Search clinical trials for: α-globin restored autologous hematopoietic stem cells

Total 1254 results

Joanne Kurtzberg, MD
M.D. Anderson Cancer Center; Emory University; The Marcus Foundation

Completed

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke (CoBIS 2)

Stroke | Stroke, Acute | Brain Injury, Acute

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States
Kiadis Pharma

Completed

Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

Canada, Belgium, Germany, Croatia, United Kingdom, Portugal
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Wenzhou Medical University

Unknown

Autologous Bone Marrow Stem Cells Infusion for the Treatment of Liver Diseases. (ABMSCIFTLD)

Liver Diseases

China
National Cancer Institute (NCI)

Completed

Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer

Renal Cell Carcinoma | Graft-Versus-Host Disease | Engraftment Syndrome

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Effect of Mesenchymal Stem Cells in Primary Knee Osteoarthritis

Osteoarthritis Knee

Bangladesh
Chinese University of Hong Kong

Completed

RCT Mesenchymal Stem Cells Versus Hyaluronic Acid in OA Knee): (MSC)

Osteoarthritis, Knee

Hong Kong
University Health Network, Toronto

Recruiting

Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis (ALLO-BAT)

Myelofibrosis | Bone Marrow Cancer | High-Risk Cancer

Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma

Ewing Sarcoma of Bone | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) and other conditions

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Autologous Stem Cell Transplant in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

Lymphoma

United States
University of Southampton
NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation... and other collaborators

Terminated

High-Dose Melphalan With or Without Radiolabeled Monoclonal Antibody in Treating Patients With Multiple Myeloma Undergoing an Autologous Stem Cell Transplant (AntiCD-66)

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Sichuan University

Unknown

Chidamide Combined With Clad/Gem/Bu With AutoSCT in High Risk Hodgkin & Non-Hodgkin Lymphoma

Hodgkin Lymphoma | Non-hodgkin Lymphoma
Boston Medical Center

Terminated

2nd Autologous Stem Cell Transplant in Patients With Persistent/Recurrent (AL) Amyloidosis

Multiple Myeloma | Plasma Cell Neoplasm

United States
University of Oxford
Mahidol University; Worldwide Antimalarial Resistance Network

Completed

Tracking Resistance to Artemisinin (TRAC) (TRAC)

Falciparum Malaria

Kenya, Thailand, Cambodia, Bangladesh, Congo, The Democratic Republic of the, India, Lao People's Democratic Republic, Myanmar, Nigeria, Vietnam
H. Lee Moffitt Cancer Center and Research Institute

Completed

Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT)

Multiple Myeloma

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
KLSMC Stem Cells, Inc.

Completed

Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee

Articular Cartilage Disorder of Knee | Articular Cartilage; Degeneration

United States, Malaysia
National Institutes of Health Clinical Center (CC)

Completed

Plasmapheresis of Anthrax-Vaccinated Subjects for Production of Anthrax Immune Globulin

Anthrax

United States
The First Affiliated Hospital of Soochow University

Recruiting

GVHD Prophylaxis by Addition of CD20 Monoclonal Antibody to the Conditioning Regimen in SAA With Treatment of Allo-HSCT

Aplastic Anemia

China
Memorial Sloan Kettering Cancer Center

Terminated

Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

Acute Leukemia | Myelodysplastic Syndrome | Non-Hodgkins Lymphoma | Chronic Leukemia

United States
TriStar Health

Withdrawn

Pilot Study of Stem Cell Transplantation for Children and Young Adults With Refractory Crohn's Disease.

