Clinical Trials on mTOR Pathway Abberation

Total 2069 results

M.D. Anderson Cancer Center

Recruiting

Early Assessment of Ovarian Cancer Aggressiveness by Metabolic Imaging

Ovarian Cancer

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Research Motor... and other collaborators

Recruiting

Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis (MotorMarker)

ALS (Amyotrophic Lateral Sclerosis) | Postpoliomyelitis Syndrome | Spinal Muscular Atrophy

Ireland
University Hospital, Clermont-Ferrand

Active, not recruiting

Fall Risk Assessment in a Population of Charcot-Marie-Tooth Disease Type 1A (CMT 1A) by Timed Up and Go Test (DeteCTCMT)

Charcot-Marie-Tooth Type 1A Neuropathy

France
Children's Hospital Medical Center, Cincinnati

Completed

Flu Vaccine Study in Neuromuscular Patients 2011

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy | Congenital Muscular Dystrophy
Assistance Publique - Hôpitaux de Paris

Terminated

Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders (Nemucough)

Neuromuscular Diseases | Amyotrophic Lateral Sclerosis | Duchenne Muscular Dystrophy

France
University Health Network, Toronto
University of Florida; National Institute on Deafness and Other Communication...

Completed

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

Parkinson Disease | Amyotrophic Lateral Sclerosis | Dysphagia

United States
University Hospital, Clermont-Ferrand

Completed

Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1A (CCA1)

Charcot-Marie-Tooth Type 1A Neuropathy

France
Istituto Ortopedico Rizzoli

Completed

Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial.

Entrapment Neuropathy, Carpal Tunnel | Compression Neuropathy, Carpal Tunnel | Median Neuropathy, Carpal Tunnel

Italy
University of Texas at Austin
Hospital Clinic of Barcelona; Fundació Institut de Recerca de l'Hospital de...

Recruiting

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Language Disorders | Communication Disorders | Primary Progressive Aphasia | Aphasia | Speech Disorders | Frontotemporal Lobar Degeneration | Dysarthria | Apraxia, Motor | Dementia, Frontotemporal | Bilingual Aphasia

Spain, United States
Zarife Sahenk

Recruiting

NT-3 Levels and Function in Individuals With CMT

Charcot-Marie-Tooth Disease | Peripheral Neuropathy | Chronic Inflammatory Demyelinating Polyneuropathy

United States
Grand Valley State University

Active, not recruiting

Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

Cerebral Palsy | Spinal Cord Injuries | Spinal Muscular Atrophy | Genetic Disease | Spina Bifida | Development Delay

United States
Powell Mansfield Inc.

Completed

Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx

Healthy | Amyotrophic Lateral Sclerosis | Obstructive Sleep Apnea | Muscular Dystrophies

United States
University Hospital, Clermont-Ferrand

Completed

Diffusion Tensor Imaging in Chronic Inflammatory Demyelinating Polyneuropathy (PIDC) (PIDC)

CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) | CMT (Charcot Marie Tooth Disease)

France
Universität Duisburg-Essen
Weinmann Geräte für Medizin GmbH + Co. KG

Completed

Optimum Insufflation Capacity in NMD

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy | Chronic Respiratory Insufficiency

Germany
Medipol University

Recruiting

The Effect of Spinal Orthosis on the Development of Scoliosis and Chest Deformity in Type I Spinal Muscular Atrophy

Scoliosis | Exercise | Pulmonary Rehabilitation | Spinal Muscular Atrophy Type I | Chest Deformities | Spinal Orthosis

Turkey
University of Miami Sylvester Comprehensive Cancer...
The V Foundation for Cancer Research

Recruiting

With Love, Grandma ("Con Cariño, Abuelita") Pilot Study

Obesity | Diet, Healthy | Cancer, Breast | Activity, Motor | Cancer, Uterus | Cancer, Ovary

United States
Assistance Publique - Hôpitaux de Paris

Completed

Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor (Es-Alert)

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy

France
National Institute of Mental Health (NIMH)

