Clinical Trials on de Novo Lesions in Native Coronary Arteries

Total 159 results

Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
Medinol Ltd.

Completed

NIRTRAKS Post-Market Study (NIRTRAKS) (NIRTRAKS)

de Novo Stenotic Lesions in Native Coronary Arteries

United States
Abbott Medical Devices
Baim Institute for Clinical Research

Withdrawn

Comparative Study Of Safety And Efficacy Of The SUPERA® Nitinol Stent - Iliac Artery (I-WIN)

With de Novo or Restenotic Lesions in the Common and/or External Iliac Arteries
Biotronik AG

Completed

Long Term Safety Profile of the PRO-Kinetic ENERGY Coronary Stent System in Daily Clinical Practice (ENERGY)

De Novo and Re-stenosed Coronary Artery Lesions

Switzerland, Netherlands, Israel, Spain, Latvia, Germany, Austria, Belgium, France, Ireland
Tryton Medical, Inc.

Completed

Prospective, Single Blind, Rand Controlled Study to Evaluate the Safety & Effectness of Tryton Side Branch Stent Used With DES Treatmt of de Novo Bifurcation Lesions in MB & SB in Native Coronaries (TRYTON)

Coronary Atherosclerosis of Native Coronary Artery | Bifurcation Lesions: de Novo Lesions of the Main and Side Branch of Native Coronary Artery

United States
Boston Scientific Corporation

Completed

TAXUS ARRIVE 2: A Multi-Center Safety Surveillance Program (ARRIVE 2)

Cardiovascular Disease | de Novo Coronary Lesions

United States
Tel-Aviv Sourasky Medical Center

Completed

CRE8 in All Comers Patients

Consecutive Subjects Who Are Suitable for a Coronary | Angioplasty of de Novo Lesion(s) in Native Coronary | Arteries Should be Screened for Eligibility. | A Total Number of 200 Patients Fulfilling the Selection | Criteria and Willing to Sign the Informed Consent Should | be Enrolled in the...

Israel
Shenzhen People's Hospital

Not yet recruiting

Resting Full-cycle Ratio-guided Step by Step Balloon Dilation (REDUCE)

de Novo Coronary Lesions
S.M. Misericordia Hospital

Completed

Prospective Study to Assess DES Re-endothelization in BMS Restenosis and De-novo Lesions (DESERT)

Stable Coronary Artery Disease | Silent Myocardial Ischemia | In-stent(BMS)Restenosis | De-novo, Atherosclerotic, Coronary Lesions

Italy
Biosensors Europe SA

Completed

BioFreedom FIM Clinical Trial.

Treatment Of Stenotic Lesions In Native Coronary Arteries.

Germany
Medinol Ltd.

Completed

MedJ-01 Ridaforolimus Eluting Coronary Stent System Trial (JNIR) (JNIR)

de Novo or Restenosis Lesions

Japan
Advanced MedTech Solutions Pvt. Ltd.

Not yet recruiting

Advapro Coronary Stent System in Coronary Artery Diseased Patients. (RESTORE)

Coronary Artery Disease | Coronary Stent Implantation | De Novo Stenosis Lesion
Novartis Pharmaceuticals

Completed

Comparison of a Tacrolimus Hexal® Based Regimen Versus a Prograf® Based Regimen in de Novo Renal Transplant Recipients (Spartacus)

Pharmacokinetics Study in de Novo Kidney Transplantation

Germany
Xijing Hospital

Active, not recruiting

Paclitaxel-coated Balloon for Treatment of De-novo Non-complex Coronary Artery Lesions

Coronary Artery Disease | De Novo Stenosis

China
Xijing Hospital

Active, not recruiting

Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions (CAGE-FREEIII)

Coronary Artery Disease | Percutaneous Coronary Intervention | De Novo Stenosis

China
Yinyi(Liaoning) Biotech Co., Ltd.

Completed

Bingo Drug-Coated Balloon in Real World

Coronary Stenosis | De Novo Stenosis | Drug-coated Balloon | Coronary Artery Disease in Transplanted Heart Accelerated

China
University Hospital, Saarland

Terminated

Efficacy of the SeQuent®Please in the Treatment of De-novo Stenoses Versus Taxus™Liberté™ (PEPCAD-DEBonly)

Coronary De-novo Stenoses

Germany
General Administration of Military Health, Tunisia
B. Braun Medical International Trading Company Ltd.

