Clinical Trials on Vulnerable Coronary Plaques in Japan

Total 215 results

National Cerebral and Cardiovascular Center

Unknown

Atheroma Progression and Vulnerability Under Continuous Glucose Monitoring (OPTIMAL)

Coronary Atherosclerosis

Japan
Kobe University

Unknown

The Efficacy of Alirocumab for Thin-cap fIbroatheroma in Patients With Coronary Artery Disease Estimated by Optical Coherence Tomography (ALTAIR)

Coronary Artery Disease | Thin-cap fIbroatheroma

Japan
Kyoto University
Yamaguchi University Hospital

Completed

Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Ex JAPAN-ACS)

Acute Coronary Syndrome | Cardiovascular Events | Statin | Intravascular Ultrasound | Coronary Plaque

Japan
Seung-Jung Park
CardioVascular Research Foundation, Korea

Completed

Preventive PCI or Medical Therapy Alone for Vulnerable Atherosclerotic Coronary Plaque (PREVENT)

Coronary Artery Disease | Plaque, Atherosclerotic

Korea, Republic of, Taiwan, United States, Japan, New Zealand
Abbott Medical Devices

Completed

XIENCE PRIME Japan Post-Marketing Surveillance (PMS)

Myocardial Ischemia | Coronary Artery Disease | Coronary Occlusion | Coronary Artery Stenosis | Angina

Japan
Novartis Pharmaceuticals

Recruiting

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (V-PLAQUE)

Coronary Artery Disease

United States, Italy, Spain, France, Korea, Republic of, Hungary, Japan, Argentina, China, India, Belgium, Switzerland, United Kingdom, Canada, Australia, Brazil, Chile, Ireland
National Defense Medical College, Japan

Unknown

Anti-inflammatory Effect of Atorvastatin in Atherosclerotic Plaques Assessed by FDG-PET Imaging

Inflammation | Atherosclerosis

Japan
Juntendo University
Japan Heart Foundation

Completed

Azelnidipine Anti-Coronary Atherosclerotic Trial in Hypertensive Patients by Serial Volumetric IVUS Analysis(ALPS-J)

Hypertension | Coronary Atherosclerosis

Japan
Takeshi Morimoto

Terminated

Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound (PREVUS)

Coronary Artery Disease | Hypertension

Japan
National Cerebral and Cardiovascular Center

Recruiting

REASSURE-NIRS Registry (REASSURENIRS)

Lipid-Rich Atherosclerosis of Coronary Artery

Japan
CathWorks Ltd.

Completed

Angiogram Based Fractional Flow Reserve in Patients With Multi-Vessel Disease

Multi Vessel Coronary Artery Disease

Japan
Kyoto University, Graduate School of Medicine

Active, not recruiting

ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS (STOPDAPT-2 ACS)

Coronary Artery Disease | Acute Coronary Syndrome | Percutaneous Coronary Intervention | Acute Myocardial Infarction | Platelet Aggregation Inhibitors

Japan
Kobe University

Unknown

Healing Response to Everolimus-eluting Stent Implantation; Serial Assessment With opticaL Coherence Tomography (HEAL)

Coronary Heart Disease

Japan
Kurashiki Central Hospital

Unknown

Bifurcation Stenting Using 2 Link Stent Nobori Versus 3 Link Stent Xience (BEGIN)

Coronary Stenosis

Japan
Yokohama City University Medical Center

Unknown

The Effects of Ezetimibe on Coronary Plaque Volume in Patients With Acute Coronary Syndrome

Coronary Artery Disease

Japan
Hyogo College of Medicine

Withdrawn

Relationship Between Pressure and Flow Velocity on Coronary Physiology

Coronary Stenosis

Japan
Kobe University
Marquette University

Unknown

Relation Among Shear Stress Distribution, Stent Design, and Subsequent Vessel Healing After Drug-eluting Stent Implantation (SHEAR DES)

Coronary Heart Disease

Japan
Yokohama City University Medical Center
Teikyo University

Completed

Assessment of Distal Protection Device in Patients at High Risk for Distal Embolism in Acute Coronary Syndrome (ACS) (VAMPIRE3)

Coronary Artery Disease

Japan
Kobe University

Recruiting

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy (POLARIS)

Coronary Artery Disease Progression

Japan
Mitsui Memorial Hospital
Teikyo University; Tokai University

Unknown

Effect of Combination of Non-sLip Element Balloon (NSE) and druG-coated bAlloon (DCB) for In-steNT Restenosis Lesions (ELEGANT)

Coronary Restenosis

Japan
Kyoto University, Graduate School of Medicine

Active, not recruiting

ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study (STOPDAPT-2)

Coronary Artery Disease

Japan
Kobe University

Unknown

Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent

Coronary Artery Disease

Japan
Fujita Health University

Unknown

Comparison Between OFDI and IVUS in PCI Guidance for Biolimus A9 Eluting Stent Implantation (MISTIC-1)

Coronary Artery Disease

Japan
Teikyo University

Unknown

3-Month Discontinuation of Dual Antiplatelet Therapy After Ultimaster Sirolimus-Eluting Stent Implantation (MODEL U-SES)