Terminated

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

HIV Infections | Healthy | AIDS Dementia Complex | AIDS-Related Dementia Complex | HIV-Associated Cognitive Motor Complex | HIV-Dementia | AIDS Encephalopathy

United States
University College, London
University of Iowa

Unknown

Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort Study

Charcot-Marie-Tooth Disease, Type IA | Charcot-Marie-Tooth Disease Type 2A | Charcot-Marie-Tooth Disease, Type IB | Charcot-Marie-Tooth Disease, Type X

United Kingdom
Istituto Auxologico Italiano

Recruiting

Advances in Telephone-based Cognitive Screening Procedures (TBCS)

Cerebrovascular Disorders | Amyotrophic Lateral Sclerosis | Frontotemporal Degeneration | Alzheimer's Disease | Lewy Body Dementia

Italy
Mayo Clinic

Terminated

Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder

Sleep Disorder | Restless Legs Syndrome | Iron-deficiency | Periodic Limb Movement Sleep Disorder

United States
University of Alabama at Birmingham
National Institute of Nursing Research (NINR)

Completed

Individualized Cognitive Training in HIV (TOPS)

Cognitive Impairment | Aging | Cognitive Decline | Attention Impaired | Cognitive Deficit in Attention | HIV-Associated Cognitive Motor Complex | Processing, Visual Spatial | Cognitive Disorder in Remission

United States
Assistance Publique - Hôpitaux de Paris
Centre National de la Recherche Scientifique, France

Completed

Acoustic and Perceptual Markers of Dysarthria in Amyotrophic Lateral Sclerosis (ALS) (SPEECH-ALS)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Kennedy's Disease

France
Nantes University Hospital
Université de Nantes

Unknown

Quantification of Nerve Stiffness in Neuropathies (Nerf_SSI)

Chronic Inflammatory Demyelinating Polyneuropathy | Anti-MAG Neuropathy | Charcot-Marie-Tooth Disease, Type IA

France
Skane University Hospital

Completed

Nerve Morphology in Diabetic Patients

Diabetes Complications | Carpal Tunnel Syndrome | Peripheral Neuropathy | Entrapment Neuropathies

Sweden
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease

Amyotrophic Lateral Sclerosis | Spinal Muscular Atrophy | Spinobulbar Muscular Atrophy
National Cancer Institute (NCI)

Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
Laurent Servais
SYSNAV

Recruiting

Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study

Duchenne Muscular Dystrophy | Myotonic Dystrophy 1 | Congenital Muscular Dystrophy | Centronuclear Myopathy | Charcot-Marie-Tooth | Fascioscapulohumeral Muscular Dystrophy

Belgium
Novartis Pharmaceuticals

Available

Managed Access Programs for PKC412, Midostaurin

Acute Myeloid Leukemia | Mast Cell Leukemia | Aggressive Systemic Mastocytosis | Systemic Mastocytosis With an Associated Hematologic Neoplasm | FMS-Like Tyrosine Kinase 3 (FLT3)-Mutated Acute Myeloid Leukemia
AbiliTech Medical Inc.
Richard M. Schulze Family Foundation

Recruiting

Schulze Muscular Dystrophy Ability Clinical Study

Cerebral Palsy | Muscular Dystrophies | Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Spinal Muscular Atrophy | Limb Girdle Muscular Dystrophy | FSHD

United States
Hospices Civils de Lyon

Recruiting

Control Cohort CTRL COH (CTRL COH)

Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Disease; Rheumatoid Polyarthritis

France
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

EEG and TMS-based Biomarkers of ALS, MS and FTD

Multiple Sclerosis | Amyotrophic Lateral Sclerosis | Frontotemporal Dementia

Ireland
University of Alabama at Birmingham

Recruiting

AIM's Writing for Healing: A Workshop for Individuals Living With Paralysis

Multiple Sclerosis | Amyotrophic Lateral Sclerosis | Spinal Cord Injuries | Transverse Myelitis

United States
University of Miami
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes... and other collaborators

