Clinical Trials on Wet Macular Degeneration in South Africa

Total 2305 results

Medtronic Cardiac Rhythm and Heart Failure
Medtronic

Completed

IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE-HF)

Myocardial Infarction | Ventricular Dysfunction, Left | Heart Failure, Congestive

United States
Bayer

No longer available

Riociguat in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (EAS)

Hypertension, Pulmonary

Belgium, France, Italy, Spain, United States, Switzerland, Turkey, Portugal, Canada, Sweden, Germany, Austria, Denmark, Mexico, Russian Federation, Colombia, United Kingdom, Netherlands, Japan, Czech Republic
Amgen
Colorado Prevention Center

Active, not recruiting

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction (EVOLVE-MI)

Myocardial Infarction | Stroke | Cardiovascular Disease | Coronary Revascularization

United States, Sweden, Brazil
GlaxoSmithKline

Active, not recruiting

A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody

Multiple Myeloma

United States, Spain, France, Germany, Australia, United Kingdom, Canada, Italy
Biotronik, Inc.

Terminated

Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk (IMPACT)

Stroke | Atrial Fibrillation | Atrial Flutter | Major Bleeding | Embolism, Systemic Arterial

United States, Canada, United Kingdom, Denmark, Germany, Australia
Novartis Pharmaceuticals

Recruiting

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (V-PLAQUE)

Coronary Artery Disease

United States, Italy, Spain, France, Korea, Republic of, Hungary, Japan, Argentina, China, India, Belgium, Switzerland, United Kingdom, Canada, Australia, Brazil, Chile, Ireland
Novartis Pharmaceuticals

Recruiting

A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines

Chronic Inducible Urticaria

China, United States, Australia, Korea, Republic of, Israel, Turkey, Hong Kong, Japan, Malaysia, Singapore, Argentina, Thailand, Canada
Celgene

Completed

A Phase 3, Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Pomalidomide in Combination With Low-Dose Dexamethasone Versus High-Dose Dexamethasone in Subjects With Refractory Multiple Myeloma or Relapsed and Refractory Multiple Myeloma and Companion Study (NIMBUS)

Multiple Myeloma

United States, Netherlands, Canada, Belgium, United Kingdom, Australia, Denmark, Germany, Spain, Switzerland, France, Italy, Greece, Russian Federation, Sweden, Czechia
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab (LIBERTY-CSU CUPID)

Chronic Spontaneous Urticaria

China, France, Spain, Argentina, Germany, Japan, United States, Canada, Hungary, Russian Federation, United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Efficacy of a Once-daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections (DFI) With a Substudy in Patients With Diabetic Foot Infections Complicated by Osteomyelitis.

Diabetic Foot | Bacterial Infections | Osteomyelitis

China, Colombia, Estonia, Denmark, Taiwan, France, United States, Canada, Spain, Belgium, Austria, Chile, Korea, Republic of, Mexico, Slovakia, United Kingdom, Russian Federation, Croatia, Turkey, Lithuania, Poland, Latvia, Finland, H... and more
Idorsia Pharmaceuticals Ltd.

Terminated

Clazosentan in Aneurysmal Subarachnoid Hemorrhage (CONSCIOUS-3)

Aneurysmal Subarachnoid Hemorrhage

United States, Belgium, Taiwan, Canada, Hong Kong, Singapore, Germany, Netherlands, India, Czechia, Switzerland, France, Australia, Spain, Denmark, Finland, Argentina, Brazil, Sweden, Austria, Chile, Hungary, Israel, Italy, Mexico, Norway, ... and more
Janssen Research & Development, LLC

Completed

A Study of the Safety and Efficacy of CNTO 328 and Bortezomib to Bortezomib Alone in Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, France, Poland, United Kingdom, Belgium, Spain, Germany, Portugal, Bulgaria, Romania, Netherlands, Greece, Canada, Russian Federation, Hungary, Brazil, Slovakia, Czechia
Janssen Research & Development, LLC

Approved for marketing

Early Access Treatment With Daratumumab for (Relapsed or Refractory) Multiple Myeloma

Multiple Myeloma

United States, United Kingdom, Spain, Brazil, Russian Federation, Japan
Celgene Corporation

Completed

A Study of Combination Thalidomide Plus Dexamethasone Therapy vs. Dexamethasone Therapy Alone in Previously Untreated Subjects With Multiple Myeloma

Multiple Myeloma

United States, Spain, Australia, Canada, United Kingdom, Italy, Switzerland, Bulgaria, Poland, Ukraine, Belgium, Germany, Hungary, Ireland, Israel, Russian Federation
Takeda

Completed

A Study of Oral Ixazomib Maintenance Therapy in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Not Treated With Stem Cell Transplantation (SCT)