Recruiting

Drug Eluting Balloon Angioplasty Versus Everolimus Platinum Chrome Stent (DEBATE)

Coronary Artery Disease (CAD) | De Novo Stenosis | Percutaneous Coronary Intervention (PCI)

Tunisia
Rede Optimus Hospitalar SA

Recruiting

Shockwave IVL + DCB

Calcified Lesions in Small Coronary Vessels

Italy, Brazil
Biotronik AG

Terminated

BIOFLOW-SV All Comers Registry (BIOFLOW-SV)

Restenoses, Coronary | de Novo | Symptomatic Ischemic Heart Disease

Brazil
Korea University Ansan Hospital
B. Braun Korea Co., Ltd.

Recruiting

STabilization of Atheroma By Lipid-reducing Effect of Drug-Coated Balloon (STABLE-DCB) (STABLE-DCB)

Coronary Artery Disease | De Novo Stenosis | Atherosclerotic Plaque

Korea, Republic of
Sydney South West Area Health Service

Unknown

IVUS Controlled Stenting

Coronary Angioplasty and Stenting | Single de Novo Coronary Artery Stenoses

Australia
Harbin Medical University
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Active, not recruiting

Safety and Efficacy of Drug-Coated Balloon for De-novo Lesions in Patients With Acute Coronary Syndromes (DCB-ACS) (DCB-ACS)

Coronary Artery Disease | De Novo Stenosis | Clinical Trial | Acute Coronary Syndromes | ACS | DCB | Drug-Coated Balloon

China
B. Braun Medical Industries Sdn. Bhd.
Seoul National University Hospital; Ulsan University Hospital; European Cardiovascular... and other collaborators

Recruiting

Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease (REVERSE)

Myocardial Ischemia | Coronary Artery Disease | Acute Coronary Syndrome | Coronary Stenosis | De Novo Stenosis

Malaysia, Taiwan, Korea, Republic of, Singapore
Xijing Hospital

Recruiting

Intravascular Lithotripsy Versus Conventional Therapy for Severely Calcified Coronary Artery Lesions (REC-CHIPCAC)

De Novo Stenosis | Severely Calcified Coronary Stenoses

China
Zunyi Medical College

Recruiting

Joint Inflation With Nominal-pressure and Stability Approach in DES Optimization

Acute Coronary Syndrome | De Novo Stenosis

China
Genoss Co., Ltd.

Completed

Compare the Efficacy and Safety of Genoss® DCB and IN.PACT Admiral® DCB in Patients With Peripheral Artery Disease

Peripheral Artery Disease | De Novo Stenosis

Korea, Republic of
Essen Technology (Beijing) Co., Ltd.

Unknown

Evaluate Safety And Effectiveness Of The Tivoli® DES and The Firebird2® DES For Treatment Coronary Revascularization

Myocardial Ischemia | Coronary Disease | Acute Coronary Syndrome | Ischemic Heart Disease | Coronary Artery Lesions,Primary | Furcation Lesion of Coronary Artery

China
J.J. Wykrzykowska
Abbott Medical Devices

Unknown

Bifurcation ABSORB OCT Trial (BISORB OCT)

Myocardial Infarction | Infarction | Ischemia | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Arteriosclerosis | Coronary Bifurcation Lesions | Arterial Occlusive Lesions

Netherlands
AstraZeneca

Completed

Exploratory Study of Coronary Flow Reserve Measurements, a Non-Invasive Method for Coronary Function Measurements

Atherosclerosis | Inflammatory Activity in Coronary Arteries

Sweden
Minneapolis Heart Institute Foundation

Recruiting

Progress Bifurcation Global Registry

Coronary Artery Disease | Coronary Bifurcation Lesions

United States
University of Patras

Unknown

Transradial Versus Transulnar Artery Approach for Coronary Interventions (AURA)

Arterial Access in Percutaneous Coronary Angiography or Intervention

Greece
Johns Hopkins University

Recruiting

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography] (PET; CT)

Coronary Artery Disease | Atherosclerosis | Coronary Atherosclerosis of Native Coronary Artery

United States
Samara State Medical University
Regional Samara Clinical Hospital n. a. V.D.Seredavin

Recruiting

Cardiovascular Risk Stratification on the Basis of Surface Enhanced Raman Spectroscopy (CRUISERS)

Coronary Atherosclerosis of Native Coronary Artery

Russian Federation
Ospedale Santa Maria Goretti

Withdrawn

Efficacy Study of Kissing Drug-Eluting Balloons in Coronary Bifurcation Lesions (KISSING DEBBIE)

Coronary Artery Disease | Bifurcation Lesions

Italy
Xuzhou Third People's Hospital

Unknown

Clinical Efficacy and Safety of a Prospective, Multicenter Drug Coated Balloon for Left Main Artery Disease in China

Left Main Coronary Artery Disease | Bifurcation Lesions | Coronary Diseases

China
Fondazione Evidence per Attività e Ricerche Cardiovascolari...

