- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00032695
Treatment of AIDS Vacuolar Myelopathy With Methionine
May 12, 2006 updated by: National Institute of Neurological Disorders and Stroke (NINDS)
The purpose of this study is to determine whether methionine, an amino acid present in low doses in the normal diet, can improve myelopathy or stop its progression.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Myelopathy is usually a late complication of AIDS, and until recently its symptoms were rarely recognized, masked by the general state of disability or the presence of other neurological complications.
With prolonged survival and improved quality of life of HIV-infected patients, myelopathy is increasingly becoming a common source of disability.
The cause of AIDS-myelopathy is unknown, but it is probably an indirect effect of the long-term presence of the HIV virus in the nervous system rather than the result of a direct infection.
The purpose of this study is to determine whether methionine, an amino acid present in low doses in the normal diet, can improve myelopathy or stop its progression.
Study Type
Interventional
Enrollment
56
Phase
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
New York
-
New York, New York, United States, 10003
- Beth Israel Medical Center
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (ADULT, OLDER_ADULT)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Between 18 and 80 years of age
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: TREATMENT
- Allocation: RANDOMIZED
- Masking: DOUBLE
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Alessandro Di Rocco, MD
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
March 28, 2002
First Submitted That Met QC Criteria
March 28, 2002
First Posted (ESTIMATE)
March 29, 2002
Study Record Updates
Last Update Posted (ESTIMATE)
May 15, 2006
Last Update Submitted That Met QC Criteria
May 12, 2006
Last Verified
November 1, 2005
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- R01NS035745 (NIH)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Myelopathy
-
Peking University Third HospitalCompleted
-
Shanghai Changzheng HospitalRecruitingMyelopathy CervicalChina
-
Cambridge University Hospitals NHS Foundation TrustNational Institute for Health Research, United Kingdom; Wolfson Brain Imaging...RecruitingCervical Spondylosis With Myelopathy | Degenerative Cervical MyelopathyUnited Kingdom
-
University of KentuckyRecruiting
-
Imperial College Healthcare NHS TrustNot yet recruitingCervical Myelopathy
-
University of UtahEnrolling by invitationCervical MyelopathyUnited States
-
The University of Hong KongCompleted
-
The University of Hong KongThe Hong Kong Polytechnic UniversityCompletedCervical MyelopathyHong Kong
-
Istanbul UniversityCompleted
-
Greenwich HospitalYale UniversityCompletedCervical Spondylotic MyelopathyUnited States
Clinical Trials on methionine
-
Pennington Biomedical Research CenterOrentreich Foundation for the Advancement of Science, Inc.CompletedMetabolic Syndrome
-
St. Jude Children's Research HospitalRecruitingHodgkin Lymphoma | Osteosarcoma | Ewing Sarcoma | Ependymoma | Medulloblastoma | Non Hodgkin Lymphoma | Neuroblastoma | Craniopharyngioma | Rhabdomyosarcoma | Other | Brain Stem Glioma | Brain Tumors and/or Solid Tumors Including | High Grade CNS Tumors | Low Grade CNS TumorsUnited States
-
Masaryk Memorial Cancer InstituteActive, not recruiting11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET) (GlioMET)Glioblastoma MultiformeCzechia
-
St. Jude Children's Research HospitalAvailableHead and Neck Neoplasms | Central Nervous System TumorUnited States
-
Dana-Farber Cancer InstituteMassachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham...Completed
-
Memorial Sloan Kettering Cancer CenterCompleted
-
Beijing Insight Science & Technology Co. Ltd.Unknown
-
Turku University HospitalUnknownPulmonary SarcoidosisFinland
-
Hospices Civils de LyonRecruiting