Multiple Myeloma

France, Spain, United States, Taiwan, Korea, Republic of, Israel, Australia, Czechia, Hungary, Canada, Japan, Portugal, Singapore, United Kingdom, Italy, Sweden, Poland, Germany, China, Denmark, Greece, Thailand, Serbia, Turkey, Colombia, Russian Federation and more
University College Dublin
Universitaire Ziekenhuizen KU Leuven; National University of Ireland, Galway... and other collaborators

Active, not recruiting

Colchicine for Prevention of Vascular Inflammation in Non-cardio Embolic Stroke (CONVINCE)

Stroke | Ischemic Attack, Transient

Ireland, United Kingdom, Spain, Germany, Belgium, Denmark, Netherlands, Switzerland, Estonia, Canada, Portugal, Poland, Lithuania, Czechia
Hutchmed

Withdrawn

HMPL-760 Safety and Tolerability Study in Patients With Previously Treated CLL/SLL or NHL

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Lymphoplasmacytic Lymphoma | NHL | DLBCL | Richter Syndrome | CLL/SLL | MCL | MZL

United States, Spain, Australia, Israel, Italy, Poland, France
Janssen Research & Development, LLC

Completed

Addition of Daratumumab to Combination of Bortezomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, Australia, Poland, Ukraine, Germany, Spain, Turkey, Korea, Republic of, Brazil, Russian Federation, Netherlands, Hungary, Sweden, Czechia, Mexico
AstraZeneca

Completed

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS)

Myocardial Infarction | Stroke | Atherothrombosis | Cardiovascular Death

Sweden, United States, Australia, Brazil, Bulgaria, Czech Republic, France, Italy, Korea, Republic of, Peru, Poland, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Philippines, China, Hungary, Romania, U... and more
Janssen Research & Development, LLC
Harvard Medical School (HMS and HSDM); Bayer; Duke Clinical Research Institute

Completed

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome (GEMINI ACS 1)

Acute Coronary Syndrome

United States, France, Poland, Ukraine, Belgium, Spain, Argentina, Bulgaria, Russian Federation, Turkey, Japan, Canada, Netherlands, Korea, Republic of, Brazil, Australia, Hungary, Sweden, Czechia, Denmark
InflaRx GmbH
Iqvia Pty Ltd

Terminated

Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA

Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA)

United States, Canada
Novo Nordisk A/S

Completed

A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients With Severe Haemophilia A (pathfinder™5)

Congenital Bleeding Disorder | Haemophilia A

France, United States, Switzerland, Malaysia, Brazil, Canada, Japan, United Kingdom, Israel, Portugal, Ukraine, Greece, Lithuania, Puerto Rico, Turkey, Italy
Henry Ford Health System
Chiesi Farmaceutici S.p.A.; Abiomed Inc.

Completed

National Cardiogenic Shock Initiative (NCSI)

Acute Myocardial Infarction | Cardiogenic Shock | NSTEMI - Non-ST Segment Elevation MI | Heart Attack | STEMI - ST Elevation Myocardial Infarction

United States
Celgene

Completed

Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma

Lymphoma | Lymphoma, Large B-Cell, Diffuse | Glioblastoma | Multiple Myeloma | Primary Central Nervous System Lymphoma | Pleiotropic Pathway Modifier

United States, Spain, Belgium, France, Italy
Astellas Pharma Inc

Completed

A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease

Coronary Artery Disease | Pulmonary Disease, Chronic Obstructive | Asthma

United States
Novartis Pharmaceuticals

Completed

A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1 Antihistamines (REMIX-1)

Chronic Spontaneous Urticaria

United States, Hungary, Taiwan, Spain, Italy, Korea, Republic of, Australia, France, Bulgaria, Czechia, Turkey, India, Argentina, Mexico, Japan, Colombia, Russian Federation, Puerto Rico, Singapore
Janssen Research & Development, LLC

Recruiting

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment (MonumenTAL-3)

Relapsed or Refractory Multiple Myeloma

United States, Italy, Korea, Republic of, Taiwan, China, Germany, Turkey, Japan, France, United Kingdom, Brazil, Spain, Czechia, Poland, Israel, Belgium, Greece, Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease (MODIFY)

Fabry Disease

United States, Spain, Belgium, Australia, Austria, Canada, Germany, Ireland, Italy, Netherlands, Norway, Poland, Switzerland, United Kingdom
Bayer
Population Health Research Institute

Completed

Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain. (PACIFIC-STROKE)

Acute Non-cardioembolic Ischemic Stroke

Spain, Japan, Australia, Czechia, Sweden, United Kingdom, Netherlands, Belgium, Russian Federation, Hungary, Slovakia, China, Germany, Switzerland, France, Poland, Denmark, United States, Austria, Bulgaria, Finland, Italy, Portugal
Heart Care Foundation
AstraZeneca; Centro Servizi ANMCO S.r.l.