Crohn's Disease
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604)

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Leukemia, Myeloid, Acute | Burkitt Lymphoma | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

United States
Medicines for Malaria Venture
Shin Poong Pharmaceuticals; Institute of Tropical Medicine, University of Tuebingen

Completed

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria

Gabon
Duke University
National Institutes of Health (NIH)

Completed

Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection (Bacteremia)

Bacteremia

United States, Spain
Colorado Blood Cancer Institute

Unknown

Fludarabine and 400 CGY Total Body Irradiation for Recipients of HLA-Matched or Mis-Matched Family or Unrelated Donor Hematopoietic Stem Cell Transplants Who Have Rejected Their First Allogeneic Stem Cell Transplant

Graft Failure

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior

Acute Myeloid Leukemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Stem Cell Transplant to Treat Patients With Favorable or Intermediate Risk Minimal Residual Disease Negative Acute Myeloid Leukemia

Acute Myeloid Leukemia | Minimal Residual Disease Negativity

United States
University of Wisconsin, Madison

Completed

TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma

Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Allogeneic Hematopoietic Stem Cell Transplantation Recipient

United States
Wuerzburg University Hospital
Celgene Corporation; ClinAssess GmbH

Active, not recruiting

Lenalidomide, Adriamycin, Dexamethasone (RAD) Versus Lenalidomide, Bortezomib, Dexamethasone (VRD) for Induction in Newly Diagnosed Multiple Myeloma Followed by Response-adapted Consolidation and Lenalidomide Maintenance

Previously Untreated Symptomatic Multiple Myeloma

Germany
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

United States
Gesellschaft fur Medizinische Innovation - Hamatologie...
Celgene; Amgen

Terminated

Therapy of Non-Hodgkin-Lymphoma by Combination of Lenalidomide + Rituximab, Dexa, High-dose ARA-C and CisP (R²-DHAP)

Diffuse Large B-cell Lymphoma (DLBCL) | Burkitt Lymphoma (BL) | Follicular Lymphoma Grade III (FL III°) | Mantle Cell Lymphoma (MCL), Blastoid Variant | Aggressive Marginal Zone Lymphoma (MZL)

Germany
St. Jude Children's Research Hospital

Completed

Haploidentical Hematopoietic Stem Cell Transplantation Patients With Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome

United States
University College, London
Amgen

Active, not recruiting

Carfilzomib/Cyclophosphamide/Dexamethasone With Maintenance Carfilzomib in Multiple Myeloma (Cardamon)

Multiple Myeloma

United Kingdom
University of Magdeburg

Unknown

Risk Adapted Therapy Optimization for Patients With Relapsed or Refractory Aggressive Non-Hodgkin-Lymphoma

Non-Hodgkin's Lymphoma

Germany
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Total-Body Irradiation Followed By Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

Lymphoma

United States
European Society for Blood and Marrow Transplantation
EULAR

Withdrawn

Autologous Stem Cell Transplantation: International Lupus Trial (ASTIL)

REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS

France
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Yttrium Y 90 Basiliximab and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Mature T-cell Non-Hodgkin Lymphoma

Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma | Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma | Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

BEAM vs. 90-Yttrium Ibritumomab Tiuxetan (Zevalin®)/BEAM With ASCT for Relapsed DLBCL (SPINOZA)

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

Lymphoma

United States
Asan Medical Center

Completed

Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia

Aplastic Anemia

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Imatinib Mesylate, Busulfan, Fludarabine, and Antithymocyte Globulin for CML Patients

Leukemia

United States
Sanofi

Completed

Insulin Glulisine in Adult Subjects With Type 2 Diabetes Receiving Insulin Glargine as Basal Insulin

Diabetes Mellitus, Type 2

United States
M.D. Anderson Cancer Center

Completed

Cellular Therapy With Cord Blood Cells

Lymphoma | Leukemia | Multiple Myeloma

United States
University of Florida
Accelerate Brain Cancer Cure; Lyla Nsouli Foundation

Active, not recruiting

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) (BRAVO)

Brain Stem Glioma | Diffuse Intrinsic Pontine Glioma (DIPG)

United States
St. Jude Children's Research Hospital
University of Miami

Completed

Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas

Neuroblastoma | Central Nervous System Tumors | Wilms Tumor | Lymphomas

United States
M.D. Anderson Cancer Center
Cytogen Corporation

Completed

Sm-EDTMP and Autologous Peripheral Blood Stem Cell Transplantation for Breast Cancer Patients With Bone Only Metastases

Breast Cancer | Bone Metastases

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) (SCURT)

Sickle Cell Disease

United States

Search clinical trials for: α-globin restored autologous hematopoietic stem cells

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