intensive Care (ICU) Myopathy

Singapore, Australia, Brazil
Yodakubo Hospital

Completed

Effect of Tranexamic Acid on Reducing Postoperative Blood Loss in Cervical Laminoplasty

Cervical Myelopathy
Rigshospitalet, Denmark

Completed

Aerobic Training in Patients With Congenital Myopathies

Congenital Myopathy

Denmark
Reneo Pharma Ltd

Terminated

An Open Label, Long Term Safety Study of REN001 in Primary Mitochondrial Myopathy Patients (Stride Ahead)

Primary Mitochondrial Myopathy

Spain, Australia, Belgium, Denmark, Canada, United Kingdom, France, Germany, Hungary, Italy, Netherlands, New Zealand
The University of Hong Kong

Recruiting

Proprioceptive Deficits in Degenerative Cervical Myelopathy

Cervical Myelopathy

Hong Kong
Charite University, Berlin, Germany
University Hospital Inselspital, Berne; University Hospital of Cologne; University... and other collaborators

Recruiting

Cerebral Reorganization in Cervical Myelopathy Measured by Navigated Transcranial Magnetic Stimulation (CReMe)

Degenerative Myelopathy

Germany
Seoul National University Hospital

Completed

The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy

Cervical Myelopathy

Korea, Republic of
National Taiwan University Hospital

Completed

Clinical Evaluation and Rehabilitation System for Dynamic Balance Control in Cervical Myelopathy Patients

Cervical Myelopathy

Taiwan
Newcastle University

Unknown

International GNE Myopathy Patient Registry

Hereditary Inclusion Body Myopathy | GNE Myopathy

United Kingdom
Tohoku University

Completed

Pharmacokinetic Study on N-acetylneuraminic Acid

Hereditary Inclusion Body Myopathy | Nonaka Myopathy

Japan
Ruth Salim

Unknown

MR in Patients With Collagen VI Related Myopathies

Bethlem Myopathy | Ullrich Disease

Denmark
Universidade Estadual do Oeste do Paraná

Completed

Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients

Intensive Care (ICU) Myopathy | Functional Independence
Hartford Hospital

Unknown

CoEnzyme Q10 in Statin Myopathy

Statin Myopathy

United States
Hartford Hospital
University of Connecticut

Unknown

NIRS to Diagnose SAMS

Statin Adverse Reaction | Skeletal Myopathy

United States
The Emmes Company, LLC
United Mitochondrial Disease Foundation; PolG Foundation Mito Australia

Recruiting

Mitochondrial Video Assessment Source Material Study

PolG, Primary Mitochondrial Myopathy

United States
Uppsala University Hospital
Karolinska Institutet; Linkoeping University; Sahlgrenska University Hospital...

Recruiting

Fusion or no Fusion After Decompression of the Spinal Cord in Patients With Degenerative Cervical Myelopathy (MyRanC)

Cervical Spondylotic Myelopathy

Sweden
Peking University Third Hospital

Completed

Motor Function Assessment System Based on Video Tracking and Artificial Intelligence Technique

Cervical Spine Myelopathy

China
AOSpine North America Research Network

Completed

Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect) (CSM-Protect)

Cervical Spondylotic Myelopathy

United States, Canada

Clinical Trials on Vascular Myelopathy

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CROs in Belgium

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