Not yet recruiting

SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective (SPAGO)

Coronary Artery Disease | Percutaneous Coronary Intervention | Coronary Artery Lesion | Stenosis Coronary
Cathreine BV
Catharina Ziekenhuis Eindhoven; St. Antonius Hospital; Medical Centre Leeuwarden and other collaborators

Recruiting

Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy (Hybrid DEB)

Coronary Artery Disease | Coronary Bifurcation Lesion

Netherlands
Elixir Medical Corporation
Istituto Clinico Humanitas

Active, not recruiting

DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions (DYNAMITE)

Coronary Artery Disease | Chronic Total Occlusion of Coronary Artery | Multi Vessel Coronary Artery Disease | Bifurcation of Coronary Artery | Long Lesions Coronary Artery Disease

Italy
Segeberger Kliniken GmbH

Completed

The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC) (PREPARE-CALC)

Coronary Atherosclerosis Due to Severely Calcified Coronary Lesion

Germany
Biotronik (Beijing) Medical Device Ltd.
Biotronik AG

Enrolling by invitation

BIOFLOW-china Post-marketing Study (BIOTRONIK)

Native Coronary Artery Stenosis | In-Stent Stenosis (Restenosis) of Coronary Artery Stent

China
Xuzhou Third People's Hospital

Not yet recruiting

Yao Strategy for the Treatment of de Novo Medina 0,1,0 or 0,0,1 Bifurcation Lesion

Coronary Artery Disease | Bifurcation Lesion
Concept Medical Inc.
Cardiovascular Research Foundation, New York

Not yet recruiting

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels (MAGICAL-SV)

Cardiovascular Diseases | Coronary Artery Disease | Native Coronary Artery Stenosis
Samsung Medical Center

Not yet recruiting

Routine Versus As-Needed Stress Testing in Asymptomatic Patients With High-Risk Coronary Calcium (SMART-EXAM)

Coronary Atherosclerosis Due to Calcified Coronary Lesion
Scitech Produtos Medicos Ltda

Unknown

INSPIRON Sirolimus Eluting Stent Performance in Bifurcation Coronary Arteries Treated Using Provisional Technique (insProvisional)

Coronary Artery Disease | Bifurcation Lesion

Brazil
Increase Co., Ltd.
Erasmus Medical Center; Terumo Corporation; Fujita Health University

Unknown

Using 3D Imaging to Optimize Bifurcation Stenting

Coronary Artery Disease | Bifurcation Lesion

Japan, Netherlands
Abbott Medical Devices

Recruiting

Abbott Vascular Medical Device Registry (AV-MDR)

Acute Myocardial Infarction | Restenoses, Coronary | Coronary Artery Lesions | Venous Embolism | Arterial Embolism

United States, China, Hungary, Spain, Germany, Austria, Australia, Belgium, France, Italy, Netherlands, Switzerland, Taiwan, United Arab Emirates
Zhejiang Hisun Pharmaceutical Co. Ltd.

Completed

Efficacy and Safety Study of the HS-25 Combination With Atorvastatin in Subjects With Hypercholesterolemia in Coronary Heart Diseases (HS-25-III-02)

Hypercholesterolemia in Coronaory Heart Disease
Clinica Mediterranea

Completed

The XLIMUS-DES in Very Complex Lesions

Chronic Total Occlusion of Coronary Artery | Coronary Atherosclerosis Due to Calcified Coronary Lesion

Italy
Maimónides Biomedical Research Institute of Córdoba

Active, not recruiting

Usefulness of the Use of Co-registration Strategy With iFR in Long and/or Diffuse Coronary Lesions (iLARDI)

Instantaneous Wave Free Ratio | Diffuse Coronary Artery Disease | Long Coronary Lesion | Syncvision Software

Spain

Clinical Trials on de Novo Lesions in Native Coronary Arteries

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