Completed

EYESHOT (EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian Coronary Care Units) (EYESHOT)

Acute Coronary Syndromes

Italy
Celgene

Not yet recruiting

A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (ALUMMINATE)

Multiple Myeloma

China, Australia, United States, Argentina, Austria, Belgium, Brazil, Canada, Chile, Czechia, France, Germany, Greece, Hungary, India, Ireland, Italy, Japan, Korea, Republic of, Norway, Portugal, Romania, Spain, Sweden, Switzerland, Turkey, United Kingdom
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

Brain and Central Nervous System Tumors

United States, Canada
Novartis Pharmaceuticals

Completed

A Multiple Myeloma Trial in Patients With Bone Metastases

Multiple Myeloma

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study of PS-341 Given to Patients With Multiple Myeloma Who Experienced Progressive Disease After Receiving Dexamethasone in M34101-039

Multiple Myeloma

United States, United Kingdom, Canada, Israel, France, Austria, Belgium, Germany, Ireland, Italy, Netherlands, Spain, Sweden
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication

Type 2 Diabetes

Australia, United States, Canada, Mexico, Puerto Rico, Germany, Hungary, Ireland, Poland, Romania, Denmark, Czech Republic, India, Colombia, Finland, United Kingdom
Rutgers, The State University of New Jersey
National Heart, Lung, and Blood Institute (NHLBI); University of Pittsburgh

Completed

Myocardial Ischemia and Transfusion (MINT)

Myocardial Infarction | Anemia

New Zealand, United States, France, Canada, Australia, Brazil
Gilead Sciences

Completed

Efficacy and Safety Study of Idelalisib in Participants With Indolent B-Cell Non-Hodgkin Lymphomas (DELTA)

Follicular Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Small Lymphocytic Lymphoma

United States, United Kingdom, Italy, Germany, Poland, France
Abbott Medical Devices
Cardiovascular Research Foundation, New York

Active, not recruiting

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial (ECLIPSE)

Coronary Artery Disease | Ischemic Heart Disease | Non ST Segment Elevation Myocardial Infarction

United States
Novo Nordisk A/S

Completed

Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Previously Untreated Patients With Haemophilia A (pathfinder™6)

Congenital Bleeding Disorder | Haemophilia A

United States, Spain, Australia, France, Thailand, Italy, Malaysia, Austria, Greece, Japan, Taiwan, Canada, Israel, Algeria, Argentina, Bulgaria, Germany, Romania
Janssen Research & Development, LLC

Active, not recruiting

A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant (AURIGA)

Multiple Myeloma

United States, Canada
Janssen Research & Development, LLC

Active, not recruiting

A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

Multiple Myeloma

Canada, United States, Israel, Czechia, Turkey, Germany, United Kingdom, Japan, Netherlands, France, Brazil, Poland, Spain
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant

Lymphoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
Takeda

Active, not recruiting

A Study of Modakafusp Alfa on Adult Participants With Relapsed/Refractory Multiple Myeloma (iinnovate-1)

Multiple Myeloma

United States, Spain, Canada, Korea, Republic of, Taiwan, China, Italy, Germany, Israel, France, United Kingdom, Greece, Japan, Norway, Puerto Rico, Turkey
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma

DS Stage I Multiple Myeloma | DS Stage II Multiple Myeloma | DS Stage III Multiple Myeloma

United States, Saudi Arabia, Puerto Rico
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes and Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker

Type 2 Diabetes

Mexico, Russian Federation, Spain, United States, Canada, Puerto Rico, Hungary, Peru, Romania, Poland, Germany, Czech Republic, India, Colombia, Denmark, Finland
Human Genome Sciences Inc., a GSK Company
GlaxoSmithKline

Completed

Belimumab in Remission of VASculitis (BREVAS)

Vasculitis

United States, Australia, France, Spain, Italy, Peru, Belgium, Canada, Germany, Romania, Mexico, United Kingdom, Hungary, Ireland, Poland, Switzerland, Czechia, Russian Federation, Norway, Sweden
Axio Research. LLC
National Heart, Lung, and Blood Institute (NHLBI); Abbott

Terminated

Niacin Plus Statin to Prevent Vascular Events

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis | Cerebrovascular Accident

United States, Canada
Bristol-Myers Squibb

Recruiting

Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)

Multiple Myeloma

United States, Canada, France, Germany, Italy, United Kingdom
Pfizer

Completed

Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers

Diabetes Complications | Foot Ulcer, Diabetic

United States
Giselle Sholler
Translational Genomics Research Institute; Dell, Inc.

Completed

Molecular-Guided Therapy for Childhood Cancer

Glioma | Renal Cell Carcinoma | Osteosarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Meningioma | Craniopharyngioma | Choroid Plexus Neoplasms | Rhabdomyosarcoma | Wilms Tumor | Ewings Sarcoma | Malignant Rhabdoid Tumor | Liver Tumors | Germ Cell Tumors | Dysembryoplastic Neuroepithelial Tumor | Clear Cell Sarcoma | ... and other conditions

United States, Lebanon

Clinical Trials on Wet Macular Degeneration in South Africa

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