Coronary Artery Disease

Japan
Takeshi Morimoto

Completed

Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial (ReACT)

Coronary Artery Disease

Japan
Takeshi Morimoto

Completed

Short and Optimal Duration of Dual Antiplatelet Therapy Study (STOPDAPT)

Coronary Artery Disease

Japan
Takeshi Morimoto

Completed

Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting Stent Trial (RESET)

Coronary Artery Disease

Japan
Kumamoto University

Completed

Impaired Peripheral Endothelial Function and In-stent Restenosis

Coronary Artery Disease

Japan
Kumamoto University

Completed

Endothelial Dysfunction and Coronary Artery Spasm

Coronary Vasospasm

Japan
Ono Pharmaceutical Co. Ltd

Completed

Study of ONO-1101 in Patients Scheduled for Coronary Angiography

Coronary Artery Disease

Japan
Takeshi Morimoto

Completed

Clopidogrel High Dose Evaluation for the Patient With Coronary Artery Disease in Japan (CHOICE)

Coronary Artery Disease

Japan
Takeshi Morimoto

Completed

NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-eluting Stent Trial (NEXT)

Coronary Artery Disease

Japan
Kumamoto University
Japan Heart Foundation; The 4C trial bureau

Completed

Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial

Coronary Artery Disease | Hypertension

Japan
Hyogo College of Medicine

Withdrawn

Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents (ASSESS)

Coronary Artery Disease | Atherosclerosis

Japan
Hiroshima University

Unknown

Plaque Registration and Event Detection In Computed Tomography (PREDICT)

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis

Japan
Kumamoto University

Completed

Evaluation of Cardiac CT Appropriateness at Second-generation 320-row CT

Coronary Artery Disease | Cardiac CT

Japan
Bristol-Myers Squibb

Recruiting

A Study of the Comparative Effectiveness of Deucravacitinib in Adults With Plaque Psoriasis in Japan (RePhlect) (RePhlect)

Plaque Psoriasis

Japan
Kurashiki Central Hospital
Japanese CTO PCI Expert Registry investigators

Recruiting

Japanese CTO PCI Expert Registry

Chronic Total Occlusion of Coronary Artery

Japan
Kobe University
HeartFlow, Inc.

Completed

Comparisons of Morphological Measurement Between Coronary Computed Tomography and Optical Coherence Tomography

Coronary Artery Disease

Japan
Saiseikai Yokohama City Eastern Hospital

Completed

Comparison Between Provisional Versus Routine Kissing Balloon Technique After Main Vessel Crossover Stenting for Bifurcated Lesions. (PROTECT-SB)

Coronary Artery Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Phase 2 Clinical Study of KHK4827

Moderate to Severe Plaque Psoriasis

Japan
Associations for Establishment of Evidence in Interventions

Completed

Japan Study of Distal Evaluation of Functional Significance of Intra-arterial Stenosis Narrowing Effect

Coronary Artery Disease

Japan
Ono Pharmaceutical Co. Ltd

Completed

Study of ONO-1101 in Patients Scheduled for Multi-Slice Computed Tomography (CT)

Coronary Artery Disease

Japan
Medtronic Vascular

Completed

RESOLUTE Japan SVS: The Clinical Evaluation of the MDT-4107 DES in the Treatment of De Novo Lesions in Small Diameter Native Coronary Arteries (RJ-SVS)

Myocardial Ischemia | Cardiovascular Diseases | Coronary Artery Disease | Arterial Occlusive Diseases

Japan
Satoshi Shizuta
Daiichi Sankyo Co., Ltd.; Research Institute for Production Development

Completed

Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study (OAC-ALONE)

Coronary Artery Disease | Atrial Fibrillation

Japan
Juntendo University
Kumamoto University; Tokyo University; Kyoto University; Tohoku University; Yamaguchi...

Completed

Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy With Pitavastatin in Coronary Artery Disease (REAL-CAD)

Coronary Artery Disease

Japan
Iwate Medical University

Unknown

Comparison of MECHANISM of Early and Late Vascular Responses Following Treatment of ST-elevation Acute Myocardial Infarction With Two Different Everolimus-eluting Stents: Randomized Controlled Trial Between Biodegradable Polymer and Durable Polymer Stent (MECHANISM-AMI-RCT)

Coronary Artery Disease

Japan
Iwate Medical University

Completed

Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent and Platelet AggregatioN studIeS for TreatMent of Acute Myocardial InfarctionTreatment of ST-elevation Acute Myocardial Infarction (MECHANISM-AMI)

Coronary Artery Disease

Japan
Associations for Establishment of Evidence in Interventions

Unknown

Japan Unprotected Left Main Coronary Artery Disease Percutaneous Coronary Intervention (PCI) Strategy On New Generation Stents (J-LESSON)

Coronary Artery Disease

Japan
Translational Research Center for Medical Innovation...
Wakayama Medical University

Completed

OPtical Frequency Domain Imaging vs. INtravascular Ultrasound in Percutaneous Coronary InterventiON (OPINION)

Coronary Artery Disease

Japan

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