Recruiting

Clinical Procedures to Support Research in ALS (CAPTURE-ALS)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy | ALS-Frontotemporal Dementia

United States
Neuromed IRCCS
IRCCS Multimedica

Recruiting

Biomarkers of Synaptic Damage in Multiple Sclerosis

Multiple Sclerosis | Parkinson Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease

Italy
October 6 University

Completed

Effect of Chitosan Phonophoresis On Cubital Tunnel Syndrome

Cubital Tunnel Syndrome | Ulnar Nerve Entrapment at Elbow | Ulnar Nerve Compression | Ulnar Nerve Entrapment Syndrome

Egypt
Clionsky Neuro Systems Inc.

Completed

Concussion in Motor Vehicle Accidents: The Concussion Identification Index (CIDI)

Brain Injuries | TBI (Traumatic Brain Injury) | Motor Vehicle Accidents | Brain Concussion | Brain Contusion | Traumatic Brain Injury With Brief Loss of Consciousness | Cerebral Concussion | Accidents, Traffic | Traumatic Brain Injury With Loss of Consciousness | Traffic Accidents | Cortical Contusion | Concussion... and other conditions

United States
University of Miami
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Active, not recruiting

TRIAL READY (Clinical Trial Readiness)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Dementia | Progressive Muscular Atrophy | ALS-Frontotemporal Dementia

United States
University of Alberta

Withdrawn

Digital Smartwatch Measurements as Potential Biomarkers for Remote Disease Tracking in ALS

Healthy | Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Dementia | Muscular Atrophy, Progressive

Canada
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
Sahlgrenska University Hospital, Sweden

Completed

10 Years Follow-up Study of Plantar Pressure, Kinetics and Kinematics in a Cohort of Patients Diagnosed With Diabetes (Diab10)

Diabetes | Diabetic Foot | Foot Ulcer | Foot Deformities | Neuropathy | Gait Disorder, Sensorimotor | Plantar Ulcer | Motor Neuropathy

Sweden
Massachusetts General Hospital
ALS Association

Completed

Electronic-health Application To Measure Outcomes REmotely Clinical Trial (EAT MORE)

Parkinson's Disease | Amyotrophic Lateral Sclerosis | Weight Loss | Cachexia | Huntington's Disease | Neurodegenerative Disease

United States
University of Rhode Island
National Institute of Nursing Research (NINR); Thrasher Research Fund

Completed

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Necrotizing Enterocolitis | Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Motor Skills Disorders | Late Onset Neonatal Sepsis

United States
Skane University Hospital

Completed

Nerve Entrapment in Diabetic Patients

Diabetes Complications | Carpal Tunnel Syndrome | Nerve Compression Syndromes | Entrapment Neuropathies

Sweden
University of California, San Diego
New York University; Heinrich-Heine University, Duesseldorf; Universität Tübingen

Recruiting

Natural History Study of Patients With HPDL Mutations

Genetic Disease | Mitochondrial Encephalomyopathies | Neonatal Encephalopathy | Mutation | Hereditary Spastic Paraplegia | White Matter Disease | Spastic Paraplegia

United States
St. Olavs Hospital
Norwegian University of Science and Technology; The Research Council of Norway and other collaborators

Recruiting

Early Psychological Intervention After Rape (EIR)

Sexual Dysfunctions, Psychological | Sleep Disturbance | Post Traumatic Stress Disorder | Depression, Anxiety | Activity, Motor | Pelvic Pain Syndrome | Rape Sexual Assault | Pelvic Floor Myalgia | Cortisol Deficiency

Norway
National Institute of Neurological Disorders and...

Recruiting

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Amyotrophic Lateral Sclerosis | Frontotemporal Dementia | Progressive Supranuclear Palsy

United States
Ontario Neurodegeneration Disease Research Initiative

Completed

The Ontario Neurodegenerative Disease Research Initiative (ONDRI)

Stroke | Parkinson Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease | Frontotemporal Dementia

Canada

Clinical Trials on mTOR Pathway Abberation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in New Zealand

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Rare Diseases

Drug Interventions

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